Robert van Oostenbrugge

Professor

Robert van Oostenbrugge is Professor of Neurology, with a chair on Vascular Neurology, head of the Department of Neurology (UM); principal Investigator of CARIM and programme leader of Vascular Neurology / Stroke. Robert (R.J.) van Oostenbrugge; (born Havelte, 1965) obtained a MD at the Maastricht University in Maastricht (1990). He was registered as neurologist in 2000 and obtained a PhD in 1999 (University Maastricht, Maastricht). In 2013, he was appointed Professor of Neurology chair of the Department of Neurology at Maastricht University. He is member of the Centers of Excellence in Neurodegeneration initiative and of the JPND funded initiative HARNESS aiming to harmonise imaging standards in vascular dementia, member of the board of the Dutch Section of Vascular Neurology.

Department of Neurology
P. Debyelaan 25, 6229 HX Maastricht
PO Box 5800, 6202 AZ Maastricht
T: +31 (0)43 387 70 58

2017
- Claessens, D., Bekelaar, K., Schreuder, F. H. B. M., de Greef, B. T. A., Vlooswijk, M. C. G., Staals, J., van Oostenbrugge, R. J., & Rouhl, R. P. W. (2017). Mortality after primary intracerebral hemorrhage in relation to post-stroke seizures. Journal of Neurology, 264(9), 1885-1891. https://doi.org/10.1007/s00415-017-8573-1
- Borst, J., Berkhemer, O. A., Santos, E. M. M., Yoo, A. J., den Blanken, M., Roos, Y. B. W. E. M., van Bavel, E., van Zwam, W. H., van Oostenbrugge, R. J., Lingsma, H. F., van der Lugt, A., Dippel, D. W. J., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Investigators (2017). Value of Thrombus CT Characteristics in Patients with Acute Ischemic Stroke. American Journal of Neuroradiology, 38(9), 1758-1764. https://doi.org/10.3174/ajnr.A5331
- Venema, E., Boodt, N., Berkhemer, O. A., Rood, P. P. M., van Zwam, W. H., van Oostenbrugge, R. J., van der Lugt, A., Roos, Y. B. W. E. M., Majoie, C. B. L. M., Lingsma, H. F., Dippel, D. W. J., & MR CLEAN Investigators (2017). Workflow and factors associated with delay in the delivery of intra-arterial treatment for acute ischemic stroke in the MR CLEAN trial. Journal of Neurointerventional Surgery, 10(5), 424-U19. https://doi.org/10.1136/neurintsurg-2017-013198
- Mulder, M. J. H. L., Ergezen, S., Lingsma, H. F., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., van den Berg, L. A., Nijeholt, G. L. A., Emmer, B. J., van der Worp, H. B., Nederkoorn, P. J., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., & Multicenter Randomized Clinical Tr (2017). Baseline Blood Pressure Effect on the Benefit and Safety of Intra-Arterial Treatment in MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment of Acute Ischemic Stroke in the Netherlands). Stroke, 48(7), 1869-1876. https://doi.org/10.1161/STROKEAHA.116.016225
- Wong, S. M., Jansen, J. F. A., Zhang, C. E., Staals, J., Hofman, P. A. M., van Oostenbrugge, R. J., Jeukens, C. R. L. P. N., & Backes, W. H. (2017). Measuring subtle leakage of the blood-brain barrier in cerebrovascular disease with DCE-MRI: Test-retest reproducibility and its influencing factors. Journal of Magnetic Resonance Imaging, 46(1), 159-166. https://doi.org/10.1002/jmri.25540
- Berkhemer, O. A., Borst, J., Kappelhof, M., Yoo, A. J., van den Berg, L. A., Fransen, P. S. S., Beumer, D., Schonewille, W. J., Nederkoorn, P. J., Wermer, M. J. H., Marquering, H. A., Lingsma, H. F., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Dippel, D. W. J., van Zwam, W. H., Majoie, C. B. L. M., Emmer, B. J., van der Lugt, A., & MR CLEAN Investigators (2017). Extracranial Carotid Disease and Effect of Intra-arterial Treatment in Patients With Proximal Anterior Circulation Stroke in MR CLEAN. Annals of Internal Medicine, 166(12), 867-875. https://doi.org/10.7326/M16-1536
