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CARIM's Confidential Contact Persons

CARIM's Confidential Contact Persons

27 November 2024

Dr Magdi Nagy (Dept of Biochemistry) and Prof. Peter de Leeuw (Dept of Internal Medicine) have been appointed as CARIM Confidential Contact Persons.

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ZonMw grant on appropriate palliative care

ZonMw grant on appropriate palliative care

27 November 2024

Prof. Marc Hemmelder (Dept of Internal Medicine) and his team received a ZonMw grant to promote early palliative care for dialysis patients who are non-waitlisted for transplantation.

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Carim Maastricht
Carim Maastricht

Jos Maessen

Professor

Prof. Jos Maessen joined a young Maastricht University community in 1978 and stayed there after graduation in Medicine, obtaining his PhD, and being trained as a cardiothoracic surgeon, to become professor and chief of the Department of Cardiothoracic surgery as well as Principal Investigator in CARIM in 2005. From a rather non-academic clinical department, his group turned into an important clinical partner for basic scientists within CARIM initiating and supporting many translational research projects. Apart from delivering the best possible care his team is convinced that this approach is the best and shortest way to innovate the cardiac surgical profession. Crossing borders leads to new opportunities. Surgeons and electrophysiologists developed hybrid treatment modalities for AF treatment with better results and new research opportunities. Similarly, in reconstructive surgery of the aorta and mitral valve, combining treatment with virtual reality, modeling and experimental imaging, outcome improved and the results raised new hypotheses for basis research.

Jos-maessen

Department of Cardiothoracic Surgery
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: 3.C2.023
T: +31(0)43 387 11 25

