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CARIM's Confidential Contact Persons

CARIM's Confidential Contact Persons

27 November 2024

Dr Magdi Nagy (Dept of Biochemistry) and Prof. Peter de Leeuw (Dept of Internal Medicine) have been appointed as CARIM Confidential Contact Persons.

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ZonMw grant on appropriate palliative care

ZonMw grant on appropriate palliative care

27 November 2024

Prof. Marc Hemmelder (Dept of Internal Medicine) and his team received a ZonMw grant to promote early palliative care for dialysis patients who are non-waitlisted for transplantation.

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Carim Maastricht
Carim Maastricht

Joachim Wildberger

Professor

Joachim Wildberger is full Professor of Radiology and Chairman of the Department of Radiology and Nuclear Medicine at Maastricht UMC+. In addition, he serves as Director of the Division of Clinical Imaging and Diagnostic Laboratories at Maastrcith UMC+.

Graduated at the Rhenian-Westphalian Technical University (RWTH) in Aachen, Germany, he received his medical degree in 1994. After internships in Cardiology and Diagnostic Radiology (Mönchengladbach/ Leipzig), he started his residency in Diagnostic Radiology at the University Hospital Aachen. He was board certified for Diagnostic Radiology in December 1998, and became a fellow/staff member at this department thereafter. He received his PhD in Radiology in 2002, was appointed as vice-chairman of the department in 2006 and received a professorship at the RWTH Aachen in 2007. In July 2007 he became Head of Department, Diagnostic Radiology, HELIOS Klinikum Berlin-Buch, Charité Berlin, Campus Buch, Germany, before moving to his present position.

His per personal research topics are technical developments and functional imaging in computed tomography, contrast media research, cardiac imaging as well as image-guided interventions.

As PI for Imaging within CARIM he focusses on translational research, integrating different imaging modalities into the cardiovascular diagnostic chain, and favours multidisciplinary approaches to improve patient care.

Joachim-wildberger

Department of Radiology and Nuclear Medicine
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: 4.G2.013
T: +31(0)43 387 49 12