- Beumer, D., van Boxtel, T. H., Schipperen, S., van Zwam, W. H., Nijeholt, G. J. L. A., Brouwer, P. A., Jenniskens, S. F. M., Schonewille, W. J., Vos, J. A., van der Lugt, A., Roos, Y. B., Majoie, C. B., van Oostenbrugge, R. J., Dippel, D. W. J., & MR CLEAN Pretrial Investigators (2017). The relationship between interventionists' experience and clinical and radiological outcome in intra-arterial treatment for acute ischemic stroke. A MR CLEAN pretrial survey. Journal of the Neurological Sciences, 377, 97-101. https://doi.org/10.1016/j.jns.2017.04.002
- Mulder, M. J. H. L., Berkhemer, O. A., Fransen, P. S. S., van den Berg, L. A., Lingsma, H. F., den Hertog, H. M., Staals, J., Jenniskens, S. F. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., & MR CLEAN Investigators (2017). Does prior antiplatelet treatment improve functional outcome after intra-arterial treatment for acute ischemic stroke?International journal of stroke, 12(4), 368-376. https://doi.org/10.1177/1747493016677842
- Uiterwijk, R., Staals, J., Huijts, M., de Leeuw, P. W., Kroon, A. A., & van Oostenbrugge, R. J. (2017). MRI progression of cerebral small vessel disease and cognitive decline in patients with hypertension. Journal of Hypertension, 35(6), 1263-1270. https://doi.org/10.1097/HJH.0000000000001294
- Venema, E., Mulder, M. J. H. L., Roozenbeek, B., Broderick, J. P., Yeatts, S. D., Khatri, P., Berkhemer, O. A., Emmer, B. J., Roos, Y. B. W. E. M., Majoie, C. B. L. M., van Oostenbrugge, R. J., van Zwam, W. H., van der Lugt, A., Steyerberg, E. W., Dippel, D. W. J., & Lingsma, H. F. (2017). Selection of patients for intra-arterial treatment for acute ischaemic stroke: development and validation of a clinical decision tool in two randomised trials. BMJ, 357, Article j1710. https://doi.org/10.1136/bmj.j1710
- Osei, E., den Hertog, H. M., Berkhemer, O. A., Fransen, P. S. S., Roos, Y. B. W. E. M., Beumer, D., van Oostenbrugge, R. J., Schonewille, W. J., Boiten, J., Zandbergen, A. A. M., Koudstaal, P. J., MR CLEAN Investigators, van Zwam, W., & Dippel, D. W. J. (2017). Admission Glucose and Effect of Intra-Arterial Treatment in Patients With Acute Ischemic Stroke. Stroke, 48(5), 1299-1305. https://doi.org/10.1161/STROKEAHA.116.016071
- Hauer, A. J., Ruigrok, Y. M., Algra, A., van Dijk, E. J., Koudstaal, P. J., Luijckx, G.-J., Nederkoorn, P. J., van Oostenbrugge, R. J., Visser, M. C., Wermer, M. J., Kappelle, L. J., Klijn, C. J. M., & Dutch Parelsnoer Inst-Cerebrovasc (2017). Age-Specific Vascular Risk Factor Profiles According to Stroke Subtype. Journal of the American Heart Association, 6(5), Article 005090. https://doi.org/10.1161/JAHA.116.005090
- Bucker, A., Boers, A. M., Bot, J. C. J., Berkhemer, O. A., Lingsma, H. F., Yoo, A. J., Van Zwam, W. H., Van Oostenbrugge, R. J., Van der Lugt, A., Dippel, D. W. J., Roos, Y. B. W. E. M., Majoie, C. B. L. M., Marquering, H. A., MR CLEAN Trial Investigators, & Multictr Randomized Clinical Trial (2017). Associations of Ischemic Lesion Volume With Functional Outcome in Patients With Acute Ischemic Stroke 24-Hour Versus 1-Week Imaging. Stroke, 48(5), 1233-1240. https://doi.org/10.1161/STROKEAHA.116.015156
- Boers, A. M. M., Berkhemer, O. A., Slump, C. H., van Zwam, W. H., Roos, Y. B. W. E. M., van der Lugt, A., van Oostenbrugge, R. J., Yoo, A. J., Dippel, D. W. J., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Trial Investigators (2017). Topographic distribution of cerebral infarct probability in patients with acute ischemic stroke: mapping of intra-arterial treatment effect. Journal of Neurointerventional Surgery, 9(5), 431-436. https://doi.org/10.1136/neurintsurg-2016-012387
