Harry Crijns

Professor

Harry Crijns is professor and chair of Cardiology and board member of the Cardiovascular Research Institute Maastricht (CARIM) at Maastricht UMC+. He studied medicine at the University of Amsterdam and was trained in cardiology and electrophysiology in Groningen and Maastricht. He is a Fellow of the ESC and a past board member of the EHRA. He is also past Chair of the Netherlands Society of Cardiology. He served on several guidelines committees for the management of AF. Currently he is the chairman of the scientific advisory board of the Dutch Heart Foundation.

His primary research focus continues to be atrial fibrillation (AF). He founded the RACE trials in the Netherlands and led the Euro Heart Survey on AF (ESC). He has established his reputation by introducing innovative concepts for diagnosis and treatment of AF by showing that - quite contrary to longstanding beliefs - electrical management does not change prognosis. This revolutionised management of the arrhythmia worldwide with the effect that major interventions like electrical cardioversion, catheter ablation and antiarrhythmic drug therapy are applied in a much more personalized fashion.

Subsequently his group showed that rate control in AF can be individualized thereby removing the previously used strict heart rate targets from the international guidelines. He also performed the Euro Heart Survey on AF and made many contributions to the field of stroke management in AF, such as the construction of well-recognised AF specific risk stratification scores for AF progression (HATCH), ischemic stroke (CHA2DS2-VASc) and major bleeding (HAS-BLED). These scores have practically conquered the medical AF community and improved patient care whilst boosting new clinical research throughout the world.

His research group now focusses on recent-onset AF, hybrid AF ablation, upstream therapy and vascular mechanisms for AF progression and stroke in idiopathic atrial fibrillation. He is (co-)author on over 650 scientific articles, with 56,677 citations and Hirsch-index of 100.

Department of Cardiology
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht


  • 2024
    • Velt, M. J. H., Crijns, H. J. G. M., van Gelder, I. C., Linz, D., van de Lande, M. E., Ten Cate, H., Spronk, H. M. H., de Melis, M., Rienstra, M., & Mulder, B. A. (2024). Dynamic biomarker profiles in patients with paroxysmal atrial fibrillation: Assessing the differences between sinus rhythm and acute atrial fibrillation episode. International Journal of Cardiology, 417, Article 132526. https://doi.org/10.1016/j.ijcard.2024.132526
    • Sciacca, V., Sohns, C., Crijns, H. J. G. M., Marrouche, N. F., Schramm, R., Moersdorf, M., Fink, T., Bergau, L., Hindricks, G., Dagres, N., Sossalla, S., Costard-Jaeckle, A., Fox, H., El Hamriti, M., Konietschke, F., Rudolph, V., Gummert, J., Tijssen, J. G. P., Sommer, P., & CASTLE HTx Investigators (2024). Effects of atrial fibrillation ablation on arrhythmia burden and ventricular function in end-stage heart failure: Lessons from CASTLE-HTx. European journal of heart failure. Advance online publication. https://doi.org/10.1002/ejhf.3505
