Publications
- 2013
- Smid, M., Dielis, A. W. J. H., Spronk, H. M. H., Rumley, A., van Oerle, R., Woodward, M., ten Cate, H., & Lowe, G. (2013). Thrombin Generation in the Glasgow Myocardial Infarction Study. PLOS ONE, 8(6), Article e66977. https://doi.org/10.1371/journal.pone.0066977
- Dijkgraaf, I., Van de Vijver, P., Dirksen, A., & Hackeng, T. M. (2013). Synthesis and application of cNGR-containing imaging agents for detection of angiogenesis. Bioorganic & Medicinal Chemistry, 21(12), 3555-3564. https://doi.org/10.1016/j.bmc.2013.04.002
- Bosch, Y., Al Dieri, R., Ten Cate, H., Nelemans, P., Bloemen, S., Hemker, C., Weerwind, P., Maessen, J., & Mochtar, B. (2013). Preoperative thrombin generation is predictive for the risk of blood loss after cardiac surgery: a research article. Journal of Cardiothoracic Surgery, 8(1). https://doi.org/10.1186/1749-8090-8-154
- Theuwissen, E., Teunissen, K. J., Spronk, H. M. H., Hamulyak, K., Ten Cate, H., Shearer, M. J., Vermeer, C., & Schurgers, L. J. (2013). Effect of low-dose supplements of menaquinone-7 (vitamin K-2) on the stability of oral anticoagulant treatment: dose-response relationship in healthy volunteers. Journal of Thrombosis and Haemostasis, 11(6), 1085-1092. https://doi.org/10.1111/jth.12203
- den Hoed, M., Eijgelsheim, M., Esko, T., Brundel, B. J. J. M., Peal, D. S., Evans, D. M., Nolte, I. M., Segrè, A. V., Holm, H., Handsaker, R. E., Westra, H.-J., Johnson, T., Isaacs, A., Yang, J., Lundby, A., Zhao, J. H., Kim, Y. J., Go, M. J., Almgren, P., ... Loos, R. J. F. (2013). Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics, 45(6), 621-31. https://doi.org/10.1038/ng.2610
- van der Meijden, P. E. J., Bouman, A. C., Feijge, M. A. H., van Oerle, R., Spronk, H. M. H., Hamulyak, K., ten Cate-Hoek, A. J., ten Cate, H., & Heemskerk, J. W. M. (2013). Platelet Dysfunction in Thrombosis Patients Treated with Vitamin K Antagonists and Recurrent Bleeding. PLOS ONE, 8(5). https://doi.org/10.1371/journal.pone.0064112
- Grottke, O., Rossaint, R., Henskens, Y., van Oerle, R., ten Cate, H., & Spronk, H. H. (2013). Thrombin Generation Capacity of Prothrombin Complex Concentrate in an In Vitro Dilutional Model. PLOS ONE, 8(5), Article e64100. https://doi.org/10.1371/journal.pone.0064100
- Mattheij, N. J. A., Gilio, K., van Kruchten, R., Jobe, S. M., Wieschhaus, A. J., Chishti, A. H., Collins, P., Heemskerk, J. W. M., & Cosemans, J. M. E. M. (2013). Dual Mechanism of Integrin alpha(IIb)beta(3) Closure in Procoagulant Platelets. Journal of Biological Chemistry, 288(19), 13325-13336. https://doi.org/10.1074/jbc.M112.428359
- Strak, M., Hoek, G., Steenhof, M., Kilinc, E., Godri, K. J., Gosens, I., Mudway, I. S., van Oerle, R., Spronk, H. M. H., Cassee, F. R., Kelly, F. J., Harrison, R. M., Brunekreef, B., Lebret, E., & Janssen, N. A. H. (2013). Components of ambient air pollution affect thrombin generation in healthy humans: the RAPTES project. Occupational and Environmental Medicine, 70(5), 332-340. https://doi.org/10.1136/oemed-2012-100992
- Raps, M., Rosendaal, F., Ballieux, B., Rosing, J., Thomassen, S., Helmerhorst, F., & Van Vliet, H. (2013). Resistance to APC and SHBG levels during use of a four-phasic oral contraceptive containing dienogest and estradiol valerate: a randomized controlled trial. Journal of Thrombosis and Haemostasis, 11(5), 855-861. https://doi.org/10.1111/jth.12172
- Winckers, K., ten Cate, H., & Hackeng, T. M. (2013). The role of tissue factor pathway inhibitor in atherosclerosis and arterial thrombosis. Blood Reviews, 27(3), 119-132. https://doi.org/10.1016/j.blre.2013.03.001
