Loeffen, R., Kleinegris, M. .-C. F., Loubele, S. T. B. G., Pluijmen, P. H. M., Fens, D., van Oerle, R., ten Cate, H., & Spronk, H. M. H. (2012). Preanalytic variables of thrombin generation: towards a standard procedure and validation of the method. Journal of Thrombosis and Haemostasis, 10(12), 2544-2554. https://doi.org/10.1111/jth.12012

Kroon, M. H., Diamant, M., Van Den Hurk, K., Boomsma, F., Alssema, M., Nijpels, G., Kamp, O., Paulus, W. J., Stehouwer, C. D. A., Dekker, J. M., & Henry, R. M. A. (2012). Prospective Associations of B-Type Natriuretic Peptide With Markers of Left Ventricular Function in Individuals With and Without Type 2 Diabetes An 8-year follow-up of the Hoorn Study. Diabetes Care, 35(12), 2510-2514. https://doi.org/10.2337/dc11-1959

Van de Vijver, P., Schmitt, M., Suylen, D., Scheer, L., Thomassen, M. C. L. G. D., Schurgers, L. J., Griffin, J. H., Koenen, R. R., & Hackeng, T. M. (2012). Incorporation of Disulfide Containing Protein Modules into Multivalent Antigenic Conjugates: Generation of Antibodies against the Thrombin-Sensitive Region of Murine Protein S. Journal of the American Chemical Society, 134(47), 19318-19321. https://doi.org/10.1021/ja306993t

Geenen, I. L., Post, M. J., Molin, D. G. M., Schurink, G. W. H., Maessen, J. G., van Oerle, R., ten Cate, H., & Spronk, H. M. H. (2012). Coagulation on endothelial cells: the underexposed part of Virchow's Triad. Thrombosis and Haemostasis, 108(5), 863-871. https://doi.org/10.1160/TH12-04-0269

Amin, N., Byrne, E., Johnson, J., Chenevix-Trench, G., Walter, S., Nolte, I. M., Vink, J. M., Rawal, R., Mangino, M., Teumer, A., Keers, J. C., Verwoert, G., Baumeister, S., Biffar, R., Petersmann, A., Dahmen, N., Doering, A., Isaacs, A., Broer, L., ... van Duijn, C. M. (2012). Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM. Molecular Psychiatry, 17(11), 1116-29. https://doi.org/10.1038/mp.2011.101

Nazari-Jahantigh, M., Wei, Y., Noels, H., Akhtar, S., Zhou, Z., Koenen, R. R., Heyll, K., Gremse, F., Kiessling, F., Grommes, J., Weber, C., & Schober, A. (2012). MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. Journal of Clinical Investigation, 122(11), 4190-4202. https://doi.org/10.1172/JCI61716

Willemsen, S., Hartog, J. W. L., van Veldhuisen, D. J., van der Meer, P., Roze, J. F., Jaarsma, T., Schalkwijk, C., van der Horst, I. C. C., Hillege, H. L., & Voors, A. A. (2012). The role of advanced glycation end-products and their receptor on outcome in heart failure patients with preserved and reduced ejection fraction. American Heart Journal, 164(5), 742-U146. https://doi.org/10.1016/j.ahj.2012.07.027

Compeer, M. G., Suylen, D. P. L., Hackeng, T. M., & De Mey, J. G. R. (2012). Endothelin-1 and-2: Two amino acids matter. Life Sciences, 91(13-14), 607-612. https://doi.org/10.1016/j.lfs.2012.02.011

Yang, J., Loos, R. J. F., Powell, J. E., Medland, S. E., Speliotes, E. K., Chasman, D. I., Rose, L. M., Thorleifsson, G., Steinthorsdottir, V., Maegi, R., Waite, L. L., Smith, A. V., Yerges-Armstrong, L. M., Monda, K. L., Hadley, D., Mahajan, A., Li, G., Kapur, K., Vitart, V., ... Visscher, P. M. (2012). FTO genotype is associated with phenotypic variability of body mass index. Nature, 490(7419), 267–272. https://doi.org/10.1038/nature11401