    • van Veldhuisen, D. J., Rienstra, M., Mosterd, A., Alings, A. M., van Asselt, A. D. J., Bouvy, M. L., Tijssen, J. G. P., Schaap, J., van der Wall, E. E., Voors, A. A., Boorsma, E. M., Lok, D. J. A., Crijns, H. J. G. M., Schut, A., Vijver, M. A. T., Voordes, G. H. D., de Vos, A. H., Maas-Soer, E. L., Smit, N. W., ... DECISION Investigators & Commitees (2024). Efficacy and safety of low-dose digoxin in patients with heart failure. Rationale and design of the DECISION trial. European journal of heart failure, 26(10), 2223-2230. https://doi.org/10.1002/ejhf.3428
    • Champsi, A., Mobley, A. R., Subramanian, A., Nirantharakumar, K., Wang, X., Shukla, D., Bunting, K., Molgaard, I., Dwight, J., Casado Arroyo, R., Crijns, H. J. G. M., Guasti, L., Lettino, M., Lumbers, R. T., Maesen, B., Rienstra, M., Svennberg, E., Tica, O., Traykov, V., ... Kotecha, D. (2024). Gender and contemporary risk of adverse events in atrial fibrillation. European Heart Journal, 45(36), 3707-3717. Article ehae539. https://doi.org/10.1093/eurheartj/ehae539
    • Fabritz, L., Al-Taie, C., Borof, K., Breithardt, G., Camm, A. J., Crijns, H. J. G. M., Roth Cardoso, V., Chua, W., van Elferen, S., Eckardt, L., Gkoutos, G., Goette, A., Guasch, E., Hatem, S., Metzner, A., Mont, L., Murukutla, V. A., Obergassel, J., Rillig, A., ... Kirchhof, P. (2024). Biomarker-based prediction of sinus rhythm in atrial fibrillation patients: the EAST-AFNET 4 biomolecule study. European Heart Journal. Advance online publication. https://doi.org/10.1093/eurheartj/ehae611
    • Sohns, C., Moersdorf, M., Marrouche, N. F., Bergau, L., Costard-Jaeckle, A., Crijns, H. J. G. M., Fox, H., Hindricks, G., Dagres, N., Sossalla, S., Schramm, R., Fink, T., El Hamriti, M., Sciacca, V., Didenko, M., Konietschke, F., Rudolph, V., Gummert, J., Tijssen, J. G. P., ... CASTLE HTx Investigators (2024). Catheter Ablation in Patients with End-Stage Heart Failure and Atrial Fibrillation: Two-year Follow-up of the CASTLE-HTx Trial. Circulation. Advance online publication. https://doi.org/10.1161/CIRCULATIONAHA.124.071517
    • van de Kar, M. R. D., van Brakel, T. J., Van't Veer, M., van Steenbergen, G. J., Daeter, E. J., Crijns, H. J. G. M., van Veghel, D., Dekker, L. R. C., & Otterspoor, L. C. (2024). Anticoagulation for post-operative atrial fibrillation after isolated coronary artery bypass grafting: a meta-analysis. European Heart Journal, 45(29), 2620-2630. https://doi.org/10.1093/eurheartj/ehae267
    • Sanders, P., Svennberg, E., Diederichsen, S. Z., Crijns, H. J. G. M., Lambiase, P. D., Boriani, G., & Van Gelder, I. C. (2024). Great debate: device-detected subclinical atrial fibrillation should be treated like clinical atrial fibrillation. European Heart Journal, 45(29), 2594-2603. https://doi.org/10.1093/eurheartj/ehae365
    • Lenting, C. J., Wijtvliet, E. P. J. P., Koldenhof, T., Bessem, B., Pluymaekers, N. A. H. A., Rienstra, M., Folkeringa, R. J., Bronzwaer, P., Elvan, A., Elders, J., Tukkie, R., Luermans, J. G. L. M., Van Kuijk, S. M. J., Tijssen, J. G. P., Van Gelder, I. C., Crijns, H. J. G. M., & Tieleman, R. G. (2024). Previous Exercise Levels and Outcome in Patients with New Atrial Fibrillation: 'Past Achievements Do Not Predict the Future'. Medicine and Science in Sports and Exercise, 56(8), 1349-1354. https://doi.org/10.1249/MSS.0000000000003424