  • 2013
    • Landry, G., Parodi, K., Wildberger, J. E., & Verhaegen, F. (2013). Deriving concentrations of oxygen and carbon in human tissues using single- and dual-energy CT for ion therapy applications. Physics in Medicine and Biology, 58(15), 5029. https://doi.org/10.1088/0031-9155/58/15/5029
    • Versteylen, M. O., Joosen, I. A., Winkens, M. H., Laufer, E. M., Snijder, R. J., Wildberger, J. E., Crijns, H. J., Narula, J., & Hofstra, L. (2013). Combined use of exercise electrocardiography, coronary calcium score and cardiac CT angiography for the prediction of major cardiovascular events in patients presenting with stable chest pain. International Journal of Cardiology, 167(1), 121-125. https://doi.org/10.1016/j.ijcard.2011.12.016
    • Versteylen, M. O., Kietselaer, B. L., Dagnelie, P. C., Joosen, I. A., Dedic, A., Raaijmakers, R. H., Wildberger, J. E., Nieman, K., Crijns, H. J., Niessen, W. J., Daemen, M. J., & Hofstra, L. (2013). Additive Value of Semiautomated Quantification of Coronary Artery Disease Using Cardiac Computed Tomographic Angiography to Predict Future Acute Coronary Syndrome. Journal of the American College of Cardiology, 61(22), 2296-2305. https://doi.org/10.1016/j.jacc.2013.02.065
    • Kwee, R. M., van Oostenbrugge, R. J., Mess, W. H., Prins, M. H., van der Geest, R. J., Ter Berg, J. W., Franke, CL., Korten, A. G., Meems, B. J., van Engelshoven, J. M., Wildberger, J. E., & Kooi, M. E. (2013). MRI of carotid atherosclerosis to identify TIA and stroke patients who are at risk of a recurrence. Journal of Magnetic Resonance Imaging, 37(5), 1189-1194. https://doi.org/10.1002/jmri.23918
    • Schipper, R. J., Smidt, M. L., van Roozendaal, L. M., Castro, C. J., de Vries, B., Heuts, E. M., Keymeulen, K. B., Wildberger, J. E., Lobbes, M. B., & Beets-Tan, R. G. H. (2013). Noninvasive nodal staging in patients with breast cancer using gadofosveset-enhanced magnetic resonance imaging: a feasibility study. Investigative Radiology, 48(3), 134-139. https://doi.org/10.1097/RLI.0b013e318277f056
    • Jaarsma, C., Schalla, S., Cheriex, E. C., Smulders, M. W., van Dongen, I., Nelemans, P. J., Gorgels, A. P. M., Wildberger, J. E., Crijns, H. J. G. M., & Bekkers, B. (2013). Incremental value of cardiovascular magnetic resonance over echocardiography in the detection of acute and chronic myocardial infarction. Journal of Cardiovascular Magnetic Resonance, 15(1), Article 5. https://doi.org/10.1186/1532-429X-15-5
    • Truijman, M. T., Kwee, R. M., van Hoof, R. H., Hermeling, E., van Oostenbrugge, R. J., Mess, W. H., Backes, W. H., Daemen, M. J., Bucerius, J., Wildberger, J. E., & Kooi, M. E. (2013). Combined 18F-FDG PET-CT and DCE-MRI to Assess Inflammation and Microvascularization in Atherosclerotic Plaques.Stroke, 44(12), 3568-3570. https://doi.org/10.1161/STROKEAHA.113.003140
    • Gaens, M. E., Backes, W. H., Rozel, S., Lipperts, M., Sanders, S. N., Jaspers, K., Cleutjens, J. P. M., Sluimer, J. C., Heeneman, S., Daemen, M. J. A. P., Welten, R. J., Daemen, J. W., Wildberger, J. E., Kwee, R. M., & Kooi, M. E. (2013). Dynamic Contrast-enhanced MR Imaging of Carotid Atherosclerotic Plaque: Model Selection, Reproducibility, and Validation.Radiology, 266(1), 271-279. https://doi.org/10.1148/radiol.12120499
    • van de Weijer, T., Havekes, B., Bilet, L., Hoeks, J., Sparks, L., Bosma, M., Paglialunga, S., Jorgensen, J., Janssen, M. C., Schaart, G., Sauerwein, H. P., Smeets, J. L., Wildberger, J. E., Zechner, R., Schrauwen-Hinderling, V. B., Hesselink, M. K. C., & Schrauwen, P. (2013). Effects of Bezafibrate Treatment in a Patient and a Carrier With Mutations in the PNPLA2 Gene, Causing Neutral Lipid Storage Disease With Myopathy. Circulation Research, 112(5), e51-54. https://doi.org/10.1161/CIRCRESAHA.113.300944
