• 2012
    • Doering, Y., Manthey, H. D., Drechsler, M., Lievens, D., Megens, R. T. A., Soehnlein, O., Busch, M., Manca, M., Koenen, R. R., Pelisek, J., Daemen, M. J., Lutgens, E., Zenke, M., Binder, C. J., Weber, C., & Zernecke, A. (2012). Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis. Circulation, 125(13), 1673-U190. https://doi.org/10.1161/CIRCULATIONAHA.111.046755
    • Segers, F. M. E., Yu, H., Molenaar, T. J. M., Prince, P., Tanaka, T., van Berkel, T. J. C., & Biessen, E. A. L. (2012). Design and Validation of a Specific Scavenger Receptor Class AI Binding Peptide for Targeting the Inflammatory Atherosclerotic Plaque. Arteriosclerosis Thrombosis and Vascular Biology, 32(4), 971-U285. https://doi.org/10.1161/ATVBAHA.111.235358
    • Bidzhekov, K., Gan, L., Denecke, B., Rostalsky, A., Hristov, M., Koeppel, T. A., Zernecke, A., & Weber, C. (2012). microRNA expression signatures and parallels between monocyte subsets and atherosclerotic plaque in humans. Thrombosis and Haemostasis, 107(4), 619-625. https://doi.org/10.1160/TH11-09-0607
    • Takx, R. A. P., Moscariello, A., Schoepf, U. J., Barraza, J. M. J., Nance, J. W. . J., Bastarrika, G., Das, M., Meyer, M., Wildberger, J. E., Schoenberg, S. O., Fink, C., & Henzler, T. (2012). Quantification of left and right ventricular function and myocardial mass: Comparison of low-radiation dose 2nd generation dual-source CT and cardiac MRI. European Journal of Radiology, 81(4), E598-E604. https://doi.org/10.1016/j.ejrad.2011.07.001
    • Grommes, J., Alard, J.-E., Drechsler, M., Wantha, S., Morgelin, M., Kuebler, W. M., Jacobs, M., von Hundelshausen, P., Markart, P., Wygrecka, M., Preissner, K. T., Hackeng, T. M., Koenen, R. R., Weber, C., & Soehnlein, O. (2012). Disruption of Platelet-derived Chemokine Heteromers Prevents Neutrophil Extravasation in Acute Lung Injury. American Journal of Respiratory and Critical Care Medicine, 185(6), 628-636. https://doi.org/10.1164/rccm.201108-1533OC
    • Versluis, B., Dremmen, M. H. G., Nelemans, P. J., Wildberger, J. E., Schurink, G.-W., Leiner, T., & Backes, W. H. (2012). MRI of Arterial Flow Reserve in Patients with Intermittent Claudication: Feasibility and Initial Experience. PLOS ONE, 7(3), Article e31514. https://doi.org/10.1371/journal.pone.0031514
    • Dittmar, R., Potier, E., van Zandvoort, M., & Ito, K. (2012). Assessment of Cell Viability in Three-Dimensional Scaffolds Using Cellular Auto-Fluorescence. Tissue Engineering. Part C. Methods , 18(3), 198-204. https://doi.org/10.1089/ten.tec.2011.0334
    • Megens, R. T. A., Vijayan, S., Lievens, D., Doering, Y., van Zandvoort, M. A. M. J., Grommes, J., Weber, C., & Soehnlein, O. (2012). Presence of luminal neutrophil extracellular traps in atherosclerosis. Thrombosis and Haemostasis, 107(3), 597-598. https://doi.org/10.1160/TH11-09-0650
    • van de Weijer, T., van Ewijk, P. A., Zandbergen, H. R., Slenter, J. M., Kessels, A. G., Wildberger, J. E., Hesselink, M. K. C., Schrauwen, P., Schrauwen-Hinderling, V. B., & Kooi, M. E. (2012). Geometrical models for cardiac MRI in rodents: comparison of quantification of left ventricular volumes and function by various geometrical models with a full-volume MRI data set in rodents.American Journal of Physiology-heart and Circulatory Physiology, 302(3), H709-H715. https://doi.org/10.1152/ajpheart.00710.2011
    • Knottnerus, I. L. H., Winckers, K., ten Cate, H., Hackeng, T. M., Lodder, J., Rouhl, R. P. W., Staals, J., Govers-Riemslag, J. W. P., Bekers, O., & van Oostenbrugge, R. J. (2012). Levels of heparin-releasable TFPI are increased in first-ever lacunar stroke patients. Neurology, 78(7), 493-498. https://doi.org/10.1212/WNL.0b013e318246d6b7