    • Moersdorf, M., Tijssen, J. G. P., Marrouche, N. F., Crijns, H. J. G. M., Costard-Jaeckle, A., Bergau, L., Hindricks, G., Dagres, N., Sossalla, S., Schramm, R., Fox, H., Fink, T., El Hamriti, M., Sciacca, V., Konietschke, F., Rudolph, V., Gummert, J., Sommer, P., Sohns, C., & CASTLE HTx Investigators (2024). Prognosis of patients in end-stage heart failure with atrial fibrillation treated with ablation - Insights from Castle HTX. Heart Rhythm, 21(7), 1008-1015. https://doi.org/10.1016/j.hrthm.2024.04.013
    • Frausing, M. H. J. P., van de Lande, M., Linz, D., Crijns, H. J. G. M., Tieleman, R. G., Hemels, M. E. W., De Melis, M., Schotten, U., Kronborg, M. B., Nielsen, J. C., Van Gelder, I., & Rienstra, M. (2024). Healthcare utilisation and quality of life according to atrial fibrillation burden, episode frequency and duration. Heart. Advance online publication. https://doi.org/10.1136/heartjnl-2024-324016
    • Rillig, A., Eckardt, L., Borof, K., Camm, A. J., Crijns, H. J. G. M., Goette, A., Breithardt, G., Lemoine, M. D., Metzner, A., Rottner, L., Schotten, U., Vettorazzi, E., Wegscheider, K., Zapf, A., Heidbuchel, H., Willems, S., Fabritz, L., Schnabel, R. B., Magnussen, C., & Kirchhof, P. (2024). Safety and efficacy of long-term Sodium Channel Blocker therapy for Early Rhythm Control: The EAST-AFNET 4 trial. EP Europace, 26(6), Article euae121. https://doi.org/10.1093/europace/euae121
    • Ruskin, J. N., Camm, A. J., Dufton, C., Woite-Silva, A. C., Tuininga, Y., Badings, E., De Jong, J. S. S. G., Oosterhof, T., Aksoy, I., Kuijper, A. F. M., Van Gelder, I. C., van Dijk, V., Nuyens, D., Schellings, D., Lee, M. Y., Kowey, P. R., Crijns, H. J. G. M., Maupas, J., Belardinelli, L., & INSTANT Investigators (2024). Orally Inhaled Flecainide for Conversion of Atrial Fibrillation to Sinus Rhythm: INSTANT Phase 2 Trial. JACC: Clinical Electrophysiology, 10(6), 1021-1033. https://doi.org/10.1016/j.jacep.2024.02.021
    • Crijns, H. J. G. M., Lambiase, P. D., & Sanders, P. (2024). The year in cardiovascular medicine 2023: the top 10 papers in arrhythmias. European Heart Journal, 45(19), 1730-1732. https://doi.org/10.1093/eurheartj/ehae189
    • van der Velden, R. M. J., Bonander, C., Crijns, H. J. G. M., Kemp-Gudmundsdottir, K., Engdahl, J., Linz, D., & Svennberg, E. (2024). Adherence to a handheld device-based atrial fibrillation screening protocol is associated with clinical outcomes. Heart, 110(9), 626-634. https://doi.org/10.1136/heartjnl-2023-323522
    • Fabritz, L., Chua, W., Cardoso, V. R., Al-Taie, C., Borof, K., Suling, A., Krause, L., Kany, S., Magnussen, C., Wegscheider, K., Breithardt, G., Crijns, H. J. G. M., Camm, A. J., Gkoutos, G., Ellinor, P. T., Goette, A., Schotten, U., Wienhues-Thelen, U.-H., Zeller, T., ... Kirchhof, P. (2024). Blood-based cardiometabolic phenotypes in atrial fibrillation and their associated risk: EAST-AFNET 4 biomolecule study. Cardiovascular Research, 120(8), 855-868. https://doi.org/10.1093/cvr/cvae067
