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CARIM's Confidential Contact Persons

CARIM's Confidential Contact Persons

27 November 2024

Dr Magdi Nagy (Dept of Biochemistry) and Prof. Peter de Leeuw (Dept of Internal Medicine) have been appointed as CARIM Confidential Contact Persons.

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ZonMw grant on appropriate palliative care

ZonMw grant on appropriate palliative care

27 November 2024

Prof. Marc Hemmelder (Dept of Internal Medicine) and his team received a ZonMw grant to promote early palliative care for dialysis patients who are non-waitlisted for transplantation.

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Carim Maastricht
Carim Maastricht

Joachim Wildberger

Professor

Joachim Wildberger is full Professor of Radiology and Chairman of the Department of Radiology and Nuclear Medicine at Maastricht UMC+. In addition, he serves as Director of the Division of Clinical Imaging and Diagnostic Laboratories at Maastrcith UMC+.

Graduated at the Rhenian-Westphalian Technical University (RWTH) in Aachen, Germany, he received his medical degree in 1994. After internships in Cardiology and Diagnostic Radiology (Mönchengladbach/ Leipzig), he started his residency in Diagnostic Radiology at the University Hospital Aachen. He was board certified for Diagnostic Radiology in December 1998, and became a fellow/staff member at this department thereafter. He received his PhD in Radiology in 2002, was appointed as vice-chairman of the department in 2006 and received a professorship at the RWTH Aachen in 2007. In July 2007 he became Head of Department, Diagnostic Radiology, HELIOS Klinikum Berlin-Buch, Charité Berlin, Campus Buch, Germany, before moving to his present position.

His per personal research topics are technical developments and functional imaging in computed tomography, contrast media research, cardiac imaging as well as image-guided interventions.

As PI for Imaging within CARIM he focusses on translational research, integrating different imaging modalities into the cardiovascular diagnostic chain, and favours multidisciplinary approaches to improve patient care.

Joachim-wildberger

Department of Radiology and Nuclear Medicine
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: 4.G2.013
T: +31(0)43 387 49 12

