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MLDS grant Sabine Daemen

MLDS grant Sabine Daemen

15 November 2024

Dr Sabine Daemen (Dept of Internal Medicine) received a Career Development Grant (160k) from the Dutch Digestive Foundation (MLDS).

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Our new Division Leaders

Our new Division Leaders

3 October 2024

As of 1 October 2024, Casper Schalkwijk and Joost Lumens have been appointed as Division Leaders Vessels and Heart. Judith Sluimer will success Hugo ten Cate as Division Leader Blood in March 2025.

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Carim Maastricht
Carim Maastricht

Casper Schalkwijk

Professor

Prof. Casper Schalkwijk studied chemistry at University Utrecht and graduated in biochemistry. At the same university he obtained his PhD in 1992. He did post-graduate training in endothelial cell biology at TNO-PG in Leiden. He was appointed in 1995 as assistant professor and staff member at the Department of Clinical Chemistry at the Vrije Universiteit Medical Cente in Amsterdam and from 2004 as associate professor. He has led the Vascular Unit. He moved to the Department of Internal Medicine at Maastricht University in 2005, where he is heading the Laboratory for Metabolism and Vascular Medicine (~15fte). He was appointed as Professor of Experimental Internal Medicine at the Faculty of Health, Medicine and Life Sciences (FHML) of Maastricht UMC+ in 2011.

His main research themes are obesity, insulin resistance, endothelial function and vascular complications. The importance of endothelial dysfunction for the development of diabetic complications is studied in epidemiological setting with the availability of several cohorts and with experimental ex-vivo -, animal - and cell work. He has led several clinical studies. A major aim of his programme is to deliver specific and sensitive diagnostic biomarkers for the identification of patients developing  type 2 diabetes and to identify patients with high risk of vascular complications. Robust analytical techniques for measurements of biomarkers with multi-array technology and with UPLC-MSMS are available. A second aim of his programme is to obtain insight in the pathophysiology of vascular complications in diabetes. His current studies focus mainly on the importance non-enzymatic glycation for the development of diabetes and diabetic complications. He discovered, as one of the first, the link between AGEs and vascular complications in individuals with and without diabetes. He is an (inter)nationally recognised expert in the field of glycation. His lab is one of the most renowned labs in this field.The work has been supported by several grants and is now granted by the Diabetes Fonds Nederland, EFSD, NWO, ZonMw and NVWA.

Casper-schalkwijk

Department of Internal Medicine
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: 5.324
T: +31(0)43 388 21 86