    • Lobbes, M., Smidt, M. L., Keymeulen, K., Girometti, R., Zuiani, C., Beets Tan, R. G., Wildberger, J., & Boetes, C. (2013). Malignant lesions on mammography: accuracy of two different computer-aided detection systems. Clinical Imaging, 37(2), 283-288. https://doi.org/10.1016/j.clinimag.2012.04.017
    • Smulders, M. W., Kietselaer, B. L. J. H., Das, M., Wildberger, J. E., Crijns, H. J. G. M., Veenstra, L., Brunner La Rocca, H. P., van Dieijen-Visser, M. P., Mingels, A. M. A., Dagnelie, P. C., Post, M. J., Gorgels, A. P. M., van Asselt, A. D. I., Vogel, G., Schalla, S., Kim, R. J., & Bekkers, S. C. A. M. (2013). The role of cardiovascular magnetic resonance imaging and computed tomography angiography in suspected non-ST-elevation myocardial infarction patients: Design and rationale of the CARdiovascular Magnetic rEsoNance imaging and computed Tomography Angiography (CARMENTA) trial. American Heart Journal, 166(6), 968-975. https://doi.org/10.1016/j.ahj.2013.09.012
    • Lobbes, M. B., Prevos, R., Smidt, M. L., Tjan-Heijnen, V. C., van Goethem, M., Schipper, R., Beets-Tan, R. G., & Wildberger, J. E. (2013). The role of magnetic resonance imaging in assessing residual disease and pathologic complete response in breast cancer patients receiving neoadjuvant chemotherapy: a systematic review. Insights into Imaging, January(20113). https://doi.org/10.1007/s13244-013-0219-y
  • 2012
    • Weijs, B., Pisters, R., Haest, R. J., Kragten, J. A., Joosen, I. A., Versteylen, M., Timmermans, C. C., Pison, L., Blaauw, Y., Hofstra, L., Nieuwlaat, R., Wildberger, J., & Crijns, H. J. (2012). Patients originally diagnosed with idiopathic atrial fibrillation more often suffer from insidious coronary artery disease compared to healthy sinus rhythm controls. Heart Rhythm, 9(12), 1923-1929. https://doi.org/10.1016/j.hrthm.2012.08.013
    • Postma, A. A., Hofman, P. A. M., Stadler, A. A. R., van Oostenbrugge, R. J., Tijssen, M. P. M., & Wildberger, J. E. (2012). Dual-Energy CT of the Brain and Intracranial Vessels. American Journal of Roentgenology, 199(5), S26-S33. https://doi.org/10.2214/AJR.12.9115
    • Kwee, R. M., Truijman, M. T., van Oostenbrugge, R. J., Mess, W. H., Prins, M. H., Franke, CL., Korten, A. G., Wildberger, J. E., & Kooi, M. E. (2012). Longitudinal MRI study on the natural history of carotid artery plaques in symptomatic patients. PLOS ONE, 7(7), Article 42472. https://doi.org/10.1371/journal.pone.0042472
    • Versluis, B., Dremmen, M. H. G., Nelemans, P. J., Wildberger, J. E., Schurink, G.-W., Leiner, T., & Backes, W. H. (2012). Dynamic Contrast-Enhanced MRI Assessment of Hyperemic Fractional Microvascular Blood Plasma Volume in Peripheral Arterial Disease: Initial Findings. PLOS ONE, 7(5), Article e37756. https://doi.org/10.1371/journal.pone.0037756
    • Jaarsma, C., Leiner, T., Bekkers, S. C., Crijns, H. J., Wildberger, J. E., Nagel, E., Nelemans, P. J., & Schalla, S. (2012). Diagnostic Performance of Noninvasive Myocardial Perfusion Imaging Using Single-Photon Emission Computed Tomography, Cardiac Magnetic Resonance, and Positron Emission Tomography Imaging for the Detection of Obstructive Coronary Artery Disease A Meta-Analysis. Journal of the American College of Cardiology, 59(19), 1719-1728. https://doi.org/10.1016/j.jacc.2011.12.040
    • Takx, R. A. P., Moscariello, A., Schoepf, U. J., Barraza, J. M. J., Nance, J. W. . J., Bastarrika, G., Das, M., Meyer, M., Wildberger, J. E., Schoenberg, S. O., Fink, C., & Henzler, T. (2012). Quantification of left and right ventricular function and myocardial mass: Comparison of low-radiation dose 2nd generation dual-source CT and cardiac MRI. European Journal of Radiology, 81(4), E598-E604. https://doi.org/10.1016/j.ejrad.2011.07.001
