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CARIM's Confidential Contact Persons

CARIM's Confidential Contact Persons

27 November 2024

Dr Magdi Nagy (Dept of Biochemistry) and Prof. Peter de Leeuw (Dept of Internal Medicine) have been appointed as CARIM Confidential Contact Persons.

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ZonMw grant on appropriate palliative care

ZonMw grant on appropriate palliative care

27 November 2024

Prof. Marc Hemmelder (Dept of Internal Medicine) and his team received a ZonMw grant to promote early palliative care for dialysis patients who are non-waitlisted for transplantation.

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Carim Maastricht
Carim Maastricht

Christian Weber

Professor

Prof. Christian Weber is the Chair in Vascular Medicine and the Director of the Institute for Cardiovascular Prevention at Ludwig-Maximilians-University (LMU) Munich, Germany, and Professor at the CARIM. After graduating and completing his training in internal medicine at LMU and Harvard Medical School, Boston, he was board-certified in clinical cardiology and appointed as a Chair in Molecular Cardiology at RWTH Aachen University. His group has a strong interest in the molecular interactions and patho-physiological functions of chemokines and immune cell subsets, as well as the role of microRNAs and their targets in vascular disease and atherosclerosis, while his clinical interests focus on developing novel biomarkers and biopharmaceuticals. He is the Spokesman of the DFG Collaborative Research Centre SFB1123 and coordinates the partner site Munich Heart Alliance in the German Centre for Cardiovascular Research (DZHK). Among numerous awards, he is a double ERC Advanced Investigator Grant recipient and Clarivate Analytics Highly Cited Researcher with more than 560 publications and an h-index of 97. He serves as the Editor-in-Chiefof Thrombosis&Haemostasis, Senior Associate Editor of Arteriosclerosis, Thrombosis & Vascular Biology andco-founderofCarolusTherapeutics Inc. and Cartesio Therapeutics Inc.

  • Vascular Immunotherapy, German Centre for Cardiovascular Research (BMBF DZHK
  • MHA VD1.2), 2019-2020
  • Munich Cluster for Systems Neurology (SyNergy), DFG Excellence Initiative, 2019-2026
  • ERC Advanced Grant °692511, PROVASC: Cell-specific vascular protection by CXCL12/CXCR4, 2016- 2022 ERC AdG
  • NIH 1R01HL122843, Molecular mechanisms linking CXCL12 to atherosclerosis, 2017-2020
  • DFG Collaborative Research Centre 1123 Atherosclerosis: new therapeutic targets, 2014-2022
Christian-weber

Department of Biochemistry
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht

  • 2020
    • Hinkel, R., Ramanujam, D., Kaczmarek, V., Howe, A., Klett, K., Beck, C., Dueck, A., Thum, T., Laugwitz, K.-L., Maegdefessel, L., Weber, C., Kupatt, C., & Engelhardt, S. (2020). AntimiR-21 Prevents Myocardial Dysfunction in a Pig Model of Ischemia/Reperfusion Injury. Journal of the American College of Cardiology, 75(15), 1788-1800. https://doi.org/10.1016/j.jacc.2020.02.041
    • Eckardt, V., Miller, M. C., Blanchet, X., Duan, R., Leberzammer, J., Duchene, J., Soehnlein, O., Megens, R. T. A., Ludwig, A.-K., Dregni, A., Faussner, A., Wichapong, K., Ippel, H., Dijkgraaf, I., Kaltner, H., Doering, Y., Bidzhekov, K., Hackeng, T. M., Weber, C., ... Mayo, K. H. (2020). Chemokines and galectins form heterodimers to modulate inflammation. Embo Reports, 21(4), Article 47852. https://doi.org/10.15252/embr.201947852
    • Weber, C. (2020). The ESC Council on Basic Cardiovascular Science. European Heart Journal, 41(12), 1227-1230. https://doi.org/10.1093/eurheartj/ehaa189
    • Doering, Y., Jansen, Y., Cimen, I., Aslani, M., Gencer, S., Peters, L. J. F., Duchene, J., Weber, C., & van der Vorst, E. P. C. (2020). B-Cell-Specific CXCR4 Protects Against Atherosclerosis Development and Increases Plasma IgM Levels. Circulation Research, 126(6), 787-788. https://doi.org/10.1161/CIRCRESAHA.119.316142
    • van der Vorst, E. P. C., Daissormont, I., Aslani, M., Seijkens, T., Wijnands, E., Lutgens, E., Duchene, J., Santovito, D., Doering, Y., Halvorsen, B., Aukrust, P., Weber, C., Hoepken, U. E., & Biessen, E. A. L. (2020). Interruption of the CXCL13/CXCR5 Chemokine Axis Enhances Plasma IgM Levels and Attenuates Atherosclerosis Development. Thrombosis and Haemostasis, 120(2), 344-347. https://doi.org/10.1055/s-0039-3400746
    • Butt, E., Stempfle, K., Lister, L., Wolf, F., Kraft, M., Herrmann, A. B., Viciano, C. P., Weber, C., Hochhaus, A., Ernst, T., Hoffmann, C., Zernecke, A., & Frietsch, J. J. (2020). Phosphorylation-Dependent Differences in CXCR4-LASP1-AKT1 Interaction between Breast Cancer and Chronic Myeloid Leukemia. Cells, 9(2), Article 444. https://doi.org/10.3390/cells9020444
    • Adrover, J. M., Aroca-Crevillen, A., Crainiciuc, G., Ostos, F., Rojas-Vega, Y., Rubio-Ponce, A., Cilloniz, C., Bonzon-Kulichenko, E., Calvo, E., Rico, D., Moro, M. A., Weber, C., Lizasoain, I., Torres, A., Ruiz-Cabello, J., Vazquez, J., & Hidalgo, A. (2020). Programmed 'disarming' of the neutrophil proteome reduces the magnitude of inflammation. Nature Immunology, 21(2), 135-144. https://doi.org/10.1038/s41590-019-0571-2
    • Lip, G. Y. H., Rigby, A., & Weber, C. (2020). A Toast to the Last Decade and a Very Happy 2020 from Thrombosis and Haemostasis!Thrombosis and Haemostasis, 120(1), 1-4. https://doi.org/10.1055/s-0039-3402054
    • Tilstam, P., Soppert, J., Hemmers, C., Harlacher, E., Doering, Y., van der Vorst, E. P. C., Schulte, C., Alampour-Rajabi, S., Theelen, W., Asare, Y., de Winther, M. P. J., Lawrence, T., Bernhagen, J., Schober, A., Zernecke, A., Jankowski, J., Weber, C., & Noels, H. (2020). Non-activatable mutant of inhibitor of kappa B kinase α (IKKα) exerts vascular site-specific effects on atherosclerosis in Apoe-deficient mice. Atherosclerosis, 292, 23-30. https://doi.org/10.1016/j.atherosclerosis.2019.10.023
    • Weber, C., Rigby, A., & Lip, G. Y. H. (2020). Thrombosis and Haemostasis 2019 Editor's Choice Papers. Thrombosis and Haemostasis, 120(1), 184-189. https://doi.org/10.1055/s-0039-3402055
  • 2019
    • Lutgens, E., Atzler, D., Doering, Y., Duchene, J., Steffens, S., & Weber, C. (2019). Immunotherapy for cardiovascular disease. European Heart Journal, 40(48), 3937-3946. https://doi.org/10.1093/eurheartj/ehz283