Geersing, G.-J., Erkens, P. M. G., Lucassen, W. A. M., Buller, H. R., ten Cate, H., Hoes, A. W., Moons, K. G. M., Prins, M. H., Oudega, R., van Weert, H. C. P. M., & Stoffers, H. E. J. H. (2012). Safe exclusion of pulmonary embolism using the Wells rule and qualitative D-dimer testing in primary care: prospective cohort study. BMJ, 345(7880), Article e6564. https://doi.org/10.1136/bmj.e6564

Amin, N., Schuur, M., Gusareva, E. S., Isaacs, A., Aulchenko, Y. S., Kirichenko, A. V., Zorkoltseva, I. V., Axenovich, T. I., Oostra, B. A., Janssens, A. C. J. W., & van Duijn, C. M. (2012). A genome-wide linkage study of individuals with high scores on NEO personality traits. Molecular Psychiatry, 17(10), 1031-41. https://doi.org/10.1038/mp.2011.97

Talens, S., Malfliet, J. J. M. C., Rudez, G., Spronk, H. M. H., Janssen, N. A. H., Meijer, P., Kluft, C., de Maat, M. P. M., & Rijken, D. C. (2012). Biological variation in tPA-induced plasma clot lysis time. Thrombosis and Haemostasis, 108(4), 640-646. https://doi.org/10.1160/TH12-02-0124

van der Meijden, P. E. J., Feijge, M. A. H., Swieringa, F., Gilio, K., Nergiz-Unal, R., Hamulyak, K., & Heemskerk, J. W. M. (2012). Key role of integrin alpha(IIb)beta(3) signaling to Syk kinase in tissue factor-induced thrombin generation. Cellular and Molecular Life Sciences, 69(20), 3481-3492. https://doi.org/10.1007/s00018-012-1033-2

Erkens, P. M. G., ten Cate, H., Buller, H. R., & Prins, M. H. (2012). Benchmark for Time in Therapeutic Range in Venous Thromboembolism: A Systematic Review and Meta-Analysis. PLOS ONE, 7(9), Article e42269. https://doi.org/10.1371/journal.pone.0042269

Scott, R. A., Lagou, V., Welch, R. P., Wheeler, E., Montasser, M. E., Luan, J., Mägi, R., Strawbridge, R. J., Rehnberg, E., Gustafsson, S., Kanoni, S., Rasmussen-Torvik, L. J., Yengo, L., Lecoeur, C., Shungin, D., Sanna, S., Sidore, C., Johnson, P. C. D., Jukema, J. W., ... Barroso, I. (2012). Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nature Genetics, 44(9), 991-1005. https://doi.org/10.1038/ng.2385

Lance, M. D., Kuiper, G. J. A. J. M., Sloep, M., Spronk, H. M. H., van Oerle, R., ten Cate, H., Marcus, M. A. E., & Henskens, Y. M. C. (2012). The effects of pneumatic tube system transport on ROTEM analysis and contact activation assessed by thrombin generation test. Thrombosis Research, 130(3), E147-E150. https://doi.org/10.1016/j.thromres.2012.05.002

Mingels, A. M., Cobbaert, C. M., de Jong, N., van den Hof, W. F., & van Dieijen-Visser, M. P. (2012). Time- and temperature-dependent stability of troponin standard reference material 2921 in serum and plasma. Clinical Chemistry and Laboratory Medicine, 50(9), 1681-1684. https://doi.org/10.1515/cclm-2011-1851

Marchetti, M., Diani, E., ten Cate, H., & Falanga, A. (2012). Characterization of the thrombin generation potential of leukemic and solid tumor cells by calibrated automated thrombography. Haematologica-the Hematology Journal, 97(8), 1173-1180. https://doi.org/10.3324/haematol.2011.055343

Bouman, A. C., Smits, J., Ten Cate, H., & Ten Cate-Hoek, A. J. (2012). Markers of coagulation, fibrinolysis and inflammation in relation to post-thrombotic syndrome. Journal of Thrombosis and Haemostasis, 10(8), 1532-1538. https://doi.org/10.1111/j.1538-7836.2012.04798.x

Peraramelli, S., Suylen, D. P. L., Rosing, J., & Hackeng, T. M. (2012). The Kunitz 1 and Kunitz 3 domains of tissue factor pathway inhibitor are required for efficient inhibition of factor Xa. Thrombosis and Haemostasis, 108(2), 266-276. https://doi.org/10.1160/TH11-12-0902