    • Rowinska, Z., Zander, S., Zernecke, A., Jacobs, M., Langer, S., Weber, C., Merx, M. W., & Koeppel, T. A. (2012). Non- invasive in vivo analysis of a murine aortic graft using high resolution ultrasound microimaging. European Journal of Radiology, 81(2), 244-249. https://doi.org/10.1016/j.ejrad.2010.12.083
    • Doering, Y., Noels, H., & Weber, C. (2012). The Use of High-Throughput Technologies to Investigate Vascular Inflammation and Atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology, 32(2), 182-195. https://doi.org/10.1161/ATVBAHA.111.232686
    • Goossens, G. H., Essers, Y., Konings, E., Jocken, J. W. E., Blaak, E. E., Bizzarri, A., Cajlakovic, M., Ribitsch, V., Clement, K., Venteclef, N., & Cleutjens, J. P. (2012). Response to Letter Regarding Article, "Increased Adipose Tissue Oxygen Tension in Obese Compared With Lean Men Is Accompanied by Insulin Resistance, Impaired Adipose Tissue Capillarization, and Inflammation". Circulation, 125(4), E316-E316. https://doi.org/10.1161/CIRCULATIONAHA.111.068452
    • Huijts, M., Duits, A., Staals, J., & van Oostenbrugge, R. J. (2012). Association of Vitamin B12 Deficiency with Fatigue and Depression after Lacunar Stroke. PLOS ONE, 7(1), Article e30519. https://doi.org/10.1371/journal.pone.0030519
    • Yu, H., Bot, I., Sliedregt-Bol, K., Xu, X., Bot, M., van Heiningen, S. H., van der Marel, G. A., Bennett, M. R., Overkleeft, H., van Berkel, T. J. C., & Biessen, E. A. L. (2012). Selective Modulation of Nuclear Factor of Activated T-Cell Function in Restenosis by a Potent Bipartite Peptide Inhibitor. Circulation Research, 110(2), 200–210. https://doi.org/10.1161/CIRCRESAHA.111.240895
    • Bieri, M., Mobbs, J. I., Koay, A., Louey, G., Mok, Y.-F., Hatters, D. M., Park, J.-T., Park, K.-H., Neumann, D., Stapleton, D., & Gooley, P. R. (2012). AMP-Activated Protein Kinase beta-Subunit Requires Internal Motion for Optimal Carbohydrate Binding. Biophysical Journal, 102(2), 305-314. https://doi.org/10.1016/j.bpj.2011.12.012
    • Mingels, A. M., Joosen, I. A., Versteylen, M. O., Laufer, E. M., Winkens, M. H., Wildberger, J. E., van Dieijen-Visser, M. P., & Hofstra, L. (2012). High-sensitivity cardiac troponin t: Risk stratification tool in patients with symptoms of chest discomfort. PLOS ONE, 7(4), Article e35059. https://doi.org/10.1371/journal.pone.0035059
    • Prevos, R., Smidt, M. L., Tjan-Heijnen, V. C., van Goethem, M., Beets Tan, R. G., Wildberger, J. E., & Lobbes, M. B. (2012). Pre-treatment differences and early response monitoring of neoadjuvant chemotherapy in breast cancer patients using magnetic resonance imaging: a systematic review. European Radiology, 22(12), 2607-2616. https://doi.org/10.1007/s00330-012-2653-5
    • Joosen, I. A., Schiphof, F., Versteylen, M. O., Laufer, E. M., Winkens, M. H., Nelemans, P. J., Kooman, J. P., Hofstra, L., Wildberger, J. E., & Leiner, T. (2012). Relation between Mild to Moderate Chronic Kidney Disease and Coronary Artery Disease Determined with Coronary CT Angiography. PLOS ONE, 7(10), Article e47267. https://doi.org/10.1371/journal.pone.0047267
    • Maas, M., Lambregts, D. M., Lahaye, M. J., Beets, G. L., Backes, W. H., Vliegen, R. F., Osinga-de Jong, M., Wildberger, J. E., & Beets Tan, R. G. (2012). T-staging of rectal cancer: accuracy of 3.0 Tesla MRI compared with 1.5 Tesla.Abdominal Imaging, 37(3), 475-481. https://doi.org/10.1007/s00261-011-9770-5