  • 2021
    • Zhou, T. L., Kroon, A. A., Henry, R. M. A., Koster, A., Dagnelie, P. C., Bosma, H., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Schalkwijk, C. G., Wesselius, A., Reesink, K. D., Köhler, S., Schram, M. T., Stehouwer, C. D. A., & van Sloten, T. T. (2021). Exercise SBP response and incident depressive symptoms: The Maastricht Study. Journal of Hypertension, 39(3), 494-502. https://doi.org/10.1097/HJH.0000000000002657
    • Maasen, K., Scheijen, J. L. J. M., Opperhuizen, A., Stehouwer, C. D. A., Van Greevenbroek, M. M., & Schalkwijk, C. G. (2021). Quantification of dicarbonyl compounds in commonly consumed foods and drinks; presentation of a food composition database for dicarbonyls. Food Chemistry, 339, Article 128063. https://doi.org/10.1016/j.foodchem.2020.128063
    • Simons, N., Veeraiah, P., Simons, P. I. H. G., Schaper, N. C., Kooi, M. E., Schrauwen-Hinderling, V. B., Feskens, E. J. M., van der Ploeg, E. M. C., Van den Eynde, M. D. G., Schalkwijk, C. G., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2021). Effects of fructose restriction on liver steatosis (FRUITLESS); a double-blind randomized controlled trial. American Journal of Clinical Nutrition, 113(2), 391-400. https://doi.org/10.1093/ajcn/nqaa332
    • Maasen, K., Hanssen, N. M. J., van der Kallen, C. J. H., Stehouwer, C. D. A., van Greevenbroek, M. M. J., & Schalkwijk, C. G. (2021). Polymorphisms in Glyoxalase I Gene Are Not Associated with Glyoxalase I Expression in Whole Blood or Markers of Methylglyoxal Stress: The CODAM Study. Antioxidants, 10(2), Article 219. https://doi.org/10.3390/antiox10020219
    • Hanssen, N. M. J., Scheijen, J. L. J. M., Houben, A. J. H. M., van de Waarenburg, M., Berendschot, T. T. J. M., Webers, C. A. B., Reesink, K. D., van Greevenbroek, M. M. J., van der Kallen, C., Schaper, N. C., Schram, M. T., Henry, R. M. A., Stehouwer, C. D. A., & Schalkwijk, C. G. (2021). Fasting and post-oral-glucose-load levels of methylglyoxal are associated with microvascular, but not macrovascular, disease in individuals with and without (pre)diabetes: The Maastricht Study. Diabetes & Metabolism, 47(1), Article 101148. https://doi.org/10.1016/j.diabet.2020.02.002
    • van der Bruggen, M. M., Reesink, K. D., Spronck, P. J. M., Bitsch, N., Hameleers, J., Megens, R. T. A., Schalkwijk, C. G., Delhaas, T., & Spronck, B. (2021). An integrated set-up for ex vivo characterisation of biaxial murine artery biomechanics under pulsatile conditions. Scientific Reports, 11(1), Article 2671. https://doi.org/10.1038/s41598-021-81151-5
    • Demandt, J. A. F., Dubois, L. J., van Kuijk, K., Zat'ovicova, M., Jin, H., Parkkila, S., van der Laan, S. W., Jelenska, L., Mees, B. M. E., Reutelingsperger, C. P. M., Cleutjens, K. B. J. M., van der Kallen, C. J. H., Schalkwijk, C. G., van Greevenbroek, M. M. J., Biessen, E. A. L., Pasterkamp, G., Pastorekova, S., Stehouwer, C. D. A., & Sluimer, J. C. (2021). The hypoxia-sensor carbonic anhydrase IX affects macrophage metabolism, but is not a suitable biomarker for human cardiovascular disease. Scientific Reports, 11(1), Article 425. https://doi.org/10.1038/s41598-020-79978-5
    • Maalmi, H., Wouters, K., Savelberg, H. H. C. M., van der Velde, J. H. P. M., Reulen, J. P. H., Mess, W., Schalkwijk, C. G., Stehouwer, C. D. A., Roden, M., Ziegler, D., Herder, C., & Schaper, N. C. (2021). Associations of cells from both innate and adaptive immunity with lower nerve conduction velocity: the Maastricht Study. BMJ Open Diabetes Research & Care, 9(1), Article 001698. https://doi.org/10.1136/bmjdrc-2020-001698
    • Aglago, E. K., Rinaldi, S., Freisling, H., Jiao, L., Hughes, D. J., Fedirko, V., Schalkwijk, C. G., Weiderpass, E., Dahm, C. C., Overvad, K., Eriksen, A. K., Kyro, C., Boutron-Ruault, M. C., Rothwell, J. A., Severi, G., Katzke, V., Kuhn, T., Schulze, M. B., Aleksandrova, K., ... Jenab, M. (2021). Soluble Receptor for Advanced Glycation End-products (sRAGE) and Colorectal Cancer Risk: A Case-Control Study Nested within a European Prospective Cohort. Cancer Epidemiology Biomarkers & Prevention, 30(1), 182-192. https://doi.org/10.1158/1055-9965.epi-20-0855
    • Hanssen, N. M. J., Teraa, M., Scheijen, J. L. J. M., Van de Waarenburg, M., Gremmels, H., Stehouwer, C. D. A., Verhaar, M. C., & Schalkwijk, C. G. (2021). Plasma Methylglyoxal Levels Are Associated With Amputations and Mortality in Severe Limb Ischemia Patients With and Without Diabetes. Diabetes Care, 44(1), 157-163. https://doi.org/10.2337/dc20-0581
    • Xin, Y., Hertle, E., van der Kallen, C. J. H., Vogelzangs, N., Arts, I. C. W., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2021). C3 and alternative pathway components are associated with an adverse lipoprotein subclass profile: The CODAM study. Journal of Clinical Lipidology, 15(2), 311-319. https://doi.org/10.1016/j.jacl.2021.01.011
