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CARIM's Confidential Contact Persons

CARIM's Confidential Contact Persons

27 November 2024

Dr Magdi Nagy (Dept of Biochemistry) and Prof. Peter de Leeuw (Dept of Internal Medicine) have been appointed as CARIM Confidential Contact Persons.

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ZonMw grant on appropriate palliative care

ZonMw grant on appropriate palliative care

27 November 2024

Prof. Marc Hemmelder (Dept of Internal Medicine) and his team received a ZonMw grant to promote early palliative care for dialysis patients who are non-waitlisted for transplantation.

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Carim Maastricht
Carim Maastricht

Jos Maessen

Professor

Prof. Jos Maessen joined a young Maastricht University community in 1978 and stayed there after graduation in Medicine, obtaining his PhD, and being trained as a cardiothoracic surgeon, to become professor and chief of the Department of Cardiothoracic surgery as well as Principal Investigator in CARIM in 2005. From a rather non-academic clinical department, his group turned into an important clinical partner for basic scientists within CARIM initiating and supporting many translational research projects. Apart from delivering the best possible care his team is convinced that this approach is the best and shortest way to innovate the cardiac surgical profession. Crossing borders leads to new opportunities. Surgeons and electrophysiologists developed hybrid treatment modalities for AF treatment with better results and new research opportunities. Similarly, in reconstructive surgery of the aorta and mitral valve, combining treatment with virtual reality, modeling and experimental imaging, outcome improved and the results raised new hypotheses for basis research.

Jos-maessen

Department of Cardiothoracic Surgery
P. Debyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
Room number: 3.C2.023
T: +31(0)43 387 11 25