    • Rouhl, R. P. W., Mertens, A. E. C. S., van Oostenbrugge, R. J., Damoiseaux, J. G. M. C., Debrus-Palmans, L. L., Henskens, L. H. G., Kroon, A. A., de Leeuw, P. W., Lodder, J., & Tervaert, J. W. C. (2012). Angiogenic T-Cells and Putative Endothelial Progenitor Cells in Hypertension-Related Cerebral Small Vessel Disease. Stroke, 43(1), 256-U509. https://doi.org/10.1161/STROKEAHA.111.632208
    • Kanzler, I., Liehn, E. A., Koenen, R. R., & Weber, C. (2012). Anti-Inflammatory Therapeutic Approaches to Reduce Acute Atherosclerotic Complications. Current Pharmaceutical Biotechnology, 13(1), 37-45. https://doi.org/10.2174/138920112798868557
    • Gommer, E. D., Martens, E. G. H. J., Aalten, P., Shijaku, E., Verhey, F. R. J., Mess, W. H., Ramakers, I. H. G. B., & Reulen, J. P. H. (2012). Dynamic Cerebral Autoregulation in Subjects with Alzheimer's Disease, Mild Cognitive Impairment, and Controls: Evidence for Increased Peripheral Vascular Resistance with Possible Predictive Value. Journal of Alzheimer's Disease, 30(4), 805-813. https://doi.org/10.3233/JAD-2012-111628
    • van der Weg, K., Bekkers, S. C. A. M., Winkens, B., Lemmert, M. E., Schalla, S., Crijns, H. J. G. M., Waltenberger, J., & Gorgels, A. P. M. (2012). Evaluation of the electrocardiogram in identifying and quantifying lateral involvement in nonanterior wall infarction using cardiovascular magnetic resonance imaging. Journal of Electrocardiology, 45(5), 478-484. https://doi.org/10.1016/j.jelectrocard.2012.04.008
    • Loos, C. M. J., van Oostenbrugge, R. J., & Staals, J. (2012). The Appearance of a New White Matter Lesion Adjacent to the Old Infarct in First-Ever Lacunar Stroke Patients: A Two-Year Follow-Up Study with MRI. Cerebrovascular Diseases, 34(5-6), 443-445. https://doi.org/10.1159/000344003
  • 2011
    • Daissormont, I. T. M. N., Christ, A., Temmerman, L., Millares, S. S., Seijkens, T., Manca, M., Rousch, M., Poggi, M., Boon, L., van der Loos, C. M., Daemen, M. J. A. P., Lutgens, E., Halvorsen, B., Aukrust, P., Janssen, E. M., & Biessen, E. A. L. (2011). Plasmacytoid Dendritic Cells Protect Against Atherosclerosis by Tuning T-Cell Proliferation and Activity. Circulation Research, 109(12), 1387-1395. https://doi.org/10.1161/CIRCRESAHA.111.256529
    • Koenen, R. R., & Weber, C. (2011). Chemokines: established and novel targets in atherosclerosis. EMBO Molecular Medicine, 3(12), 713-725. https://doi.org/10.1002/emmm.201100183
    • Butoi, E. D., Gan, A. M., Manduteanu, I., Stan, D., Calin, M., Pirvulescu, M., Koenen, R. R., Weber, C., & Simionescu, M. (2011). Cross talk between smooth muscle cells and monocytes/activated monocytes via CX3CL1/CX3CR1 axis augments expression of pro-atherogenic molecules. Biochimica et Biophysica Acta-Molecular Cell Research, 1813(12), 2026-2035. https://doi.org/10.1016/j.bbamcr.2011.08.009
    • Kuijpers, M. J. E., Megens, R. T. A., Nikookhesal, E., Feijge, M. A. H., De Mey, J. G. R., Egbrink, M. G. A. O., van Giezen, J. J. J., & Heemskerk, J. W. M. (2011). Role of newly formed platelets in thrombus formation in rat after clopidogrel treatment: comparison to the reversible binding P2Y(12) antagonist ticagrelor. Thrombosis and Haemostasis, 106(6), 1179-1188. https://doi.org/10.1160/TH11-04-0252
    • Liehn, E. A., Tuchscheerer, N., Kanzler, I., Drechsler, M., Fraemohs, L., Schuh, A., Koenen, R. R., Zander, S., Soehnlein, O., Hristov, M., Grigorescu, G., Urs, A. O., Leabu, M., Bucur, I., Merx, M. W., Zernecke, A., Ehling, J., Gremse, F., Lammers, T., ... Weber, C. (2011). Double-Edged Role of the CXCL12/CXCR4 Axis in Experimental Myocardial Infarction. Journal of the American College of Cardiology, 58(23), 2415-2423. https://doi.org/10.1016/j.jacc.2011.08.033
