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de Courten, B., de Courten, M. P. J., Soldatos, G., Dougherty, S. L., Straznicky, N., Schlaich, M., Sourris, K. C., Chand, V., Scheijen, J. L. J. M., Kingwell, B. A., Cooper, M. E., Schalkwijk, C. G., Walker, K. Z., & Forbes, J. M. (2016). Diet low in advanced glycation end products increases insulin sensitivity in healthy overweight individuals: a double-blind, randomized, crossover trial. American Journal of Clinical Nutrition, 103(6), 1426-1433. https://doi.org/10.3945/ajcn.115.125427

Hertle, E., Arts, I. C. W., van der Kallen, C. J. H., Feskens, E. J. M., Schalkwijk, C. G., Hoffmann-Petersen, I. T., Thiel, S., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2016). Distinct Longitudinal Associations of MBL, MASP-1, MASP-2, MASP-3, and MAp44 With Endothelial Dysfunction and Intima-Media Thickness The Cohort on Diabetes and Atherosclerosis Maastricht (CODAM) Study. Arteriosclerosis Thrombosis and Vascular Biology, 36(6), 1278-1285. https://doi.org/10.1161/ATVBAHA.115.306552

van der Leeuw, J., Beulens, J. W. J., van Dieren, S., Schalkwijk, C. G., Glatz, J. F. C., Hofker, M. H., Verschuren, W. M. M., Boer, J. M. A., van der Graaf, Y., Visseren, F. L. J., Peelen, L. M., & van der Schouw, Y. T. (2016). Novel Biomarkers to Improve the Prediction of Cardiovascular Event Risk in Type 2 Diabetes Mellitus. Journal of the American Heart Association, 5(6), Article e003048. https://doi.org/10.1161/JAHA.115.003048

van Twist, D. J. L., Houben, B., de Haan, M. W., de Leeuw, P. W., & Kroon, A. A. (2016). Renal hemodynamics and renin-angiotensin system activity in humans with multifocal renal artery fibromuscular dysplasia. Journal of Hypertension, 34(6), 1160-1169. https://doi.org/10.1097/HJH.0000000000000917

Gilsing, A. M. J., Weijenberg, M. P., Goldbohm, R. A., Dagnelie, P. C., van den Brandt, P. A., & Schouten, L. J. (2016). Vegetarianism, low meat consumption and the risk of lung, postmenopausal breast and prostate cancer in a population-based cohort study. European Journal of Clinical Nutrition, 70(6), 723-729. https://doi.org/10.1038/ejcn.2016.25

de Rooij, B. H., van der Berg, J. D., van der Kallen, C. J. H., Schram, M. T., Savelberg, H. H. C. M., Schaper, N. C., Dagnelie, P. C., Henry, R. M. A., Kroon, A. A., Stehouwer, C. D. A., & Koster, A. (2016). Physical Activity and Sedentary Behavior in Metabolically Healthy versus Unhealthy Obese and Non-Obese Individuals - The Maastricht Study. PLOS ONE, 11(5), Article e0154358. https://doi.org/10.1371/journal.pone.0154358

van Sloten, T. T., Mitchell, G. F., Sigurdsson, S., van Buchem, M. A., Jonsson, P. V., Garcia, M. E., Harris, T. B., Henry, R. M. A., Levey, A. S., Stehouwer, C. D. A., Gudnason, V., & Launer, L. J. (2016). Associations between arterial stiffness, depressive symptoms and cerebral small vessel disease: cross-sectional findings from the AGES-Reykjavik Study. Journal of Psychiatry & Neuroscience, 41(3), 162-168. https://doi.org/10.1503/jpn.140334

