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MLDS grant Sabine Daemen

MLDS grant Sabine Daemen

15 November 2024

Dr Sabine Daemen (Dept of Internal Medicine) received a Career Development Grant (160k) from the Dutch Digestive Foundation (MLDS).

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Our new Division Leaders

Our new Division Leaders

3 October 2024

As of 1 October 2024, Casper Schalkwijk and Joost Lumens have been appointed as Division Leaders Vessels and Heart. Judith Sluimer will success Hugo ten Cate as Division Leader Blood in March 2025.

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Carim Maastricht
Carim Maastricht

Christian Weber

Professor

Prof. Christian Weber is the Chair in Vascular Medicine and the Director of the Institute for Cardiovascular Prevention at Ludwig-Maximilians-University (LMU) Munich, Germany, and Professor at the CARIM. After graduating and completing his training in internal medicine at LMU and Harvard Medical School, Boston, he was board-certified in clinical cardiology and appointed as a Chair in Molecular Cardiology at RWTH Aachen University. His group has a strong interest in the molecular interactions and patho-physiological functions of chemokines and immune cell subsets, as well as the role of microRNAs and their targets in vascular disease and atherosclerosis, while his clinical interests focus on developing novel biomarkers and biopharmaceuticals. He is the Spokesman of the DFG Collaborative Research Centre SFB1123 and coordinates the partner site Munich Heart Alliance in the German Centre for Cardiovascular Research (DZHK). Among numerous awards, he is a double ERC Advanced Investigator Grant recipient and Clarivate Analytics Highly Cited Researcher with more than 560 publications and an h-index of 97. He serves as the Editor-in-Chiefof Thrombosis&Haemostasis, Senior Associate Editor of Arteriosclerosis, Thrombosis & Vascular Biology andco-founderofCarolusTherapeutics Inc. and Cartesio Therapeutics Inc.

  • Vascular Immunotherapy, German Centre for Cardiovascular Research (BMBF DZHK
  • MHA VD1.2), 2019-2020
  • Munich Cluster for Systems Neurology (SyNergy), DFG Excellence Initiative, 2019-2026
  • ERC Advanced Grant °692511, PROVASC: Cell-specific vascular protection by CXCL12/CXCR4, 2016- 2022 ERC AdG
  • NIH 1R01HL122843, Molecular mechanisms linking CXCL12 to atherosclerosis, 2017-2020
  • DFG Collaborative Research Centre 1123 Atherosclerosis: new therapeutic targets, 2014-2022
Christian-weber

Department of Biochemistry
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht

  • 2024
    • Zhao, D., Han, C., Mammadova-Bach, E., Watanabe-Kusunoki, K., Bandeira Honda, T. S., Li, Y., Li, C., Li, Q., Long, H., Lyubenov, L., Shi, C., Santovito, D., Weber, C., Boor, P., Droste, P., Parikh, S., Shapiro, J., De Chiara, L., Carangelo, G., ... Anders, H.-J. (2024). Inhibition of complement factor C5a or C5aR for cholesterol crystal embolism-related vascular thrombosis with microvascular injury and its consequences. Kidney International, 106(5), 819-825. https://doi.org/10.1016/j.kint.2024.07.020
    • Döring, Y., van der Vorst, E. P. C., & Weber, C. (2024). Targeting immune cell recruitment in atherosclerosis. Nature reviews. Cardiology, 21(11), 824-840. https://doi.org/10.1038/s41569-024-01023-z
    • Santovito, D., Henderson, J. M., Bidzhekov, K., Triantafyllidou, V., Jansen, Y., Chen, Z., Farina, F. M., Diagel, A., Aslani, M., Blanchet, X., Schunkert, H., Megens, R. T. A., Doering, Y., Sattler, M., & Weber, C. (2024). Mex3a Protects Against Atherosclerosis: Evidence From Mice and Humans. Circulation, 150(15), 1213-1216. https://doi.org/10.1161/CIRCULATIONAHA.124.069526
    • Möller-Ramon, Z., Aslani, M., Sobczak, N., Hristov, M., Weber, C., Rot, A., & Duchêne, J. (2024). The 129 strain-derived passenger mutations in ACKR1-deficient mice alter the expression of PYHIN and Fc-gamma receptor genes. Journal of leukocyte biology. Advance online publication. https://doi.org/10.1093/jleuko/qiae208
    • Sachs, S., Götz, A., Finan, B., Feuchtinger, A., DiMarchi, R. D., Döring, Y., Weber, C., Tschöp, M. H., Müller, T. D., & Hofmann, S. M. (2024). Correction: GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease. Cardiovascular Diabetology, 23(1), Article 341. https://doi.org/10.1186/s12933-024-02407-8
    • Egea, V., Lutterberg, K., Steinritz, D., Rothmiller, S., Steinestel, K., Caca, J., Nerlich, A., Blum, H., Reschke, S., Khani, S., Bartelt, A., Worek, F., Thiermann, H., Weber, C., & Ries, C. (2024). Targeting miR-497-5p rescues human keratinocyte dysfunction upon skin exposure to sulfur mustard. Cell Death & Disease, 15(8), Article 585. https://doi.org/10.1038/s41419-024-06974-2
    • Wang, Y., Li, G., Chen, B., Shakir, G., Volz, M., van der Vorst, E. P. C., Maas, S. L., Geiger, M., Jethwa, C., Bartelt, A., Li, Z., Wettich, J., Sachs, N., Maegdefessel, L., Nazari Jahantigh, M., Hristov, M., Lacy, M., Lutz, B., Weber, C., ... Steffens, S. (2024). Myeloid cannabinoid CB1 receptor deletion confers atheroprotection in male mice by reducing macrophage proliferation in a sex-dependent manner. Cardiovascular Research, 120(12), 1411-1426. https://doi.org/10.1093/cvr/cvae125
    • Strohm, L., Daiber, A., Ubbens, H., Krishnankutty, R., Oelze, M., Kuntic, M., Hahad, O., Klein, V., Hoefer, I. E., von Kriegsheim, A., Kleinert, H., Atzler, D., Lurz, P., Weber, C., Wild, P. S., Münzel, T., Knosalla, C., Lutgens, E., & Daub, S. (2024). Role of inflammatory signaling pathways involving the CD40-CD40L-TRAF cascade in diabetes and hypertension-insights from animal and human studies. Basic Research in Cardiology, 119(4), 1-18. https://doi.org/10.1007/s00395-024-01045-1
    • Hristov, M., & Weber, C. (2024). Monocyte Subsets in Cardiovascular Disease: A Biomarker Perspective. Thrombosis and Haemostasis. Advance online publication. https://doi.org/10.1055/a-2348-5697
    • Parma, L., Duchene, J., & Weber, C. (2024). Breaking Point: How Intraplaque Hemorrhage Propels Plaque Rupture. Circulation Research, 135(2), 317-319. https://doi.org/10.1161/CIRCRESAHA.124.324795
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