  • 2018
    • Eijsvoogel, N. G., Hendriks, B. M. F., Park, H. B., Altintas, S., Mihl, C., Horehledova, B., Kietselaer, B. L. J. H., Crijns, H. J. G. M., Wildberger, J. E., & Das, M. (2018). The role of standard non-ECG gated chest CT in cardiac assessment: design and rationale of the Cardiac Pathologies in standard chest CT (CaPaCT) study. European Radiology Experimental, 2(1), 1-5. https://doi.org/10.1186/s41747-018-0039-4
  • 2017
    • Jaarsma, C., Vink, H., van Haare, J., Bekkers, S. C. A. M., van Rooijen, B. D., Backes, W. H., Wildberger, J. E., Crijns, H. J., van Teeffelen, J., & Schalla, S. (2017). Non-invasive assessment of microvascular dysfunction in patients with microvascular angina. International Journal of Cardiology, 248, 433-439. https://doi.org/10.1016/j.ijcard.2017.05.010
    • Arnoldussen, C. W. K. P., Lam, Y., Ito, N., Winkens, B., Kooi, M. E., Wittens, C. H. A., & Wildberger, J. E. (2017). Gadobutrol versus gadofosveset-trisodium in MR venography of the lower extremities. European Radiology, 27(12), 4986-4994. https://doi.org/10.1007/s00330-017-4902-0
    • Lambin, P., Leijenaar, R. T. H., Deist, T. M., Peerlings, J., de Jong, E. E. C., van Timmeren, J., Sanduleanu, S., Larue, R. T. H. M., Even, A. J. G., Jochems, A., van Wijk, Y., Woodruff, H., van Soest, J., Lustberg, T., Roelofs, E., van Elmpt, W., Dekker, A., Mottaghy, F. M., Wildberger, J. E., & Walsh, S. (2017). Radiomics: the bridge between medical imaging and personalized medicine. Nature Reviews Clinical Oncology, 14(12), 749-762. https://doi.org/10.1038/nrclinonc.2017.141
    • Schnerr, R. S., Jansen, J. F. A., Uludag, K., Hofman, P. A. M., Wildberger, J. E., van Oostenbrugge, R. J., & Backes, W. H. (2017). Pulsatility of Lenticulostriate Arteries Assessed by 7 Tesla Flow MRI: Measurement, Reproducibility, and Applicability to Aging Effect. Frontiers in physiology, 8(NOV), Article 961. https://doi.org/10.3389/fphys.2017.00961
    • Boswijk, E., Bauwens, M., Mottaghy, F. M., Wildberger, J. E., & Bucerius, J. (2017). Potential of alpha 7 nicotinic acetylcholine receptor PET imaging in atherosclerosis. Methods, 130, 90-104. https://doi.org/10.1016/j.ymeth.2017.06.008
    • Sailer, A. M., Vergoossen, L., Paulis, L., van Zwam, W. H., Das, M., Wildberger, J. E., & Jeukens, C. R. L. P. N. (2017). Personalized Feedback on Staff Dose in Fluoroscopy-Guided Interventions: A New Era in Radiation Dose Monitoring. Cardiovascular and Interventional Radiology, 40(11), 1756-1762. https://doi.org/10.1007/s00270-017-1690-5
    • Pelgrim, G. J., Das, M., van Tuijl, S., van Assen, M., Prinzen, F. W., Stijnen, M., Oudkerk, M., Wildberger, J. E., & Vliegenthart, R. (2017). Validation of myocardial perfusion quantification by dynamic CT in an ex-vivo porcine heart model. International Journal of Cardiovascular Imaging, 33(11), 1821-1830. https://doi.org/10.1007/s10554-017-1171-6
    • Goorts, B., Voo, S., van Nijnatten, T. J. A., Kooreman, L. F. S., de Boer, M., Keymeulen, K. B. M. I., Aarnoutse, R., Wildberger, J. E., Mottaghy, F. M., Lobbes, M. B. I., & Smidt, M. L. (2017). Hybrid 18-FDG PET/MRI might improve locoregional staging of breast cancer patients prior to neoadjuvant chemotherapy. European Journal of Nuclear Medicine and Molecular Imaging, 44(11), 1796-1805. https://doi.org/10.1007/s00259-017-3745-x
