Bram Kroon

Professor

Bram Kroon is Pprofessor of Vascular Medicine and Chair of the section of Vascular Medicine of the Department of Internal Medicine at the Maastricht UMC+, and since 2013 Principal Investigator for 'vascular complications of diabetes and hypertension' with a special focus on hypertension and arterial stiffening at CARIM. Bram (A.A.) Kroon (born Geleen, 1959) obtained an MD at the Radboud University in Nijmegen (1984). He was registered as internist in 1990 and obtained a PhD in 1996 (Radboud University Medical Center, Nijmegen). In 2010, he accepted the position as Chair of the section of Vascular Medicine, a subdivision of the Department of Internal Medicine. In 2016, he was appointed Professor of Vascular Medicine. Nationwide, he holds the Chair of educational board for Vascular Medicine specialists and is member of the Concilium Medicinae Internae since 2015. He is a board member of the European Society of Hypertension (ESH) Working Group of Intervention Treatment of Hypertension and a member of the ESH Working Group of Hypertension and the Kidney.

Department of Internal Medicine
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
T: +31 (0)43 387 50 05 (4)

  • 2012
    • Boesten, J. E. J., Kaper, J., Stoffers, H. E. J. H., Kroon, A. A., & van Schayck, O. C. P. (2012). Rimonabant improves obesity but not the overall cardiovascular risk and quality of life; results from CARDIO-REDUSE (CArdiometabolic Risk reDuctIOn by Rimonabant: the Effectiveness in Daily practice and its USE). Family Practice, 29(5), 521-527. https://doi.org/10.1093/fampra/cms013
    • Alnima, T., Scheffers, I., De Leeuw, P. W., Winkens, B., Jongen-Vancraybex, H., Tordoir, J. H. M., Schmidli, J., Mohaupt, M. G., Allemann, Y., & Kroon, A. A. (2012). Sustained acute voltage-dependent blood pressure decrease with prolonged carotid baroreflex activation in therapy-resistant hypertension. Journal of Hypertension, 30(8), 1665-1670. https://doi.org/10.1097/HJH.0b013e3283551f10
    • Rouhl, R. P. W., Damoiseaux, J. G. M. C., Lodder, J., Theunissen, R. O. M. F. I. H., Knottnerus, I. L. H., Staals, J., Henskens, L. H. G., Kroon, A. A., de Leeuw, P. W., Tervaert, J. W. C., & van Oostenbrugge, R. J. (2012). Vascular inflammation in cerebral small vessel disease. Neurobiology of Aging, 33(8), 1800-1806. https://doi.org/10.1016/j.neurobiolaging.2011.04.008
    • Ronden, R. A., Houben, A. J. H. M., Teerlink, T., Bakker, J. A., Bierau, J., Stehouwer, C. D. A., De Leeuw, P. W., & Kroon, A. A. (2012). Reduced renal plasma clearance does not explain increased plasma asymmetric dimethylarginine in hypertensive subjects with mild to moderate renal insufficiency. American Journal of Physiology-Renal Physiology, 303(1), F149-F156. https://doi.org/10.1152/ajprenal.00045.2012
    • van Onzenoort, H. A. W., Verberk, W. J., Kroon, A. A., Kessels, A. G. H., Neef, C., van der Kuy, P. H. M., & de Leeuw, P. W. (2012). Electronic monitoring of adherence, treatment of hypertension, and blood pressure control. American Journal of Hypertension, 25(1), 54-59. https://doi.org/10.1038/ajh.2011.153
    • Rouhl, R. P. W., Mertens, A. E. C. S., van Oostenbrugge, R. J., Damoiseaux, J. G. M. C., Debrus-Palmans, L. L., Henskens, L. H. G., Kroon, A. A., de Leeuw, P. W., Lodder, J., & Tervaert, J. W. C. (2012). Angiogenic T-Cells and Putative Endothelial Progenitor Cells in Hypertension-Related Cerebral Small Vessel Disease. Stroke, 43(1), 256-U509. https://doi.org/10.1161/STROKEAHA.111.632208