    • Versluis, B., Dremmen, M. H. G., Nelemans, P. J., Wildberger, J. E., Schurink, G.-W., Leiner, T., & Backes, W. H. (2012). MRI of Arterial Flow Reserve in Patients with Intermittent Claudication: Feasibility and Initial Experience. PLOS ONE, 7(3), Article e31514. https://doi.org/10.1371/journal.pone.0031514
    • van de Weijer, T., van Ewijk, P. A., Zandbergen, H. R., Slenter, J. M., Kessels, A. G., Wildberger, J. E., Hesselink, M. K. C., Schrauwen, P., Schrauwen-Hinderling, V. B., & Kooi, M. E. (2012). Geometrical models for cardiac MRI in rodents: comparison of quantification of left ventricular volumes and function by various geometrical models with a full-volume MRI data set in rodents.American Journal of Physiology-heart and Circulatory Physiology, 302(3), H709-H715. https://doi.org/10.1152/ajpheart.00710.2011
    • Mingels, A. M., Joosen, I. A., Versteylen, M. O., Laufer, E. M., Winkens, M. H., Wildberger, J. E., van Dieijen-Visser, M. P., & Hofstra, L. (2012). High-sensitivity cardiac troponin t: Risk stratification tool in patients with symptoms of chest discomfort. PLOS ONE, 7(4), Article e35059. https://doi.org/10.1371/journal.pone.0035059
    • Prevos, R., Smidt, M. L., Tjan-Heijnen, V. C., van Goethem, M., Beets Tan, R. G., Wildberger, J. E., & Lobbes, M. B. (2012). Pre-treatment differences and early response monitoring of neoadjuvant chemotherapy in breast cancer patients using magnetic resonance imaging: a systematic review. European Radiology, 22(12), 2607-2616. https://doi.org/10.1007/s00330-012-2653-5
    • Joosen, I. A., Schiphof, F., Versteylen, M. O., Laufer, E. M., Winkens, M. H., Nelemans, P. J., Kooman, J. P., Hofstra, L., Wildberger, J. E., & Leiner, T. (2012). Relation between Mild to Moderate Chronic Kidney Disease and Coronary Artery Disease Determined with Coronary CT Angiography. PLOS ONE, 7(10), Article e47267. https://doi.org/10.1371/journal.pone.0047267
    • Maas, M., Lambregts, D. M., Lahaye, M. J., Beets, G. L., Backes, W. H., Vliegen, R. F., Osinga-de Jong, M., Wildberger, J. E., & Beets Tan, R. G. (2012). T-staging of rectal cancer: accuracy of 3.0 Tesla MRI compared with 1.5 Tesla.Abdominal Imaging, 37(3), 475-481. https://doi.org/10.1007/s00261-011-9770-5
  • 2011
    • Landry, G., Granton, P. V., Reniers, B., Ollers, M. C., Beaulieu, L., Wildberger, J. E., & Verhaegen, F. (2011). Simulation study on potential accuracy gains from dual energy CT tissue segmentation for low-energy brachytherapy Monte Carlo dose calculations. Physics in Medicine and Biology, 56(19), 6257-6278. https://doi.org/10.1088/0031-9155/56/19/007
    • Weijs, B., Blaauw, Y., Rennenberg, R. J. M. W., Schurgers, L. J., Timmermans, C. C. M. M., Pison, L., Nieuwlaat, R., Hofstra, L., Kroon, A. A., Wildberger, J., & Crijns, H. J. G. M. (2011). Patients using vitamin K antagonists show increased levels of coronary calcification: an observational study in low-risk atrial fibrillation patients. European Heart Journal, 32(20), 2555-2562. https://doi.org/10.1093/eurheartj/ehr226
    • Landry, G., Reniers, B., Granton, P. V., van Rooijen, B. D., Beaulieu, L., Wildberger, J. E., & Verhaegen, F. (2011). Extracting atomic numbers and electron densities from a dual source dual energy CT scanner: Experiments and a simulation model. Radiotherapy and Oncology, 100(3), 375-379. https://doi.org/10.1016/j.radonc.2011.08.029
    • Kemerink, M., Dierichs, T. J., Dierichs, J., Huynen, H. J. M., Wildberger, J. E., van Engelshoven, J. M. A., & Kemerink, G. J. (2011). Characteristics of a First-Generation X-Ray System. Radiology, 259(2), 534-539. https://doi.org/10.1148/radiol.11101899