    • Goldmann, L., Duan, R., Kragh, T., Wittmann, G., Weber, C., Lorenz, R., von Hundelshausen, P., Spannagl, M., & Siess, W. (2019). Oral Bruton tyrosine kinase inhibitors block activation of the platelet Fc receptor CD32a (FcγRIIA): a new option in HIT?Blood advances, 3(23), 4021-4033. https://doi.org/10.1182/bloodadvances.2019000617
    • Cimen, I., Yildirim, Z., Dogan, A. E., Yildirim, A. D., Tufanli, O., Onat, U. I., UyenThao Nguyen, Watkins, S. M., Weber, C., & Erbay, E. (2019). Double bond configuration of palmitoleate is critical for atheroprotection. Molecular Metabolism, 28, 58-72. https://doi.org/10.1016/j.molmet.2019.08.004
    • Busygina, K., Denzinger, V., Bernlochner, I., Weber, C., Lorenz, R., & Siess, W. (2019). Btk Inhibitors as First Oral Atherothrombosis-Selective Antiplatelet Drugs?Thrombosis and Haemostasis, 119(8), 1212-1221. https://doi.org/10.1055/s-0039-1687877
    • Natarelli, L., & Weber, C. (2019). Next-Generation Therapeutic Concepts for Atherosclerosis: Focus on Cell Specificity and Noncoding RNAs. Thrombosis and Haemostasis, 119(8), 1199-1201. https://doi.org/10.1055/s-0039-1693412
    • Nagy, M., van Geffen, J. P., Stegner, D., Adams, D. J., Braun, A., de Witt, S. M., Elvers, M., Geer, M. J., Kuijpers, M. J. E., Kunzelmann, K., Mori, J., Oury, C., Pircher, J., Pleines, I., Poole, A. W., Senis, Y. A., Verdoold, R., Weber, C., Nieswandt, B., ... Baaten, C. C. F. M. J. (2019). Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis. Frontiers in Cardiovascular Medicine, 6, Article 99. https://doi.org/10.3389/fcvm.2019.00099
    • Ketelhuth, D. F. J., Lutgens, E., Back, M., Binder, C. J., Van den Bossche, J., Daniel, C., Dumitriu, I. E., Hoefer, I., Libby, P., O'Neill, L., Weber, C., & Evans, P. C. (2019). Immunometabolism and atherosclerosis: perspectives and clinical significance: a position paper from the Working Group on Atherosclerosis and Vascular Biology of the European Society of Cardiology. Cardiovascular Research, 115(9), 1385-1392. https://doi.org/10.1093/cvr/cvz166
    • Bianchini, M., Duchene, J., Santovito, D., Schloss, M. J., Evrard, M., Winkels, H., Aslani, M., Mohanta, S. K., Horckmans, M., Blanchet, X., Lacy, M., von Hundelshausen, P., Atzler, D., Habenicht, A., Gerdes, N., Pelisek, J., Ng, L. G., Steffens, S., Weber, C., & Megens, R. T. A. (2019). PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function. Science Immunology, 4(36), Article eaar3054. https://doi.org/10.1126/sciimmunol.aar3054
    • van der Vorst, E. P. C., Peters, L. J. F., Mueller, M., Gencer, S., Yan, Y., Weber, C., & Döring , Y. (2019). G-Protein Coupled Receptor Targeting on Myeloid Cells in Atherosclerosis. Frontiers in Pharmacology, 10(MAY), Article 531. https://doi.org/10.3389/fphar.2019.00531
    • Silvestre-Roig, C., Braster, Q., Wichapong, K., Lee, E. Y., Marie Teulon, J., Berrebeh, N., Winter, J., Adrover, J. M., Santos, G. S., Froese, A., Lemnitzer, P., Ortega-Gomez, A., Chevre, R., Marschner, J., Schumski, A., Winter, C., Perez-Olivares, L., Pan, C., Paulin, N., ... Soehnlein, O. (2019). Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death. Nature, 569(7755), 236-240. https://doi.org/10.1038/s41586-019-1167-6
    • Gencer, S., van der Vorst, E. P. C., Aslani, M., Weber, C., Döring, Y., & Duchene, J. (2019). Atypical Chemokine Receptors in Cardiovascular Disease. Thrombosis and Haemostasis, 119(4), 534-541. https://doi.org/10.1055/s-0038-1676988
    • Noels, H., Weber, C., & Koenen, R. R. (2019). Chemokines as Therapeutic Targets in Cardiovascular Disease The Road Behind, The Road Ahead. Arteriosclerosis Thrombosis and Vascular Biology, 39(4), 583-592. https://doi.org/10.1161/ATVBAHA.118.312037
