• 2017
    • Berkhemer, O. A., Borst, J., Kappelhof, M., Yoo, A. J., van den Berg, L. A., Fransen, P. S. S., Beumer, D., Schonewille, W. J., Nederkoorn, P. J., Wermer, M. J. H., Marquering, H. A., Lingsma, H. F., Roos, Y. B. W. E. M., van Oostenbrugge, R. J., Dippel, D. W. J., van Zwam, W. H., Majoie, C. B. L. M., Emmer, B. J., van der Lugt, A., & MR CLEAN Investigators (2017). Extracranial Carotid Disease and Effect of Intra-arterial Treatment in Patients With Proximal Anterior Circulation Stroke in MR CLEAN. Annals of Internal Medicine, 166(12), 867-875. https://doi.org/10.7326/M16-1536
    • van der Vorst, E. P. C., Maas, S. L., Ortega-Gomez, A., Hameleers, J. M. M., Bianchini, M., Asare, Y., Soehnlein, O., Döring, Y., Weber, C., & Megens, R. T. A. (2017). Functional Imaging of Arterial Cellular Recruitment and Lipid Extravasation. Bio-protocol, 7(12). https://doi.org/10.21769/BioProtoc.2344
    • Beumer, D., van Boxtel, T. H., Schipperen, S., van Zwam, W. H., Nijeholt, G. J. L. A., Brouwer, P. A., Jenniskens, S. F. M., Schonewille, W. J., Vos, J. A., van der Lugt, A., Roos, Y. B., Majoie, C. B., van Oostenbrugge, R. J., Dippel, D. W. J., & MR CLEAN Pretrial Investigators (2017). The relationship between interventionists' experience and clinical and radiological outcome in intra-arterial treatment for acute ischemic stroke. A MR CLEAN pretrial survey. Journal of the Neurological Sciences, 377, 97-101. https://doi.org/10.1016/j.jns.2017.04.002
    • Temmerman, L., Westra, M. M., Bot, I., van Vlijmen, B. J. M., Van Bree, N., Bot, M., Habets, K. L. L., Keulers, T. G. H., van der Vlag, J., Cotter, T. G., van Berkel, T. J. C., & Biessen, E. A. L. (2017). Leukocyte Bim deficiency does not impact atherogenesis in ldlr(-/-) mice, despite a pronounced induction of autoimmune inflammation. Scientific Reports, 7(1), Article 3086. https://doi.org/10.1038/s41598-017-02771-4
    • Liu, Y., Steinbusch, L. K. M., Nabben, M., Kapsokalyvas, D., van Zandvoort, M., Schonleitner, P., Antoons, G., Simons, P. J., Coumans, W. A., Geomini, A., Chanda, D., Glatz, J. F. C., Neumann, D., & Luiken, J. J. F. P. (2017). Palmitate-Induced Vacuolar-Type H(+)-ATPase Inhibition Feeds Forward Into Insulin Resistance and Contractile Dysfunction. Diabetes, 66(6), 1521-1534. https://doi.org/10.2337/db16-0727
    • Robaeys, W., Bektas, S., Boyne, J., van Empel, V., Uszko-Lencer, N., Knackstedt, C., & Brunner-La Rocca, H. P. (2017). Pulmonary and right ventricular dysfunction are frequently present in heart failure irrespective of left ventricular ejection fraction. Heart Asia, 9(2), 1-8. https://doi.org/10.1136/heartasia-2017-010914
    • Steffens, S., Winter, C., Schloss, M. J., Hidalgo, A., Weber, C., & Soehnlein, O. (2017). Circadian Control of Inflammatory Processes in Atherosclerosis and Its Complications. Arteriosclerosis Thrombosis and Vascular Biology, 37(6), 1022-1028. https://doi.org/10.1161/ATVBAHA.117.309374
    • Mulder, M. J. H. L., Berkhemer, O. A., Fransen, P. S. S., van den Berg, L. A., Lingsma, H. F., den Hertog, H. M., Staals, J., Jenniskens, S. F. M., van Oostenbrugge, R. J., van Zwam, W. H., Majoie, C. B. L. M., van der Lugt, A., Dippel, D. W. J., & MR CLEAN Investigators (2017). Does prior antiplatelet treatment improve functional outcome after intra-arterial treatment for acute ischemic stroke?International journal of stroke, 12(4), 368-376. https://doi.org/10.1177/1747493016677842