- van den Berg, L. A., Dijkgraaf, M. G. W., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., Lingsma, H. F., Majoie, C. B. L. M., Dippel, D. W. J., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Roos, Y. B. W. E. M., & MR CLEAN Investigators (2017). Two-Year Outcome after Endovascular Treatment for Acute Ischemic Stroke. New England Journal of Medicine, 376(14), 1341-1349. https://doi.org/10.1056/NEJMoa1612136
- van Bussel, F. C. G., Backes, W. H., Hofman, P. A. M., van Oostenbrugge, R. J., van Boxtel, M. P. J., Verhey, F. R. J., Steinbusch, H. W. M., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. JFA. (2017). Cerebral pathology and cognition in diabetes: the merits of multiparametric neuroimaging. Frontiers in Neuroscience, 11(APR), Article 188. https://doi.org/10.3389/fnins.2017.00188
- Zhang, C. E., Wong, S. M., Uiterwijk, R., Staals, J., Backes, W. H., Hoff, E. I., Schreuder, T., Jeukens, C. R. L. P. N., Jansen, J. F. A., & van Oostenbrugge, R. J. (2017). Intravoxel Incoherent Motion Imaging in Small Vessel Disease Microstructural Integrity and Microvascular Perfusion Related to Cognition. Stroke, 48(3), 658-663. https://doi.org/10.1161/STROKEAHA.116.015084
- Mulder, M. J. H. L., Venema, E., Roozenbeek, B., Broderick, J. P., Yeatts, S. D., Khatri, P., Berkhemer, O. A., Roos, Y. B. W. E. M., Majoie, C. B. L. M., van Oostenbrugge, R. J., van Zwam, W. H., van der Lugt, A., Steyerberg, E. W., Dippel, D. W. J., & Lingsma, H. F. (2017). Towards personalised intra- arterial treatment of patients with acute ischaemic stroke: a study protocol for development and validation of a clinical decision aid. BMJ Open, 7(3), Article 013699. https://doi.org/10.1136/bmjopen-2016-013699
- Wagemans, B. A. J. M., van Zwam, W. H., Nelemans, P. J., van Oostenbrugge, R. J., & Postma, A. A. (2017). 4D-CTA improves diagnostic certainty and accuracy in the detection of proximal intracranial anterior circulation occlusion in acute ischemic stroke. PLOS ONE, 12(2), Article 0172356. https://doi.org/10.1371/journal.pone.0172356
- Zhang, C. E., Wong, S. M., van de Haar, H. J., Staals, J., Jansen, J. F. A., Jeukens, C. R. L. P. N., Hofman, P. A. M., van Oostenbrugge, R. J., & Backes, W. H. (2017). Blood-brain barrier leakage is more widespread in patients with cerebral small vessel disease. Neurology, 88(5), 426-432. https://doi.org/10.1212/WNL.0000000000003556
- van Hoof, R. H. M., Schreuder, F. H. B. M., Nelemans, P., Truijman, M. T. B., van Orshoven, N. P., Schreuder, T. H., Mess, W. H., Heeneman, S., van Oostenbrugge, R. J., Wildberger, J. E., & Kooi, M. E. (2017). Ischemic Stroke Patients Demonstrate Increased Carotid Plaque Microvasculature Compared to (Ocular) Transient Ischemic Attack Patients. Cerebrovascular Diseases, 44(5-6), 297-303. https://doi.org/10.1159/000481146
- Wong, S. M., Zhang, C. E., van Bussel, F. C. G., Staals, J., Jeukens, C. R. L. P. N., Hofman, P. A. M., van Oostenbrugge, R. J., Backes, W. H., & Jansen, J. F. A. (2017). Simultaneous investigation of microvasculature and parenchyma in cerebral small vessel disease using intravoxel incoherent motion imaging. NeuroImage: Clinical, 14, 216-221. https://doi.org/10.1016/j.nicl.2017.01.017
- Douven, E., Kohler, S., Schievink, S. H. J., van Oostenbrugge, R. J., Staals, J., Verhey, F. RJ., & Aalten, P. (2017). Temporal Associations between Fatigue, Depression, and Apathy after Stroke: Results of the Cognition and Affect after Stroke, a Prospective Evaluation of Risks Study. Cerebrovascular Diseases, 44(5-6), 330-337. https://doi.org/10.1159/000481577