Durik, M., Kavousi, M., van der Pluijm, I., Isaacs, A., Cheng, C., Verdonk, K., Loot, A. E., Oeseburg, H., Bhaggoe, U. M., Leijten, F., van Veghel, R., de Vries, R., Rudez, G., Brandt, R., Ridwan, Y. R., van Deel, E. D., de Boer, M., Tempel, D., Fleming, I., ... Roks, A. J. M. (2012). Nucleotide excision DNA repair is associated with age-related vascular dysfunction. Circulation, 126(4), 468-78. https://doi.org/10.1161/CIRCULATIONAHA.112.104380

Compeer, M. G., Meens, M. J. P. M. T., Hackeng, T. M., Neugebauer, W. A., Hoeltke, C., & De Mey, J. G. R. (2012). Agonist-dependent modulation of arterial endothelinA receptor function. British Journal of Pharmacology, 166(6), 1833-1845. https://doi.org/10.1111/j.1476-5381.2012.01896.x

van Kruchten, R., Braun, A., Feijge, M. A. H., Kuijpers, M. J. E., Rivera-Galdos, R., Kraft, P., Stoll, G., Kleinschnitz, C., Bevers, E. M., Nieswandt, B., & Heemskerk, J. W. M. (2012). Antithrombotic Potential of Blockers of Store-Operated Calcium Channels in Platelets. Arteriosclerosis Thrombosis and Vascular Biology, 32(7), 1717-1723. https://doi.org/10.1161/ATVBAHA.111.243907

van Gerven, P. W. M., van Boxtel, M. P. J., Ausems, E. E. B., Bekers, O., & Jolles, J. (2012). Do apolipoprotein E genotype and educational attainment predict the rate of cognitive decline in normal aging? A 12-year follow-up of the Maastricht Aging Study. Neuropsychology, 26(4), 459-472. https://doi.org/10.1037/a0028685

Doering, Y., Soehnlein, O., Drechsler, M., Shagdarsuren, E., Chaudhari, S. M., Meiler, S., Hartwig, H., Hristov, M., Koenen, R. R., Hieronymus, T., Zenke, M., Weber, C., & Zernecke, A. (2012). Hematopoietic Interferon Regulatory Factor 8-Deficiency Accelerates Atherosclerosis in Mice. Arteriosclerosis Thrombosis and Vascular Biology, 32(7), 1613-1623. https://doi.org/10.1161/ATVBAHA.111.236539

van de Laar, R. J. J., Stehouwer, C. D. A., van Bussel, B. C. T., te Velde, S. J., Prins, M. H., Twisk, J. W., & Ferreira, I. (2012). Lower lifetime dietary fiber intake is associated with carotid artery stiffness: the Amsterdam Growth and Health Longitudinal Study. American Journal of Clinical Nutrition, 96(1), 14-23. https://doi.org/10.3945/ajcn.111.024703

Nur, E., Brandjes, D. P., Teerlink, T., Otten, H.-M., Elferink, R. P. J. O., Muskiet, F., Evers, L. M., ten Cate, H., Biemond, B. J., Duits, A. J., & Schnog, J.-J. B. (2012). N-acetylcysteine reduces oxidative stress in sickle cell patients. Annals of Hematology, 91(7), 1097-1105. https://doi.org/10.1007/s00277-011-1404-z

de Lange, N. M., Lance, M. D., de Groot, R., Beckers, E. A. M., Henskens, Y. M., & Scheepers, H. C. J. (2012). Obstetric Hemorrhage and Coagulation: An Update. Thromboelastography, Thromboelastometry, and Conventional Coagulation Tests in the Diagnosis and Prediction of Postpartum Hemorrhage. Obstetrical & Gynecological Survey, 67(7), 426-435. https://doi.org/10.1097/OGX.0b013e3182605861

Lance, M. D., Ninivaggi, M., Schols, S. E. M., Feijge, M. A. H., Oehrl, S. K., Kuiper, G. J. A. J. M., Nikiforou, M., Marcus, M. A. E., Hamulyak, K., van Pampus, E. C. M., ten Cate, H., & Heemskerk, J. W. M. (2012). Perioperative dilutional coagulopathy treated with fresh frozen plasma and fibrinogen concentrate: a prospective randomized intervention trial. Vox Sanguinis, 103(1), 25-34. https://doi.org/10.1111/j.1423-0410.2011.01575.x

van der Meijden, P. E. J., van Schilfgaarde, M., van Oerle, R., Renne, T., ten Cate, H., & Spronk, H. M. H. (2012). Platelet- and erythrocyte-derived microparticles trigger thrombin generation via factor XIIa. Journal of Thrombosis and Haemostasis, 10(7), 1355-1362. https://doi.org/10.1111/j.1538-7836.2012.04758.x

