Vanessa van Empel

Associate professor

Dr Vanessa van Empel studied Medicine at the University of Maastricht. During her studies, she started her PhD on the topic heart failure. She obtained her PhD from the University of Utrecht in 2007. Subsequently she started her training as a cardiologist at the Maastricht University Medical Centre. After finishing her cardiology training in 2011, Vanessa was rewarded the ICIN fellowship, which enabled her to do a post-doctoral fellowship at the Alfred Hospital in Melbourne, Australia, where she gained more expertise in the field of heart failure with preserved ejection fraction (HFpEF). She now is a staff member at the Maastricht UMC+ with an expertise in heart failure, and heart failure with preserved ejection fraction specifically.

Her clinical work and research has been dedicated to HFpEF. She initiated the HFpEF clinic in Maastricht, which started in 2015, and is responsible for the Maastricht HFpEF cohort. She obtained a grant 'Vrouwelijk Hartfalen' from the Health Foundation Limburg together with Prof. Blanche Schroen, is co-PI on the CVON project Early detection of HFpEF and is project leader of the CVON SHE-PREDICT-HF, which studies sex differences in HFpEF. These projects allow her to continue her research on HFpEF with special focus on cardiovascular imaging, biomarkers and microvascular dysfunction.

Department of Cardiology
P. Debeyelaan 25, 6229 HX Maastricht
PO Box 5800, 6202 AZ Maastricht
Room number: Maastricht UMC+ level 3
T: +31(0)43 387 70 95

2024
- Achten, A., Muller, S. A., Wijk, S. S., van der Meer, M. G., van der Harst, P., van Tintelen, P., Te Riele, A. S., van Empel, V., Oerlemans, M. I., & Knackstedt, C. (2024). Diversity of heart failure phenotypes in transthyretin amyloid cardiomyopathy. More than just heart failure with preserved ejection fraction. Annals of Medicine, 56(1), Article 2418965. https://doi.org/10.1080/07853890.2024.2418965
- Tobal, R., Potjewijd, J., de Vries, F., van Doorn, D. P. C., Jaminon, A., Bittner, R., Akbulut, C., van Empel, V., Heeringa, P., Damoiseaux, J., Schurgers, L., & van Paassen, P. (2024). Dephosphorylated uncarboxylated Matrix-Gla-Protein as candidate biomarker for immune-mediated vascular remodeling and prognosis in pulmonary hypertension. Scientific Reports, 14(1), Article 26633. https://doi.org/10.1038/s41598-024-77000-w
- Mourmans, S. G. J., Weerts, J., Baumert, M., Aizpurua, A. B., Achten, A., Knackstedt, C., Linz, D., & van Empel, V. P. M. (2024). Prognostic value of hypoxaemic burden from overnight oximetry in heart failure with preserved ejection fraction. Esc heart failure. Advance online publication. https://doi.org/10.1002/ehf2.15116
- Sikking, M. A., Harding, D., Henkens, M. T. H. M., Stroeks, S. L. V. M., Venner, M. F. G. H. M., Nihant, B., van Leeuwen, R. E. W., Fanti, S., Li, X., van Paassen, P., Knackstedt, C., Brunner-la Rocca, H.-P., van Empel, V. P. M., Verdonschot, J. A. J., Marelli-Berg, F. M., & Heymans, S. R. B. (2024). Cytotoxic T-Cells Drive Outcome in Inflammatory Dilated Cardiomyopathy. Circulation Research. Advance online publication. https://doi.org/10.1161/CIRCRESAHA.124.325183
- Woudstra, J., Mourmans, S. G. J., Vink, C. E. M., Marques, K. M. J., de Jong, E., Haddad, R. Y. R., van de Hoef, T. P., Chamuleau, S. A. J., Damman, P., Beijk, M. A. M., van Empel, V., Serné, E. H., Appelman, Y., & Eringa, E. C. (2024). Relationship between peripheral and intracoronary blood flow in patients with angina and non-obstructive coronary arteries. American Journal of Physiology-heart and Circulatory Physiology, 327(4), H1086-H1097. https://doi.org/10.1152/ajpheart.00335.2024
- Achten, A., van Empel, V. P. M., Weerts, J., Mourmans, S., Beckers-Wesche, F., Spanjers, M., Gingele, A., Brunner-La Rocca, H.-P., Sanders-van Wijk, S., & Knackstedt, C. (2024). Changes in the diagnostic trajectory of transthyretin cardiac amyloidosis over six years. Heart and Vessels, 39(10), 857-866. https://doi.org/10.1007/s00380-024-02408-3
- Dib, M. J., Azzo, J. D., Zhao, L., Salman, O., Gan, S., De Buyzere, M. L., De Meyer, T., Ebert, C., Gunawardhana, K., Liu, L., Gordon, D., Seiffert, D., Ching-Pin, C., Zamani, P., Cohen, J. B., Pourmussa, B., Kun, S., Gill, D., Burgess, S., ... Chirinos, J. A. (2024). Proteome-Wide Genetic Investigation of Large Artery Stiffness. JACC: Basic to Translational Science, 9(10), 1178-1191. https://doi.org/10.1016/j.jacbts.2024.05.017
- Salman, O., Zamani, P., Zhao, L., Dib, M. J., Gan, S., Azzo, J. D., Pourmussa, B., Richards, A. M., Javaheri, A., Mann, D. L., Rietzschel, E., Zhao, M., Wang, Z., Ebert, C., Liu, L., Gunawardhana, K. L., Greenawalt, D., Carayannopoulos, L., Chang, C. P., ... Chirinos, J. A. (2024). Prognostic Significance and Biologic Associations of Senescence-Associated Secretory Phenotype Biomarkers in Heart Failure. Journal of the American Heart Association, 13(17), Article e033675. https://doi.org/10.1161/JAHA.123.033675
- Salman, O., Zhao, L., Cohen, J. B., Dib, M. J., Azzo, J. D., Gan, S., Richards, A. M., Pourmussa, B., Doughty, R., Javaheri, A., Mann, D. L., Rietzschel, E., Zhao, M., Wang, Z., Ebert, C., van Empel, V., Kammerhoff, K., Maranville, J., Gogain, J., ... Chirinos, J. A. (2024). Proteomic Correlates and Prognostic Significance of Kidney Injury in Heart Failure With Preserved Ejection Fraction. Journal of the American Heart Association, 13(17), Article e033660. https://doi.org/10.1161/JAHA.123.033660
- Tobal, R., Potjewijd, J., van Doorn, D. P. C., van Empel, V., Damoiseaux, J., & van Paassen, P. (2024). High Prevalence of Myositis-Specific and Associated Antibodies in Patients with Pulmonary Hypertension. Diagnostics, 14(14), Article 1471. https://doi.org/10.3390/diagnostics14141471

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Vanessa van Empel

Associate professor