  • 2022
    • Zeemering, S., Isaacs, A., Winters, J., Maesen, B., Bidar, E., Dimopoulou, C., Guasch, E., Batlle, M., Haase, D., Hatem, S. N., Kara, M., Kääb, S., Mont, L., Sinner, M. F., Wakili, R., Maessen, J., Crijns, H. J. G. M., Fabritz, L., Kirchhof, P., ... Schotten, U. (2022). Atrial fibrillation in the presence and absence of heart failure enhances expression of genes involved in cardiomyocyte structure, conduction properties, fibrosis, inflammation, and endothelial dysfunction. Heart Rhythm, 19(12), 2115-2124. https://doi.org/10.1016/j.hrthm.2022.08.019
    • Olsthoorn, J. R., Heuts, S., Houterman, S., Roefs, M., Maessen, J. G., Nia, P. S., & Cardiothoracic Surgery Registration Committee of the Netherlands Heart Registration (2022). Does concomitant tricuspid valve surgery increase the risks of minimally invasive mitral valve surgery? A multicentre comparison based on data from The Netherlands Heart Registration. Journal of Cardiac Surgery, 37(12), 4362–4370. https://doi.org/10.1111/jocs.17004
    • van der Heijden, C. A. J., Weberndörfer, V., Luermans, J. G. L. M., Chaldoupi, M., van Kuijk, S. M. J., Vroomen, M., Bidar, E., Maessen, J. G., Pison, L., La Meir, M., & Maesen, B. (2022). Hybrid ablation of atrial fibrillation: A unilateral left-sided thoracoscopic approach. Journal of Cardiac Surgery, 37(12), 4630-4638. https://doi.org/10.1111/jocs.17144
    • Daemen, J. H. T., Coorens, N. A., Hulsewé, K. W. E., Maal, T. J. J., Maessen, J. G., Vissers, Y. L. J., & de Loos, E. R. (2022). Three-dimensional Surface Imaging for Clinical Decision Making in Pectus Excavatum. Seminars in Thoracic and Cardiovascular Surgery, 34(4), 1364-1373. https://doi.org/10.1053/j.semtcvs.2021.08.002
    • Yilmaz, A., Van Genechten, S., Claessens, J., Packlé, L., Maessen, J., & Kaya, A. (2022). A totally endoscopic approach for aortic valve surgery. European Journal of Cardio-Thoracic Surgery, 62(6), Article ezac467. https://doi.org/10.1093/ejcts/ezac467
    • van der Heijden, C. A. J., Segers, P., Masud, A., Weberndörfer, V., Chaldoupi, S.-M., Luermans, J. G. L. M., Bijvoet, G. P., Kietselaer, B. L. J. H., van Kuijk, S. M. J., Barenbrug, P. J. C., Maessen, J. G., Bidar, E., & Maesen, B. (2022). Unilateral Left-sided Thoracoscopic Ablation of Atrial Fibrillation Concomitant to Minimally Invasive Bypass Grafting of the Left Anterior Descending Artery. European Journal of Cardio-Thoracic Surgery, 62(5), Article ezac409. https://doi.org/10.1093/ejcts/ezac409
    • Ganizada, B., Heuts, S., Willems, C., Cortenraad, I., Tunnissen, W., Maessen, J. G., Bidar, E., & Natour, E. (2022). Aortic root replacement in severe left ventricular dysfunction: The added value of beating-heart surgery. Journal of Cardiac Surgery, 37(11), 3984-3987. https://doi.org/10.1111/jocs.16879
    • Marcuse, F., Hochstenbag, M., De Baets, M. H. V., Bootsma, G., Maat, A. P. W. M., Hoeijmakers, J. G. J., Keijzers, M., Abdul Hamid, M., De Ruysscher, D., & Maessen, J. G. (2022). Robotic Thymectomy for Thymomas: A Retrospective Follow-up Study in the Netherlands. Annals of Thoracic Surgery, 114(5), 1886-1894. https://doi.org/10.1016/j.athoracsur.2021.09.056
    • Moula, A. I., Romeo, J. L. R., Parise, G., Parise, O., Maessen, J. G., Natour, E., Bidar, E., & Gelsomino, S. (2022). The evolution of arch surgery: Frozen elephant trunk or conventional elephant trunk?Frontiers in Cardiovascular Medicine, 9, Article 999314. https://doi.org/10.3389/fcvm.2022.999314