    • Bermudez, B., Dahl, T. B., Medina, I., Groeneweg, M., Holm, S., Montserrat-de la Paz, S., Rousch, M., Otten, J., Herias, V., Varela, L. M., Ranheim, T., Yndestad, A., Ortega-Gomez, A., Abia, R., Nagy, L., Aukrust, P., Muriana, F. J. G., Halvorsen, B., & Leonardus Biessen, E. A. (2017). Leukocyte Overexpression of Intracellular NAMPT Attenuates Atherosclerosis by Regulating PPAR gamma-Dependent Monocyte Differentiation and Function. Arteriosclerosis Thrombosis and Vascular Biology, 37(6), 1157-1167. https://doi.org/10.1161/ATVBAHA.116.308187
    • Uiterwijk, R., Staals, J., Huijts, M., de Leeuw, P. W., Kroon, A. A., & van Oostenbrugge, R. J. (2017). MRI progression of cerebral small vessel disease and cognitive decline in patients with hypertension. Journal of Hypertension, 35(6), 1263-1270. https://doi.org/10.1097/HJH.0000000000001294
    • Altintas, S., Dinh, T., Marcks, N. G. H. M., Kok, M., Aerts, A. J. J., Weijs, B., Blaauw, Y., Wildberger, J. E., Das, M., Kietselaer, B. L. J. H., & Crijns, H. J. G. M. (2017). Presence and extent of cardiac computed tomography angiography defined coronary artery disease in patients presenting with syncope. Netherlands Heart Journal, 25(6), 376-387. https://doi.org/10.1007/s12471-017-0970-7
    • Aarts, S. A. B. M., Seijkens, T. T. P., Kusters, P. J. H., van der Pol, S. M. A., Zarzycka, B., Heijnen, P. D. A. M., Beckers, L., den Toom, M., Gijbels, M. J. J., Boon, L., Weber, C., de Vries, H. E., Nicolaes, G. A. F., Dijkstra, C. D., Kooij, G., & Lutgens, E. (2017). Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation. Journal of Neuroinflammation, 14(1), Article 105. https://doi.org/10.1186/s12974-017-0875-9
    • Venema, E., Mulder, M. J. H. L., Roozenbeek, B., Broderick, J. P., Yeatts, S. D., Khatri, P., Berkhemer, O. A., Emmer, B. J., Roos, Y. B. W. E. M., Majoie, C. B. L. M., van Oostenbrugge, R. J., van Zwam, W. H., van der Lugt, A., Steyerberg, E. W., Dippel, D. W. J., & Lingsma, H. F. (2017). Selection of patients for intra-arterial treatment for acute ischaemic stroke: development and validation of a clinical decision tool in two randomised trials. BMJ, 357, Article j1710. https://doi.org/10.1136/bmj.j1710
    • Wilson, D., Seiffge, D. J., Traenka, C., Basir, G., Purrucker, J. C., Rizos, T., Sobowale, O. A., Sallinen, H., Yeh, S.-J., Wu, T. Y., Ferrigno, M., Houben, R., Schreuder, F. H. B. M., Perry, L. A., Tanaka, J., Boulanger, M., Salman, R. A.-S., Jaeger, H. R., Ambler, G., ... CROMIS-2 Collaborators (2017). Outcome of intracerebral hemorrhage associated with different oral anticoagulants. Neurology, 88(18), 1693-1700. https://doi.org/10.1212/WNL.0000000000003886
    • Neradova, A., Schumacher, S. P., Hubeek, I., Lux, P., Schurgers, L. J., & Vervloet, M. G. (2017). Phosphate binders affect vitamin K concentration by undesired binding, an in vitro study. Bmc Nephrology, 18(1), Article 149. https://doi.org/10.1186/s12882-017-0560-3