  • 2015
    • Keijzers, M., de Baets, M., Hochstenbag, M., Abdul-Hamid, M., zur Hausen, A., van der Linden, M., Kuks, J., Verschuuren, J., Kessels, F., Dingemans, A.-M. C., & Maessen, J. (2015). Robotic thymectomy in patients with myasthenia gravis: neurological and surgical outcomes. European Journal of Cardio-Thoracic Surgery, 48(1), 40-45. https://doi.org/10.1093/ejcts/ezu352
    • Kumar, N., Dinh, T., Phan, K., Timmermans, C., Philippens, S., Dassen, W., Vranken, N., Pison, L., Maessen, J., & Crijns, H. J. (2015). Adenosine testing after second-generation cryoballoon ablation (ATSCA) study improves clinical success rate for atrial fibrillation. EP Europace, 17(6), 871-876. https://doi.org/10.1093/europace/euu352
    • Delnoij, T. S. R., Veldhuijzen, G., Strauch, U., Van Mook, W. N. K. A., Bergmans, D. C. J. J., Bouman, E. A., Lance, M. D., Smets, M., Breedveld, P., Ganushchak, Y. M., Weerwind, P., Kats, S., Roekaerts, P. M., Maessen, J., & Donker, D. W. (2015). Mobile respiratory rescue support by off-centre initiation of extracorporeal membrane oxygenation. Perfusion, 30(3), 255-259. https://doi.org/10.1177/0267659114540735
    • Severdija, E. E., Gommer, E. D., Weerwind, P. W., Reulen, J. P. H., Mess, W. H., & Maessen, J. G. (2015). Assessment of dynamic cerebral autoregulation and cerebral carbon dioxide reactivity during normothermic cardiopulmonary bypass. Medical & Biological Engineering & Computing, 53(3), 195-203. https://doi.org/10.1007/s11517-014-1225-z
    • Kumar, N., Bonizzi, P., Pison, L., Phan, K., Lankveld, T., Maessen, B., La Meir, M., Gelsomino, S., Maessen, J., & Crijns, H. (2015). Impact of hybrid procedure on P wave duration for atrial fibrillation ablation. Journal of Interventional Cardiac Electrophysiology, 42(2), 91-99. https://doi.org/10.1007/s10840-014-9969-9
    • Sharma, A. S., Weerwind, P. W., Ganushchak, Y. M., Donker, D. W., & Maessen, J. G. (2015). Towards a proactive therapy utilizing the modern spectrum of extracorporeal life support: a single-centre experience. Perfusion, 30(2), 113-118. https://doi.org/10.1177/0267659114530455
    • Kumar, N., Dinh, T., Magdi Abbas, M., Phan, K., Manusama, R., Philippens, S., Maessen, J., & Timmermans, C. (2015). Failure to reach the optimal temperature during cryoablation due to refrigerant cylinder problem. Research in cardiovascular medicine, 4(1), Article e25592. https://doi.org/10.5812/cardiovascmed.25592
    • Poels, T. T., Houthuizen, P., Van Garsse, L. A. F. M., Hamad, M. A. S., Maessen, J. G., Prinzen, F. W., & Van Straten, A. H. M. (2015). Frequency and prognosis of new bundle branch block induced by surgical aortic valve replacement. European Journal of Cardio-Thoracic Surgery, 47(2), E47-E53. https://doi.org/10.1093/ejcts/ezu435
    • Kumar, N., Kevin Phan, Pison, L., & Maessen, J. (2015). Re: Clinical Characteristics and Prognostic Significance of Chronic Obstructive Pulmonary Disease in Patients With Atrial Fibrillation: Results From a Multicenter Atrial Fibrillation Registry Study. Journal of the American Medical Directors Association, 16(1), 82-83. https://doi.org/10.1016/j.jamda.2014.08.015
    • Kuklik, P., Zeemering, S., Maesen, B., Maessen, J., Crijns, H. J., Verheule, S., Ganesan, A. N., & Schotten, U. (2015). Reconstruction of Instantaneous Phase of Unipolar Atrial Contact Electrogram Using a Concept of Sinusoidal Recomposition and Hilbert Transform. Ieee Transactions on Biomedical Engineering, 62(1), 296-302. https://doi.org/10.1109/TBME.2014.2350029
  • 2014
    • Kuklik, P., Bidar, E., Gharaviri, A., Maessen, J., & Schotten, U. (2014). Application of phase coherence in assessment of spatial alignment of electrodes during simultaneous endocardial-epicardial direct contact mapping of atrial fibrillation. EP Europace, 16 (Suppl 4), iv135-iv140. https://doi.org/10.1093/europace/euu247
    • Kumar, N., Pison, L., La Meir, M., Maessen, J., & Crijns, H. J. (2014). Hybrid approach to atrial fibrillation ablation using bipolar radiofrequency devices epicardially and cryoballoon endocardially. Interactive Cardiovascular and Thoracic Surgery, 19(4), 590-594. https://doi.org/10.1093/icvts/ivu189
    • Beckerman, Z., Azran, A., Cohen, O., Nir, R.-R., Maessen, J. G., Bianco-Peled, H., & Bolotin, G. (2014). A Novel Amiodarone-Eluting Biological Glue for Reducing Postoperative Atrial Fibrillation: First Animal Trial. Journal of Cardiovascular Pharmacology and Therapeutics, 19(5), 481-491. https://doi.org/10.1177/1074248414527640