    • Scheenstra, B., Bruninx, A., van Daalen, F., Stahl, N., Latuapon, E., Imkamp, M., Ippel, L., Duijsings-Mahangi, S., Smits, D., Townend, D., Bermejo, I., Dekker, A., Hochstenbach, L., Spreeuwenberg, M., Maessen, J., van 't Hof, A., & Kietselaer, B. (2022). Digital Health Solutions to Reduce the Burden of Atherosclerotic Cardiovascular Disease Proposed by the CARRIER Consortium. JMIR Cardio, 6(2), Article e37437. https://doi.org/10.2196/37437
    • Olsthoorn, J. R., Heuts, S., Houterman, S., Maessen, J. G., Nia, P. S., & Cardiothoracic Surgery Registration Committee of the Netherlands Heart Registration (2022). Minimally invasive approach compared to resternotomy for mitral valve surgery in patients with prior cardiac surgery: retrospective multicentre study based on the Netherlands Heart Registration. European Journal of Cardio-Thoracic Surgery, 62(5), Article ezac420. https://doi.org/10.1093/ejcts/ezac420
    • Kawczynski, M. J., Van De Walle, S., Maesen, B., Isaacs, A., Zeemering, S., Hermans, B., Vernooy, K., Maessen, J. G., Schotten, U., & Bidar, E. (2022). Preoperative P-wave parameters and risk of atrial fibrillation after cardiac surgery: a meta-analysis of 20,201 patients. Interactive Cardiovascular and Thoracic Surgery, 35(4), Article ivac220. https://doi.org/10.1093/icvts/ivac220
    • Ganushchak, Y. M., Kurniawati, E. R., van der Horst, I. C. C., van Kuijk, S. M. J., Weerwind, P. W., Lorusso, R., & Maessen, J. G. (2022). Patterns of oxygen debt repayment in cardiogenic shock patients sustained with extracorporeal life support: A retrospective study. Journal of Critical Care, 71, Article 154044. https://doi.org/10.1016/j.jcrc.2022.154044
    • Kurniawati, E. R., Teerenstra, S., Vranken, N. P. A., Sharma, A. S., Maessen, J. G., & Weerwind, P. W. (2022). Oxygen debt repayment in the early phase of veno-arterial extracorporeal membrane oxygenation: a cluster analysis. BMC Cardiovascular disorders, 22(1), Article 363. https://doi.org/10.1186/s12872-022-02794-4
    • Maesen, B., Verheule, S., Zeemering, S., La Meir, M., Nijs, J., Lumeij, S., Lau, D. H., Granier, M., Crijns, H. J., Maessen, J. G., Dhein, S., & Schotten, U. (2022). Endomysial fibrosis, rather than overall connective tissue content, is the main determinant of conduction disturbances in human atrial fibrillation. EP Europace, 24(6), 1015-1024. https://doi.org/10.1093/europace/euac026
    • Heuts, S., Kawczynski, M. J., Maessen, J. G., & Bidar, E. (2022). Does early surgery result in improved long-term survival compared to watchful waiting in patients with asymptomatic severe aortic regurgitation with preserved ejection fraction?Interactive Cardiovascular and Thoracic Surgery, 35(2), Article ivac080. https://doi.org/10.1093/icvts/ivac080
    • Kurniawati, E. R., van Kuijk, S. M. J., Vranken, N. P. A., Maessen, J. G., & Weerwind, P. W. (2022). Efficacy of Veno-Arterial Extracorporeal Life Support in Adult Patients with Refractory Cardiogenic Shock. Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 16, Article 11795484221113988. https://doi.org/10.1177/11795484221113988
    • Mariani, S., De Piero, M. E., Ravaux, J. M., Saelmans, A., Kawczynski, M. J., van Bussel, B. C. T., Di Mauro, M., Willers, A., Swol, J., Kowalewski, M., Li, T., Delnoij, T. S. R., van der Horst, I. C. C., Maessen, J., & Lorusso, R. (2022). Temporary mechanical circulatory support for COVID-19 patients: A systematic review of literature. Artificial Organs, 46(7), 1249-1267. https://doi.org/10.1111/aor.14261
    • Salden, F. C. W. M., Huntjens, P. R., Schreurs, R., Willemen, E., Kuiper, M., Wouters, P., Maessen, J. G., Bordachar, P., Delhaas, T., Luermans, J., Meine, M., Allaart, C. P., van Stipdonk, A. M. W., Prinzen, F. W., Lumens, J., & Vernooy, K. (2022). Pacing therapy for atrioventricular dromotropathy: a combined computational-experimental-clinical study. EP Europace, 24(5), 784-795. https://doi.org/10.1093/europace/euab248