    • Osei, E., den Hertog, H. M., Berkhemer, O. A., Fransen, P. S. S., Roos, Y. B. W. E. M., Beumer, D., van Oostenbrugge, R. J., Schonewille, W. J., Boiten, J., Zandbergen, A. A. M., Koudstaal, P. J., MR CLEAN Investigators, van Zwam, W., & Dippel, D. W. J. (2017). Admission Glucose and Effect of Intra-Arterial Treatment in Patients With Acute Ischemic Stroke. Stroke, 48(5), 1299-1305. https://doi.org/10.1161/STROKEAHA.116.016071
    • Hauer, A. J., Ruigrok, Y. M., Algra, A., van Dijk, E. J., Koudstaal, P. J., Luijckx, G.-J., Nederkoorn, P. J., van Oostenbrugge, R. J., Visser, M. C., Wermer, M. J., Kappelle, L. J., Klijn, C. J. M., & Dutch Parelsnoer Inst-Cerebrovasc (2017). Age-Specific Vascular Risk Factor Profiles According to Stroke Subtype. Journal of the American Heart Association, 6(5), Article 005090. https://doi.org/10.1161/JAHA.116.005090
    • Bucker, A., Boers, A. M., Bot, J. C. J., Berkhemer, O. A., Lingsma, H. F., Yoo, A. J., Van Zwam, W. H., Van Oostenbrugge, R. J., Van der Lugt, A., Dippel, D. W. J., Roos, Y. B. W. E. M., Majoie, C. B. L. M., Marquering, H. A., MR CLEAN Trial Investigators, & Multictr Randomized Clinical Trial (2017). Associations of Ischemic Lesion Volume With Functional Outcome in Patients With Acute Ischemic Stroke 24-Hour Versus 1-Week Imaging. Stroke, 48(5), 1233-1240. https://doi.org/10.1161/STROKEAHA.116.015156
    • Vink, R. G., Roumans, N. J., Cajlakovic, M., Cleutjens, J. P. M., Boekschoten, M. V., Fazelzadeh, P., Vogel, M. A. A., Blaak, E. E., Mariman, E. C., van Baak, M. A., & Goossens, G. H. (2017). Diet-induced weight loss decreases adipose tissue oxygen tension with parallel changes in adipose tissue phenotype and insulin sensitivity in overweight humans. International Journal of Obesity, 41(5), 722-728. https://doi.org/10.1038/ijo.2017.38
    • Bektas, S., Franssen, F. M. E., van Empel, V., Uszko-Lencer, N., Boyne, J., Knackstedt, C., & Brunner-La Rocca, H. P. (2017). Impact of airflow limitation in chronic heart failure. Netherlands Heart Journal, 25(5), 335-342. https://doi.org/10.1007/s12471-017-0965-4
    • Uitterdijk, A., Springeling, T., Hermans, K. C. M., Merkus, D., de Beer, V. J., Gorsse-Bakker, C., Mokelke, E., Daskalopoulos, E. P., Wielopolski, P. A., Cleutjens, J. P. M., Blankesteijn, W. M., Prinzen, F. W., van der Giessen, W. J., van Geuns, R.-J. M., & Duncker, D. J. (2017). Intermittent pacing therapy favorably modulates infarct remodeling. Basic Research in Cardiology, 112(3), Article 28. https://doi.org/10.1007/s00395-017-0616-3
    • Kuppe, C., van Roeyen, C., Leuchtle, K., Kabgani, N., Vogt, M., Van Zandvoort, M., Smeets, B., Floege, J., Groene, H.-J., & Moellert, M. J. (2017). Investigations of Glucocorticoid Action in GN. Journal of the American Society of Nephrology, 28(5), 1408-1420. https://doi.org/10.1681/ASN.2016010060
    • Rodriguez-Calvo, R., Chanda, D., Oligschlaeger, Y., Miglianico, M., Coumans, W. A., Barroso, E., Tajes, M., Luiken, J. J. F. P., Glatz, J. F. C., Vazquez-Carrera, M., & Neumann, D. (2017). Small heterodimer partner (SHP) contributes to insulin resistance in cardiomyocytes. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1862(5), 541-551. https://doi.org/10.1016/j.bbalip.2017.02.006
    • Boers, A. M. M., Berkhemer, O. A., Slump, C. H., van Zwam, W. H., Roos, Y. B. W. E. M., van der Lugt, A., van Oostenbrugge, R. J., Yoo, A. J., Dippel, D. W. J., Marquering, H. A., Majoie, C. B. L. M., & MR CLEAN Trial Investigators (2017). Topographic distribution of cerebral infarct probability in patients with acute ischemic stroke: mapping of intra-arterial treatment effect. Journal of Neurointerventional Surgery, 9(5), 431-436. https://doi.org/10.1136/neurintsurg-2016-012387