    • Kumar, N., Pison, L., la Meir, M., & Maessen, J. (2014). Direct visualization of pulmonary vein stenosis after previous catheter ablation. Heart Rhythm, 11(9), 1602-1602. https://doi.org/10.1016/j.hrthm.2013.10.052
    • van Breugel, H. N. A. M., Gelsomino, S., de Vos, C. B., Accord, R. E., Tieleman, R. G., Luca, F., Rostagno, C., Renzulli, A., Parise, O., Lorusso, R., Crijns, H. J. G. M., & Maessen, J. G. (2014). Maintenance of sinus rhythm after electrical cardioversion for recurrent atrial fibrillation following mitral valve surgery with or without associated radiofrequency ablation. International Journal of Cardiology, 175(2), 290-296. https://doi.org/10.1016/j.ijcard.2014.05.010
    • Vrolix, K., Fraussen, J., Losen, M., Stevens, J., Lazaridis, K., Molenaar, P. C., Somers, V., Alma Bracho, M., Le Panse, R., Stinissen, P., Berrih-Aknin, S., Maessen, J. G., Van Garsse, L., Buurman, W. A., Tzartos, S. J., De Baets, M. H., & Martinez-Martinez, P. (2014). Clonal heterogeneity of thymic B cells from early-onset myasthenia gravis patients with antibodies against the acetylcholine receptor. Journal of Autoimmunity, 52, 101-112. https://doi.org/10.1016/j.jaut.2013.12.008
    • van Middendorp, L. B., Strik, M., Houthuizen, P., Kuiper, M., Maessen, J. G., Auricchio, A., & Prinzen, F. (2014). Electrophysiological and haemodynamic effects of vernakalant and flecainide in dyssynchronous canine hearts. EP Europace, 16(8), 1249-1256. https://doi.org/10.1093/europace/eut429
    • Kumar, N., Timmermans, C., Das, M., Pison, L., Maessen, J., & Crijns, H. (2014). Re: CT imaging of complications of catheter ablation for atrial fibrillation. Clinical Radiology, 69(8), e367-8. https://doi.org/10.1016/j.crad.2014.04.009
    • Vranken, N. P. A., Weerwind, P. W., Barenbrug, P. J. C., Teerenstra, S., Ganushchak, Y. M., & Maessen, J. G. (2014). The role of patient's profile and allogeneic blood transfusion in development of post-cardiac surgery infections: a retrospective study. Interactive Cardiovascular and Thoracic Surgery, 19(2), 232-238. https://doi.org/10.1093/icvts/ivu096
    • Nijs, J., Gelsomino, S., Kietselaer, B. B., Parise, O., Lucà, F., Maessen, J. G., & Meir, M. L. (2014). 3D-echo in preoperative assessment of aortic cusps effective height. World journal of cardiology, 6(7), 689-91. https://doi.org/10.4330/wjc.v6.i7.689
    • Poels, T. T., Houthuizen, P., Van Garsse, L. A. F. M., Maessen, J. G., de Jaegere, P., & Prinzen, F. W. (2014). Transcatheter Aortic Valve Implantation-Induced Left Bundle Branch Block: Causes and Consequences. Journal of Cardiovascular Translational Research, 7(4), 395-405. https://doi.org/10.1007/s12265-014-9560-x
    • Krul, S. P. J., Pison, L., La Meir, M., Driessen, A. H. G., Wilde, A. A. M., Maessen, J. G., De Mol, B. A. J. M., Crijns, H. J. G. M., & de Groot, J. R. (2014). Epicardial and endocardial electrophysiological guided thoracoscopic surgery for atrial fibrillation: A multidisciplinary approach of atrial fibrillation ablation in challenging patients. International Journal of Cardiology, 173(2), 229-235. https://doi.org/10.1016/j.ijcard.2014.02.043
    • Keijzers, M., Dingemans, A.-M. C., Blaauwgeers, H., van Suylen, R. J., Hochstenbag, M., van Garsse, L., Accord, R., de Baets, M., & Maessen, J. (2014). 8 Years' experience with robotic thymectomy for thymomas. Surgical endoscopy and other interventional techniques, 28(4), 1202-1208. https://doi.org/10.1007/s00464-013-3309-5
    • Sharma, A. S., Weerwind, P. W., & Maessen, J. G. (2014). EXTRACORPOREAL MEMBRANE OXYGENATION RESUSCITATION IN ADULT PATIENTS WITH REFRACTORY SEPTIC SHOCK. Journal of Thoracic and Cardiovascular Surgery, 147(4), 1441-1442. https://doi.org/10.1016/j.jtcvs.2013.12.069
    • Geenen, I. L., Verbruggen, S., Molin, D. G., Spronk, H. M., Maessen, J. G., Meesters, B., Schurink, G. W., & Post, M. J. (2014). Phenotypic Fitness of Primary Endothelial Cells Cultured from Patients with High Cardiovascular Risk or Chronic Kidney Disease for Vascular Tissue Engineering. Tissue Engineering, 20(5-6), 1049-1059. https://doi.org/10.1089/ten.tea.2013.0163