    • Spoormans, E. M., Lemkes, J. S., Janssens, G. N., van der Hoeven, N. W., Jewbali, L. S. D., Dubois, E. A., Meuwissen, M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R., Vlachojannis, G. J., Eikemans, B. J. W., van der Harst, P., van der Horst, I. C. C., Voskuil, M., van der Heijden, J. J., Beishuizen, A., ... van Royen, N. (2024). The Prognostic Value of Troponin-T in Out-of-Hospital Cardiac Arrest Without ST-Segment Elevation: A COACT Substudy. Journal of the Society for Cardiovascular Angiography and Interventions, 3(2), Article 101191. https://doi.org/10.1016/j.jscai.2023.101191
    • van der Velden, R. M. J., Pluymaekers, N. A. H. A., Dudink, E. A. M. P., Luermans, J. G. L. M., Meeder, J. G., Heesen, W. F., Lenderink, T., Widdershoven, J. W. M. G., Bucx, J. J. J., Rienstra, M., Kamp, O., van Opstal, J. M., Kirchhof, C. J. H. J., van Dijk, V. F., Swart, H. P., Alings, M., Van Gelder, I. C., Crijns, H. J. G. M., & Linz, D. (2024). Cardioversion strategy impacts rate control during recurrences in patients with paroxysmal atrial fibrillation: A subanalysis of the RACE 7 ACWAS trial. Clinical Cardiology, 47(1), Article e24161. https://doi.org/10.1002/clc.24161
  • 2023
    • Mulder, B. A., Khalilian Ekrami, N., Van De Lande, M. E., Nguyen, B.-O., Weberndorfer, V., Crijns, H. J., Geelhoed, B., Blaauw, Y., Hemels, M. E., Tieleman, R. G., Scheerder, C. O., De Melis, M., Schotten, U., Linz, D., Van Gelder, I. C., & Rienstra, M. (2023). Women have less progression of paroxysmal atrial fibrillation: data from the RACE V study. Open Heart, 10(2), Article e002534. https://doi.org/10.1136/openhrt-2023-002534
    • Chua, W., Cardoso, V. R., Guasch, E., Sinner, M. F., Al-Taie, C., Brady, P., Casadei, B., Crijns, H. J. G. M., Dudink, E. A. M. P., Hatem, S. N., Kääb, S., Kastner, P., Mont, L., Nehaj, F., Purmah, Y., Reyat, J. S., Schotten, U., Sommerfeld, L. C., Zeemering, S., ... Fabritz, L. (2023). An angiopoietin 2, FGF23, and BMP10 biomarker signature differentiates atrial fibrillation from other concomitant cardiovascular conditions. Scientific Reports, 13(1), Article 16743. https://doi.org/10.1038/s41598-023-42331-7
    • Frausing, M. H. J. P., van de Lande, M. E., Maass, A. H., Nguyen, B. O., Hemels, M. E. W., Tieleman, R. G., Koldenhof, T., De Melis, M., Linz, D., Schotten, U., Weberndoerfer, V., Crijns, H. J. G. M., Van Gelder, I. C., Nielsen, J. C., & Rienstra, M. (2023). Brady- and tachyarrhythmias detected by continuous rhythm monitoring in paroxysmal atrial fibrillation. Heart, 109(17), 1286-1293. https://doi.org/10.1136/heartjnl-2022-322253
    • van Mourik, M. J. W., Linz, D., Verwijs, H. J. A., Bekkers, S. C. A. M., Weerts, J., Schotten, U., Rocca, H. B.-L., Lumens, J., Crijns, H. J. G. M., Weijs, B., & Knackstedt, C. (2023). Evaluating subclinical left ventricular and left atrial dysfunction in idiopathic atrial fibrillation: A speckle-tracking based strain-analysis. International Journal of Cardiology, 383(1), 159-165. https://doi.org/10.1016/j.ijcard.2023.04.024
    • van der Heijden, C. A. J., Weberndörfer, V., Vroomen, M., Luermans, J. G., Chaldoupi, S. M., Bidar, E., Vernooy, K., Maessen, J. G., Pison, L., van Kuijk, S. M. J., La Meir, M., Crijns, H. J. G. M., & Maesen, B. (2023). Hybrid Ablation Versus Repeated Catheter Ablation in Persistent Atrial Fibrillation: A Randomized Controlled Trial. JACC: Clinical Electrophysiology, 9(7), 1013-1023. https://doi.org/10.1016/j.jacep.2022.12.011