    • van Hoof, R. H. M., Voo, S. A., Sluimer, J. C., Wijnen, N. J. A., Hermeling, E., Schreuder, F. H. B. M., Truijman, M. T. B., Cleutjens, J. P. M., Daemen, M. J. A. P., Daemen, J.-W. H., van Oostenbrugge, R. J., Mess, W. H., Wildberger, J. E., Heeneman, S., & Kooi, M. E. (2017). Vessel Wall and Adventitial DCE-MRI Parameters Demonstrate Similar Correlations With Carotid Plaque Microvasculature on Histology. Journal of Magnetic Resonance Imaging, 46(4), 1053-1059. https://doi.org/10.1002/jmri.25648
    • Smulders, M. W., Jaarsma, C., Nelemans, P. J., Bekkers, S. C. A. M., Bucerius, J., Leiner, T., Crijns, H. J. G. M., Wildberger, J. E., & Schalla, S. (2017). Comparison of the prognostic value of negative non-invasive cardiac investigations in patients with suspected or known coronary artery disease-ameta-analysis. European Heart Journal Cardiovascular Imaging, 18(9), 980-987. https://doi.org/10.1093/ehjci/jex014
    • Houben, I. P. L., Van de Voorde, P., Jeukens, C. R. L. P. N., Wildberger, J. E., Kooreman, L. F., Smidt, M. L., & Lobbes, M. B. I. (2017). Contrast-enhanced spectral mammography as work-up tool in patients recalled from breast cancer screening has low risks and might hold clinical benefits. European Journal of Radiology, 94, 31-37. https://doi.org/10.1016/j.ejrad.2017.07.004
    • Nijssen, E. C., Nelemans, P. J., Rennenberg, R. J., van Ommen, V., Wildberger, J. E., & CIN Grp MUMC (2017). Hydration and contrast-induced kidney injury: Author's reply. Lancet, 390(10093), 454-455. https://doi.org/10.1016/S0140-6736(17)31809-3
    • Bucerius, J., Barthel, H., Tiepolt, S., Werner, P., Sluimer, J. C., Wildberger, J. E., Patt, M., Hesse, S., Gertz, H.-J., Biessen, E. A. L., Mottaghy, F. M., & Sabri, O. (2017). Feasibility of in vivo (18)F-florbetaben PET/MR imaging of human carotid amyloid-beta. European Journal of Nuclear Medicine and Molecular Imaging, 44(7), 1119-1128. https://doi.org/10.1007/s00259-017-3651-2
    • Nijssen, E. C., Nelemans, P. J., Rennenberg, R. J., Essers, B. A., Janssen, M. M., Vermeeren, M. A., van Ommen, V., & Wildberger, J. E. (2017). Intravenous hydration according to current guidelines in the prevention of contrast induced nephropathy-the AMACING trial. Journal of Thoracic Disease, 9(7), E656-E657. https://doi.org/10.21037/jtd.2017.06.80
    • van Hoof, R. H. M., Hermeling, E., Sluimer, J. C., Salzmann, J., Hoeks, A. P. G., Roussel, J., Daemen, M. J. A. P., Struijker-Boudier, H., Wildberger, J. E., Heeneman, S., & Kooi, M. E. (2017). Heart rate lowering treatment leads to a reduction in vulnerable plaque features in atherosclerotic rabbits. PLOS ONE, 12(6), Article 0179024. https://doi.org/10.1371/journal.pone.0179024
    • Altintas, S., Dinh, T., Marcks, N. G. H. M., Kok, M., Aerts, A. J. J., Weijs, B., Blaauw, Y., Wildberger, J. E., Das, M., Kietselaer, B. L. J. H., & Crijns, H. J. G. M. (2017). Presence and extent of cardiac computed tomography angiography defined coronary artery disease in patients presenting with syncope. Netherlands Heart Journal, 25(6), 376-387. https://doi.org/10.1007/s12471-017-0970-7
    • van Bussel, F. C. G., Backes, W. H., Hofman, P. A. M., van Oostenbrugge, R. J., van Boxtel, M. P. J., Verhey, F. R. J., Steinbusch, H. W. M., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. JFA. (2017). Cerebral pathology and cognition in diabetes: the merits of multiparametric neuroimaging. Frontiers in Neuroscience, 11(APR), Article 188. https://doi.org/10.3389/fnins.2017.00188
    • Nijssen, E. C., Rennenberg, R. J., Nelemans, P. J., Essers, B. A., Janssen, M. M., Vermeeren, M. A., van Ommen, V., & Wildberger, J. E. (2017). Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial. Lancet, 389(10076), 1312-1322. https://doi.org/10.1016/S0140-6736(17)30057-0