    • Chanda, D., Oligschlaeger, Y., Geraets, I., Liu, Y., Zhu, X., Li, J., Nabben, M., Coumans, W., Luiken, J. J. F. P., Glatz, J. F. C., & Neumann, D. (2017). 2-Arachidonoylglycerol ameliorates inflammatory stress-induced insulin resistance in cardiomyocytes. Journal of Biological Chemistry, 292(17), 7105-7114. https://doi.org/10.1074/jbc.M116.767384
    • van Empel, V., Knackstedt, C., van Paassen, P., & Brunner-La Rocca, H.-P. (2017). Just air good enough in pulmonary hypertension?European Heart Journal, 38(15), 1169-1171. https://doi.org/10.1093/eurheartj/ehx117
    • van Haare, J., Kooi, M. E., van Teeffelen, J. W. G. E., Vink, H., Slenter, J., Cobelens, H., Strijkers, G. J., Koehn, D., Post, M. J., & van Bilsen, M. (2017). Metformin and sulodexide restore cardiac microvascular perfusion capacity in diet-induced obese rats. Cardiovascular Diabetology, 16(1), Article 47. https://doi.org/10.1186/s12933-017-0525-7
    • Joshi, F. R., Manavaki, R., Fryer, T. D., Figg, N. L., Sluimer, J. C., Aigbirhio, F. I., Davenport, A. P., Kirkpatrick, P. J., Warburton, E. A., & Rudd, J. H. F. (2017). Vascular Imaging With 18F-Fluorodeoxyglucose Positron Emission Tomography Is Influenced by Hypoxia. Journal of the American College of Cardiology, 69(14), 1873-1874. https://doi.org/10.1016/j.jacc.2017.01.050
    • van den Berg, L. A., Dijkgraaf, M. G. W., Berkhemer, O. A., Fransen, P. S. S., Beumer, D., Lingsma, H. F., Majoie, C. B. L. M., Dippel, D. W. J., van der Lugt, A., van Oostenbrugge, R. J., van Zwam, W. H., Roos, Y. B. W. E. M., & MR CLEAN Investigators (2017). Two-Year Outcome after Endovascular Treatment for Acute Ischemic Stroke. New England Journal of Medicine, 376(14), 1341-1349. https://doi.org/10.1056/NEJMoa1612136
    • van Bussel, F. C. G., Backes, W. H., Hofman, P. A. M., van Oostenbrugge, R. J., van Boxtel, M. P. J., Verhey, F. R. J., Steinbusch, H. W. M., Schram, M. T., Stehouwer, C. D. A., Wildberger, J. E., & Jansen, J. JFA. (2017). Cerebral pathology and cognition in diabetes: the merits of multiparametric neuroimaging. Frontiers in Neuroscience, 11(APR), Article 188. https://doi.org/10.3389/fnins.2017.00188
    • von Hundelshausen, P., Agten, S. M., Eckardt, V., Blanchet, X., Schmitt, M. M., Ippel, H., Neideck, C., Bidzhekov, K., Leberzammer, J., Wichapong, K., Faussner, A., Drechsler, M., Grommes, J., van Geffen, J. P., Li, H., Ortega-Gomez, A., Megens, R. T. A., Naumann, R., Dijkgraaf, I., ... Weber, C. (2017). Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation. Science Translational Medicine, 9(384), Article eaah6650. https://doi.org/10.1126/scitranslmed.aah6650
    • Steinbuch, J., van Dijk, A. C., Schreuder, F. H. B. M., Truijman, M. T. B., Hendrikse, J., Nederkoorn, P. J., van der Lugt, A., Hermeling, E., Hoeks, A. P. G., & Mess, W. H. (2017). Definition of common carotid wall thickness affects risk classification in relation to degree of internal carotid artery stenosis: the Plaque At RISK (PARISK) study. Cardiovascular Ultrasound, 15(1), Article 9. https://doi.org/10.1186/s12947-017-0097-4