    • Weber, C., & Noels, H. (2011). Atherosclerosis: current pathogenesis and therapeutic options. Nature Medicine, 17(11), 1410-1422. https://doi.org/10.1038/nm.2538
    • Engel, D., Beckers, L., Wijnands, E., Seijkens, T., Lievens, D., Drechsler, M., Gerdes, N., Soehnlein, O., Daemen, M. J. A. P., Stan, R. V., Biessen, E. A. L., & Lutgens, E. (2011). Caveolin-1 deficiency decreases atherosclerosis by hampering leukocyte influx into the arterial wall and generating a regulatory T-cell response. Faseb Journal, 25(11), 3838-3848. https://doi.org/10.1096/fj.11-183350
    • Wolfs, I. M. J., Donners, M. M. P. C., & de Winther, M. P. J. (2011). Differentiation factors and cytokines in the atherosclerotic plaque micro-environment as a trigger for macrophage polarisation. Thrombosis and Haemostasis, 106(5), 763-771. https://doi.org/10.1160/TH11-05-0320
    • Reitsma, S., Egbrink, M. G. A. O., Heijnen, V. V. T., Megens, R. T. A., Engels, W., Vink, H., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2011). Endothelial glycocalyx thickness and platelet-vessel wall interactions during atherogenesis. Thrombosis and Haemostasis, 106(5), 939-946. https://doi.org/10.1160/TH11-02-0133
    • Bot, I., & Biessen, E. A. L. (2011). Mast cells in atherosclerosis. Thrombosis and Haemostasis, 106(5), 820-826. https://doi.org/10.1160/TH11-05-0291
    • Laeremans, H., Hackeng, T. M., van Zandvoort, M. A. M. J., Thijssen, V. L. J. L., Janssen, B. J. A., Ottenheijm, H. C. J., Smits, J. F. M., & Blankesteijn, W. M. (2011). Blocking of Frizzled Signaling With a Homologous Peptide Fragment of Wnt3a/Wnt5a Reduces Infarct Expansion and Prevents the Development of Heart Failure After Myocardial Infarction. Circulation, 124(15), 1626-U107. https://doi.org/10.1161/CIRCULATIONAHA.110.976969
    • Landry, G., Granton, P. V., Reniers, B., Ollers, M. C., Beaulieu, L., Wildberger, J. E., & Verhaegen, F. (2011). Simulation study on potential accuracy gains from dual energy CT tissue segmentation for low-energy brachytherapy Monte Carlo dose calculations. Physics in Medicine and Biology, 56(19), 6257-6278. https://doi.org/10.1088/0031-9155/56/19/007
    • Soehnlein, O., Wantha, S., Simsekyilmaz, S., Doering, Y., Megens, R. T. A., Mause, S. F., Drechsler, M., Smeets, R., Weinandy, S., Schreiber, F., Gries, T., Jockenhoevel, S., Moeller, M., Vijayan, S., van Zandvoort, M. A. M. J., Agerberth, B., Pham, C. C. T. N., Gallo, R. L., Hackeng, T. M., ... Weber, C. (2011). Neutrophil-Derived Cathelicidin Protects from Neointimal Hyperplasia. Science Translational Medicine, 3(103), 10. https://doi.org/10.1126/scitranslmed.3002531
    • Hoving, S., Heeneman, S., Gijbels, M. J. J., Poele, J. A. M. T., Pol, J. F. C., Gabriels, K., Russell, N. S., Daernen, M. J. A. P., & Stewart, F. A. (2011). Anti-inflammatory and anti-thrombotic intervention strategies using atorvastatin, clopidogrel and knock-down of CD40L do not modify radiation-induced atherosclerosis in ApoE null mice. Radiotherapy and Oncology, 101(1), 100-108. https://doi.org/10.1016/j.radonc.2011.09.019
    • Poggi, M., Engel, D., Christ, A., Beckers, L., Wijnands, E., Boon, L., Driessen, A., Cleutjens, J., Weber, C., Gerdes, N., & Lutgens, E. (2011). CD40L Deficiency Ameliorates Adipose Tissue Inflammation and Metabolic Manifestations of Obesity in Mice. Arteriosclerosis Thrombosis and Vascular Biology, 31(10), 2251-U248. https://doi.org/10.1161/ATVBAHA.111.231357