    • Kwee, R. M., Truijman, M. T. B., Mess, W. H., Teule, G. J. J., Ter Berg, J. W., Franke, CL., Korten, A. G., Meems, B. J., Prins, M. H., van Engelshoven, J. M. A., Wildberger, J. E., van Oostenbrugge, R. J., & Kooi, M. E. (2011). Potential of integrated (18F) fluordeoxyglucose positron-emission tomography/CT in identifying vulnerable carotid plaques. American Journal of Neuroradiology, 32(5), 950-954. https://doi.org/10.3174/ajnr.A2381
    • Mahnken, A. H., Klotz, E., Schreiber, S., Bruners, P., Isfort, P., Guenther, R. W., & Wildberger, J. E. (2011). Volumetric Arterial Enhancement Fraction Predicts Tumor Recurrence After Hepatic Radiofrequency Ablation of Liver Metastases: Initial Results. American Journal of Roentgenology, 196(5), W573-W579. https://doi.org/10.2214/AJR.10.4410
    • Lambregts, D. M., Beets, G. L., Maas, M., Kessels, A. G. H., Bakers, F. C., Cappendijk, V. C., Engelen, S. M., Lahaye, M. J., de Bruine, A. P., Lammering, G., Leiner, T., Verwoerd, J. L., Wildberger, J. E., & Beets Tan, R. G. (2011). Accuracy of Gadofosveset-enhanced MRI for Nodal Staging and Restaging in Rectal Cancer. Annals of Surgery, 253(3), 539-545. https://doi.org/10.1097/SLA.0b013e31820b01f1
    • Bilet, L., van de Weijer, T., Hesselink, M. K. C., Glatz, J. F., Lamb, H. J., Wildberger, J. E., Kooi, M. E., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2011). Exercise-induced modulation of cardiac lipid content in healthy lean young men. Basic Research in Cardiology, 106(2), 307-315. https://doi.org/10.1007/s00395-010-0144-x
    • Kwee, R. M., Hofman, P. A., Gronenschild, E. H., van Oostenbrugge, R. J., Mess, W. H., Ter Berg, J. W., Franke, CL., Korten, A. G., Meems, B. J., van Engelshoven, J. M., Wildberger, J. E., & Kooi, M. E. (2011). Association between carotid plaque characteristics and cerebral white matter lesions: one-year follow-up study by MRI. PLOS ONE, 6(2), Article e17070. https://doi.org/10.1371/journal.pone.0017070
    • Schrauwen-Hinderling, V. B., Meex, R. C., Hesselink, M. K. C., van de Weijer, T., Leiner, T., Schar, M., Lamb, H. J., Wildberger, J. E., Glatz, J. F., Schrauwen, P., & Kooi, M. E. (2011). Cardiac lipid content is unresponsive to a physical activity training intervention in type 2 diabetic patients, despite improved ejection fraction. Cardiovascular Diabetology, 10(1), 47. https://doi.org/10.1186/1475-2840-10-47
    • Versluis, B., Backes, W. H., van Eupen, M. G. A., Jaspers, K., Nelemans, P. J., Rouwet, E. V., Teijink, J. A. W., Mali, W. P. T. M., Schurink, G. W. H., Wildberger, J. E., & Leiner, T. (2011). Magnetic Resonance Imaging in Peripheral Arterial Disease Reproducibility of the Assessment of Morphological and Functional Vascular Status. Investigative Radiology, 46(1), 11-24. https://doi.org/10.1097/RLI.0b013e3181f2bfb8
    • Bekkers, S. C., Lemmert, M. E., Passos, V. L., Mihl, C., Schalla, S., Wildberger, J. E., Waltenberger, J., & Gorgels, A. P. M. (2011). The relationships between cardiovascular magnetic resonance imaging variables of acute myocardial infarction and both left ventricular dysfunction and immediate postreperfusion ST segment recovery. Journal of Electrocardiology, 44(5), 561-567. https://doi.org/10.1016/j.jelectrocard.2011.07.006
  • 2010
    • Kwee, R. M., van Oostenbrugge, R. J., Prins, M. H., Ter Berg, J. W., Franke, CL., Korten, A. G., Meems, B. J., van Engelshoven, J. M., Wildberger, J. E., Mess, W. H., & Kooi, M. E. (2010). Symptomatic Patients With Mild and Moderate Carotid Stenosis. Plaque Features at MRI and Association With Cardiovascular Risk Factors and Statin Use. Stroke, 41(7), 1389-1393. https://doi.org/10.1161/STROKEAHA.109.575670