    • van Breugel, H. N. A. M., Gelsomino, S., Lozekoot, P. W. J., Accord, R. E., Luca, F., Parise, O., Crijns, H. J. G. M., & Maessen, J. G. (2014). Guideline adherence in antithrombotic treatment after concomitant ablation surgery in atrial fibrillation patients. Interactive Cardiovascular and Thoracic Surgery, 18(3), 313-320. https://doi.org/10.1093/icvts/ivt522
    • Gelsomino, S., Van Breugel, H. N. A. M., Pison, L., Parise, O., Crijns, H. J. G. M., Wellens, F., Maessen, J. G., & La Meir, M. (2014). Hybrid thoracoscopic and transvenous catheter ablation of atrial fibrillation. European Journal of Cardio-Thoracic Surgery, 45(3), 401-407. https://doi.org/10.1093/ejcts/ezt385
    • Hazebroek, M. R., van Paassen, P., Weerwind, P. W., Cooper, L. T. . J., Uriel, N., Caliskan, K., de Vries, B., Maessen, J. G., Autschbach, R., Heymans, S., & Donker, D. W. (2014). A passionate endurance cyclist ultimately survives sudden death in right ventricular giant cell myocarditis. International Journal of Cardiology, 170(3), E74-E75. https://doi.org/10.1016/j.ijcard.2013.11.028
    • Pison, L., Gelsomino, S., Luca, F., Parise, O., Maessen, J. G., Crijns, H. J. G. M., & La Meir, M. (2014). Effectiveness and safety of simultaneous hybrid thoracoscopic and endocardial catheter ablation of lone atrial fibrillation. Annals of Cardiothoracic Surgery, 3(1), 38-44. https://doi.org/10.3978/j.issn.2225-319X.2013.12.10
    • Simons, A. P., Lindelauf, A. A. M. A., Ganushchak, Y. M., Maessen, J. G., & Weerwind, P. W. (2014). Efficacy and safety of strategies to preserve stable extracorporeal life support flow during simulated hypovolemia. Perfusion, 29(1), 18-24. https://doi.org/10.1177/0267659113502833
    • van Middendorp, L. B., Strik, M., Houthuizen, P., Kuiper, M., Maessen, J. G., Auricchio, A., & Prinzen, F. W. (2014). Electrophysiological and Hemodynamic Effects of Vernakalant and Flecainide During Cardiac Resynchronization in Dyssynchronous Canine Hearts. Journal of Cardiovascular Pharmacology, 63(1), 25-32. https://doi.org/10.1097/FJC.0000000000000020
    • Gelsomino, S., Luca, F., Rao, C. M., Parise, O., Pison, L., Wellens, F., Maessen, J., & La Meir, M. (2014). Improvement of left atrial function and left atrial reverse remodeling after surgical treatment of atrial fibrillation. Annals of Cardiothoracic Surgery, 3(1), 70-4. https://doi.org/10.3978/j.issn.2225-319X.2013.12.03
    • Kumar, N., Timmermans, C., Das, M., Dassen, W., Philippens, S., Maessen, J., & Crijns, H. (2014). Hemoptysis after cryoablation for atrial fibrillation: truth or just a myth?Chest, 146(5). https://doi.org/10.1378/chest.14-1600
    • Nijs, J., Gelsomino, S., Luca, F., Parise, O., Maessen, J., & La Meir, M. (2014). Unreliability of aortic size index to predict risk of aortic dissection in a patient with Turner syndrome. World Journal of Cardiology , 6(5). https://doi.org/10.4330/wjc.v6.i5.349
  • 2013
    • Verberkmoes, N. J., Mokhles, M. M., Bramer, S., van Straten, A. H. M., ter Woorst, J. F., Maessen, J. G., & Berreklouw, E. (2013). Long-Term Clinical Outcome of the Symmetry Aortic Connector System in Off-Pump Coronary Artery Bypass Grafting. Thoracic and Cardiovascular Surgeon, 61(8), 669-675. https://doi.org/10.1055/s-0032-1311539
    • Nuis, R.-J., Sinning, J.-M., Rodes-Cabau, J., Gotzmann, M., van Garsse, L., Kefer, J., Bosmans, J., Yong, G., Dager, A. E., Revilla-Orodea, A., Urena, M., Nickenig, G., Werner, N., Maessen, J., Astarci, P., Perez, S., Benitez, L. M., Amat-Santos, I. J., Lopez, J., ... de Jaegere, P. P. (2013). Prevalence, Factors Associated With, and Prognostic Effects of Preoperative Anemia on Short- and Long-Term Mortality in Patients Undergoing Transcatheter Aortic Valve Implantation. Circulation-Cardiovascular Interventions, 6(6), 625-634. https://doi.org/10.1161/CIRCINTERVENTIONS.113.000409
    • Gelsomino, S., Luca, F., Parise, O., Lorusso, R., Rao, C. M., Vizzardi, E., Gensini, G. F., & Maessen, J. G. (2013). Longitudinal strain predicts left ventricular mass regression after aortic valve replacement for severe aortic stenosis and preserved left ventricular function. Heart and Vessels, 28(6), 775-784. https://doi.org/10.1007/s00380-012-0308-8
    • Weerwind, P. W., van der Veen, F., Gelsomino, S., Nagaraj, N. G., Parise, O., Lorusso, R., Gensini, G. F., & Maessen, J. G. (2013). Cytokine removal on extracorporeal life support for treatment of acute endotoxemia: A randomized controlled animal study. International Journal of Cardiology, 168(5), 4699-4704. https://doi.org/10.1016/j.ijcard.2013.07.175