    • Hoppe, U. C., Brandt, M.-C., Wachter, R., Beige, J., Rump, L. C., Kroon, A. A., Cates, A. W., Lovett, E. G., & Haller, H. (2012). Minimally invasive system for baroreflex activation therapy chronically lowers blood pressure with pacemaker-like safety profile: results from the Barostim neo trial. Journal of the American Society of Hypertension, 6(4), 270-276. https://doi.org/10.1016/j.jash.2012.04.004
  • 2011
    • van Onzenoort, H. A. W., Menger, F. E., Neef, C., Verberk, W. J., Kroon, A. A., de Leeuw, P. W., & van der Kuy, P.-H. M. (2011). Participation in a Clinical Trial Enhances Adherence and Persistence to Treatment A Retrospective Cohort Study. Hypertension, 58(4), 573-578. https://doi.org/10.1161/HYPERTENSIONAHA.111.171074
    • Weijs, B., Blaauw, Y., Rennenberg, R. J. M. W., Schurgers, L. J., Timmermans, C. C. M. M., Pison, L., Nieuwlaat, R., Hofstra, L., Kroon, A. A., Wildberger, J., & Crijns, H. J. G. M. (2011). Patients using vitamin K antagonists show increased levels of coronary calcification: an observational study in low-risk atrial fibrillation patients. European Heart Journal, 32(20), 2555-2562. https://doi.org/10.1093/eurheartj/ehr226
    • Maitland-van der Zee, A.-H., van Wieren-de Wijer, D. B. M. A., de Boer, A., Kroon, A. A., de Leeuw, P. W., Schiffers, P., Janssen, R. G. J. H., Psaty, B. M., Duijn, C. M. V., Stricker, B. H. C., & Klungel, O. H. (2011). Genetic variation in the renin-angiotensin system, use of renin-angiotensin system inhibitors and the risk of myocardial infarction. Journal of the Renin-angiotensin-aldosterone System, 12(3), 208-214. https://doi.org/10.1177/1470320310391834
    • Bisognano, J. D., Bakris, G., Nadim, M. K., Munoz Sanchez, J. L., Kroon, A. A., Schafer, J., de Leeuw, P. W., & Sica, D. A. (2011). Baroreflex Activation Therapy Lowers Blood Pressure in Patients With Resistant Hypertension Results From the Double-Blind, Randomized, Placebo-Controlled Rheos Pivotal Trial. Journal of the American College of Cardiology, 58(7), 765-773. https://doi.org/10.1016/j.jacc.2011.06.008
    • van den Born, B. J. H., Beutler, J. J., Gaillard, C. A. J. M., de Gooijer, A., van den Meiracker, A. H., & Kroon, A. A. (2011). Dutch guideline for the management of hypertensive crisis-2010 revision. Netherlands Journal of Medicine, 69(5), 248-255.
    • Krum, H., Schlaich, M., Sobotka, P., Scheffers, I., Kroon, A. A., & de Leeuw, P. W. (2011). Novel procedure- and device-based strategies in the management of systemic hypertension. European Heart Journal, 32(5), 537-544. https://doi.org/10.1093/eurheartj/ehq457
    • Mulders, T. A., Meyer, Z., van der Donk, C. F. M., Kroon, A. A., Ferreira, I., Stehouwer, C. D. A., & Pinto-Sietsma, S. J. (2011). Patients with premature cardiovascular disease and a positive family history for cardiovascular disease are prone to recurrent events.International Journal of Cardiology, 153(1), 64-67. https://doi.org/10.1016/j.ijcard.2010.08.040
    • Henskens, L. H. G., van Boxtel, M. P. J., Kroon, A. A., van Oostenbrugge, R. J., Lodder, J., & de Leeuw, P. W. (2011). Sleep disturbance increases the nocturnal blood pressure level and attenuates the correlation with target organ damage. Journal of Hypertension, 29(2), 242-250. https://doi.org/10.1097/HJH.0b013e32834192d5