    • Laufer, E. M., Mingels, A. M. A., Winkens, M. H. M., Joosen, I. A. P. G., Schellings, M. W. M., Leiner, T., Wildberger, J. E., Narula, J., Van Dieijen-Visser, M. P., & Hofstra, L. (2010). The Extent of Coronary Atherosclerosis Is Associated With Increasing Circulating Levels of High Sensitive Cardiac Troponin T. Arteriosclerosis Thrombosis and Vascular Biology, 30(6), 1269-1275. https://doi.org/10.1161/ATVBAHA.109.200394
    • Schrauwen-Hinderling, V. B., Hesselink, M. K. C., Meex, R. C. R., van der Made, S., Schar, M., Lamb, H., Wildberger, J. E., Glatz, J. F., Snoep, G., Kooi, M. E., & Schrauwen, P. (2010). Improved ejection fraction after exercise training in obesity is accompanied by reduced cardiac lipid content.Journal of Clinical Endocrinology & Metabolism, 95(4), 1932-1938. https://doi.org/10.1210/jc.2009-2076
    • Schalla, S., Bekkers, S. C., Dennert, R., van Suylen, R. J., Waltenberger, J., Leiner, T., Wildberger, J., Crijns, H. J., & Heymans, S. (2010). Replacement and reactive myocardial fibrosis in idiopathic dilated cardiomyopathy: comparison of magnetic resonance imaging with right ventricular biopsy. European journal of heart failure, 12(3), 227-231. https://doi.org/10.1093/eurjhf/hfq004
    • Mühlenbruch, G., Das, M., Mommertz, G., Schaaf, M., Langer, S., Mahnken, A. H., Wildberger, J. E., Thron, A., Guenther, R. W., & Krings, T. (2010). Comparison of dual-source CT angiography and MR angiography in preoperative evaluation of intra- and extracranial vessels: a pilot study. European Radiology, 20(2), 469-476. https://doi.org/10.1007/s00330-009-1547-7
    • Kwee, R. M., van Oostenbrugge, R. J., Mess, W. H., Prins, M. H., van der Geest, R. J., Ter Berg, J. W., Franke, CL., Korten, A. G., Meems, B. J., van Engelshoven, J. M., Wildberger, J. E., & Kooi, M. E. (2010). Carotid plaques in transient ischemic attack and stroke patients: one-year follow-up study by magnetic resonance imaging.Investigative Radiology, 45(12), 803-809. https://doi.org/10.1097/RLI.0b013e3181ed15ff
    • Yamamura, J., Tornquist, K., Buchert, R., Wildberger, J., Nagel, H. D., Dichtl, D., Adam, G., & Wedegaertner, U. (2010). Simulated Low-Dose Computed Tomography in Oncological Patients: A Feasibility Study. Journal of Computer Assisted Tomography, 34(2), 302-308. https://doi.org/10.1097/RCT.0b013e3181c95b67
  • 2009
    • Kwee, R. M., Schreuder, F. H., Mess, W. H., van Oostenbrugge, R. J., Triebels, V. H., van de Akker, L. H., Heeneman, S., Hofman, P. A. M., van Engelshoven, J. M., Wildberger, J. E., & Kooi, M. E. (2009). Images in cardiovascular medicine: development of carotid intraplaque hemorrhage demonstrated by serial magnetic resonance imaging. Circulation, 120(16), 1637-9. https://doi.org/10.1161/CIRCULATIONAHA.109.873513
    • Kwee, R. M., Teule, G. J. J., van Oostenbrugge, R. J., Mess, W. H., Prins, M. H., van der Geest, R. J., Ter Berg, J. W., Franke, CL., Korten, A. G., Meems, B. J., Hofman, P. A. M., van Engelshoven, J. M., Wildberger, J. E., & Kooi, M. E. (2009). Multimodality imaging of carotid artery plaques: 18F-fluoro-2-deoxyglucose positron emission tomography, computed tomography, and magnetic resonance imaging. Stroke, 40(12), 3718-24. https://doi.org/10.1161/STROKEAHA.109.564088
    • Kwee, R. M., van Engelshoven, J. M. A., Mess, W. H., ter Berg, J. W. M., Schreuder, F. H. B. M., Franke, CL., Korten, A., Meems, B. J., van Oostenbrugge, R. J., Wildberger, J. E., & Kooi, M. E. (2009). Reproducibility of Fibrous Cap Status Assessment of Carotid Artery Plaques by Contrast-Enhanced MRI. Stroke, 40(9), 3017-3021. https://doi.org/10.1161/STROKEAHA.109.555052
Overview