Martens, R., Kooman, J. P., Stehouwer, C. D. A., Dagnelie, P. C., van der Kallen, C. J. H., Koster, A., Kroon, A. A., Leunissen, K. M. L., Nijpels, G., van der Sande, F. M., Schaper, N. C., Sep, S. J. S., Verhey, F. R. J., van Boxtel, M. P. J., Schram, M. T., & Henry, R. M. A. (2016). ESTIMATED GLOMERULAR FILTRATION RATE, (MICRO) ALBUMINURIA AND COGNITIVE PERFORMANCE: THE MAASTRICHT STUDY. Nephrology Dialysis Transplantation, 31(S1), i192. https://doi.org/10.1093/ndt/gfw165.25

Nielen, J. T. H., Emans, P. J., Dagnelie, P. C., Boonen, A., Lalmohamed, A., de Boer, A., van den Bemt, B. J. F., & de Vries, F. (2016). Severity of Diabetes Mellitus and Total Hip or Knee Replacement A Population-Based Case-Control Study. Medicine, 95(20), Article e3739. https://doi.org/10.1097/MD.0000000000003739

Jahja, R., van Spronsen, F. J., de Sonneville, L. M. J., van der Meere, J. J., Bosch, A. M., Hollak, C. E. M., Rubio Gozalbo, E., Brouwers, M. C. G. J., Hofstede, F. C., de Vries, M. C., Janssen, M. C. H., van der Ploeg, A. T., Langendonk, J. G., & Huijbregts, S. C. J. (2016). Social-cognitive functioning and social skills in patients with early treated phenylketonuria: a PKU-COBESO study. Journal of Inherited Metabolic Disease, 39(3), 355-362. https://doi.org/10.1007/s10545-016-9918-0

Eussen, S. J. P. M., van Dongen, M., Wijckmans, N., den Biggelaar, L., Elferink, S. J. W. H. O., Singh-Povel, C. M., Schram, M. T., Sep, S. J. S., van der Kallen, C. J., Koster, A., Schaper, N., Henry, R. M. A., Stehouwer, C. D. A., & Dagnelie, P. C. (2016). Consumption of dairy foods in relation to impaired glucose metabolism and type 2 diabetes mellitus: the Maastricht Study. British Journal of Nutrition, 115(8), 1453-1461. https://doi.org/10.1017/S0007114516000313

van den Oever, I. A. M., van Sij, A. M., Baylan, U., ter Wee, M. M., Schalkwijk, C. G., Krijnen, P. A. J., Nurmohamed, M. T., Voskuyl, A. E., Niessen, H. W. M., & Simsek, S. (2016). Comparing inflammatory cell density in the myocardium and coronary arteries in rheumatoid arthritis patients versus controls with myocardial infarction: A post-mortem case-control study. International Journal of Cardiology, 209, 74-76. https://doi.org/10.1016/j.ijcard.2016.02.065

Cobussen, M., de Kort, J. M. L., Dennert, R. M., Lowe, S. H., & Stassen - Marx, P. (2016). No increased risk of acute kidney injury after a single dose of gentamicin in patients with sepsis. Infectious Diseases, 48(4), 274-280. https://doi.org/10.3109/23744235.2015.1109136

van der Berg, J. D., Stehouwer, C. D., Bosma, H., van der Velde, J. H., Willems, P., Savelberg, H. HCM., Schram, M. T., Sep, S., van der Kallen, C. J., Henry, R. M., Dagnelie, P. C., Schaper, N. C., & Koster, A. (2016). Associations of total amount and patterns of sedentary behaviour with type 2 diabetes and the metabolic syndrome: The Maastricht Study. Diabetologia, 59(4), 709-718. https://doi.org/10.1007/s00125-015-3861-8

Maessen, D. E., Brouwers, O., Gaens, K. H., Wouters, K., Cleutjens, J. P., Janssen, B. J., Miyata, T., Stehouwer, C. D., & Schalkwijk, C. G. (2016). Delayed Intervention With Pyridoxamine Improves Metabolic Function and Prevents Adipose Tissue Inflammation and Insulin Resistance in High-Fat Diet-Induced Obese Mice. Diabetes, 65(4), 956-966. https://doi.org/10.2337/db15-1390