    • Nijssen, E. C., Rennenberg, R. J., Nelemans, P. J., Essers, B. A., Janssen, M. M., Vermeeren, M. A., van Ommen, V., & Wildberger, J. E. (2017). Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial. Lancet, 389(10076), 1312-1322. https://doi.org/10.1016/S0140-6736(17)30057-0
    • Haitjema, S., Meddens, C. A., van der Laan, S. W., Kofink, D., Harakalova, M., Tragante, V., Asl, H. F., van Setten, J., Brandt, M. M., Bis, J. C., O'Donnell, C., Cheng, C., Hoefer, I. E., Waltenberger, J., Biessen, E., Jukema, J. W., Doevendans, P. A. F. M., Nieuwenhuis, E. E. S., Erdmann, J., ... METASTROKE Grp Int Stroke Genetics (2017). Additional Candidate Genes for Human Atherosclerotic Disease Identified Through Annotation Based on Chromatin Organization. Circulation : Cardiovascular Genetics, 10(2), Article 001664. https://doi.org/10.1161/CIRCGENETICS.116.001664
    • Mihl, C., Maas, M., Turek, J., Seehofnerova, A., Leijenaar, R. T. H., Kok, M., Lobbes, M. B. I., Wildberger, J. E., & Das, M. (2017). Contrast Media Administration in Coronary Computed Tomography Angiography - A Systematic Review. RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der Bildgebenden Verfahren, 189(4), 312-325. https://doi.org/10.1055/s-0042-121609
    • Soehnlein, O., Steffens, S., Hidalgo, A., & Weber, C. (2017). Neutrophils as protagonists and targets in chronic inflammation. Nature Reviews Immunology, 17(4), 248-261. https://doi.org/10.1038/nri.2017.10
    • Heeneman, S., & de Grave, W. (2017). Tensions in mentoring medical students toward self-directed and reflective learning in a longitudinal portfolio-based mentoring system - An activity theory analysis. Medical Teacher, 39(4), 368-376. https://doi.org/10.1080/0142159X.2017.1286308
    • Palau-Caballero, G., Walmsley, J., Van Empel, V., Lumens, J., & Delhaas, T. (2017). Why septal motion is a marker of right ventricular failure in pulmonary arterial hypertension: mechanistic analysis using a computer model. American Journal of Physiology-heart and Circulatory Physiology, 312(4), H691-H700. https://doi.org/10.1152/ajpheart.00596.2016
    • Cleutjens, F. A. H. M., Ponds, R. W. H. M., Spruit, M. A., Burgmans, S., Jacobs, H. I. L., Gronenschild, E. H. B. M., Staals, J., Franssen, F. M. E., Dijkstra, J. B., Vanfleteren, L. E. G. W., Hofman, P. A., Wouters, E. F. M., & Janssen, D. J. A. (2017). The Relationship between Cerebral Small Vessel Disease, Hippocampal Volume and Cognitive Functioning in Patients with COPD: An MRI Study. Frontiers in Aging Neuroscience, 9(MAR), Article 88. https://doi.org/10.3389/fnagi.2017.00088
    • Rademakers, T., van der Vorst, E. P. C., Daissormont, I. T. M. N., Otten, J. J. T., Theodorou, K., Theelen, T. L., Gijbels, M., Anisimov, A., Nurmi, H., Lindeman, J. H. N., Schober, A., Heeneman, S., Alitalo, K., & Biessen, E. A. L. (2017). Adventitial lymphatic capillary expansion impacts on plaque T cell accumulation in atherosclerosis. Scientific Reports, 7, Article 45263. https://doi.org/10.1038/srep45263
    • Asare, Y., Ommer, M., Azombo, F. A., Alampour-Rajabi, S., Sternkopf, M., Sanati, M., Gijbels, M. J., Schmitz, C., Sinitski, D., Tilstam, P. V., Lue, H., Gessner, A., Lange, D., Schmid, J. A., Weber, C., Dichgans, M., Jankowski, J., Pardi, R., de Winther, M. P. J., ... Bernhagen, J. (2017). Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo. Proceedings of the National Academy of Sciences of the United States of America, 114(13), E2766-E2775. https://doi.org/10.1073/pnas.1618411114