    • van der Vorst, E. P. C., Mandl, M., Mueller, M., Neideck, C., Jansen, Y., Hristov, M., Gencer, S., Peters, L. J. F., Meiler, S., Feld, M., Geiselhoeringer, A.-L., de Jong, R. J., Ohnmacht, C., Noels, H., Soehnlein, O., Drechsler, M., Weber, C., & Doering, Y. (2019). Hematopoietic ChemR23 (Chemerin Receptor 23) Fuels Atherosclerosis by Sustaining an M1 Macrophage-Phenotype and Guidance of Plasmacytoid Dendritic Cells to Murine Lesions-Brief Report. Arteriosclerosis Thrombosis and Vascular Biology, 39(4), 685-693. https://doi.org/10.1161/ATVBAHA.119.312386
    • Steffens, S., & Weber, C. (2019). Immunotherapy for Atherosclerosis-Novel Concepts. Thrombosis and Haemostasis, 119(4), 515-516. https://doi.org/10.1055/s-0039-1683451
    • Döring, Y., van der Vorst, E. P. C., Duchene, J., Jansen, Y., Gencer, S., Bidzhekov, K., Atzler, D., Santovito, D., Rader, D. J., Saleheen, D., & Weber, C. (2019). CXCL12 Derived From Endothelial Cells Promotes Atherosclerosis to Drive Coronary Artery Disease. Circulation, 139(10), 1338-1340. https://doi.org/10.1161/CIRCULATIONAHA.118.037953
    • Cremer, S., Michalik, K. M., Fischer, A., Pfisterer, L., Jae, N., Winter, C., Boon, R. A., Muhly-Reinholz, M., John, D., Uchida, S., Weber, C., Poller, W., Guenther, S., Braun, T., Li, D. Y., Maegdefessel, L., Matic, L. P., Hedin, U., Soehnlein, O., ... Dimmeler, S. (2019). Hematopoietic Deficiency of the Long Noncoding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation. Circulation, 139(10), 1320-1334. https://doi.org/10.1161/circulationaha.117.029015
    • Yin, C., Ackermann, S., Ma, Z., Mohanta, S. K., Zhang, C., Li, Y., Nietzsche, S., Westermann, M., Peng, L., Hu, D., Bontha, S. V., Srikakulapu, P., Beer, M., Megens, R. T. A., Steffens, S., Hildner, M., Halder, L. D., Eckstein, H.-H., Pelisek, J., ... Habenicht, A. J. R. (2019). ApoE attenuates unresolvable inflammation by complex formation with activated C1q. Nature Medicine, 25(3), 496-506. https://doi.org/10.1038/s41591-018-0336-8
    • Schloss, M. J., Horckmans, M., Guillamat-Prats, R., Hering, D., Lauer, E., Lenglet, S., Weber, C., Thomas, A., & Steffens, S. (2019). 2-Arachidonoylglycerol mobilizes myeloid cells and worsens heart function after acute myocardial infarction. Cardiovascular Research, 115(3), 602-613. https://doi.org/10.1093/cvr/cvy242
    • Denzinger, V., Busygina, K., Jamasbi, J., Pekrul, I., Spannagl, M., Weber, C., Lorenz, R., & Siess, W. (2019). Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS-4059, BGB-3111 and Evobrutinib. Thrombosis and Haemostasis, 119(3), 397-406. https://doi.org/10.1055/s-0039-1677744
    • Yin, C., Ackermann, S., Ma, Z., Mohanta, S. K., Zhang, C., Li, Y., Nietzsche, S., Westermann, M., Peng, L., Hu, D., Bontha, S. V., Srikakulapu, P., Beer, M., Megens, R. T. A., Steffens, S., Hildner, M., Halder, L. D., Eckstein, H.-H., Pelisek, J., ... Habenicht, A. J. R. (2019). Publisher Correction: ApoE attenuates unresolvable inflammation by complex formation with activated C1q. Nature Medicine, 25(3), 529-529. https://doi.org/10.1038/s41591-019-0378-6
    • Adrover, J. M., del Fresno, C., Crainiciuc, G., Isabel Cuartero, M., Casanova-Acebes, M., Weiss, L. A., Huerga-Encabo, H., Silvestre-Roig, C., Rossaint, J., Cossio, I., Lechuga-Vieco, A. V., Garcia-Prieto, J., Gomez-Parrizas, M., Quintana, J. A., Ballesteros, I., Martin-Salamanca, S., Aroca-Crevillen, A., Chong, S. Z., Evrard, M., ... Hidalgo, A. (2019). A Neutrophil Timer Coordinates Immune Defense and Vascular Protection. Immunity, 50(2), 390-402.e10. https://doi.org/10.1016/j.immuni.2019.01.002