    • Baartmans, M. G. A., Dokter, J., Hollander, C. F., Kroon, A. A., & Oranje, A. P. (2011). Use of Skin Substitute Dressings in the Treatment of Staphylococcal Scalded Skin Syndrome in Neonates and Young Infants. Neonatology, 100(1), 9-13. https://doi.org/10.1159/000317997
  • 2010
    • Rouhl, R. P. W., van Oostenbrugge, R. J., Theunissen, R. O. M. F. I. H., Knottnerus, I. L. H., Staals, J., Henskens, L. H. G., Kroon, A. A., de Leeuw, P. W., Lodder, J., Tervaert, J. W. C., & Damoiseaux, J. G. M. C. (2010). Autoantibodies Against Oxidized Low-Density Lipoprotein in Cerebral Small Vessel Disease. Stroke, 41(11), 2687-2689. https://doi.org/10.1161/STROKEAHA.110.592725
    • Scheffers, I. J. M., Kroon, A. A., Schmidli, J., Jordan, J., Tordoir, J. H. M., Mohaupt, M. G., Luft, F. C., Haller, H., Menne, J., Engeli, S., Ceral, J., Eckert, S., Erglis, A., Narkiewicz, K., Philipp, T., & de Leeuw, P. W. (2010). Novel Baroreflex Activation Therapy in Resistant Hypertension Results of a European Multi-Center Feasibility Study. Journal of the American College of Cardiology, 56(15), 1254-1258. https://doi.org/10.1016/j.jacc.2010.03.089
    • Rennenberg, R. J. M. W., van Varik, B. J., Schurgers, L. J., Hamulyak, K., ten Cate, H., Leiner, T., Vermeer, C., de Leeuw, P. W., & Kroon, A. A. (2010). Chronic coumarin treatment is associated with increased extracoronary arterial calcification in humans. Blood, 115(24), 5121-5123. https://doi.org/10.1182/blood-2010-01-264598
    • Rennenberg, R. J. M. W., de Leeuw, P. W., Kessels, A. G. H., Schurgers, L. J., Vermeer, C., van Engelshoven, J. M. A., Kemerink, G. J., & Kroon, A. A. (2010). Calcium scores and matrix Gla protein levels: association with vitamin K status. European Journal of Clinical Investigation, 40(4), 344-349. https://doi.org/10.1111/j.1365-2362.2010.02275.x
    • Scheffers, I. J. M., Kroon, A. A., & de Leeuw, P. W. (2010). Carotid Baroreflex Activation: Past, Present, and Future. Current Hypertension Reports, 12(2), 61-66. https://doi.org/10.1007/s11906-009-0087-5
    • van Onzenoort, H. A. W., Verberk, W. J., Kroon, A. A., Kessels, A. G. H., Nelemans, P. J., van der Kuy, P.-H. M., Neef, C., & de Leeuw, P. W. (2010). Effect of self-measurement of blood pressure on adherence to treatment in patients with mild-to-moderate hypertension. Journal of Hypertension, 28(3), 622-627. https://doi.org/10.1097/HJH.0b013e328334f36b
    • van Onzenoort, H. A. W., Verberk, W. J., Kessels, A. G. H., Kroon, A. A., Neef, C., van der Kuy, P.-H. M., & de Leeuw, P. W. (2010). Assessing Medication Adherence Simultaneously by Electronic Monitoring and Pill Count in Patients With Mild-to-Moderate Hypertension. American Journal of Hypertension, 23(2), 149-154. https://doi.org/10.1038/ajh.2009.207
    • Staals, J., Henskens, L. H. G., Delanghe, J. R., van Oostenbrugge, R. J., Kessels, A. G., Kroon, A. A., de Leeuw, P. W., & Lodder, J. (2010). Haptoglobin Phenotype Correlates with the Extent of Cerebral Deep White Matter Lesions in Hypertensive Patients. Current Neurovascular Research, 7(1), 1-5. https://doi.org/10.2174/156720210790820163
    • Rennenberg, R. J. W. M., Schurgers, L. J., Kroon, A. A., & Stehouwer, C. D. A. (2010). Arterial calcifications. Journal of Cellular and Molecular Medicine, 14(9), 2203-2210. https://doi.org/10.1111/j.1582-4934.2010.01139.x