    • van Almen, G. C., Verhesen, W., van Leeuwen, R. E. W., van de Vrie, M., Eurlings, C., Schellings, M. W. M., Swinnen, M., Cleutjens, J. P. M., van Zandvoort, M. A. M. J., Heymans, S., & Schroen, B. (2011). MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. Aging Cell, 10(5), 769-779. https://doi.org/10.1111/j.1474-9726.2011.00714.x
    • Weijs, B., Blaauw, Y., Rennenberg, R. J. M. W., Schurgers, L. J., Timmermans, C. C. M. M., Pison, L., Nieuwlaat, R., Hofstra, L., Kroon, A. A., Wildberger, J., & Crijns, H. J. G. M. (2011). Patients using vitamin K antagonists show increased levels of coronary calcification: an observational study in low-risk atrial fibrillation patients. European Heart Journal, 32(20), 2555-2562. https://doi.org/10.1093/eurheartj/ehr226
    • van Almen, G. C., Swinnen, M., Carai, P., Verhesen, W., Cleutjens, J. P. M., D'hooge, J., Verheyen, F. K., Pinto, Y. M., Schroen, B., Carmeliet, P., & Heymans, S. (2011). Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy. Journal of Molecular and Cellular Cardiology, 51(3), 318-328. https://doi.org/10.1016/j.yjmcc.2011.05.010
    • Hoff, E. I., Steinbusch, H. W. M., van Oostenbrugge, R. J., Garrett, L., Otte, W. M., van der Marel, K., & Dijkhuizen, R. M. (2011). Alterations in the cholinergic system after frontal cortical infarction in rat brain: Pharmacological magnetic resonance imaging of muscarinic receptor responsiveness and stereological analysis of cholinergic forebrain neurons. Neurobiology of Disease, 43(3), 625-634. https://doi.org/10.1016/j.nbd.2011.05.011
    • Landry, G., Reniers, B., Granton, P. V., van Rooijen, B. D., Beaulieu, L., Wildberger, J. E., & Verhaegen, F. (2011). Extracting atomic numbers and electron densities from a dual source dual energy CT scanner: Experiments and a simulation model. Radiotherapy and Oncology, 100(3), 375-379. https://doi.org/10.1016/j.radonc.2011.08.029
    • Vasina, E. M., Cauwenberghs, S., Feijge, M. A. H., Heemskerk, J. W. M., Weber, C., & Koenen, R. R. (2011). Microparticles from apoptotic platelets promote resident macrophage differentiation. Cell Death & Disease, 2(9), 10. Article e211. https://doi.org/10.1038/cddis.2011.94
    • Cheng, C., Tempel, D., Den Dekker, W. K., Haasdijk, R. A., Chrifi, I., Bos, F. L., Wagtmans, K., Van De Kamp, E. H. M., Blonden, L. A. J., Biessen, E. A. L., Moll, F. L., Pasterkamp, G., Serruys, P. W., Schulte-Merker, S., & Duckers, H. J. (2011). Ets2 Determines the Inflammatory State of Endothelial Cells in Advanced Atherosclerotic Lesions. Circulation Research, 109(4), 385-395. https://doi.org/10.1161/CIRCRESAHA.111.243444
    • Goossens, P., Vergouwe, M. N., Gijbels, M. J. J., Curfs, D. M. J., van Woezik, J. H. G., Hoeksema, M. A., Xanthouleas, S., Leenen, P. J. M., Rupec, R. A., Hofker, M. H., & de Winther, M. P. J. (2011). Myeloid I kappa B alpha Deficiency Promotes Atherogenesis by Enhancing Leukocyte Recruitment to the Plaques. PLOS ONE, 6(7), 8. https://doi.org/10.1371/journal.pone.0022327
    • Goossens, G. H., Bizzarri, A., Venteclef, N., Essers, Y., Cleutjens, J. P. M., Konings, E., Jocken, J. W., Cajlakovic, M., Ribitsch, V., Clement, K., & Blaak, E. E. (2011). Increased adipose tissue oxygen tension in obese compared with lean men is accompanied by insulin resistance, impaired adipose tissue capillarization, and inflammation. Circulation, 124(1), 67-76. https://doi.org/10.1161/CIRCULATIONAHA.111.027813