- CARDIOGRAM, METASTROKE, Keating, B. J., & Asselbergs, F. W. (2013). Loci influencing blood pressure identified using a cardiovascular gene-centric array. Human Molecular Genetics, 22(8), 1663-78. https://doi.org/10.1093/hmg/dds555
- Peraramelli, S., Thomassen, S., Heinzmann, A., Rosing, J., Hackeng, T. M., Hartmann, R., Scheiflinger, F., & Dockal, M. (2013). Direct inhibition of factor VIIa by TFPI and TFPI constructs. Journal of Thrombosis and Haemostasis, 11(4), 704-714. https://doi.org/10.1111/jth.12152
- Fuchs, B., de Witt, S., Solecka, B. A., Kroening, M., Obser, T., Cosemans, J. M. E. M., Schneppenheim, R., Heemskerk, J. W. M., & Kannicht, C. (2013). Distinct Role of von Willebrand Factor Triplet Bands in Glycoprotein Ib-Dependent Platelet Adhesion and Thrombus Formation under Flow. Seminars in Thrombosis and Hemostasis, 39(3), 306-314. https://doi.org/10.1055/s-0032-1328971
- Seehase, M., Houthuizen, P., Jellema, R. K., Collins, J. J., Bekers, O., Breuer, J., & Kramer, B. W. (2013). Propofol administration to the fetal-maternal unit reduces cardiac injury in late-preterm lambs subjected to severe prenatal asphyxia and cardiac arrest. Pediatric Research, 73(4), 427-434. https://doi.org/10.1038/pr.2013.10
- Strak, M., Hoek, G., Godri, K. J., Gosens, I., Mudway, I. S., van Oerle, R., Spronk, H. M. H., Cassee, F. R., Lebret, E., Kelly, F. J., Harrison, R. M., Brunekreef, B., Steenhof, M., & Janssen, N. A. H. (2013). Composition of PM Affects Acute Vascular Inflammatory and Coagulative Markers - The RAPTES Project. PLOS ONE, 8(3), Article e58944. https://doi.org/10.1371/journal.pone.0058944
- van Bussel, B. C. T., Ferreira, I., van de Waarenburg, M. P., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Henry, R. M., Feskens, E. J., Stehouwer, C. D. A., & Schalkwijk, C. G. (2013). Multiple inflammatory biomarker detection in a prospective cohort study: a cross-validation between well-established single-biomarker techniques and an electrochemiluminescense-based multi-array platform.PLOS ONE, 8(3), Article 58576. https://doi.org/10.1371/journal.pone.0058576
- Wantha, S., Alard, J.-E., Megens, R. T. A., van der Does, A. M., Doering, Y., Drechsler, M., Pham, C. T. N., Wang, M.-W., Wang, J.-M., Gallo, R. L., von Hundelshausen, P., Lindbom, L., Hackeng, T., Weber, C., & Soehnlein, O. (2013). Neutrophil-Derived Cathelicidin Promotes Adhesion of Classical Monocytes. Circulation Research, 112(5), 792-801. https://doi.org/10.1161/CIRCRESAHA.112.300666
- van der Kolk, J. H., Boelens, R., Halkes, S. B. A., Wijnberg, I. D., de Sain-van der Velden, M. G. M., & Ippel, J. H. (2013). Some notes on fatal acquired multiple acyl-CoA dehydrogenase deficiency (MADD) in a two-year-old warmblood stallion and European tar spot (Rhytisma acerinum). Veterinary Quarterly, 33(1), 51-55. https://doi.org/10.1080/01652176.2012.758904
- Soehnlein, O., Drechsler, M., Doering, Y., Lievens, D., Hartwig, H., Kemmerich, K., Ortega-Gomez, A., Mandl, M., Vijayan, S., Projahn, D., Garlichs, C. D., Koenen, R. R., Hristov, M., Lutgens, E., Zernecke, A., & Weber, C. (2013). Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes. EMBO Molecular Medicine, 5(3), 471-481. https://doi.org/10.1002/emmm.201201717
- Demirkan, A., Isaacs, A., Ugocsai, P., Liebisch, G., Struchalin, M., Rudan, I., Wilson, J. F., Pramstaller, P. P., Gyllensten, U., Campbell, H., Schmitz, G., Oostra, B. A., & van Duijn, C. M. (2013). Plasma phosphatidylcholine and sphingomyelin concentrations are associated with depression and anxiety symptoms in a Dutch family-based lipidomics study. Journal of Psychiatric Research, 47(3), 357-62. https://doi.org/10.1016/j.jpsychires.2012.11.001