    • Olsthoorn, J. R., Heuts, S., Houterman, S., Maessen, J. G., & Sardari Nia, P. (2022). Effect of minimally invasive mitral valve surgery compared to sternotomy on short- and long-term outcomes: a retrospective multicentre interventional cohort study based on Netherlands Heart Registration. European Journal of Cardio-Thoracic Surgery, 61(5), 1099-1106. https://doi.org/10.1093/ejcts/ezab507
    • Massimi, G., Matteucci, M., Kowalewski, M., Ronco, D., Chiarini, G., De Piero, M. E., Lo Coco, V., Maessen, J. G., Beghi, C., & Lorusso, R. (2022). Operative strategies for acute mitral regurgitation as a mechanical complication of myocardial infarction. Annals of Cardiothoracic Surgery, 11(3), 328-336. https://doi.org/10.21037/acs-2022-ami-0016
    • Heuts, S., Adriaans, B. P., Kawczynski, M. J., Daemen, J. H. T., Natour, E., Lorusso, R., Schalla, S., Maessen, J. G., Wildberger, J. E., Jacobs, M. J., Rylski, B., & Bidar, E. (2022). Extending Aortic Replacement Beyond the Proximal Arch in Acute Type A Aortic Dissection: A Meta-Analysis of Short Term Outcomes and Long Term Actuarial Survival. European Journal of Vascular and Endovascular Surgery, 63(5), 674-687. https://doi.org/10.1016/j.ejvs.2021.12.045
    • Angrisani, A., Houben, R., Marcuse, F., Hochstenbag, M., Maessen, J., De Ruysscher, D., & Peeters, S. (2022). "Radiotherapy for thymic epithelial tumors: What is the optimal dose? A systematic review.". Clinical and Translational Radiation Oncology, 34, 67-74. https://doi.org/10.1016/j.ctro.2022.03.005
    • Matteucci, M., Ronco, D., Ravaux, J. M., Massimi, G., Di Mauro, M., Houterman, S., Maessen, J., Beghi, C., Severgnini, P., Lorusso, R., & Cardiothoracic Surgery Registration Committee of the Netherlands Heart Registration (2022). Surgical repair of post-infarction ventricular free-wall rupture in the Netherlands: data from a nationwide registry. Annals of Cardiothoracic Surgery, 11(3), 310-318. https://doi.org/10.21037/acs-2021-ami-10
    • van Herpt, T. T. W., Timmermans, S. A. M. E. G., van Mook, W. N. K. A., van Bussel, B. C. T., van der Horst, I. C. C., Maessen, J. G., Natour, E., van Paassen, P., & Heuts, S. (2022). Postsurgical Thrombotic Microangiopathy and Deregulated Complement. Journal of Clinical Medicine, 11(9), Article 2501. https://doi.org/10.3390/jcm11092501
    • van der Heijden, C. A. J., Verheule, S., Olsthoorn, J. R., Mihl, C., Poulina, L., van Kuijk, S. M. J., Heuts, S., Maessen, J. G., Bidar, E., & Maesen, B. (2022). Postoperative atrial fibrillation and atrial epicardial fat: Is there a link?IJC Heart and Vasculature, 39, Article 100976. https://doi.org/10.1016/j.ijcha.2022.100976
    • Marcuse, F., Brandts, L., Moens, D., Damoiseaux, J., Hochstenbag, M., Hoeijmakers, J. G. J., Maessen, J. G., & De Baets, M. (2022). The association between anti-acetylcholine receptor antibody level and clinical improvement in myasthenia gravis. European Journal of Neurology, 29(4), 1187-1197. https://doi.org/10.1111/ene.15238
    • de Loos, E. R., Daemen, J. H. T., Pennings, A. J., Heuts, S., Maessen, J. G., Hulsewe, K. W. E., & Vissers, Y. L. J. (2022). Minimally invasive repair of pectus excavatum by the Nuss procedure: The learning curve. Journal of Thoracic and Cardiovascular Surgery, 163(3), 828-837.e4. https://doi.org/10.1016/j.jtcvs.2020.11.154
    • Heuts, S., Makhoul, M., Mansouri, A. N., Taccone, F. S., Obeid, A., Belliato, M., Broman, L. M., Malfertheiner, M., Meani, P., Raffa, G. M., Delnoij, T., Maessen, J., Bolotin, G., & Lorusso, R. (2022). Defining and understanding the "extra-corporeal membrane oxygenation gap" in the veno-venous configuration: Timing and causes of death. Artificial Organs, 46(3), 349-361. https://doi.org/10.1111/aor.14058