Kimenai, D. M., Henry, R. M. A., van der Kallen, C. J. H., Dagnelie, P. C., Schram, M. T., Stehouwer, C. D. A., van Suijlen, J. D. E., Niens, M., Bekers, O., Sep, S. J. S., Schaper, N. C., van Dieijen-Visser, M. P., & Meex, S. J. R. (2016). Direct comparison of clinical decision limits for cardiac troponin T and I. Heart, 102(8), 610-616. https://doi.org/10.1136/heartjnl-2015-308917

Uiterwijk, R., Huijts, M., Staals, J., Rouhl, R. P. W., De Leeuw, P. W., Kroon, A. A., & Van Oostenbrugge, R. J. (2016). Endothelial Activation Is Associated With Cognitive Performance in Patients With Hypertension. American Journal of Hypertension, 29(4), 464-469. https://doi.org/10.1093/ajh/hpv122

BIOS Consortium, van Greevenbroek, M., Stehouwer, C., van der Kallen, C. J. H., & Schalkwijk, C. (2016). Genetic and environmental influences interact with age and sex in shaping the human methylome. Nature Communications, 7, Article 11115. https://doi.org/10.1038/ncomms11115

Fuijkschot, W. W., de Graaff, H. J., Berishvili, E., Kakabadze, Z., Kupreishvili, K., Meinster, E., Houtman, M., van Broekhoven, A., Schalkwijk, C. G., Vonk, A. B. A., Krijnen, P. A. J., Smulders, Y. M., & Niessen, H. W. N. (2016). Prevention of age-induced N(epsilon)-(carboxymethyl)lysine accumulation in the microvasculature. European Journal of Clinical Investigation, 46(4), 334-341. https://doi.org/10.1111/eci.12599

Koning, N. J., de lange, F., Vonk, A. B. A., Ahmed, Y., van den Brom, C. E., Bogaards, S., van Meurs, M., Jongman, R. M., Schalkwijk, C. G., Begieneman, M. P. V., Niessen, H. W., Baufreton, C., & Boer, C. (2016). Impaired microcirculatory perfusion in a rat model of cardiopulmonary bypass: the role of hemodilution. American Journal of Physiology-heart and Circulatory Physiology, 310(5), H550-H558. https://doi.org/10.1152/ajpheart.00913.2015

van Bussel, F. C. G., Backes, W. H., Hofman, P. A. M., van Boxtel, M. P. J., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. F. A. (2016). Altered Hippocampal White Matter Connectivity in Type 2 Diabetes Mellitus and Memory Decrements. Journal of Neuroendocrinology, 28(3), Article 12366. https://doi.org/10.1111/jne.12366

von Scholten, B. J., Reinhard, H., Hansen, T. W., Schalkwijk, C. G., Stehouwer, C., Parving, H.-H., Jacobsen, P. K., & Rossing, P. (2016). Markers of inflammation and endothelial dysfunction are associated with incident cardiovascular disease, all-cause mortality, and progression of coronary calcification in type 2 diabetic patients with microalbuminuria. Journal of Diabetes and Its Complications, 30(2), 248-255. https://doi.org/10.1016/j.jdiacomp.2015.11.005

Daemen, S., van Zandvoort, M. A. M. J., Parekh, S. H., & Hesselink, M. K. C. (2016). Microscopy tools for the investigation of intracellular lipid storage and dynamics. Molecular Metabolism, 5(3), 153-163. https://doi.org/10.1016/j.molmet.2015.12.005

Zuo, H., Ueland, P. M., Ulvik, A., Eussen, S. J. P. M., Vollset, S. E., Nygard, O., Midttun, O., Theofylaktopoulou, D., Meyer, K., & Tell, G. S. (2016). 9 Plasma Biomarkers of Inflammation, the Kynurenine Pathway, and Risks of All-Cause, Cancer, and Cardiovascular Disease Mortality. American Journal of Epidemiology, 183(4), 249-258. https://doi.org/10.1093/aje/kwv242