- Ten Cate-Hoek, A. J., Prins, M. H., Wittens, C. H. A., & Cate, H. T. (2013). Postintervention duration of anticoagulation in venous surgery. Phlebology: The Journal of Venous Disease, 28(1_suppl), 105-111. https://doi.org/10.1177/0268355513476415
- Kumar, N., Ippel, H., Weber, C., Hackeng, T., & Mayo, K. H. (2013). Protein lysine-N zeta alkylation and O-phosphorylation mediated by DTT-generated reactive oxygen species. Protein Science, 22(3), 327-346. https://doi.org/10.1002/pro.2214
- Borissoff, J. I., Otten, J. J. T., Heeneman, S., Leenders, P., van Oerle, R., Soehnlein, O., Loubele, S. T. B. G., Hamulyak, K., Hackeng, T. M., Daemen, M. J. A. P., Degen, J. L., Weiler, H., Esmon, C. T., van Ryn, J., Biessen, E. A. L., Spronk, H. M. H., & ten Cate, H. (2013). Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice Determine Atherosclerosis Severity and Atherothrombosis Onset in a Neutrophil-Dependent Manner. PLOS ONE, 8(2), Article e55784. https://doi.org/10.1371/journal.pone.0055784
- Esser, D., Oosterink, E., 't Roodt, J. O., Henry, R. M. A., Stehouwer, C. D. A., Muller, M., & Afman, L. A. (2013). Vascular and Inflammatory High Fat Meal Responses in Young Healthy Men; A Discriminative Role of IL-8 Observed in a Randomized Trial. PLOS ONE, 8(2), Article e53474. https://doi.org/10.1371/journal.pone.0053474
- Wijnen, P. A. H. M., Verschakelen, J. A., Bast, A., Bekers, O., & Drent, M. (2013). Diffuse alveolar hemorrhage in coumarin users: a fibrosing interstitial pneumonia trigger?Lung, 191(1), 53-59. https://doi.org/10.1007/s00408-012-9436-2
- Bos, D., Ikram, M. A., Isaacs, A., Verhaaren, B. F. J., Hofman, A., van Duijn, C. M., Witteman, J. C. M., van der Lugt, A., & Vernooij, M. W. (2013). Genetic loci for coronary calcification and serum lipids relate to aortic and carotid calcification. Circulation : Cardiovascular Genetics, 6(1), 47-53. https://doi.org/10.1161/CIRCGENETICS.112.963934
- Köttgen, A., Albrecht, E., Teumer, A., Vitart, V., Krumsiek, J., Hundertmark, C., Pistis, G., Ruggiero, D., O'Seaghdha, C. M., Haller, T., Yang, Q., Tanaka, T., Johnson, A. D., Kutalik, Z., Smith, A. V., Shi, J., Struchalin, M., Middelberg, R. P. S., Brown, M. J., ... LifeLines Cohort Study (2013). Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nature Genetics, 45(2), 145-54. https://doi.org/10.1038/ng.2500
- Rademakers, T., Douma, K., Hackeng, T. M., Post, M. J., Sluimer, J. C., Daemen, M. J. A. P., Biessen, E. A. L., Heeneman, S., & van Zandvoort, M. A. M. J. (2013). Plaque-Associated Vasa Vasorum in Aged Apolipoprotein E-Deficient Mice Exhibit Proatherogenic Functional Features In Vivo. Arteriosclerosis Thrombosis and Vascular Biology, 33(2), 249–256. https://doi.org/10.1161/ATVBAHA.112.300087
- Westein, E., van der Meer, A. D., Kuijpers, M. J. E., Frimat, J.-P., van den Berg, A., & Heemskerk, J. W. M. (2013). Atherosclerotic geometries exacerbate pathological thrombus formation poststenosis in a von Willebrand factor-dependent manner. Proceedings of the National Academy of Sciences of the United States of America, 110(4), 1357-1362. https://doi.org/10.1073/pnas.1209905110
- van de Laar, R. J. J., Stehouwer, C. D. A., van Bussel, B. C. T., Prins, M. H., Twisk, J. W., & Ferreira, I. (2013). Adherence to a Mediterranean dietary pattern in early life is associated with lower arterial stiffness in adulthood: the Amsterdam Growth and Health Longitudinal Study.Journal of Internal Medicine, 273(1), 79-93. https://doi.org/10.1111/j.1365-2796.2012.02577.x
