Marleen van Greevenbroek

Associate professor

Dr Marleen van Greevenbroek is Medical Biologist (University of Utrecht, 1992) and Epidemiologist (Maastricht University, 2012). She received her PhD degree in 1997 at the University of Utrecht, on a thesis concerning the effects of fatty acids on the production of intestinal triglyceride-rich lipoproteins. In September 1997, she was appointed at the University of Maastricht (Dept. of Internal Medicine), where she was involved in studies on the metabolic and genetic aspects of obesity and cardiometabolic diseases.

Her main area of research is the identification of early events in the development of insulin resistance, type 2 diabetes, and cardiovascular disease. In recent years, her research activities specifically focused on the role of the complement system herein. This research encompasses both cohort studies and experimental work.

Department of Internal Medicine
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht

2024
- Mokhtar, S. B. A., Viljoen, J., van der Kallen, C. J. H., Berendschot, T. T. J. M., Dagnelie, P. C., Albers, J. D., Soeterboek, J., Scarpa, F., Colonna, A., van der Heide, F. C. T., van Greevenbroek, M. M. J., Bosm, H., Kroon, A. A., Nuijts, R. M. M. A., Gijs, M., Lakerveld, J., Malik, R. A., Webers, C. A. B., Stehouwer, C. D. A., & Koster, A. (2024). Greater exposure to PM<inf>2.5</inf> and PM<inf>10</inf> was associated with lower corneal nerve measures: the Maastricht study - a cross-sectional study. Environmental Health, 23(1), Article 70. https://doi.org/10.1186/s12940-024-01110-1
- van Hilten, A., van Rooij, J., Heijmans, B. T., ’t Hoen, P. A. C., Meurs, J. V., Jansen, R., Franke, L., Boomsma, D. I., Pool, R., van Dongen, J., Hottenga, J. J., van Greevenbroek, M. M. J., Stehouwer, C. D. A., van der Kallen, C. J. H., Schalkwijk, C. G., Wijmenga, C., Zhernakova, S., Tigchelaar, E. F., Slagboom, P. E., ... BIOS Consortium (2024). Phenotype prediction using biologically interpretable neural networks on multi-cohort multi-omics data. NPJ systems biology and applications, 10(1), Article 81. https://doi.org/10.1038/s41540-024-00405-w
- Heyens, L., Kenjic, H., Dagnelie, P., Schalkwijk, C., Stehouwer, C., Meex, S., Kooman, J., Bekers, O., van Greevenbroek, M., Savelberg, H., Robaeys, G., de Galan, B., Koster, A., van Dongen, M., Eussen, S., & Koek, G. (2024). Forns index and fatty liver index, but not FIB-4, are associated with indices of glycaemia, pre-diabetes and type 2 diabetes: analysis of The Maastricht Study. BMJ Open Gastroenterology, 11(1), Article e001466. https://doi.org/10.1136/bmjgast-2024-001466
- Meisters, R., Koster, A., Albers, J., Sezer, B., van Greevenbroek, M., de Galan, B., & Bosma, H. (2024). Early life socioeconomic inequalities and type 2 diabetes incidence: Longitudinal analyses in the Maastricht study. Diabetes Research and Clinical Practice, 217, Article 111855. https://doi.org/10.1016/j.diabres.2024.111855
- Coral, D. E., Smit, F., Farzaneh, A., Gieswinkel, A., Tajes, J. F., Sparsø, T., Delfin, C., Bauvain, P., Wang, K., Temprosa, M., De Cock, D., Blanch, J., Fernández-Real, J. M., Ramos, R., Ikram, M. K., Gomez, M. F., Kavousi, M., Panova-Noeva, M., Wild, P. S., ... Franks, P. W. (2024). Subclassification of obesity for precision prediction of cardiometabolic diseases. Nature Medicine. https://doi.org/10.1038/s41591-024-03299-7
- Soeterboek, J., Deckers, K., van Boxtel, M. P. J., Backes, W. H., Eussen, S. J. P. M., van Greevenbroek, M. M. J., Jansen, J. F. A., Koster, A., Schram, M. T., Stehouwer, C. D. A., Wesselius, A., Lakerveld, J., Bosma, H., & Köhler, S. (2024). Association of ambient air pollution with cognitive functioning and markers of structural brain damage: The Maastricht study. Environment International, 192, Article 109048. https://doi.org/10.1016/j.envint.2024.109048
- Chan, J. A., Koster, A., Lakerveld, J., Schram, M. T., van Greevenbroek, M., & Bosma, H. (2024). Associations of neighborhood social cohesion and changes in BMI-The Maastricht Study. European Journal of Public Health, 34(5), 949-954. https://doi.org/10.1093/eurpub/ckae109
- Sun, D., van Greevenbroek, M. M. J., Scheijen, J. L. J. M., Kelly, J., Schalkwijk, C. G., & Wouters, K. (2024). Methylglyoxal mediates the association between 2-hour plasma glucose and HbA1c with inflammation: The Maastricht Study. Journal of Clinical Endocrinology & Metabolism. Advance online publication. https://doi.org/10.1210/clinem/dgae640
- DeJong, N. R., Jansen, J. F. A., van Boxtel, M. P. J., Schram, M. T., Stehouwer, C. D. A., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Koster, A., Eussen, S. J. P. M., de Galan, B. E., Backes, W. H., & Köhler, S. (2024). Brain structure and connectivity mediate the association between lifestyle and cognition: The Maastricht Study. Brain Communications, 6(3), Article fcae171. https://doi.org/10.1093/braincomms/fcae171
- den Brok, E. J., Svensson, C. H., Panagiotou, M., van Greevenbroek, M. M. J., Mertens, P. R., Vazeou, A., Mitrakou, A., Makrilakis, K., Franssen, G. H. L. M., van Kuijk, S., Proennecke, S., Mougiakakou, S., Pedersen-Bjergaard, U., de Galan, B. E., & Melissa Consortium (2024). The effect of bolus advisors on glycaemic parameters in adults with diabetes on intensive insulin therapy: A systematic review with meta-analysis. Diabetes Obesity & Metabolism, 26(5), 1950-1961. https://doi.org/10.1111/dom.15521

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Team Science grant Uyen Nguyen and Roel Meiburg

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Marleen van Greevenbroek

Associate professor