Hertle, E., Arts, I. C. W., van der Kallen, C. J. H., Feskens, E. J. M., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2016). The alternative complement pathway is longitudinally associated with adverse cardiovascular outcomes The CODAM study. Thrombosis and Haemostasis, 115(2), 446-457. https://doi.org/10.1160/TH15-05-0439

Nielen, J. T., de Vries, F., Dagnelie, P. C., van den Bemt, B. J., Emans, P. J., Lalmohamed, A., de Boer, A., & Boonen, A. E. (2016). Use of thiazolidinediones and the risk of elective hip or knee replacement: a population based case-control study. British Journal of Clinical Pharmacology, 81(2), 370-378. https://doi.org/10.1111/bcp.12786

van Dooren, F., Denollet, J., Verhey, F. R., Stehouwer, C. D., Sep, S., Henry, R., Kremers, S. P. J., Dagnelie, P. C., Schaper, N. C., van der Kallen, C. J., Koster, A., Pouwer, F., & Schram, M. T. (2016). Psychological and personality factors in type 2 diabetes mellitus, presenting the rationale and exploratory results from The Maastricht Study, a population-based cohort study. BMC Psychiatry, 16(1), Article 17. https://doi.org/10.1186/s12888-016-0722-z

Hollak, C. E. M., Biegstraaten, M., Baumgartner, M. R., Belmatoug, N., Bembi, B., Bosch, A., Brouwers, M., Dekker, H., Dobbelaere, D., Engelen, M., Groenendijk, M. C., Lachmann, R., Langendonk, J. G., Langeveld, M., Linthorst, G., Morava, E., Poll-The, B. T., Rahman, S., Rubio Gozalbo, E., ... Hagendijk, R. (2016). Position statement on the role of healthcare professionals, patient organizations and industry in European Reference Networks. Orphanet Journal of Rare Diseases, 11(1), Article 7. https://doi.org/10.1186/s13023-016-0383-5

Scheijen, J. L. J. M., Clevers, E., Engelen, L., Dagnelie, P. C., Brouns, F., Stehouwer, C. D. A., & Schalkwijk, C. G. (2016). Analysis of advanced glycation endproducts in selected food items by ultra-performance liquid chromatography tandem mass spectrometry: Presentation of a dietary AGE database. Food Chemistry, 190, 1145-1150. https://doi.org/10.1016/j.foodchem.2015.06.049

van Dooren, F., Verhey, F. R. J., Pouwer, F., Schalkwijk, C. G., Sep, S. J. S., Stehouwer, C. D. A., Henry, R. M. A., Dagnelie, P. C., Schaper, N. C., van der Kallen, C. J. H., Koster, A., Schram, M. T., & Denollet, J. (2016). Association of Type D personality with increased vulnerability to depression: is there a role for inflammation or endothelial dysfunction? - the Maastricht Study. Journal of Affective Disorders, 189, 118-125. https://doi.org/10.1016/j.jad.2015.09.028

Sanders, M. F., Blankestijn, P. J., Voskuil, M., Spiering, W., Vonken, E. J., Rotmans, J. I., van der Hoeven, B. L., Daemen, J., van den Meiracker, A. H., Kroon, A. A., de Haan, M. W., Das, M., Bax, M., van der Meer, I. M., van Overhagen, H., van den Born, B. J. H., van Brussel, P. M., van der Valk, P. H. M., Gregoor, P. J. H. S., ... Bots, M. L. (2016). Safety and long-term effects of renal denervation: Rationale and design of the Dutch registry. Netherlands Journal of Medicine, 74(1), 5-15.