    • Koldenhof, T., Van Gelder, I. C., Crijns, H. J. G. M., Rienstra, M., & Tieleman, R. G. (2023). Rate control in atrial fibrillation, calcium channel blockers versus beta-blockers. Heart, 109(23), 1759 - 1764. https://doi.org/10.1136/heartjnl-2023-322635
    • van der Heijden, C. A. J., Weberndorfer, V., Vroomen, M., Luermans, J. G., Chaldoupi, S.-M., Bidar, E., Vernooy, K., Maessen, J. G., Pison, L., van Kuijk, S. M. J., La Meir, M., Crijns, H. J. G. M., & Maesen, B. (2023). REPLY: Hybrid Ablation for Persistent Atrial Fibrillation: The Approach Matters. JACC: Clinical Electrophysiology, 9(7), 1195-1195. https://doi.org/10.1016/j.jacep.2023.03.018
    • Gottschalk, S., Kany, S., Konig, H. H., Crijns, H. J. G. M., Vardas, P., Camm, A. J., Wegscheider, K., Metzner, A., Rillig, A., Kirchhof, P., & Dams, J. (2023). Cost-effectiveness of early rhythm control vs. usual care in atrial fibrillation care: an analysis based on data from the EAST-AFNET 4 trial. EP Europace, 25(5), Article euad051. https://doi.org/10.1093/europace/euad051
    • van de Lande, M. E., Rama, R. S., Koldenhof, T., Arita, V. A., Nguyen, B. O., van Deutekom, C., Weberndorfer, V., Crijns, H. J. G. M., Hemels, M. E. W., Tieleman, R. G., de Melis, M., Schotten, U., Linz, D., Van Gelder, I. C., Rienstra, M., & RACE V Investigators (2023). Time of onset of atrial fibrillation and atrial fibrillation progression data from the RACE V study. EP Europace, 25(5), Article euad058. https://doi.org/10.1093/europace/euad058
    • Arita, V. A., Van de Lande, M. E., Ekrami, N. K., Nguyen, B. O., Van Melle, J. M., Geelhoed, B., De With, R. R., Weberndorfer, V., Erkuner, O., Hillege, H., Linz, D., Ten Cate, H., Spronk, H. M. H., Koldenhof, T., Tieleman, R. G., Schotten, U., Crijns, H. J. G. M., Van Gelder, I. C., & Rienstra, M. (2023). Clinical utility of the 4S-AF scheme in predicting progression of atrial fibrillation: data from the RACE V study. EP Europace, 25(4), 1323-1331. https://doi.org/10.1093/europace/euac268
    • Altintas, S., van Workum, S., Kok, M., Joosen, I. A. P. G., Versteylen, M. O., Nelemans, P. J., Wildberger, J. E., Crijns, H. J. G. M., Das, M., & Kietselaer, B. L. J. H. (2023). BMI is not independently associated with coronary artery calcification in a large single-center CT cohort. Obesity science & practice, 9(2), 172-178. https://doi.org/10.1002/osp4.636
    • Lambiase, P. D., Sanders, P., & Crijns, H. J. G. M. (2023). The year in cardiovascular medicine 2022: the top 10 papers in arrhythmias. European Heart Journal, 44(5), 345–347. https://doi.org/10.1093/eurheartj/ehac753
    • Nguyen, B. O., Weberndorfer, V., Crijns, H. J. G. M., Geelhoed, B., Ten Cate, H., Spronk, H., Kroon, A., De With, R., Al-Jazairi, M., Maass, A. H., Blaauw, Y., Tieleman, R. G., Hemels, M. E. W., Luermans, J., de Groot, J., Allaart, C. P., Elvan, A., De Melis, M., Scheerder, C., ... Rienstra, M. (2023). Prevalence and determinants of atrial fibrillation progression in paroxysmal atrial fibrillation. Heart, 109(3), 186-194. https://doi.org/10.1136/heartjnl-2022-321027
    • Lambiase, P. D., Sanders, P., & Crijns, H. J. G. M. (2023). The year in cardiovascular medicine 2022: the top 10 papers in arrhythmias. Cardiologia Hungarica, 53(3), 189-192.
