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CARIM's Confidential Contact Persons

CARIM's Confidential Contact Persons

27 November 2024

Dr Magdi Nagy (Dept of Biochemistry) and Prof. Peter de Leeuw (Dept of Internal Medicine) have been appointed as CARIM Confidential Contact Persons.

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ZonMw grant on appropriate palliative care

ZonMw grant on appropriate palliative care

27 November 2024

Prof. Marc Hemmelder (Dept of Internal Medicine) and his team received a ZonMw grant to promote early palliative care for dialysis patients who are non-waitlisted for transplantation.

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Carim Maastricht
Carim Maastricht

Michael Jacobs

Professor

Prof. Michael Jacobs has obtained his medical doctor degree at the University of Limburg, Maastricht. His PhD research focussed on microcirculation in patients with peripheral arterial disease. Following his surgical residency, he was trained as a cardiovascular surgeon at the Texas Heart Institute in Houston, USA. He was appointed chief of vascular surgery at the Amsterdam Medical Center in 1992 and started research programmes concentrating on assessment of spinal cord function in thoraco-abdominal aortic aneurysm (TAAA) repair and preventive strategies by means of selective organ perfusion and motor evoked potentials. In 2000, he was invited to Maastricht UMC+ to chair the Department of Surgery and create an integrated heart- and vascular center (HVC). Research addressed pre-operative imaging of the blood supplying arteries of the spinal cord in TAAA patients, and the role of arginine and nitric oxide (NO) metabolism in patients undergoing extensive aortic repair. In 2005, he also accepted the chair of Vascular Surgery at the RWTH University Hospital in Aachen, Germany.

He yearly organises the European Vascular Course, hosting around 2,000 cardiovascular specialists from all over the world.

Michael-jacobs

Department of Vascular Surgery
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht                                                                                                      T: +31(0)43 387 22 79