van Sloten, T. T., & Stehouwer, C. D. A. (2016). Carotid Stiffness: A Novel Cerebrovascular Disease Risk Factor. Pulse, 4(1), 24-27. https://doi.org/10.1159/000445354

van Greevenbroek, M. M. J., Schalkwijk, C. G., & Stehouwer, C. D. A. (2016). Dysfunctional adipose tissue and low-grade inflammation in the management of the metabolic syndrome: current practices and future advances. F1000Research, 5, Article 2515. https://doi.org/10.12688/f1000research.8971.1

van der Heijden, R. A., Morrison, M. C., Sheedfar, F., Mulder, P., Schreurs, M., Hommelberg, P. P. H., Hofker, M. H., Schalkwijk, C., Kleemann, R., Tietge, U. J. F., Koonen, D. P. Y., & Heeringa, P. (2016). Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity. Mediators of Inflammation, 2016, Article 2042107. https://doi.org/10.1155/2016/2042107

van Dalem, J., Brouwers, M., Stehouwer, C., Krings, A., Leufkens, H. G. M., Driessen, J. H. M., de Vries, F., & Burden, A. (2016). Het risico op hypoglykemieën bij sulfonylureumderivaten ten opzichte van metformine in relatie tot nierfunctie en metabolietgroep. Nederlands Platform voor Farmaceutisch Onderzoek, 1, Article a1636. https://www.knmp.nl/professie/wetenschap/nederlands-platform-voor-farmaceutisch-onderzoek/het-risico-op-hypoglykemieen-bij-sulfonylureumderivaten-ten-opzichte-van-metformine-in-relatie-tot-nierfunctie-en-metabolietgroep

Potse, M., Lankveld, T. A. R., Zeemering, S., Dagnelie, P. C., Stehouwer, C. D. A., Henry, R. M., Linnenbank, A. C., Kuijpers, N. H. L., & Schotten, U. (2016). P-wave complexity in normal subjects and computer models. Journal of Electrocardiology, 49(4), 545-553. https://doi.org/10.1016/j.jelectrocard.2016.05.005

Alam, N., van de Ven, P. M., Oskam, E., Stassen, P., Kramer, M. H., Exter, P. V., & Nanayakkara, P. W. (2016). Study protocol for a Multi-centre, Investigator-initiated, Randomized Controlled Trial to Compare the Effects of Prehospital Antibiotic Treatment for Sepsis Patients with Usual Care after Training Emergency Medical Services (EMS) Personnel in Early Recognition (- The Prehospital ANTibiotics Against Sepsis (PHANTASi) trial. Acute Medicine, 15(4), 176-184. https://doi.org/10.52964/AMJA.0633

Huber, M., van Vliet, M., Giezenberg, M., Winkens, B., Heerkens, Y., Dagnelie, P. C., & Knottnerus, J. A. (2016). Towards a 'patient-centred' operationalisation of the new dynamic concept of health: a mixed methods study. BMJ Open, 5(1), Article e010091. https://doi.org/10.1136/bmjopen-2015-010091

Brouwers, M. C. G. J. (2015). Electrolyte and Acid-Base Disturbances in Diabetes Mellitus. New England Journal of Medicine, 373(25), 2482-2482.

Teunissen-Beekman, K. F. M., Dopheide, J., Geleijnse, J. M., Bakker, S. J., Brink, E. J., de Leeuw, P. W., Schalkwijk, C. G., & van Baak, M. A. (2015). Dietary proteins improve endothelial function under fasting conditions but not in the postprandial state, with no effects on markers of low-grade inflammation. British Journal of Nutrition, 114(11), 1819-1828. https://doi.org/10.1017/s0007114515003530

Magdelijns, F. J. H., Pijpers, E., Rouhl, R. P. W., Hannemann, P. F. W., ten Broeke, R. H. M., Dings, J. T. A., Stehouwer, C. D. A., & Stassen, P. M. (2015). Acute Hospital Admissions Because of Health Care-Related Adverse Events: A Retrospective Study of 5 Specialist Departments. Journal of the American Medical Directors Association, 16(12), 1055-1061. https://doi.org/10.1016/j.jamda.2015.06.019