Lance, M. D., Marcus, M. A. E., van Oerle, R., Theunissen, H. M. S., & Henskens, Y. M. C. (2012). Platelet concentrate transport in pneumatic tube systems - does it work?Vox Sanguinis, 103(1), 79-82. https://doi.org/10.1111/j.1423-0410.2011.01580.x

Loeffen, R., Spronk, H. M. H., & ten Cate, H. (2012). The impact of blood coagulability on atherosclerosis and cardiovascular disease. Journal of Thrombosis and Haemostasis, 10(7), 1207-1216. https://doi.org/10.1111/j.1538-7836.2012.04782.x

Chatrou, M. L. L., Winckers, K., Hackeng, T. M., Reutelingsperger, C. P. M., & Schurgers, L. J. (2012). Vascular calcification: The price to pay for anticoagulation therapy with vitamin K-antagonists. Blood Reviews, 26(4), 155-166. https://doi.org/10.1016/j.blre.2012.03.002

Klinkenberg, L. J., Res, P. T., van Loon, L. J. C., van Dieijen-Visser, M. P., & Meex, S. J. R. (2012). Strong link between basal and exercise-induced cardiac troponin T levels: Do both reflect risk?International Journal of Cardiology, 158(1), 129-131. https://doi.org/10.1016/j.ijcard.2012.04.050

Sanders, M. P. A., Barbosa, A. J. M., Zarzycka, B., Nicolaes, G. A. F., Klomp, J. P. G., de Vlieg, J., & Del Rio, A. (2012). Comparative Analysis of Pharmacophore Screening Tools. Journal of Chemical Information and Modeling, 52(6), 1607-1620. https://doi.org/10.1021/ci2005274

Hanssen, S. J. P., van de Poll, M. C. G., Houben, A. J., Vermeulen Windsant, I. C., Snoeijs, M. G., Bekers, O., Buurman, W. A., & Jacobs, M. J. H. M. (2012). Hemolysis compromises nitric oxide-dependent vasodilatory responses in patients undergoing major cardiovascular surgery.Thoracic and Cardiovascular Surgeon, 60(4), 255-261. https://doi.org/10.1055/s-0031-1299571

van den Hurk, K., Alssema, M., Kamp, O., Henry, R. M., Stehouwer, C. D., Smulders, Y. M., Nijpels, G., Paulus, W. J., & Dekker, J. M. (2012). Independent Associations of Glucose Status and Arterial Stiffness With Left Ventricular Diastolic Dysfunction An 8-year follow-up of the Hoorn Study. Diabetes Care, 35(6), 1258-1264. https://doi.org/10.2337/dc11-1336

Raps, M., Helmerhorst, F., Fleischer, K., Thomassen, S., Rosendaal, F., Rosing, J., Ballieux, B., & Van Vliet, H. (2012). Sex hormone-binding globulin as a marker for the thrombotic risk of hormonal contraceptives. Journal of Thrombosis and Haemostasis, 10(6), 992-997. https://doi.org/10.1111/j.1538-7836.2012.04720.x

Cardinaels, E. P., Mingels, A. M., Jacobs, L. H., Meex, S. J., Bekers, O., & van Dieijen-Visser, M. P. (2012). A comprehensive review of upper reference limits reported for (high-)sensitivity cardiac troponin assays: The challenges that lie ahead. Clinical Chemistry and Laboratory Medicine, 50(5), 791-806. https://doi.org/10.1515/cclm-2011-0895

Postea, O., Vasina, E. M., Cauwenberghs, S., Projahn, D., Liehn, E. A., Lievens, D., Theelen, W., Kramp, B. K., Butoi, E. D., Soehnlein, O., Heemskerk, J. W. M., Ludwig, A., Weber, C., & Koenen, R. R. (2012). Contribution of Platelet CX(3)CR1 to Platelet-Monocyte Complex Formation and Vascular Recruitment During Hyperlipidemia. Arteriosclerosis Thrombosis and Vascular Biology, 32(5), 1186-1193. https://doi.org/10.1161/ATVBAHA.111.243485