    • Mihl, C., Maas, M., Turek, J., Seehofnerova, A., Leijenaar, R. T. H., Kok, M., Lobbes, M. B. I., Wildberger, J. E., & Das, M. (2017). Contrast Media Administration in Coronary Computed Tomography Angiography - A Systematic Review. RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der Bildgebenden Verfahren, 189(4), 312-325. https://doi.org/10.1055/s-0042-121609
    • Das, M., & Wildberger, J. E. (2017). Diagnostik der akuten Lungenembolie: Ein Update. Gefässchirurgie, 22(2), 135-147. https://doi.org/10.1007/s00772-017-0257-8
    • Sailer, A. M., Paulis, L., Vergoossen, L., Kovac, A. O., Wijnhoven, G., Schurink, G. W. H., Mees, B., Das, M., Wildberger, J. E., de Haan, M. W., & Jeukens, C. R. L. P. N. (2017). Real-Time Patient and Staff Radiation Dose Monitoring in IR Practice. Cardiovascular and Interventional Radiology, 40(3), 421-429. https://doi.org/10.1007/s00270-016-1526-8
    • van Bussel, F. C. G., Backes, W. H., van Veenendaal, T. M., Hofman, P. A. M., van Boxtel, M. P. J., Schram, M. T., Sep, S. J. S., Dagnelie, P. C., Schaper, N., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. F. A. (2017). Erratum: Functional Brain Networks Are Altered in Type 2 Diabetes and Prediabetes: Signs for Compensation of Cognitive Decrements? The Maastricht Study (vol 65, pg 2404, 2016). Diabetes, 66(2), 560. https://doi.org/10.2337/db17-er02a
    • Lindeboom, L., Bruls, Y. M. H., van Ewijk, P. A., Hesselink, M. K. C., Wildberger, J. E., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2017). Longitudinal relaxation time editing for acetylcarnitine detection with H-MRS. Magnetic Resonance in Medicine, 77(2), 505–510. https://doi.org/10.1002/mrm.26149
    • Houben, I. P. L., van Berlo, C. J. L. Y., Bekers, O., Nijssen, E. C., Lobbes, M. B. I., & Wildberger, J. E. (2017). Assessing the Risk of Contrast-Induced Nephropathy Using a Finger Stick Analysis in Recalls from Breast Screening: The CINFIBS Explorative Study. Contrast Media & Molecular Imaging, Article 5670384. https://doi.org/10.1155/2017/5670384
    • van Hoof, R. H. M., Schreuder, F. H. B. M., Nelemans, P., Truijman, M. T. B., van Orshoven, N. P., Schreuder, T. H., Mess, W. H., Heeneman, S., van Oostenbrugge, R. J., Wildberger, J. E., & Kooi, M. E. (2017). Ischemic Stroke Patients Demonstrate Increased Carotid Plaque Microvasculature Compared to (Ocular) Transient Ischemic Attack Patients. Cerebrovascular Diseases, 44(5-6), 297-303. https://doi.org/10.1159/000481146
  • 2016
    • Jansen, J., van Bussel, F. C. G., van de Haar, H. J., van Osch, M. J. P., Hofman, P. A. M., van Boxtel, M. P. J., van Oostenbrugge, R. J., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Backes, W. H. (2016). Cerebral blood flow, blood supply, and cognition in Type 2 Diabetes Mellitus. Scientific Reports, 6(1), Article 10. https://doi.org/10.1038/s41598-016-0003-6
    • Lalji, U. C., Houben, I. P. L., Prevos, R., Gommers, S., van Goethem, M., Vanwetswinkel, S., Pijnappel, R., Steeman, R., Frotscher, C., Mok, W., Nelemans, P., Smidt, M. L., Beets-Tan, R. G., Wildberger, J. E., & Lobbes, M. B. I. (2016). Contrast-enhanced spectral mammography in recalls from the Dutch breast cancer screening program: validation of results in a large multireader, multicase study. European Radiology, 26(12), 4371-4379. https://doi.org/10.1007/s00330-016-4336-0
    • Kok, M., Mihl, C., Hendriks, B. M. F., Altintas, S., Eijsvoogel, N. G., Kietselaer, B. L. J. H., Wildberger, J. E., & Das, M. (2016). Patient Comfort During Contrast Media Injection in Coronary Computed Tomographic Angiography Using Varying Contrast Media Concentrations and Flow Rates Results From the EICAR Trial. Investigative Radiology, 51(12), 810-815. https://doi.org/10.1097/RLI.0000000000000284