  • 2017
    • Gombert, A., Grommes, J., Schick, G., Binneboesel, M., Klink, C., Jacobs, M. J., & Kotelis, D. (2017). Sarcoidosis-Associated Aortoesophageal Fistula-Multistage Interdisciplinary Surgical Therapy for a Rare and Life-Threatening Condition. Annals of Vascular Surgery, 39, 287.e15-287 e.20. https://doi.org/10.1016/j.avsg.2016.06.034
  • 2016
  • 2015
    • Akhtar, S., Hartmann, P., Karshovska, E., Rinderknecht, F.-A., Subramanian, P., Gremse, F., Grommes, J., Jacobs, M., Kiessling, F., Weber, C., Steffens, S., & Schober, A. (2015). Endothelial Hypoxia-Inducible Factor-1 alpha Promotes Atherosclerosis and Monocyte Recruitment by Upregulating MicroRNA-19a. Hypertension, 66(6), 1220-1226. https://doi.org/10.1161/HYPERTENSIONAHA.115.05886
    • Gombert, A., Kalder, J., Mull, M., Greiner, A., Jalaie, H., Jacobs, M., & Grommes, J. (2015). The Compression Syndrome of Lumbar Arteries - Case Report of a Rare Disease Pattern. Zentralblatt für Chirurgie, 140(5), 525-529. https://doi.org/10.1055/s-0035-1546015
    • Jacobs, M., & Schurink, G. W. (2015). Commentary on 'Short-term Outcome of Spinal Cord lschemia after Endovascular Repair of Thoracoabdominal Aortic Aneurysms'. European Journal of Vascular and Endovascular Surgery, 49(4), 410-411. https://doi.org/10.1016/j.ejvs.2015.01.003
    • Mees, B. M. E., Peppelenbosch, A. G., De Haan, M. W., Jacobs, M. J. H. M., & Schurink, G. W. H. (2015). Contemporary management of the demanding infrarenal neck in abdominal aortic aneurysm repair. Journal of Cardiovascular Surgery, 56(2), 239-247.
    • Schurink, G. W. H., Peppelenbosch, A. G., Mees, B. M. E., De Haan, M. W., & Jacobs, M. J. H. M. (2015). Strategies to prevent spinal cord ischemia in thoracoabdominal aortic aneurysm repair. Journal of Cardiovascular Surgery, 56(2), 281-286.
    • Gombert, A., Jalaie, H., Jacobs, M., & Grommes, J. (2015). Popliteal Artery Aneurysma as an Important Differential Diagnosis. Sportverletzung-sportschaden, 29(1), 51-52. https://doi.org/10.1055/s-0034-1385612
    • Jacobs, M., Mees, B., & Schurink, G. (2015). Endovascular options in the descending thoracic aorta in CTD. Endovascular Today.
  • 2014
    • Grommes, J., Greiner, A., Bendermacher, B., Erlmeier, M., Frech, A., Belau, P., Kennes, L. N., Fraedrich, G., Schurink, G. W., Jacobs, M. J., & Klocker, J. (2014). Risk factors for mortality and failure of conservative treatment after aortic type B dissection. Journal of Thoracic and Cardiovascular Surgery, 148(5), 2155-2160.e1. https://doi.org/10.1016/j.jtcvs.2014.03.053
    • Jalaie, H., Grommes, J., Sailer, A., Greiner, A., Binneboesel, M., Kalder, J., Schurink, G. W., & Jacobs, M. (2014). Treatment of Symptomatic Aberrant Subclavian Arteries. European Journal of Vascular and Endovascular Surgery, 48(5), 521-526. https://doi.org/10.1016/j.ejvs.2014.06.040
    • Vermeulen Windsant, I. C., de Wit, N. C., Sertorio, J. T., van Bijnen, A. A., Ganushchak, Y. M., Heijmans, J. H., Tanus-Santos, J. E., Jacobs, M. J., Maessen, J. G., & Buurman, W. A. (2014). Hemolysis during cardiac surgery is associated with increased intravascular nitric oxide consumption and perioperative kidney and intestinal tissue damage. Frontiers in physiology, 5, Article 340. https://doi.org/10.3389/fphys.2014.00340
    • Schleimer, K., Kalder, J., Grommes, J., Jalaie, H., Tawadros, S., Greiner, A., Jacobs, M., & Kokozidou, M. (2014). Heterotopic Auxiliary Rat Liver Transplantation With Flow-regulated Portal Vein Arterialization in Acute Hepatic Failure. Journal of visualized experiment, 13(91), Article e51115. https://doi.org/10.3791/51115
    • Vijayan, S., Asare, Y., Grommes, J., Soehnlein, O., Lutgens, E., Shagdarsuren, G., Togtokh, A., Jacobs, M. J., Fischer, J. W., Bernhagen, J., Weber, C., Schober, A., & Shagdarsuren, E. (2014). High Expression of C5L2 Correlates with High Proinflammatory Cytokine Expression in Advanced Human Atherosclerotic Plaques. American Journal of Pathology, 184(7), 2123-2133. https://doi.org/10.1016/j.ajpath.2014.04.004
    • Jacobs, M. J., & Schurink, G. W. (2014). Open repair in chronic type B dissection with connective tissue disorders. Annals of Cardiothoracic Surgery, 3(3), 325-8. https://doi.org/10.3978/j.issn.2225-319X.2014.05.02
    • Kalder, J., Keschenau, R., Tamm, M., Jalaie, H., Jacobs, M., & Greiner, A. (2014). Anatomic changes of target vessels after fenestrated and branched aortic aneurysm repair. Journal of Cardiovascular Surgery, 55(2), 115-121.
    • Kalder, J., Jalaie, H., Greiner, A., & Jacobs, M. (2014). A new shunting concept to prevent lower limb ischemia/reperfusion injury in prolonged fenestrated stent-graft procedures. Journal of Cardiovascular Surgery, 55(2), 183-185.
    • Sailer, A. M., de Haan, M. W., Peppelenbosch, A. G., Jacobs, M., Wildberger, J. E., & Schurink, G. W. H. (2014). CTA with Fluoroscopy Image Fusion Guidance in Endovascular Complex Aortic Aneurysm Repair. European Journal of Vascular and Endovascular Surgery, 47(4), 349-356. https://doi.org/10.1016/j.ejvs.2013.12.022
    • Greiner, A., Schleimer, K., Jalaie, H., Gombert, A., Jacobs, M., & Kalder, J. (2014). Late rupture after EVAR: a new trend?Journal of Cardiovascular Surgery, 55(2), 169-174.
    • Hohn, N., Langer, S., Kalder, J., Jacobs, M., Marx, G., & Eisert, A. (2014). Optimizing the pharmacotherapy of vascular surgery patients by medication reconciliation. Journal of Cardiovascular Surgery, 55(2), 175-181.
