theses 2024

Carsten Arnoldussen
Supervisors: Prof. Joachim Wildberger, Dr Arina ten Cate-Hoek, Prof. Cees Wittens
Title: 'Utilization of MR-Venography in deep vein obstruction'
12 January

Karolien Baldewijns
Supervisor: Prof. Hans-Peter Brunner-La Rocca | Co-supervisors: Dr JJJ Boyne, Dr A Devillé (Thomas More University of Applied Scieces)
Title: 'From guideline to practise: The organisation of multidisciplinary heart failure care in three European regions'
25 January

Tim van Loon
Supervisors: Prof. Joost Lumens, Prof. Tammo Delhaas
Title: 'Fail to Fill: An in silico investigation of complex cardiac filling dynamics'
1 February

Renée Tillie
Supervisors: Prof. Judith Sluimer, Prof. Erik Biessen
Title: 'Plaque stabilizing and destabilizing effects in atherosclerosis: The role of microvessels, macrophage metabolism and fibroblasts'
2 February

Claudia van der Heijden
Supervisor: Prof. Jos Maessen | Co-supervisor: Dr Bart Maessen
Title: 'Exploring the Essential Aspects of the Hybrid Approach for Atrial Fibrillation'
2 February

Martine Bol
Supervisor: Prof. Tammo Delhaas
Co-supervisors: Dr M.C.G. van de Poll, Dr J.W.E.M. Sels
Title: 'Methodological and clinical aspects of glycocalyx measurements in critical illnes'
19 February

Job Stoks
Supervisors: Prof. Paul Volders, Prof. R.L.M. Peters, Prof. P. Dendale (Universiteit Hasselt) | Co-supervisor: Dr Matthijs Cluitmans
Title: 'Multimodal Image Integration to Better Explain Human Ventricular Tachyarrhythmias'
22 February

Narek Manukjan
Supervisors: Dr W.M. Blankesteijn, Prof. Z. Ahmed (University of Birmingham) | Co-supervisors: Dr S. Foulquier, Dr D. Fulton (University of Birmingham)
Title: 'White matter really matters in cerebral small vessel disease: Role of hypoxia signalling in oligodendrocyte precursor cells and its crosstalk with endothelial cells'
5 March

Chukiat Tantiwong
Supervisors: Prof. J.W.M. Heemskerk, Prof. J.M. Gibbins (University of Reading) | Co-supervisors: Dr R. Cavill. Dr J.L. Dunster (University of Reading)
Title: 'Modelling of collagen receptor clustering and signalling'
11 March

Rik Hendrix
Supervisor: Prof. J.G. Maessen | Co-supervisors: Dr P.W. Weerwind (Medanex Clinic/NAMSA Diest), Dr Y.M. Ganushchak (Erasmus University Rotterdam)
Title: 'The membrane oxygenator From a black to a white box'
12 March

Astrid Hermans
Supervisors: Prof. D. Linz, Prof. U. Schotten, Prof. K. Vernooy
Title: 'Detection and management of atrial fibrillation: state of art and novel approaches'
14 March

Jinmi Zou
Supervisors: Prof. H. ten Cate, Prof. J.W.M. Heemskerk
Co-supervisor: Dr F. Swieringa (Synapse Research Institute)
Title: 'Transient and persistent aspects of human platelet activation'
19 March

Daniëlle Kerkhofs
Supervisors: Prof. R.J. van Oostenbrugge, Prof. E.A Biessen | Co-supervisors: Dr J.E.A. Staals, Dr S. Foulquier
Title: 'Inflammatory cells and blood-brain barrier leakage in cerebral small vessel diseases'
21 March

Federica Jiritano
Supervisors: Prof. R. Lorusso, Prof. J.G. Maessen
Title: 'New insights about quantitative platelet disorders in the cardiac surgery and mechanical circulatory support settings'
22 March

Mathias Van Den Eynde
Supervisor: Prof. C.G. Schalkwijk | Co-supervisor: Dr A.J.H.M. Houben
Title: 'Intervention strategies in the glycation pathway with methylglyoxal as the primary target'
26 March

Miranda Bijvoet
Supervisors: Prof. K. Vernooy, Prof. R. Nijveldt (Radboud UMC Nijmegen) | Co-supervisors: Dr S.M. Chaldoupi, Dr C. Mihl
Title: 'The role of cardiac MRI in the treatment of patients with atrial arrhythmias'
11 April

Alejandro Pallares Robles
Supervisors: Prof. H. ten Cate, Prof. P. Wild (University Medical Center of Johannes Gutenberg University Mainz) | Co-supervisors: Dr A.J. ten Cate-Hoek, Dr V. ten Cate (University Medical Center of Johannes Gutenberg University Mainz)
Title: 'Multifaceted analysis of coagulant activity in venous thrombo-inflammation'
17 April