    • van Bussel, F. C. G., Backes, W. H., Hofman, P. A. M., Puts, N. A. J., Edden, R. A. E., van Boxtel, M. P. J., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. (2016). Increased GABA concentrations in type 2 diabetes mellitus are related to lower cognitive functioning. Medicine, 95(36), Article e4803. https://doi.org/10.1097/MD.0000000000004803
    • Lindeboom, L., de Graaf, R. A., Nabuurs, C. I., van Ewijk, E., Hesselink, M. K. C., Wildberger, J. E., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2016). Quantum coherence spectroscopy to measure dietary fat retention in the liver. JCI INSIGHT, 1(13), Article e84671. https://doi.org/10.1172/jci.insight.84671
    • van Bussel, F. C. G., Backes, W. H., van Veenendaal, T. M., Hofman, P. A. M., van Boxtel, M. P. J., Schram, M. T., Sep, S. J. S., Dagnelie, P. C., Schaper, N., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. (2016). Functional brain networks are altered in type 2 diabetes and pre-diabetes signs for compensation of cognitive decrements? - The Maastricht Study: signs for compensation of cognitive decrements? - The Maastricht Study. Diabetes, 65(8), 2404-2413. https://doi.org/10.2337/db16-0128
    • Kok, M., Turek, J., Mihl, C., Reinartz, S. D., Gohmann, R. F., Nijssen, E. C., Kats, S., van Ommen, V. G. V. A., Kietselaer, B. L. J. H., Wildberger, J. E., & Das, M. (2016). Low contrast media volume in pre-TAVI CT examinations. European Radiology, 26(8), 2426-2435. https://doi.org/10.1007/s00330-015-4080-x
    • Smulders, M. W., Kietselaer, B. L. J. H., Schalla, S., Bucerius, J., Jaarsma, C., van Dieijen-Visser, M. P., Mingels, A. M. A., Brunner-La Rocca, H., Post, M., Das, M., Crijns, H. J. G. M., Wildberger, J. E., & Bekkers, B. (2016). Acute chest pain in the high-sensitivity cardiac troponin era: A changing role for noninvasive imaging?American Heart Journal, 177, 102-111. https://doi.org/10.1016/j.ahj.2016.03.025
    • Das, M., & Wildberger, J. E. (2016). Diagnostik der akuten Lungenembolie. Der Radiologe, 56(6), 543-554. https://doi.org/10.1007/s00117-016-0100-3
    • van Hoof, R. H. M., Heeneman, S., Wildberger, J. E., & Kooi, E. (2016). Dynamic Contrast-Enhanced MRI to Study Atherosclerotic Plaque Microvasculature. Current Atherosclerosis Reports, 18(6), Article 33. https://doi.org/10.1007/s11883-016-0583-4
    • Kok, M., Mihl, C., Hendriks, B. M. F., Altintas, S., Kietselaer, B. L. J. H., Wildberger, J. E., & Das, M. (2016). Optimizing contrast media application in coronary CT angiography at lower tube voltage: Evaluation in a circulation phantom and sixty patients. European Journal of Radiology, 85(6), 1068-1074. https://doi.org/10.1016/j.ejrad.2016.03.022
    • Cardinaels, E. P. M., Altintas, S., Versteylen, M. O., Joosen, I. A., Jellema, L.-J. C., Wildberger, J. E., Das, M., Crijns, H. J., Bekers, O., van Dieijen-Visser, M. P., Kietselaer, B. L., & Mingels, A. M. A. (2016). High-Sensitivity Cardiac Troponin Concentrations in Patients with Chest Discomfort: Is It the Heart or the Kidneys As Well?PLOS ONE, 11(4), Article e0153300. https://doi.org/10.1371/journal.pone.0153300
    • Kemerink, G. J., van Engelshoven, J., Simon, K. J., Kutterer, G., & Wildberger, J. E. (2016). Early X-ray workers: an effort to assess their numbers, risk, and most common (skin) affliction. Insights into Imaging, 7(2), 275-282. https://doi.org/10.1007/s13244-015-0457-2