- Hooghiemstra, A. M., Bertens, A. S., Leeuwis, A. E., Bron, E. E., Bots, M. L., Brunner-La Rocca, H.-P., de Craen, A. J. M., van der Geest, R. J., Greving, J. P., Kappelle, L. J., Niessen, W. J., van Oostenbrugge, R. J., van Osch, M. J. P., de Roos, A., van Rossum, A. C., Biessels, G. J., van Buchem, M. A., Daemen, M. J. A. P., van der Flier, W. M., & Heart-Brain Connection Consortium (2017). The Missing Link in the Pathophysiology of Vascular Cognitive Impairment: Design of the Heart-Brain Study. Cerebrovascular Diseases Extra, 7(3), 140-152. https://doi.org/10.1159/000480738
2016
- Osei, E., Hertog, H. M. D., Berkhemer, O. A., Fransen, P. S. S., Roos, Y. B. W. E. M., Beumer, D., van Oostenbrugge, R. J., Schonewille, W. J., Boiten, J., Zandbergen, A. A. M., Koudstaal, P. J., & Dippel, D. W. J. (2016). Increased admission and fasting glucose are associated with unfavorable short-term outcome after intra-arterial treatment of ischemic stroke in the MR CLEAN pretrial cohort. Journal of the Neurological Sciences, 371, 1-5. https://doi.org/10.1016/j.jns.2016.10.003
- Uiterwijk, R., van Oostenbrugge, R. J., Huijts, M., De Leeuw, P. W., Kroon, A. A., & Staals, J. (2016). Total Cerebral Small Vessel Disease MRI Score Is Associated with Cognitive Decline in Executive Function in Patients with Hypertension. Frontiers in Aging Neuroscience, 8(DEC), Article 301. https://doi.org/10.3389/fnagi.2016.00301
- Jansen, J., van Bussel, F. C. G., van de Haar, H. J., van Osch, M. J. P., Hofman, P. A. M., van Boxtel, M. P. J., van Oostenbrugge, R. J., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Backes, W. H. (2016). Cerebral blood flow, blood supply, and cognition in Type 2 Diabetes Mellitus. Scientific Reports, 6(1), Article 10. https://doi.org/10.1038/s41598-016-0003-6
- Treurniet, K. M., Yoo, A. J., Berkhemer, O. A., Lingsma, H. F., Boers, A. M. M., Fransen, P. S. S., Beumer, D., van den Berg, L. A., Sprengers, M. E. S., Jenniskens, S. F. M., Nijeholt, G. J. L. A., van Walderveen, M. A. A., Bot, J. C. J., Beenen, L. F. M., van den Berg, R., van Zwam, W. H., van der Lugt, A., van Oostenbrugge, R. J., Dippel, D. W. J., ... Majoie, C. B. L. M. (2016). Clot Burden Score on Baseline Computerized Tomographic Angiography and Intra-Arterial Treatment Effect in Acute Ischemic Stroke. Stroke, 47(12), 2972-2978. https://doi.org/10.1161/STROKEAHA.116.014565
- Dichgans, M., Wardlaw, J., Smith, E., Zietemann, V., Seshadri, S., Sachdev, P., Biessels, G. J., Fazekas, F., Benavente, O., Pantoni, L., De Leeuw, F., Norrving, B., Matthews, P., Chen, C., Mok, V., Duering, M., Whiteley, W., Shuler, K., Alonso, A., ... Yang, Y.-H. (2016). METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: An initiative of the Joint Programme for Neurodegenerative Disease Research. Alzheimer's & Dementia, 12(12), 1235-1249. https://doi.org/10.1016/j.jalz.2016.06.004
- van den Berg, L. A., Dijkgraaf, M. G. W., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., Lingsma, H., Majoie, C. B. M., Dippel, D. W. J., van der Lugt, A. J., van Oostenbrugge, R. J., van Zwam, W. H., & Roos, Y. B. W. E. M. (2016). Two-year clinical follow-up of the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in The Netherlands (MR CLEAN): design and statistical analysis plan of the extended follow-up study. Trials, 17(1), Article 555. https://doi.org/10.1186/s13063-016-1669-6
- Jansen, I. G. H., Berkhemer, O. A., Yoo, A. J., Vos, J. A., Lycklama, G. J., Sprengers, M. E. S., van Zwam, W. H., Schonewille, W. J., Boiten, J., van Walderveen, M. A. A., van Oostenbrugge, R. J., van der Lugt, A., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Investigators (2016). Comparison of CTA- and DSA-Based Collateral Flow Assessment in Patients with Anterior Circulation Stroke. American Journal of Neuroradiology, 37(11), 2037-2042. https://doi.org/10.3174/ajnr.A4878