Ignazio Condello
Supervisors: Prof. R. Lorusso, Prof. J.G. Maessen | Co-supervisor: Dr G. Nasso (Anthea Hospital- GVM Care & Research Italy)
Title: 'Effects, Management and Optimization of Extracorporeal Techniques and Technologies in Contemporary Cardiac Surgery'
19 April

Pengyu Zhang - double degree
Supervisors: Prof. J.W.M. Heemskerk, Prof. U. Walter (Johannes Gutenberg University Mainz) | Co-supervisors: Dr M.J.E. Kuijpers, Dr K. Jurk (Johannes Gutenberg University Mainz)
Title: 'Multisite phosphorylation in platelets stimulated via glycoprotein VI and G protein-coupled receptors: Interactions and functional impact'
6 June

Magdi Beran
Supervisors: Dr M.T. Schram, Dr M.I. Geerlings (Amsterdam UMC) | Co-supervisors: Dr T.T. van Sloten (UMC Utrecht), Dr J.M.J. Vonk (University of California, San Francisco)
Title: 'Aetiology of dementia and depression: Untangling the role of biomarkers and sociodemographic factors'
7 June

Gaukhar Baidildinova - double degree
Supervisors: Prof. H. ten Cate, Prof. P.S. Wild (Johannes Gutenberg University Mainz) | Co-supervisors: Dr H.M.H. Spronk, Dr K. Jurk (Johannes Gutenberg University Mainz)
Title: 'Platelet functional signatures in venous and arterial thrombotic diseases'
11 June

Anneloes Munneke
Supervisors: Prof. T. Delhaas, Prof. J. Lumens | Co-supervisor: Em.Prof. T. Arts
Title: 'Lifelines of Life: Diving into Fetal and Coronary Circulations using Computational Models'
20 June

Babs Hendriks
Supervisor: Prof. J.E. Wildberger | Co-supervisors: Dr B. Martens, Prof. M. Das (Helios Hospital Duisburg)
Title: 'Personalised CT Scan Protocols for the Detection of Pulmonary Embolism'
21 June 

Balázs Erdos
Supervisor: Prof. I.C.W. Arts | Co-supervisors: Dr M. Adriaens
Title: 'Quantifying Metabolic Health form High Dimensional Post-Meal Dynamics'
1 July

Martin Martinek
Supervisors: Prof. H.J.G.M. Crijns, Prof. G.J. Pruckner (Institute of Health Economics, Linz) | Co-supervisors: B.A.B. Essers
Title: 'Contemporary atrial fibrillation management: healthcare expenditures, treatment methods, and outcomes'
1 July

Nasim Bahram Sangani
Supervisors: Prof. C.P. Reutelingspergers, Prof. L.J. Schurgers | Co-supervisors: Prof. L.M.G. Curfs, Dr L.M.T. Eijssen
Title: 'The molecular signature of Rett syndrome'
2 July

Mitch Ramaekers
Supervisors: Prof. J.E. Wildberger, Prof. H.J Lamb (LUMC) | Co-supervisors: Dr S. Schalla, Dr.ir J. Westenberg (LUMC)
Title: 'Unraveling aortic flow dynamics with MRI: The fine line between normal and abnormal'
5 September

Linsey Peters
Supervisors: Prof. E.A.L Biessen, Prof. J. Jankowski | Co-supervisor: Dr E.P.C. van der Vorst (RWTH Aachen University)
Title: 'MicroRNA-26b plays a major regulatory role in cardiometabolic diseases'
13 September

Akhil Antony Konkoth
Supervisors: Prof. R.R. Koenen, Prof. T.M. Hackeng, Prof. R. Lacroix (Aix Mairseille University, France)
Title: 'Multifaceted Role of Microvesicles in Thrombo-inflammation: Role of Microvesicles in Haemostatic Imbalance in Sepsis'
16 September

Mohammed Ghossein
Supervisors: Prof. K. Vernooy, Prof. F.W. Prinzen | Co-supervisors: Dr A.M.W. van Stipdonk, Dr B.C.T. van Bussel
Title: 'Exploring QRS area to improve cardiac resynchronization therapy & intensive care monitoring'
18 September

Arno Gingele
Supervisor:  Prof. Hans-Peter Brunner-La Rocca | Co-supervisors: Dr Josiane Boyne, Dr Christian Knackstedt
Title: 'Towards a holistic eHealth product for heart failure management - a road map'
7 October

Eline Berends
Supervisors: Prof. Casper Schalkwijk, Prof. Robert van Oostenbrugge | Co-supervisor: Dr Sébastien Foulquier
Title: 'Methylglyoxal and the brain microcirculation: The source matters'
10 October

April van Gennep
Supervisor: Prof. Bastiaan de Galan
Co-supervisor: Dr Thomas van Sloten (UMC Utrecht)
Title: 'Dementia and depression: Risk factors and microvascular mechanisms'
10 October