    • Mihl, C., Kok, M., Altintas, S., Kietselaer, B. L. J. H., Turek, J., Wildberger, J. E., & Das, M. (2016). Evaluation of individually body weight adapted contrast media injection in coronary CT-angiography. European Journal of Radiology, 85(4), 830-836. https://doi.org/10.1016/j.ejrad.2015.12.031
    • Kok, M., de Haan, M., Mihl, C., Eijsvoogel, N. G., Hendriks, B. M. F., Sailer, A. M., Derks, K., Schnerr, R. S., Schurink, G., Wildberger, J. E., & Das, M. (2016). Individualized CT Angiography Protocols for the Evaluation of the Aorta: A Feasibility Study. Journal of Vascular and Interventional Radiology, 27(4), 531-538. https://doi.org/10.1016/j.jvir.2016.01.009
    • van Bussel, F. C. G., Backes, W. H., Hofman, P. A. M., van Boxtel, M. P. J., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. F. A. (2016). Altered Hippocampal White Matter Connectivity in Type 2 Diabetes Mellitus and Memory Decrements. Journal of Neuroendocrinology, 28(3), Article 12366. https://doi.org/10.1111/jne.12366
    • van Elmpt, W., Zegers, K., Reymen, B., Even, A. J. G., Dingemans, A.-M. C., Öllers, M., Wildberger, J. E., Mottaghy, F. M., Das, M., Troost, E. G. C., & Lambin, P. (2016). Multiparametric imaging of patient and tumour heterogeneity in non-small-cell lung cancer: quantification of tumour hypoxia, metabolism and perfusion. European Journal of Nuclear Medicine and Molecular Imaging, 43(2), 240-248. https://doi.org/10.1007/s00259-015-3169-4
    • Landry, G., Gaudreault, M., van Elmpt, W., Wildberger, J. E., & Verhaegen, F. (2016). Improved dose calculation accuracy for low energy brachytherapy by optimizing dual energy CT imaging protocols for noise reduction using sinogram affirmed iterative reconstruction. Zeitschrift für Medizinische Physik, 26(1), 75-87. https://doi.org/10.1016/j.zemedi.2015.09.001
    • Hendriks, B. M. F., Kok, M., Mihl, C., Bekkers, B., Wildberger, J. E., & Das, M. (2016). Individually tailored contrast enhancement in CT pulmonary angiography. British Journal of Radiology, 89(1061), Article 20150850. https://doi.org/10.1259/bjr.20150850
    • Altintas, S., Cardinaels, E., Versteylen, M. O., Joosen, I. A., Seifert, H., Wildberger, J. E., Crijns, H. J., Nelemans, P. J., van Dieijen - Visser, M. P., Mingels, A. M. A., Das, M., & Kietselaer, B. L. (2016). Unstable coronary plaque characteristics are associated with high sensitivity cardiac troponin T and N-terminal Pro-Brain Natriuretic Peptide. Journal of Cardiovascular Computed Tomography, 10(1), 82-88. https://doi.org/10.1016/j.jcct.2015.10.001
  • 2015
    • Kok, M., Mihl, C., Seehofnerova, A., Turek, J., Jost, G., Pietsch, H., Haberland, U., Wildberger, J. E., & Das, M. (2015). Automated Tube Voltage Selection for Radiation Dose Reduction in CT Angiography Using Different Contrast Media Concentrations and a Constant Iodine Delivery Rate. American Journal of Roentgenology, 205(6), 1332-1338. https://doi.org/10.2214/AJR.14.13957
    • Sailer, A. M., van Zwam, W. H., Wildberger, J. E., & Grutters, J. P. C. (2015). Cost-effectiveness modelling in diagnostic imaging: a stepwise approach. European Radiology, 25(12), 3629-3637. https://doi.org/10.1007/s00330-015-3770-8
    • Lalji, U. C., Wildberger, J. E., Hausen, A. Z., Bendek, M., Dingemans, A.-M. C., Hochstenbag, M., & Das, M. (2015). CT-Guided Percutaneous Transthoracic Needle Biopsies Using 10G Large-Core Needles: Initial Experience. Cardiovascular and Interventional Radiology, 38(6), 1603-1610. https://doi.org/10.1007/s00270-015-1098-z
Overview