    • van der Velden, R. M. J., Pluymaekers, N. A. H. A., Dudink, E. A. M. P., Luermans, J. G. L. M., Meeder, J. G., Heesen, W. F., Lenderink, T., Widdershoven, J. W. M. G., Bucx, J. J. J., Rienstra, M., Kamp, O., van Opstal, J. M., Kirchhof, C. J. H. J., van Dijk, V. F., Swart, H. P., Alings, M., Van Gelder, I. C., Crijns, H. J. G. M., & Linz, D. (2023). Mobile health adherence for the detection of recurrent recent-onset atrial fibrillation. Heart, 109(1), 26-33. https://doi.org/10.1136/heartjnl-2022-321346
  • 2022
    • Martinek, M., Crijns, H. J. G. M., Essers, B. A. B., Wiesinger, R., & Pruckner, G. (2022). Healthcare Utilization and Outcomes in Atrial Fibrillation Patients Treated by Drug Therapy versus a Catheter Ablation Strategy-A Middle European Propensity Score Matched Cohort Study. Journal of Cardiovascular Development and Disease, 9(12), Article 451. https://doi.org/10.3390/jcdd9120451
    • Zeemering, S., Isaacs, A., Winters, J., Maesen, B., Bidar, E., Dimopoulou, C., Guasch, E., Batlle, M., Haase, D., Hatem, S. N., Kara, M., Kääb, S., Mont, L., Sinner, M. F., Wakili, R., Maessen, J., Crijns, H. J. G. M., Fabritz, L., Kirchhof, P., ... Schotten, U. (2022). Atrial fibrillation in the presence and absence of heart failure enhances expression of genes involved in cardiomyocyte structure, conduction properties, fibrosis, inflammation, and endothelial dysfunction. Heart Rhythm, 19(12), 2115-2124. https://doi.org/10.1016/j.hrthm.2022.08.019
    • Vitolo, M., Proietti, M., Malavasi, V. L., Bonini, N., Romiti, G. F., Imberti, J. F., Fauchier, L., Marin, F., Nabauer, M., Potpara, T. S., Dan, G.-A., Kalarus, Z., Maggioni, A. P., Lane, D. A., Lip, G. Y. H., Boriani, G., ESC-EHRA EORP-AF Long-Term General Registry Investigators, Erküner, Ö., & Crijns, H. (2022). Adherence to the "Atrial fibrillation Better Care" (ABC) pathway in patients with atrial fibrillation and cancer: A report from the ESC-EHRA EURObservational Research Programme in atrial fibrillation (EORP-AF) General Long-Term Registry. European journal of internal medicine, 105, 54-62. https://doi.org/10.1016/j.ejim.2022.08.004
    • Eckardt, L., Sehner, S., Suling, A., Borof, K., Breithardt, G., Crijns, H. J. G. M., Goette, A., Wegscheider, K., Zapf, A., Camm, A. J., Metzner, A., & Kirchhof, P. (2022). Attaining sinus rhythm mediates improved outcome with early rhythm control therapy of atrial fibrillation: the EAST - AFNET 4 trial. European Heart Journal, 43(40), 4127-4144. https://doi.org/10.1093/eurheartj/ehac471
    • van der Velden, R. M. J., Hermans, A. N. L., Pluymaekers, N. A. H. A., Gawalko, M., Elliott, A., Hendriks, J. M., Franssen, F. M. E., Slats, A. M., van Empel, V. P. M., Van Gelder, I. C., Thijssen, D. H. J., Eijsvogels, T. M. H., Leue, C., Crijns, H. J. G. M., Linz, D., & Simons, S. O. (2022). Dyspnea in patients with atrial fibrillation: Mechanisms, assessment and an interdisciplinary and integrated care approach. IJC Heart and Vasculature, 42, Article 101086. https://doi.org/10.1016/j.ijcha.2022.101086