    • Maesen, B., van der Heijden, C. A. J., Bidar, E., Vos, R., Athanasiou, T., & Maessen, J. G. (2022). Patient-reported quality of life after stand-alone and concomitant arrhythmia surgery: a systematic review and meta-analysis. Interactive Cardiovascular and Thoracic Surgery, 34(3), 339-348. Article 282. https://doi.org/10.1093/icvts/ivab282
    • Hendrix, R. H. J., Kurniawati, E. R., Schins, S. F. C., Maessen, J. G., & Weerwind, P. W. (2022). Dynamic oxygenator blood volume during prolonged extracorporeal life support. PLOS ONE, 17(2), Article e0263360. https://doi.org/10.1371/journal.pone.0263360
    • Ravaux, J. M., Van Kuijk, S. M. J., Di Mauro, M., Vernooy, K., Bidar, E., Van't Hof, A. W., Veenstra, L., Kats, S., Houterman, S., Maessen, J. G., Lorusso, R., & THI Registration Committee of The Netherlands Heart Registration (2022). Incidence and Predictors of Permanent Pacemaker Implantation after Transcatheter Aortic Valve Procedures: Data of The Netherlands Heart Registration (NHR). Journal of Clinical Medicine, 11(3), Article 560. https://doi.org/10.3390/jcm11030560
    • Bruninx, A., Scheenstra, B., Dekker, A., Maessen, J., Hof, A. V., Kietselaer, B., & Bermejo, I. (2022). Using clinical prediction models to personalise lifestyle interventions for cardiovascular disease prevention: A systematic literature review. Preventive Medicine Reports, 25, Article 101672. https://doi.org/10.1016/j.pmedr.2021.101672
    • Cornips, E. M. J., Maesen, B., Geskes, G., Maessen, J. G., Beuls, E. A. M., & Menovsky, T. (2022). T3-T4 Disc Herniations: Clinical Presentation, Imaging, and Transaxillary Approach. World Neurosurgery, 158, e984-e995. https://doi.org/10.1016/j.wneu.2021.11.128
    • Heuts, S., Denessen, E. J. S., Daemen, J. H. T., Vroemen, W. H. M., Sels, J. W., Segers, P., Bekers, O., Hof, A. W. J. V., Maessen, J. G., van der Horst, I. C. C., & Mingels, A. M. A. (2022). Meta-Analysis Evaluating High-Sensitivity Cardiac Troponin T Kinetics after Coronary Artery Bypass Grafting in Relation to the Current Definitions of Myocardial Infarction. American Journal of Cardiology, 163, 25-31. https://doi.org/10.1016/j.amjcard.2021.09.049
    • de Jong, M. M. J., Parise, O., Matteucci, F., Rutten, M., Devos, M., Romano, M., Micali, L. R., Parise, G., Maessen, J. G., & Gelsomino, S. (2022). Aortic flow below and visceral circulation during aortic counterpulsation: Evaluation of an in vitro model. Perfusion, 37(1), 69-77. Article 0267659120978641. https://doi.org/10.1177/0267659120978641
    • Scheenstra, B., Princée, A. M. A., Imkamp, M. S. V., Kietselaer, B., Ganushchak, Y. M., Van't Hof, A. W. J., & Maessen, J. G. (2022). Last-minute cancellation of adult patients scheduled for cardiothoracic surgery in a large Dutch tertiary care centre. European Journal of Cardio-Thoracic Surgery, 61(1), 225-232. https://doi.org/10.1093/ejcts/ezab246
    • Laven, I. E. W. G., Daemen, J. H. T., Jansen, Y. J. L., Janssen, N., Franssen, A. J. P. M., Heuts, S., Maessen, J. G., van den Broek, F. J. C., Hulsewe, K. W. E., Vissers, Y. L. J., & de Loos, E. R. (2022). Thoracic surgery in the Netherlands. Journal of Thoracic Disease, 14(10), 4173-4186. https://doi.org/10.21037/jtd-22-482
  • 2021
    • Tetta, C., Montrone, G., Longhi, A., Rocca, M., Londero, F., Parise, G., Parise, O., Maessen, J. G., Miceli, M., & Gelsomino, S. (2021). Chemosensitivity of Lung Metastatic High-Grade Synovial Sarcoma. Journal of Clinical Medicine, 10(24), Article 5956. https://doi.org/10.3390/jcm10245956