    • Pfeiler, S., Thakur, M., Gruenauer, P., Megens, R. T. A., Joshi, U., Coletti, R., Samara, V., Mueller-Stoy, G., Ishikawa-Ankerhold, H., Stark, K., Klingl, A., Froehlich, T., Arnold, G. J., Woermann, S., Bruns, C. J., Alguel, H., Weber, C., Massberg, S., & Engelmann, B. (2019). CD36-triggered cell invasion and persistent tissue colonization by tumor microvesicles during metastasis. Faseb Journal, 33(2), 1860-1872. https://doi.org/10.1096/fj.201800985R
    • Prats, R. G., Rami, M., Ring, L., Rinne, P., Lauer, E., Lenglet, S., Thomas, A., Pagano, S., Vuilleumier, N., Cravatt, B. F., Weber, C., Faussner, A., & Steffens, S. (2019). Deficiency of Monoacylglycerol Lipase Enhances IgM Plasma Levels and Limits Atherogenesis in a CB2-Dependent Manner. Thrombosis and Haemostasis, 119(2), 348-351. https://doi.org/10.1055/s-0038-1676769
    • van der Vorst, E. P. C., & Weber, C. (2019). Novel Features of Monocytes and Macrophages in Cardiovascular Biology and Disease. Arteriosclerosis Thrombosis and Vascular Biology, 39(2), E30-E37. https://doi.org/10.1161/ATVBAHA.118.312002
    • Seijkens, T. T. P., Poels, K., Meiler, S., van Tiel, C. M., Kusters, P. J. H., Reiche, M., Atzler, D., Winkels, H., Tjwa, M., Poelman, H., Slutter, B., Kuiper, J., Gijbels, M., Kuivenhoven, J. A., Matic, L. P., Paulsson-Berne, G., Hedin, U., Hansson, G. K., Nicolaes, G. A. F., ... Lutgens, E. (2019). Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8(+) T cell-mediated macrophage death. European Heart Journal, 40(4), 372-382. https://doi.org/10.1093/eurheartj/ehy714
    • Kiouptsi, K., Jaeckel, S., Pontarollo, G., Grill, A., Kuijpers, M. J. E., Wilms, E., Weber, C., Sommer, F., Nagy, M., Neideck, C., Jansen, Y., Ascher, S., Formes, H., Karwot, C., Bayer, F., Kollar, B., Subramaniam, S., Molitor, M., Wenzel, P., ... Reinhardt, C. (2019). The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice. Mbio, 10(5), Article e02298-19. https://doi.org/10.1128/mBio.02298-19
  • 2018
    • Stocker, T. J., Pircher, J., Skenderi, A., Ehrlich, A., Eberle, C., Megens, R. T. A., Petzold, T., Zhang, Z., Walzog, B., Mueller-Taubenberger, A., Weber, C., Massberg, S., Ishikawa-Ankerhold, H., & Schulz, C. (2018). The Actin Regulator Coronin-1A Modulates Platelet Shape Change and Consolidates Arterial Thrombosis. Thrombosis and Haemostasis, 118(12), 2098-2111. https://doi.org/10.1055/s-0038-1675604
    • Braza, M. S., van Leent, M. M. T., Lameijer, M., Sanchez-Gaytan, B. L., Arts, R. J. W., Perez-Medina, C., Conde, P., Garcia, M. R., Gonzalez-Perez, M., Brahmachary, M., Fay, F., Kluza, E., Kossatz, S., Dress, R. J., Salem, F., Rialdi, A., Reiner, T., Boros, P., Strijkers, G. J., ... Ochando, J. (2018). Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance. Immunity, 49(5), 819-828.e6. https://doi.org/10.1016/j.immuni.2018.09.008
    • Casanova-Acebes, M., Nicolas-Avila, J. A., Li, J. L., Garcia-Silva, S., Balachander, A., Rubio-Ponce, A., Weiss, L. A., Adrover, J. M., Burrows, K., A-Gonzalez, N., Ballesteros, I., Devi, S., Quintana, J. A., Crainiciuc, G., Leiva, M., Gunzer, M., Weber, C., Nagasawa, T., Soehnlein, O., ... Hidalgo, A. (2018). Neutrophils instruct homeostatic and pathological states in naive tissues. Journal of Experimental Medicine, 215(11), 2778-2795. https://doi.org/10.1084/jem.20181468
    • Rinne, P., Guillamat-Prats, R., Rami, M., Bindila, L., Ring, L., Lyytikainen, L.-P., Raitoharju, E., Oksala, N., Lehtimaki, T., Weber, C., van der Vorst, E. P. C., & Steffens, S. (2018). Palmitoylethanolamide Promotes a Proresolving Macrophage Phenotype and Attenuates Atherosclerotic Plaque Formation. Arteriosclerosis Thrombosis and Vascular Biology, 38(11), 2562-2575. https://doi.org/10.1161/ATVBAHA.118.311185