    • Ronden, R. A., Houben, A. J. H. M., Kessels, A. G. H., Stehouwer, C. D. A., de Leeuw, P. W., & Kroon, A. A. (2010). Predictors of clinical outcome after stent placement in atherosclerotic renal artery stenosis: a systematic review and meta-analysis of prospective studies.Journal of Hypertension, 28(12), 2370-2377. https://doi.org/10.1097/HJH.0b013e32833ec392
    • Hermeling, E., Hoeks, A. P. G., Winkens, M. H. M., Waltenberger, J. L., Reneman, R. S., Kroon, A. A., & Reesink, K. D. (2010). Noninvasive Assessment of Arterial Stiffness Should Discriminate Between Systolic and Diastolic Pressure Ranges. Hypertension, 55(1), 124-130. https://doi.org/10.1161/HYPERTENSIONAHA.109.143867
  • 2007
    • Hermans, M. M. H., Kooman, J. P., Meinders, J. M., van der Sande, F. M., Brandenburg, V., Ketteler, M., Damoiseaux, J. G. M. C., Cohen Tervaert, J. W., Ferreira, I., Konings, C. J. A. M., Rensma, P. L., Gladziwa, U., Kroon, A. A., Hoeks, A. P. G., Stehouwer, C. D. A., & Leunissen, K. M. L. (2007). Spatial inhomogeneity of common carotid artery intima media is increased in dialysis patients and is independently related to antibodies to oxidized-LDL and serum fetuin-A concentration. Nephrology Dialysis Transplantation, 22 (4), 1205-1212. https://doi.org/10.1093/ndt/gfl750
    • Verberk, W. J., Kroon, A. A., Jongen-Vancraybex, H. A., & de Leeuw, P. W. (2007). The applicability of home blood pressure measurement in clinical practice: a review of literature. Vascular health and risk management, 3(6), 959-966.
  • 2006
    • van Boxtel, M. P. J., Henskens, L. H. G., Kroon, A. A., Hofman, P. A. M., Gronenschild, E. H. B. M., Jolles, J., & de Leeuw, P. W. (2006). Ambulatory blood pressure, asymptomatic cerebrovascular damage and cognitive function in essential hypertension. Journal of Human Hypertension, 20, 5-13. https://doi.org/10.1038/sj.jhh.1001934
  • 2005
    • Hommels, M. J., van der Ven, A., Kroon, A. A., Kessels, A. G. H., van Dieijen-Visser, M. P., van Engelshoven, J. M. A., Bruggeman, C. A., & de Leeuw, P. W. (2005). C-reactive protein, atherosclerosis and kidney function in hypertensive patients. Journal of Human Hypertension, 19(7), 521-526. https://doi.org/10.1038/sj.jhh.1001878
  • 2004
    • van Onna, M. J. H., Kroon, A. A., Houben, A. J. H. M., Koster, D., Zeegers, M. P. A., Henskens, L. H. G., Plat, A. W., Stoffers, H. E. J. H., & de Leeuw, P. W. (2004). Genetic risk of atherosclerotic renal artery disease: the candidate gene approach in a renal angiography cohort. Hypertension, 44(4), 448-453. https://doi.org/10.1161/01.HYP.0000141440.02210.da
  • 2003
    • Henskens, L. H. G., Spiering, W., Stoffers, H. E. J. H., Soomers, F. L. M., Vlietinck, R. F. M., de Leeuw, P. W., & Kroon, A. A. (2003). Effects of ACE I/D and AT1R-A1166C polymorphisms on blood pressure in a healthy normotensive primary care population: first results of the Hippocates study. Journal of Hypertension, 21(1), 81-86. https://doi.org/10.1097/00004872-200301000-00017
    • Rodriguez-Hernandez, S., Kroon, A. A., van Boxtel, M. P. J., Mess, W. H., Lodder, J., Jolles, J., & de Leeuw, P. W. (2003). Is there a side predilection for cerebrovascular disease?Hypertension, 42, 56-60. https://doi.org/10.1161/01.HYP.0000077983.66161.6F
  • 2002
    • Rodriguez-Hernandez, S., van Boxtel, M. P. J., Kroon, A. A., Mess, W. H., Lodder, J., & Jolles, J. (2002). Carotid intima media thickness asymetry in an untreated uncomplicated hypertensive population.Cerebrovascular Diseases, 13(suppl 4, 1-53.