- Nergiz-Unal, R., Kuijpers, M. J. E., de Witt, S. M., Heeneman, S., Feijge, M. A. H., Garcia Caraballo, S., Biessen, E. A., Haenen, G. R. M. M., Cosemans, J. M., & Heemskerk, J. W. (2013). Atheroprotective effect of dietary walnut intake in ApoE-deficient mice: Involvement of lipids and coagulation factors.Thrombosis Research, 131(5), 411-417. https://doi.org/10.1016/j.thromres.2013.01.003
- Wolters, M., Mohades, S. G., Hackeng, T. M., Post, M. J., Kooi, M. E., & Backes, W. H. (2013). Clinical perspectives of hybrid proton-fluorine magnetic resonance imaging and spectroscopy.Investigative Radiology, 48(5), 341-350. https://doi.org/10.1097/RLI.0b013e318277528c
- Wolters, M., van Hoof, R. H., Wagenaar, A., Douma, K., van Zandvoort, M. A., Hackeng, T. M., Post, M. J., Backes, W. H., & Kooi, M. E. (2013). MRI artifacts in the ferric chloride thrombus animal model: an alternative solution: preventing MRI artifacts after thrombus induction with a non-ferromagnetic Lewis acid. Journal of Thrombosis and Haemostasis, 11(9), 1766-1769. https://doi.org/10.1111/jth.12340
- Baumgartner, S., Mensink, R. P., den Hartog, G. J., Bast, A., Bekers, O., Husche, C., Lutjohann, D., & Plat, J. (2013). Oxyphytosterol formation in humans: Identification of high vs. low oxidizers.Biochemical Pharmacology, 86(1), 19-25. https://doi.org/10.1016/j.bcp.2013.02.035
- Smulders, M. W., Kietselaer, B. L. J. H., Das, M., Wildberger, J. E., Crijns, H. J. G. M., Veenstra, L., Brunner La Rocca, H. P., van Dieijen-Visser, M. P., Mingels, A. M. A., Dagnelie, P. C., Post, M. J., Gorgels, A. P. M., van Asselt, A. D. I., Vogel, G., Schalla, S., Kim, R. J., & Bekkers, S. C. A. M. (2013). The role of cardiovascular magnetic resonance imaging and computed tomography angiography in suspected non-ST-elevation myocardial infarction patients: Design and rationale of the CARdiovascular Magnetic rEsoNance imaging and computed Tomography Angiography (CARMENTA) trial. American Heart Journal, 166(6), 968-975. https://doi.org/10.1016/j.ahj.2013.09.012
- Knapen, L. M., Dittrich, S. T., de Vries, F., Starup-Linde, J., Vestergaard, P., Henry, R. M. A., Stolk, L. M., Neef, C. K., & Bazelier, M. T. (2013). Use of biguanides and the risk of colorectal cancer: a register-based cohort study. Current Drug Safety, 8(5), 349-356. https://doi.org/10.2174/15680266113136660068
- Horikoshi, M., Yaghootkar, H., Mook-Kanamori, D. O., Sovio, U., Taal, H. R., Hennig, B. J., Bradfield, J. P., St Pourcain, B., Evans, D. M., Charoen, P., Kaakinen, M., Cousminer, D. L., Lehtimäki, T., Kreiner-Møller, E., Warrington, N. M., Bustamante, M., Feenstra, B., Berry, D. J., Thiering, E., ... Freathy, R. (2013). New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nature Genetics, 45(1), 76-82. https://doi.org/10.1038/ng.2477
- Heemskerk, J. W. M., Mattheij, N. J. A., & Cosemans, J. M. E. M. (2013). Platelet-based coagulation: different populations, different functions. Journal of Thrombosis and Haemostasis, 11(1), 2-16. https://doi.org/10.1111/jth.12045
- Prinzen, L., Staal, H. M., Rouwette, S. J. M., Beckers, E. A. M., ten Broeke, R. H. M., van Rhijn, L. W., & Henskens, Y. M. C. (2013). Triple Red Blood Cell Alloantibody Formation After Bone-Allograft Transplantation. American Journal of Transplantation, 13(1), 229-231. https://doi.org/10.1111/j.1600-6143.2012.04300.x