- Dippel, D. W., Majoie, C. B., Roos, Y. B., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Lingsma, H. F., Koudstaal, P. J., Treurniet, K. M., van den Berg, L. A., Beumer, D., Fransen, P. S., & Berkhemer, O. A. (2016). Influence of Device Choice on the Effect of Intra-Arterial Treatment for Acute Ischemic Stroke in MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands). Stroke, 47(10), 2574-2581. https://doi.org/10.1161/STROKEAHA.116.013929
- Saver, J. L., Goyal, M., van der Lugt, A., Menon, B. K., Majoie, C. B. L. M., Dippel, D. W., Campbell, B. C., Nogueira, R. G., Demchuk, A. M., Tomasello, A., Cardona, P., Devlin, T. G., Frei, D. F., de Rochemont, R. D. M., Berkhemer, O. A., Jovin, T. G., Siddiqui, A. H., van Zwam, W. H., Davis, S. M., ... Hill, M. D. (2016). Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis. JAMA-Journal of the American Medical Association, 316(12), 1279-1288. https://doi.org/10.1001/jama.2016.13647
- Al-Ali, F., Berkhemer, O. A., Yousman, W. P., Elias, J. J., Bender, E. N., Lingsma, H. F., van der Lugt, A., Dippel, D. W. J., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Dillon, W. P., & Majoie, C. B. L. M. (2016). The Capillary Index Score as a Marker of Viable Cerebral Tissue: Proof of Concept-The Capillary Index Score in the MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands) Trial. Stroke, 47(9), 2286-2291. https://doi.org/10.1161/STROKEAHA.116.013513
- Berkhemer, O. A., van den Berg, L. A., Fransen, P. S. S., Beumer, D., Yoo, A. J., Lingsma, H. F., Schonewille, W. J., van den Berg, R., Wermer, M. J. H., Boiten, J., Nijeholt, G. J. L., Nederkoorn, P. J., Hollmann, M. W., van Zwam, W. H., van der Lugt, A., van Oostenbrugge, R. J., Majoie, C. B. L. M., Dippel, D. W. J., & Roos, Y. B. W. E. M. (2016). The effect of anesthetic management during intra-arterial therapy for acute stroke in MR CLEAN. Neurology, 87(7), 656-664. https://doi.org/10.1212/WNL.0000000000002976
- van Overbeek, E. C., Staals, J., & van Oostenbrugge, R. J. (2016). Decreased kidney function relates to progression of cerebral microbleeds in lacunar stroke patients. International journal of stroke, 11(6), 695-700. https://doi.org/10.1177/1747493016641966
- De Guio, F., Jouvent, E., Biessels, G. J., Black, S. E., Brayne, C., Chen, C., Cordonnier, C., De Leeuw, F.-E., Dichgans, M., Doubal, F., Duering, M., Dufouil, C., Duzel, E., Fazekas, F., Hachinski, V., Ikram, M. A., Linn, J., Matthews, P. M., Mazoyer, B., ... Chabriat, H. (2016). Reproducibility and variability of quantitative magnetic resonance imaging markers in cerebral small vessel disease. Journal of Cerebral Blood Flow and Metabolism, 36(8), 1319-1337. https://doi.org/10.1177/0271678X16647396
- Mulder, M. J. H. L., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., van den Berg, L. A., Lingsma, H. F., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., & Dippel, D. W. J. (2016). Treatment in patients who are not eligible for intravenous alteplase: MR CLEAN subgroup analysis. International journal of stroke, 11(6), 637-645. https://doi.org/10.1177/1747493016641969
- Wilde, B., Mertens, A., Arends, S. J., Rouhl, R. P., Bijleveld, R., Huitema, J., Timmermans, S. A., Damoiseaux, J., Witzke, O., Duijvestijn, A. M., van Paassen, P., van Oostenbrugge, R. J., & Tervaert, J. W. C. (2016). Endothelial progenitor cells are differentially impaired in ANCA-associated vasculitis compared to healthy controls. Arthritis Research & Therapy, 18(1), Article 147. https://doi.org/10.1186/s13075-016-1044-8