    • Hyafil, F., Pelisek, J., Laitinen, I., Schottelius, M., Mohring, M., Doering, Y., van der Vorst, E. P. C., Kallmayer, M., Steiger, K., Poschenrieder, A., Notni, J., Fischer, J., Baumgartner, C., Rischpler, C., Nekolla, S. G., Weber, C., Eckstein, H.-H., Wester, H.-J., & Schwaiger, M. (2017). Imaging the Cytokine Receptor CXCR4 in Atherosclerotic Plaques with the Radiotracer (68)Ga-Pentixafor for PET. Journal of Nuclear Medicine, 58(3), 499-506. https://doi.org/10.2967/jnumed.116.179663
    • van der Vorst, E. P. C., Zhao, Z., Rami, M., Holdt, L. M., Teupser, D., Steffens, S., & Weber, C. (2017). Contrasting effects of myeloid and endothelial ADAM17 on atherosclerosis development. Thrombosis and Haemostasis, 117(3), 644-646. https://doi.org/10.1160/TH16-09-0674
    • Zhang, C. E., Wong, S. M., Uiterwijk, R., Staals, J., Backes, W. H., Hoff, E. I., Schreuder, T., Jeukens, C. R. L. P. N., Jansen, J. F. A., & van Oostenbrugge, R. J. (2017). Intravoxel Incoherent Motion Imaging in Small Vessel Disease Microstructural Integrity and Microvascular Perfusion Related to Cognition. Stroke, 48(3), 658-663. https://doi.org/10.1161/STROKEAHA.116.015084
    • Sailer, A. M., Paulis, L., Vergoossen, L., Kovac, A. O., Wijnhoven, G., Schurink, G. W. H., Mees, B., Das, M., Wildberger, J. E., de Haan, M. W., & Jeukens, C. R. L. P. N. (2017). Real-Time Patient and Staff Radiation Dose Monitoring in IR Practice. Cardiovascular and Interventional Radiology, 40(3), 421-429. https://doi.org/10.1007/s00270-016-1526-8
    • Mulder, M. J. H. L., Venema, E., Roozenbeek, B., Broderick, J. P., Yeatts, S. D., Khatri, P., Berkhemer, O. A., Roos, Y. B. W. E. M., Majoie, C. B. L. M., van Oostenbrugge, R. J., van Zwam, W. H., van der Lugt, A., Steyerberg, E. W., Dippel, D. W. J., & Lingsma, H. F. (2017). Towards personalised intra- arterial treatment of patients with acute ischaemic stroke: a study protocol for development and validation of a clinical decision aid. BMJ Open, 7(3), Article 013699. https://doi.org/10.1136/bmjopen-2016-013699
    • Wagemans, B. A. J. M., van Zwam, W. H., Nelemans, P. J., van Oostenbrugge, R. J., & Postma, A. A. (2017). 4D-CTA improves diagnostic certainty and accuracy in the detection of proximal intracranial anterior circulation occlusion in acute ischemic stroke. PLOS ONE, 12(2), Article 0172356. https://doi.org/10.1371/journal.pone.0172356
    • Rowinska, Z., Koeppel, T. A., Sanati, M., Schelzig, H., Jankowski, J., Weber, C., Zernecke, A., & Liehn, E. A. (2017). Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation. PLOS ONE, 12(2), Article 0170644. https://doi.org/10.1371/journal.pone.0170644
    • Wouters, K., Gaens, K., Bijnen, M., Verboven, K., Jocken, J., Wetzels, S., Wijnands, E., Hansen, D., van Greevenbroek, M., Duijvestijn, A. M., Biessen, E. A. L., Blaak, E. E., Stehouwer, C. D. A., & Schalkwijk, C. G. (2017). Circulating classical monocytes are associated with CD11c(+) macrophages in human visceral adipose tissue. Scientific Reports, 7, Article 42665. https://doi.org/10.1038/srep42665