- Vasina, E. M., Cauwenberghs, S., Staudt, M., Feijge, M. A., Weber, C., Koenen, R. R., & Heemskerk, J. W. (2013). Aging- and activation-induced platelet microparticles suppress apoptosis in monocytic cells and differentially signal to proinflammatory mediator release. American Journal of Blood Research, 3(2), 107-23. https://pubmed.ncbi.nlm.nih.gov/23675563/
- Tijink, M., Janssen, J., Timmer, M., Austen, J., Aldenhoff, Y., Kooman, J., Koole, L., Damoiseaux, J., van Oerle, R., Henskens, Y., & Stamatialis, D. (2013). Development of novel membranes for blood purification therapies based on copolymers of N-vinylpyrrolidone and n-butylmethacrylate. Journal of Materials Chemistry. B, Materials for Biology and Medicine, 1(44), 6066-6077. https://doi.org/10.1039/c3tb20964d
- Lance, M. D., Henskens, Y., Nelemans, P., Theunissen, M. H. S., Van Oerle, R., Spronk, H. M., & Marcus, M. A. E. (2013). Do blood collection methods influence whole-blood platelet function analysis?Platelets, 24(4), 275-281. https://doi.org/10.3109/09537104.2012.689038
- van der Loos, M. J. H. M., Rietveld, C. A., Eklund, N., Koellinger, P. D., Rivadeneira, F., Abecasis, G. R., Ankra-Badu, G. A., Baumeister, S. E., Benjamin, D. J., Biffar, R., Blankenberg, S., Boomsma, D. I., Cesarini, D., Cucca, F., de Geus, E. J. C., Dedoussis, G., Deloukas, P., Dimitriou, M., Eiriksdottir, G., ... Thurik, A. R. (2013). The molecular genetic architecture of self-employment. PLOS ONE, 8(4), e60542. https://doi.org/10.1371/journal.pone.0060542
- Fall, T., Hägg, S., Mägi, R., Ploner, A., Fischer, K., Horikoshi, M., Sarin, A.-P., Thorleifsson, G., Ladenvall, C., Kals, M., Kuningas, M., Draisma, H. H. M., Ried, J. S., van Zuydam, N. R., Huikari, V., Mangino, M., Sonestedt, E., Benyamin, B., Nelson, C. P., ... European Network for Genetic and Genomic Epidemiology (ENGAGE) consortium (2013). The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis. PLOS Medicine , 10(6), e1001474. https://doi.org/10.1371/journal.pmed.1001474
- 2012
- Chasman, D. I., Fuchsberger, C., Pattaro, C., Teumer, A., Böger, C. A., Endlich, K., Olden, M., Chen, M.-H., Tin, A., Taliun, D., Li, M., Gao, X., Gorski, M., Yang, Q., Hundertmark, C., Foster, M. C., O'Seaghdha, C. M., Glazer, N., Isaacs, A., ... CARDIoGRAM Consortium (2012). Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Human Molecular Genetics, 21(24), 5329-43. https://doi.org/10.1093/hmg/dds369
- Borissoff, J. I., Joosen, I. A., Versteylen, M. O., Spronk, H. M., ten Cate, H., & Hofstra, L. (2012). Accelerated In Vivo Thrombin Formation Independently Predicts the Presence and Severity of CT Angiographic Coronary Atherosclerosis. JACC-Cardiovascular Imaging, 5(12), 1201-1210. https://doi.org/10.1016/j.jcmg.2012.01.023
- Dargaud, Y., Wolberg, A. S., Luddington, R., Regnault, V., Spronk, H., Baglin, T., Lecompte, T., Ten Cate, H., & Negrier, C. (2012). Evaluation of a standardized protocol for thrombin generation measurement using the calibrated automated thrombogram: An international multicentre study. Thrombosis Research, 130(6), 929-934. https://doi.org/10.1016/j.thromres.2012.07.017
- Ibrahim-Verbaas, C. A., Zorkoltseva, I. V., Amin, N., Schuur, M., Coppus, A. M. W., Isaacs, A., Aulchenko, Y. S., Breteler, M. M. B., Ikram, M. A., Axenovich, T. I., Verbeek, M. M., van Swieten, J. C., Oostra, B. A., & van Duijn, C. M. (2012). Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates Aβ-40 levels to presenilin 2. Human Genetics, 131(12), 1869-76. https://doi.org/10.1007/s00439-012-1210-2
- Projahn, D., & Koenen, R. R. (2012). Platelets: key players in vascular inflammation. Journal of Leukocyte Biology, 92(6), 1167-1175. https://doi.org/10.1189/jlb.0312151