    • Bidar, E., Zeemering, S., Gilbers, M., Isaacs, A., Verheule, S., Zink, M. D., Maesen, B., Bramer, S., Kawczynski, M., Van Gelder, I. C., Crijns, H. J. G. M., Maessen, J. G., & Schotten, U. (2021). Clinical and electrophysiological predictors of device-detected new-onset atrial fibrillation during 3 years after cardiac surgery. EP Europace, 23(12), 1922-1930. https://doi.org/10.1093/europace/euab136
    • Nijs, J., Vangelder, B., Tanaka, K., Gelsomino, S., Van Loo, I., La Meir, M., Maessen, J., & Kietselaer, B. L. J. H. (2021). Geometric characteristics of bicuspid aortic valves. JTCVS Techniques, 10, 200-215. https://doi.org/10.1016/j.xjtc.2021.08.032
    • Marcuse, F., Peeters, S., Herman, K., Vaassen, F., Van Elmpt, W., Maat, A. P. W. M., Praag, J., Billiet, C., Van Schil, P., Lambrecht, M., Van Raemdonck, D., Cao, K., Grigoroiu, M., Girard, N., Hochstenbag, M., Maessen, J., & De Ruysscher, D. (2021). Optimal delineation of the clinical target volume for thymomas in the post-resection setting: A multi-center study. Radiotherapy and Oncology, 165, 8-13. https://doi.org/10.1016/j.radonc.2021.10.007
    • Ravaux, J. M., Di Mauro, M., Vernooy, K., Kats, S., Mariani, S., Ronco, D., Dato, G. A., Simons, J., Van't Hof, A. W., Maessen, J. G., & Lorusso, R. (2021). Permanent pacemaker implantation following transcatheter aortic valve implantation using self-expandable, balloon-expandable, or mechanically expandable devices: a network meta-analysis. EP Europace, 23(12), 1998-2009. https://doi.org/10.1093/europace/euab209
    • Suverein, M. M., Shaw, D., Lorusso, R., Delnoij, T. S. R., Essers, B., Weerwind, P. W., Townend, D., van de Poll, M. C. G., & Maessen, J. G. (2021). Ethics of ECPR research. Resuscitation, 169, 136-142. https://doi.org/10.1016/j.resuscitation.2021.08.007
    • Lux, A., Veenstra, L. F., Kats, S., Dohmen, W., Maessen, J. G., Hof, A. W. J. V., & Maesen, B. (2021). Urgent transcatheter aortic valve implantation in an all-comer population: a single-centre experience. BMC Cardiovascular disorders, 21(1), Article 550. https://doi.org/10.1186/s12872-021-02347-1
    • Gandhi, S., Witten, A., De Majo, F., Gilbers, M., Maessen, J., Schotten, U., de Windt, L. J., & Stoll, M. (2021). Evolutionarily conserved transcriptional landscape of the heart defining the chamber specific physiology. Genomics, 113(6), 3782-3792. https://doi.org/10.1016/j.ygeno.2021.09.002
    • Kawczynski, M. J., Gilbers, M., Van de Walle, S., Schalla, S., Crijns, H. J., Maessen, J. G., Schotten, U., Maesen, B., & Bidar, E. (2021). Role of pre-operative transthoracic echocardiography in predicting post-operative atrial fibrillation after cardiac surgery: a systematic review of the literature and meta-analysis. EP Europace, 23(11), 1731-1743. https://doi.org/10.1093/europace/euab095
    • de Loos, E. R., Daemen, J. H. T., Coorens, N. A., Maessen, J. G., Vissers, Y. L. J., & Hulsewe, K. W. E. (2021). Sternal elevation by the crane technique during pectus excavatum repair: A quantitative analysis. JTCVS Techniques, 9, 167-175. https://doi.org/10.1016/j.xjtc.2021.05.028
    • Ravaux, J. M., Van Kuijk, S. M. J., Di Mauro, M., Vernooy, K., Bidar, E., Mariani, S., Dato, G. A., Van't Hof, A. W., Veenstra, L., Kats, S., Houterman, S., Maessen, J. G., Lorusso, R., & Cardiothoracic Surgery Registration Committee of the Netherlands Heart Registration (2021). Incidence and predictors of permanent pacemaker implantation after surgical aortic v alve replacement: Data of the Netherlands Heart Registration (NHR). Journal of Cardiac Surgery, 36(10), 3519-3527. https://doi.org/10.1111/jocs.15803
Overview