    • Schurink, G. W. H., De Roo, R., De Haan, M. W., Peppelenbosch, A. G., & Jacobs, M. (2014). The current endovascular therapeutic spectrum for short neck and juxtarenal aneurysms. Journal of Cardiovascular Surgery, 55(2), 85-93.
  • 2013
    • Greiner, A., Grommes, J., & Jacobs, M. J. (2013). The Place of Endovascular Treatment in Abdominal Aortic Aneurysm. Deutsches Arzteblatt International, 110(8), 119-125. https://doi.org/10.3238/arztebl.2013.0119
    • Grommes, J., Binneboesel, M., Klink, C. D., von Trotha, K. T., Schleimer, K., Jacobs, M. J., Neumann, U. P., & Krones, C. J. (2013). Comparison of Intestinal Microcirculation and Wound Healing in a Rat Model. Journal of Investigative Surgery, 26(1), 46-52. https://doi.org/10.3109/08941939.2012.692759
    • Schurink, G. W. H., De Haan, M. W., Peppelenbosch, A. G., Mess, W., & Jacobs, M. (2013). Spinal cord function monitoring during endovascular treatment of thoracoabdominal aneurysms: implications for staged procedures. Journal of Cardiovascular Surgery, 54(1), 117-124.
    • Kalder, J., Greiner, A., Grommes, J., Mahnken, A., Jalaie, H., & Jacobs, M. (2013). Thoracoabdominal aneurysms and changes in adjacent vertebral bodies. Journal of Cardiovascular Surgery, 54(1), 135-139.
  • 2012
    • Greiner, A., & Jacobs, M. (2012). Aortic centers. Gefässchirurgie, 17(5), 317–322. https://doi.org/10.1007/s00772-012-1044-1
    • Grommes, J., Vijayan, S., Drechsler, M., Hartwig, H., Moergelin, M., Dembinski, R., Jacobs, M., Koeppel, T. A., Binneboesel, M., Weber, C., & Soehnlein, O. (2012). Simvastatin Reduces Endotoxin-Induced Acute Lung Injury by Decreasing Neutrophil Recruitment and Radical Formation. PLOS ONE, 7(6), Article e38917. https://doi.org/10.1371/journal.pone.0038917
    • Hanssen, S. J. P., van de Poll, M. C. G., Houben, A. J., Vermeulen Windsant, I. C., Snoeijs, M. G., Bekers, O., Buurman, W. A., & Jacobs, M. J. H. M. (2012). Hemolysis compromises nitric oxide-dependent vasodilatory responses in patients undergoing major cardiovascular surgery.Thoracic and Cardiovascular Surgeon, 60(4), 255-261. https://doi.org/10.1055/s-0031-1299571
    • Greiner, A., Mess, W. H., Schmidli, J., Debus, E. S., Grommes, J., Dick, F., & Jacobs, M. J. (2012). Cyber medicine enables remote neuromonitoring during aortic surgery. Journal of Vascular Surgery, 55(5), 1227-1233. https://doi.org/10.1016/j.jvs.2011.11.121
    • Vermeulen Windsant, I. C., Hellenthal, F. A., Derikx, J. P. M., Prins, M. H., Buurman, W. A., Jacobs, M. J. H. M., & Schurink, G. W. H. (2012). Circulating Intestinal Fatty Acid-Binding Protein as an Early Marker of Intestinal Necrosis After Aortic Surgery: A Prospective Observational Cohort Study. Annals of Surgery, 255(4), 796-803. https://doi.org/10.1097/SLA.0b013e31824b1e16
    • Grommes, J., Alard, J.-E., Drechsler, M., Wantha, S., Morgelin, M., Kuebler, W. M., Jacobs, M., von Hundelshausen, P., Markart, P., Wygrecka, M., Preissner, K. T., Hackeng, T. M., Koenen, R. R., Weber, C., & Soehnlein, O. (2012). Disruption of Platelet-derived Chemokine Heteromers Prevents Neutrophil Extravasation in Acute Lung Injury. American Journal of Respiratory and Critical Care Medicine, 185(6), 628-636. https://doi.org/10.1164/rccm.201108-1533OC
    • Rowinska, Z., Zander, S., Zernecke, A., Jacobs, M., Langer, S., Weber, C., Merx, M. W., & Koeppel, T. A. (2012). Non- invasive in vivo analysis of a murine aortic graft using high resolution ultrasound microimaging. European Journal of Radiology, 81(2), 244-249. https://doi.org/10.1016/j.ejrad.2010.12.083
    • Vermeulen Windsant, I. C., Wit, N. C., Sertorio, J. T., Beckers, E. A., Tanus Santos, J. E., Jacobs, M. J. H. M., & Buurman, W. A. (2012). Blood transfusions increase circulating plasma free hemoglobin levels and plasma nitric oxide consumption: a prospective observational pilot study. Critical Care, 16(3), R95. Article 95. https://doi.org/10.1186/cc11359
    • Kalder, J., Keschenau, P., Hanssen, S. J. P., Greiner, A., Vermeulen Windsant, I. C., Kennes, L. N., Tolba, R., Prinzen, F. W., Buurman, W. A., Jacobs, M. J. H. M., & Koeppel, T. A. (2012). The impact of selective visceral perfusion on intestinal macrohemodynamics and microhemodynamics in a porcine model of thoracic aortic cross-clamping.Journal of Vascular Surgery, 56(1), 149-158. https://doi.org/10.1016/j.jvs.2011.11.126
  • 2011
    • Vermeulen Windsant, I. C., Hanssen, S. J. P., Buurman, W. A., & Jacobs, M. J. H. M. (2011). Cardiovascular surgery and organ damage: Time to reconsider the role of hemolysis. Journal of Thoracic and Cardiovascular Surgery, 142(1), 1-11. https://doi.org/10.1016/j.jtcvs.2011.02.012
    • Bendermacher, B. L. W., Peppelenbosch, A. G., Daemen, J. W. H. C., Lashof, A. M. L. O., & Jacobs, M. J. (2011). Q fever (Coxiella burnetii) causing an infected thoracoabdominal aortic aneurysm. Journal of Vascular Surgery, 53(5), 1402-1404. https://doi.org/10.1016/j.jvs.2010.11.102
    • Bosman, W.-M. P. F., Hinnen, J.-W., van der Steenhoven, T. J., de Vries, A. C., Brom, H. L. F., Jacobs, M. J., & Hamming, J. F. (2011). Treatment of Types II-IV Endo leaks by Injecting Biocompatible Elastomer (PDMS) in the Aneurysm Sac: An In Vitro Study. Journal of Endovascular Therapy, 18(2), 205-213. https://doi.org/10.1583/10-3251.1
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