    • Maesen, B., Zeemering, S., Afonso, C., Eckstein, J., Burton, R. A. B., van Hunnik, A., Stuckey, D. J., Tyler, D., Maessen, J., Grau, V., Verheule, S., Kohl, P., & Schotten, U. (2013). Rearrangement of Atrial Bundle Architecture and Consequent Changes in Anisotropy of Conduction Constitute the 3-Dimensional Substrate for Atrial Fibrillation. Circulation-Arrhythmia and Electrophysiology, 6(5), 967-975. https://doi.org/10.1161/CIRCEP.113.000050
    • van Garsse, L., Gelsomino, S., Luca, F., Parise, O., Lorusso, R., Cheriex, E., Caciolli, S., Vizzardi, E., Rao, C. M., Carella, R., Gensini, G. F., & Maessen, J. (2013). Left ventricular dyssynchrony is associated with recurrence of ischemic mitral regurgitation after restrictive annuloplasty. International Journal of Cardiology, 168(1), 176-184. https://doi.org/10.1016/j.ijcard.2012.09.098
    • La Meir, M., Gelsomino, S., Luca, F., Pison, L., Parise, O., Colella, A., Gensini, G. F., Crijns, H., Wellens, F., & Maessen, J. G. (2013). Minimally invasive surgical treatment of lone atrial fibrillation: Early results of hybrid versus standard minimally invasive approach employing radiofrequency sources. International Journal of Cardiology, 167(4), 1469-1475. https://doi.org/10.1016/j.ijcard.2012.04.044
    • Bramer, S., ter Woorst, F. J., van Geldorp, M. W. A., van den Broek, K. C., Maessen, J. G., Berreklouw, E., & van Straten, A. H. (2013). Does new-onset postoperative atrial fibrillation after coronary artery bypass grafting affect postoperative quality of life?Journal of Thoracic and Cardiovascular Surgery, 146(1), 114-118. https://doi.org/10.1016/j.jtcvs.2012.06.045
    • La Meir, M., Gelsomino, S., Luca, F., Pison, L., Rao, C. M., Wellens, F., & Maessen, J. G. (2013). Improvement of left atrial function and left atrial reverse remodeling after minimally invasive radiofrequency ablation evaluated by 2-dimensional speckle tracking echocardiography. Journal of Thoracic and Cardiovascular Surgery, 146(1), 72-77. https://doi.org/10.1016/j.jtcvs.2012.05.068
    • Bosch, Y., Al Dieri, R., Ten Cate, H., Nelemans, P., Bloemen, S., Hemker, C., Weerwind, P., Maessen, J., & Mochtar, B. (2013). Preoperative thrombin generation is predictive for the risk of blood loss after cardiac surgery: a research article. Journal of Cardiothoracic Surgery, 8(1). https://doi.org/10.1186/1749-8090-8-154
    • Verberkmoes, N. J., Mokhles, M. M., Bramer, S., Van Straten, A. H. M., Ter Woorst, J. F., Maessen, J. G., & Berreklouw, E. (2013). Clinical outcome of the PAS-Port (R) proximal anastomosis system in off-pump coronary artery bypass grafting in 201 patients. Journal of Cardiovascular Surgery, 54(3), 389-395.
    • Gelsomino, S., Luca, F., Nediani, C., Orlandini, S. Z., Bani, D., Rubino, A. S., Renzulli, A., Lorusso, R., Consolo, A., Lo Cascio, A., Maessen, J., & Gensini, G. F. (2013). Early Hemodynamic and Biochemical Changes in Overloaded Swine Ventricle. Texas Heart Institute Journal, 40(3), 235-245.
    • van Garsse, L., Gelsomino, S., Luca, F., Parise, O., Cheriex, E., Rao, C. M., Gensini, G. F., & Maessen, J. G. (2013). Left atrial strain and strain rate before and following restrictive annuloplasty for ischaemic mitral regurgitation evaluated by two-dimensional speckle tracking echocardiography. European Heart Journal Cardiovascular Imaging, 14(6), 534-543. https://doi.org/10.1093/ehjci/jes206
    • Gelsomino, S., Corradi, D., Lorusso, R., Parise, O., Callegari, S., Macchi, E., Maessen, J., & La Meir, M. (2013). Anatomical basis of minimally invasive epicardial ablation of atrial fibrillation. European Journal of Cardio-Thoracic Surgery, 43(4), 673-682. https://doi.org/10.1093/ejcts/ezs550
    • Gelsomino, S., van Garsse, L., Luca, F., Parise, O., Cheriex, E., Rao, C. M., Gensini, G. F., & Maessen, J. (2013). Left Ventricular Strain in Chronic Ischemic Mitral Regurgitation in Relation to Mitral Tethering Pattern. Journal of the American Society of Echocardiography, 26(4), 370-380.e11. https://doi.org/10.1016/j.echo.2013.01.011
    • Simons, A. P., Ganushchak, Y. M., Teerenstra, S., Bergmans, D. C., Maessen, J. G., & Weerwind, P. W. (2013). Hypovolemia in Extracorporeal Life Support Can Lead to Arterial Gaseous Microemboli. Artificial Organs, 37(3), 276-282. https://doi.org/10.1111/j.1525-1594.2012.01560.x
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