Beijers, H. J. B. H., Ferreira, I., Spronk, H. M. H., Bravenboer, B., Dekker, J. M., Nijpels, G., ten Cate, H., & Stehouwer, C. D. A. (2012). Impaired glucose metabolism and type 2 diabetes are associated with hypercoagulability: potential role of central adiposity and low-grade inflammation - The Hoorn Study. Thrombosis Research, 129(5), 557-562. https://doi.org/10.1016/j.thromres.2011.07.033

Peraramelli, S., Rosing, J., & Hackeng, T. M. (2012). TFPI-dependent activities of Protein S. Thrombosis Research, 129(SUPPL. 2), S23-S26. https://doi.org/10.1016/j.thromres.2012.02.024

ten Cate, H. (2012). Tissue factor-driven thrombin generation and inflammation in atherosclerosis. Thrombosis Research, 129(SUPPL. 2), S38-S40. https://doi.org/10.1016/j.thromres.2012.02.028

Mencarelli, C., Bode, G. H., Losen, M., Kulharia, M., Molenaar, P. C., Veerhuis, R., Steinbusch, H. W. M., De Baets, M. H., Nicolaes, G. A. F., & Martinez-Martinez, P. (2012). Goodpasture Antigen-binding Protein/Ceramide Transporter Binds to Human Serum Amyloid P-Component and Is Present in Brain Amyloid Plaques. Journal of Biological Chemistry, 287(18), 14897-14911. https://doi.org/10.1074/jbc.M111.299545

Doering, Y., Manthey, H. D., Drechsler, M., Lievens, D., Megens, R. T. A., Soehnlein, O., Busch, M., Manca, M., Koenen, R. R., Pelisek, J., Daemen, M. J., Lutgens, E., Zenke, M., Binder, C. J., Weber, C., & Zernecke, A. (2012). Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis. Circulation, 125(13), 1673-U190. https://doi.org/10.1161/CIRCULATIONAHA.111.046755

Trappenburg, M. C., van Schilfgaarde, M., Frerichs, F. C. P., Spronk, H. M. H., ten Cate, H., de Fijter, C. W. H., Terpstra, W. E., & Leyte, A. (2012). Chronic renal failure is accompanied by endothelial activation and a large increase in microparticle numbers with reduced procoagulant capacity. Nephrology Dialysis Transplantation, 27(4), 1446-1453. https://doi.org/10.1093/ndt/gfr474

ten Cate-Hoek, A. J., van der Velde, E. F., Toll, D. B., van Weert, H. C. P. M., Moons, K. G. M., Buller, H. R., Hoes, A. W., Joore, M. A., Oudega, R., Prins, M. H., & Stoffers, H. E. J. H. (2012). Common alternative diagnoses in general practice when deep venous thrombosis is excluded. Netherlands Journal of Medicine, 70(3), 130-135.

Grommes, J., Alard, J.-E., Drechsler, M., Wantha, S., Morgelin, M., Kuebler, W. M., Jacobs, M., von Hundelshausen, P., Markart, P., Wygrecka, M., Preissner, K. T., Hackeng, T. M., Koenen, R. R., Weber, C., & Soehnlein, O. (2012). Disruption of Platelet-derived Chemokine Heteromers Prevents Neutrophil Extravasation in Acute Lung Injury. American Journal of Respiratory and Critical Care Medicine, 185(6), 628-636. https://doi.org/10.1164/rccm.201108-1533OC

Lecut, C., Faccinetto, C., Delierneux, C., Van Oerle, R., Spronk, H. M. H., Evans, R. J., El Benna, J., Bours, V., & Oury, C. (2012). ATP-gated P2X1 ion channels protect against endotoxemia by dampening neutrophil activation. Journal of Thrombosis and Haemostasis, 10(3), 453-465. https://doi.org/10.1111/j.1538-7836.2011.04606.x

ten Cate, H. (2012). Thrombin generation in clinical conditions. Thrombosis Research, 129(3), 367-370. https://doi.org/10.1016/j.thromres.2011.10.017