    • Garcia, R., Clouard, M., Plank, F., Degand, B., Philibert, S., Laurent, G., Poupin, P., Sakhy, S., Gras, M., Stühlinger, M., Szegedi, N., Herczeg, S., Simon, J., Crijns, H. J. G. M., Marijon, E., Christiaens, L., & Guenancia, C. (2022). Asymptomatic left circumflex artery stenosis is associated with higher arrhythmia recurrence after persistent atrial fibrillation ablation. Frontiers in Cardiovascular Medicine, 9, Article 873135. https://doi.org/10.3389/fcvm.2022.873135
    • Rillig, A., Borof, K., Breithardt, G., Camm, A. J., J G M Crijns, H., Goette, A., Kuck, K.-H., Metzner, A., Vardas, P., Vettorazzi, E., Wegscheider, K., Zapf, A., & Kirchhof, P. (2022). Early Rhythm Control in Patients With Atrial Fibrillation and High Comorbidity Burden. Circulation, 146(11), 836-847. https://doi.org/10.1161/circulationaha.122.060274
    • Gulpen, A. J. W., Braeken, D. C. W., Schalla, S., Ten Cate, H., Crijns, H. J., & Ten Cate-Hoek, A. J. (2022). Long-Term Adherence to Direct Oral Anticoagulants in Patients with Atrial Fibrillation: A Comparative Cross-Sectional Study. Acta Haematologica, 145(5), 476-483. https://doi.org/10.1159/000524094
    • Gawałko, M., Agbaedeng, T. A., Saljic, A., Müller, D. N., Wilck, N., Schnabel, R., Penders, J., Rienstra, M., van Gelder, I., Jespersen, T., Schotten, U., Crijns, H. J. G. M., Kalman, J. M., Sanders, P., Nattel, S., Dobrev, D., & Linz, D. (2022). Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications. Cardiovascular Research, 118(11), 2415-2427. https://doi.org/10.1093/cvr/cvab292
    • Van Mourik, M. J. W., Arita, V. A., Lyon, A., Lumens, J., De With, R. R., van Melle, J. P., Schotten, U., Bekkers, S. C. A. M., Crijns, H. J. G. M., Van Gelder, I. C., Rienstra, M., & Linz, D. K. (2022). Association between comorbidities and left and right atrial dysfunction in patients with paroxysmal atrial fibrillation: Analysis of AF-RISK. International Journal of Cardiology, 360, 29-35. https://doi.org/10.1016/j.ijcard.2022.05.044
    • Goette, A., Borof, K., Breithardt, G., Camm, A. J., Crijns, H. J. G. M., Kuck, K.-H., Wegscheider, K., Kirchhof, P., & EAST-AFNET 4 Investigators (2022). Presenting Pattern of Atrial Fibrillation and Outcomes of Early Rhythm Control Therapy. Journal of the American College of Cardiology, 80(4), 283-295. https://doi.org/10.1016/j.jacc.2022.04.058
    • Spoormans, E. M., Lemkes, J. S., Janssens, G. N., Soultana, O., van der Hoeven, N. W., Jewbali, L. S. D., Dubois, E. A., Meuwissen, M., Rijpstra, T. A., Bosker, H. A., Blans, M. J., Bleeker, G. B., Baak, R., Vlachojannis, G. J., Eikemans, B. J. W., van der Harst, P., van der Horst, I. C. C., Voskuil, M., van der Heijden, J. J., ... van Royen, N. (2022). Ischaemic electrocardiogram patterns and its association with survival in out-of-hospital cardiac arrest patients without ST-segment elevation myocardial infarction: a COACT trials' post-hoc subgroup analysis. European Heart Journal: Acute Cardiovascular Care, 11(7), 535-543. https://doi.org/10.1093/ehjacc/zuac060
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