Max Meertens
Supervisors: Prof. Barend Mees, Prof. Geert-Willem Schurink
Title: 'Arterial access in endovascular procedures for vascular pathologies'
15 October

Shaiv Parikh
Supervisor: Prof. Tammo Delhaas | Co-supervisors: Dr.ir Koen D. Reesink, Dr.ir Wouter Huberts (TU/e), Dr Elham Bidar
Title: 'Investigating the Biological and Physical Complexities of Ascending Thoracic Aortic Aneurysms'
1 November

Maria Martha Suverein
Supervisors: Prof. Jos Maessen, Prof. Roberto Lorusso | Co-supervisors: Dr Marcel van de Poll
Title: 'Clinical Effectiveness of Extracorporeal Cardiopulmonary Resuscitation in Out-of-hospital Cardiac Arrest'
4 November

Kailiang Zheng
Supervisor: Prof. J.M. ten Berg | Co-supervisors: Dr P.G. Noordzij (St. Antonius Ziekenhuis) Dr C.M. Hackeng (St. Antonius Ziekenhuis)
Title: 'Antithrombotic therapy, platelet reactivity and post-operative myocardial injury'
7 November

Maud van Dinther
Supervisors: Prof. J.E.A. Staals, Prof. R.J. van Oostenbrugge, Prof. W.H. Backes
Title: 'Cerebral Small Vessel Disease: Imaging Insights in the Pathohysiological Processes of the Neurovascular Unit & Multisystem Involvement'
8 November

Tobias Michiel Hommels
Supervisors: Prof. A.W.J. van ’t Hof, Prof. E. Kedhi, McGill (University Health Center Montreal) | Co-supervisor: Dr R.S. Hermanides (Isala Zwolle)
Title: 'Challenges of Diabetes Mellitus and Percutaneous Treatment in Modern Interventional Cardiology'
12 November

Giulia Spanò
Supervisors: Prof. Leon J. de Windt, Prof. Monika Stoll, 
Title: 'm6A mosaics, transcriptional regulation of developing cardiomyocytes'
13 November

Koen van der Laan
Supervisor: Prof. T. Delhaas | Co-supervisors: Dr.ir K.D. Reesink, Dr.ir B. Spronck 
Title: 'An ex vivo experimental approach for connecting the multiple facets of arterial stiffening'
21 November

Rudolf Theodoor Tolsma
Supervisor: Prof. A.W.J. van ’t Hof | Co-supervisors: Dr J.P. Ottervanger (Isala Zwolle), Dr R.J. Slingerland, (Isala Zwolle)
Title: 'Prehospital management of patients suspected for non ST-elevation acute coronary syndrome'
22 November

Syed Muhammed Mueez Aizaz
Supervisors: Prof. M. E. Kooi, Prof. R. M. Botnar (King’s College London), Prof. F. M. Mottaghy (RWTH Aachen University) | Co-supervisors: Dr.ir R. P. M. Moonen 
Title: 'Advanced Non-invasive Atherosclerotic Plaque Imaging Strategies: Harnessing the Power of MRI, PET-MRI and Dual Energy CT'
26 November

David Barnett
Supervisors: Prof.ir. I. Arts, Prof. J. Penders
Title: 'Perturbing and protecting the infant gut: exploring the impacts of antibiotics and oligosaccharides on gut microbiota and child health'
5 December

Michael Brunner
Supervisors: Prof. A. zur Hausen, Prof. J. Sluimer
Title: 'Development and usefulness of transgenic rabbit models of inborn arrhythmogenic diseases'
9 December

Shengshi Huang
Supervisor: Prof. H. ten Cate | Co-supervisors: Dr B. de Laat (Synapse Institute), Dr M. Ninivaggi (Synapse Institute)
Title: 'The Molecular Linkage of von Willebrand Factor (VWF) and Pathological Coagulation in Disease'
12 December

Borek Foldyna
Supervisor: Prof.ir. H. Aerts | Co-supervisor: Dr M. Lu (Harvard Medical School)
Title: 'Artificial Intelligence in Cardiac Imaging: Assessment, Prediction, and Management of Cardiovascular Risk'
12 December

Deepak Balamurali
Supervisor: Prof. M. Stoll | Co-supervisor: Dr A. Isaacs
Title: 'The dark side of the Genome A story in three-peats’
13 December

Fang Wang
Supervisor: Prof. J. Glatz | Co-supervisors: Dr J. Luiken, Dr M. Nabben, Dr D. Neumann
Title: 'Targeting CD36 and v-ATPase for diabetic cardiomyopathy treatment'
18 December

Rawan Alnazer
Supervisors: Prof. A. Kroon, Prof. P. de Leeuw
Title: 'The factors influencing renin, aldosterone, and the aldosterone-to-renin ratio'
19 December

Gregory Veldhuizen
Supervisors: Prof. A. Kroon, Prof. P. de Leeuw
Title: 'The factors influencing renin, aldosterone, and the aldosterone-to-renin ratio'
19 December