- Yoo, A. J., Berkhemer, O. A., Fransen, P. S. S., van den Berg, L. A., Beumer, D., Lingsma, H. F., Schonewille, W. J., Sprengers, M. E. S., van den Berg, R., van Walderveen, M. A. A., Beenen, L. F. M., Wermer, M. J. H., Nijeholt, G. J. L. A., Boiten, J., Jenniskens, S. F. M., Bot, J. C. J., Boers, A. M. M., Marquering, H. A., Roos, Y. B. W. E. M., ... Majoie, C. B. L. M. (2016). Effect of baseline Alberta Stroke Program Early CT Score on safety and efficacy of intra-arterial treatment: a subgroup analysis of a randomised phase 3 trial (MR CLEAN). Lancet Neurology, 15(7), 685-694. https://doi.org/10.1016/S1474-4422(16)00124-1
- Crijnen, Y. S., Nouwens, F., de Lau, L. M. L., Visch-Brink, E. G., van de Sandt-Koenderman, M. W. M. E., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., van den Berg, L. A., Lingsma, H. F., Roos, Y. B. W. E. M., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., & Dippel, D. W. J. (2016). Early effect of intra-arterial treatment in ischemic stroke on aphasia recovery in MR CLEAN. Neurology, 86(22), 2049-2055. https://doi.org/10.1212/WNL.0000000000002724
- Beumer, D., Rozeman, A. D., Nijeholt, G. J. L. A., Brouwer, P. A., Jenniskens, S. F. M., Algra, A., Boiten, J., Schonewille, W., van Oostenbrugge, R. J., Dippel, D. W. J., & van Zwam, W. H. (2016). The effect of age on outcome after intraarterial treatment in acute ischemic stroke: a MR CLEAN pretrial study. BMC Neurology, 16(1), Article 68. https://doi.org/10.1186/s12883-016-0592-5
- Douven, E., Schievink, S. H. J., Verhey, F. R. J., van Oostenbrugge, R. J., Aalten, P., Staals, J., & Köhler, S. (2016). The Cognition and Affect after Stroke - a Prospective Evaluation of Risks (CASPER) study: rationale and design. BMC Neurology, 16(1), Article 65. https://doi.org/10.1186/s12883-016-0588-1
- Vöö, S., Kwee, R. M., Sluimer, J. C., Schreuder, F. H. B. M., Wierts, R., Bauwens, M., Heeneman, S., Cleutjens, J. P. M., van Oostenbrugge, R. J., Daemen, J.-W. H., Daemen, M. J. A. P., Mottaghy, F. M., & Kooi, E. (2016). Imaging Intraplaque Inflammation in Carotid Atherosclerosis With F-18-Fluorocholine Positron Emission Tomography-Computed Tomography Prospective Study on Vulnerable Atheroma With Immunohistochemical Validation. Circulation-Cardiovascular Imaging, 9(5), Article e004467. https://doi.org/10.1161/CIRCIMAGING.115.004467
- Goyal, M., Menon, B. K., van Zwam, W. H., Dippel, D. W. J., Mitchell, P. J., Demchuk, A. M., Davalos, A., Majoie, C. B. L. M., van der Lugt, A., de Miquel, M. A., Donnan, G. R. A., Roos, Y. B. W. E. M., Bonafe, A., Jahan, R., Diener, H.-C., van den Berg, L. A., Levy, E. I., Berkhemer, O. A., Pereira, V. M., ... Jovin, T. G. (2016). Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet, 387(10029), 1723-1731. https://doi.org/10.1016/S0140-6736(16)00163-X
- Uiterwijk, R., Huijts, M., Staals, J., Rouhl, R. P. W., De Leeuw, P. W., Kroon, A. A., & Van Oostenbrugge, R. J. (2016). Endothelial Activation Is Associated With Cognitive Performance in Patients With Hypertension. American Journal of Hypertension, 29(4), 464-469. https://doi.org/10.1093/ajh/hpv122
- Broen, M. P. G., Marsman, V. A. M., Kuijf, M. L., Van Oostenbrugge, R. J., van Os, J., & Leentjens, A. F. G. (2016). Unraveling the Relationship between Motor Symptoms, Affective States and Contextual Factors in Parkinson's Disease: A Feasibility Study of the Experience Sampling Method. PLOS ONE, 11(3), Article e0151195. https://doi.org/10.1371/journal.pone.0151195
- van Overbeek, E. C., Staals, J., Knottnerus, I. L. H., ten Cate, H., & van Oostenbrugge, R. J. (2016). Plasma tPA-Activity and Progression of Cerebral White Matter Hyperintensities in Lacunar Stroke Patients. PLOS ONE, 11(3), Article e0150740. https://doi.org/10.1371/journal.pone.0150740

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