    • Schmitz, C., Noels, H., El Bounkari, O., Straussfeld, E., Megens, R. T. A., Sternkopf, M., Alampour-Rajabi, S., Krammer, C., Tilstam, P. V., Gerdes, N., Burger, C., Kapurniotu, A., Bucala, R., Jankowski, J., Weber, C., & Bernhagen, J. (2018). Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis. Faseb Journal, 32(8), 4428-4443. https://doi.org/10.1096/fj.201800058R
    • Vajen, T., Koenen, R. R., Werner, I., Staudt, M., Projahn, D., Curaj, A., Sonmez, T. T., Simsekyilmaz, S., Schumacher, D., Mollmann, J., Hackeng, T. M., von Hundelshausen, P., Weber, C., & Liehn, E. A. (2018). Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis. Scientific Reports, 8(1), Article 10647. https://doi.org/10.1038/s41598-018-29026-0
    • Domschke, G., Linden, F., Pawig, L., Hafner, A., Akhavanpoor, M., Reymann, J., Doesch, A. O., Erbel, C., Weber, C., Katus, H. A., Noels, H., Erfle, H., Gleissner, C. A., & Runz, H. (2018). Systematic RNA-interference in primary human monocyte-derived macrophages: A high-throughput platform to study foam cell formation. Scientific Reports, 8(1), Article 10516. https://doi.org/10.1038/s41598-018-28790-3
    • Winter, C., Silvestre-Roig, C., Ortega-Gomez, A., Lemnitzer, P., Poelman, H., Schumski, A., Winter, J., Drechsler, M., de Jong, R., Immler, R., Sperandio, M., Hristov, M., Zeller, T., Nicolaes, G. A. F., Weber, C., Viola, J. R., Hidalgo, A., Scheiermann, C., & Soehnlein, O. (2018). Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis. Cell Metabolism, 28(1), 175-182.e5. https://doi.org/10.1016/j.cmet.2018.05.002
    • van der Vorst, E. P. C., Weber, C., & Donners, M. M. P. C. (2018). A Disintegrin and Metalloproteases (ADAMs) in Cardiovascular, Metabolic and Inflammatory Diseases: Aspects for Theranostic Approaches. Thrombosis and Haemostasis, 118(7), 1167-1175. https://doi.org/10.1055/s-0038-1660479
    • van der Vorst, E. P. C., & Weber, C. (2018). Metabolomic profiling of atherosclerotic plaques: towards improved cardiovascular risk stratification. European Heart Journal, 39(24), 2311-2313. https://doi.org/10.1093/eurheartj/ehy117
    • Busygina, K., Jamasbi, J., Seiler, T., Deckmyn, H., Weber, C., Brandl, R., Lorenz, R., & Siess, W. (2018). Oral Bruton tyrosine kinase inhibitors selectively block atherosclerotic plaque-triggered thrombus formation in humans. Blood, 131(24), 2605-2616. https://doi.org/10.1182/blood-2017-09-808808
    • Tunon, J., Back, M., Badimon, L., Bochaton-Piallat, M.-L., Cariou, B., Daemen, M. J., Egido, J., Evans, P. C., Francis, S. E., Ketelhuth, D. F. J., Lutgens, E., Matter, C. M., Monaco, C., Steffens, S., Stroes, E., Vindis, C., Weber, C., Hoefer, I. E., & ESC Working Grp Atherosclerosis (2018). Interplay between hypercholesterolaemia and inflammation in atherosclerosis: Translating experimental targets into clinical practice. European Journal of Preventive Cardiology, 25(9), 948-955. https://doi.org/10.1177/2047487318773384
    • Rami, M., Guillamat-Prats, R., Rinne, P., Salvermoser, M., Ring, L., Bianchini, M., Blanchet, X., Megens, R. T. A., Doring, Y., Walzog, B., Soehnlein, O., Weber, C., Faussner, A., & Steffens, S. (2018). Chronic Intake of the Selective Serotonin Reuptake Inhibitor Fluoxetine Enhances Atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology, 38(5), 1007-1019. https://doi.org/10.1161/ATVBAHA.117.310536
    • Lacy, M., Kontos, C., Brandhofer, M., Hille, K., Groning, S., Sinitski, D., Bourilhon, P., Rosenberg, E., Krammer, C., Thavayogarajah, T., Pantouris, G., Bakou, M., Weber, C., Lolis, E., Bernhagen, J., & Kapurniotu, A. (2018). Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4. Scientific Reports, 8(1), Article 5171. https://doi.org/10.1038/s41598-018-23554-5
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