Gaens, K. H. J., Ferreira, I., van de Waarenburg, M. P. H., van Greevenbroek, M. M., van der Kallen, C. J. H., Dekker, J. M., Nijpels, G., Rensen, S. S., Stehouwer, C. D. A., & Schalkwijk, C. G. (2015). Protein-Bound Plasma N-epsilon-(Carboxymethyl) lysine Is Inversely Associated With Central Obesity and Inflammation and Significantly Explain a Part of the Central Obesity-Related Increase in Inflammation The Hoorn and CODAM Studies. Arteriosclerosis Thrombosis and Vascular Biology, 35(12), 2707-2713. https://doi.org/10.1161/ATVBAHA.115.306106

Gijsbers, L., Dower, J. I., Schalkwijk, C. G., Kusters, Y. H. A. M., Bakker, S. J. L., Hollman, P. C. H., & Geleijnse, J. M. (2015). Effects of sodium and potassium supplementation on endothelial function: a fully controlled dietary intervention study. British Journal of Nutrition, 114(9), 1419-1426. https://doi.org/10.1017/S0007114515002986

van der Heijden, R. A., Bijzet, J., Meijers, W. C., Yakala, G. K., Kleemann, R., Nguyen, T. Q., de Boer, R. A., Schalkwijk, C. G., Hazenberg, B. P. C., Tietge, U. J. F., & Heeringa, P. (2015). Obesity-induced chronic inflammation in high fat diet challenged C57BL/6J mice is associated with acceleration of age-dependent renal amyloidosis. Scientific Reports, 5, Article 16474. https://doi.org/10.1038/srep16474

van Sloten, T. T., Sedaghat, S., Laurent, S., London, G. M., Pannier, B., Ikram, M. A., Kavousi, M., Mattace-Raso, F., Franco, O. H., Boutouyrie, P., & Stehouwer, C. D. A. (2015). Carotid Stiffness Is Associated With Incident Stroke A Systematic Review and Individual Participant Data Meta-Analysis. Journal of the American College of Cardiology, 66(19), 2116-2125. https://doi.org/10.1016/j.jacc.2015.08.888

Mbakwa, C. A., Penders, J., Savelkoul, P. H., Thijs, C., Dagnelie, P. C., Mommers, M., & Arts, I. C. W. (2015). Gut colonization with methanobrevibacter smithii is associated with childhood weight development. Obesity, 23(12), 2508-2516. https://doi.org/10.1002/oby.21266

Vossen, L. M., Schurgers, L. J., van Varik, B. J., Kietselaer, B. L. J. H., Vermeer, C., Meeder, J. G., Rahel, B. M., van Cauteren, Y. J. M., Hoffland, G. A., Rennenberg, R. J. M. W., Reesink, K. D., de Leeuw, P. W., & Kroon, A. A. (2015). Menaquinone-7 Supplementation to Reduce Vascular Calcification in Patients with Coronary Artery Disease: Rationale and Study Protocol (VitaK-CAC Trial). Nutrients, 7(11), 8905-8915. https://doi.org/10.3390/nu7115443

Legein, B., Janssen, E. M., Theelen, T. L., Gijbels, M. J., Walraven, J., Klarquist, J. S., Hennies, C. M., Wouters, K., Seijkens, T. T. P., Wijnands, E., Sluimer, J. C., Lutgens, E., Zenke, M., Hildner, K., Biessen, E. A. L., & Temmerman, L. (2015). Ablation of CD8 alpha(+) dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice. Scientific Reports, 5, Article 15414. https://doi.org/10.1038/srep15414

Alnima, T., de Leeuw, P. W., & Kroon, A. A. (2015). Baropacing as a new option for treatment of resistant hypertension. European Journal of Pharmacology, 763, 23-27. https://doi.org/10.1016/j.ejphar.2015.03.097