  • 2020
    • Atzeni, I. M., Boersema, J., Pas, H. H., Diercks, G. F. H., Scheijen, J. L. J. M., Schalkwijk, C. G., Mulder, D. J., van der Zee, P., & Smit, A. J. (2020). Is skin autofluorescence (SAF) representative of dermal advanced glycation endproducts (AGEs) in dark skin? A pilot study. Heliyon, 6(11), Article 05364. https://doi.org/10.1016/j.heliyon.2020.e05364
    • Geraets, A. F. J., Kohler, S., Muzambi, R., Schalkwijk, C. G., Oenema, A., Eussen, S. J. P. M., Dagnelie, P. C., Stehouwer, C. D. A., Schaper, N. C., Henry, R. M. A., van der Kallen, C. J. H., Wesselius, A., Koster, A., Verhey, F. R. J., & Schram, M. T. (2020). The association of hyperglycaemia and insulin resistance with incident depressive symptoms over 4 years of follow-up: The Maastricht Study. Diabetologia, 63(11), 2315-2328. https://doi.org/10.1007/s00125-020-05247-9
    • Buziau, A. M., Scheijen, J. L. J. M., Stehouwer, C. D. A., Simons, N., Brouwers, M. C. G. J., & Schalkwijk, C. G. (2020). Development and validation of a UPLC-MS/MS method to quantify fructose in serum and urine. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1155, Article 122299. https://doi.org/10.1016/j.jchromb.2020.122299
    • Martens, R. J. H., Broers, N. J. H., Canaud, B., Christiaans, M. H. L., Cornelis, T., Gauly, A., Hermans, M. M. H., Konings, C. J. A. M., van der Sande, F. M., Scheijen, J. L. J. M., Stifft, F., Kooman, J. P., & Schalkwijk, C. G. (2020). Advanced glycation endproducts and dicarbonyls in end-stage renal disease: associations with uraemia and courses following renal replacement therapy. Clinical Kidney Journal, 13(5), 855-866. https://doi.org/10.1093/ckj/sfz099
    • Cordova, R., Knaze, Viallon, V., Rust, P., Schalkwijk, C. G., Weiderpass, E., Wagner, K.-H., Mayen-Chacon, A.-L., Aglago, E. K., Dahm, C. C., Overvad, K., Tjonneland, A., Halkjaer, J., Mancini, F. R., Boutron-Ruault, M.-C., Fagherazzi, G., Katzke, Kuehn, T., Schulze, M. B., ... Freisling, H. (2020). Dietary intake of advanced glycation end products (AGEs) and changes in body weight in European adults. European Journal of Nutrition, 59(7), 2893-2904. https://doi.org/10.1007/s00394-019-02129-8
    • Joris, P. J., Plat, J., Kusters, Y. H. A. M., Houben, A. J. H. M., Stehouwer, C. D. A., Schalkwijk, C. G., & Mensink, R. P. (2020). Effects of diet-induced weight loss on postprandial vascular function after consumption of a mixed meal: Results of a randomized controlled trial with abdominally obese men. Clinical Nutrition, 39(10), 2998-3004. https://doi.org/10.1016/j.clnu.2020.01.006
    • Wouters, K., Kusters, Y. H. A. M., Bijnen, M., Wetzels, S., Zhang, X., Linssen, P. B. C., Gaens, K., Houben, A. J. H. M., Joris, P. J., Plat, J., Kooi, M. E., van der Kallen, C. J. H., Mensink, R. P., Verboven, K., Jocken, J., Hansen, D., Blaak, E. E., Ehlers, F. A. I., Wieten, L., ... Schalkwijk, C. G. (2020). NK cells in human visceral adipose tissue contribute to obesity-associated insulin resistance through low-grade inflammation. Clinical and Translational Medicine, 10(6), Article e192. https://doi.org/10.1002/ctm2.192
    • Hanssen, N. M. J., Kraakman, M. J., Flynn, M. C., Nagareddy, P. R., Schalkwijk, C. G., & Murphy, A. J. (2020). Postprandial Glucose Spikes, an Important Contributor to Cardiovascular Disease in Diabetes?Frontiers in Cardiovascular Medicine, 7, Article 570553. https://doi.org/10.3389/fcvm.2020.570553
    • Hammerschlag, A. R., Byrne, E. M., Bartels, M., Wray, N. R., Middeldorp, C. M., eQTLgen Consortium, Stehouwer, C., BIOS Consortium, Isaacs, A., van der Kallen, C., & Schalkwijk, C. (2020). Refining Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder Genetic Loci by Integrating Summary Data From Genome-wide Association, Gene Expression, and DNA Methylation Studies. Biological Psychiatry, 88(6), 470-479. https://doi.org/10.1016/j.biopsych.2020.05.002
    • Flynn, M. C., Kraakman, M. J., Tikellis, C., Lee, M. K. S., Hanssen, N. M. J., Kammoun, H. L., Pickering, R. J., Dragoljevic, D., Al-Sharea, A., Barrett, T. J., Hortle, F., Byrne, F. L., Olzomer, E., McCarthy, D. A., Schalkwijk, C. G., Forbes, J. M., Hoehn, K., Makowski, L., Lancaster, G. I., ... Murphy, A. J. (2020). Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis. Circulation Research, 127(7), 877-892. https://doi.org/10.1161/CIRCRESAHA.120.316653
    • Li, W., Schram, M. T., Sörensen, B. M., van Agtmaal, M. J. M., Berendschot, T. T. J. M., Webers, C. A. B., Jansen, J. F. A., Backes, W. H., Gronenschild, E. H. B. M., Schalkwijk, C. G., Stehouwer, C. D. A., & Houben, A. J. H. M. (2020). Microvascular Phenotyping in the Maastricht Study: Design and Main Findings, 2010-2018. American Journal of Epidemiology, 189(9), 873-884. https://doi.org/10.1093/aje/kwaa023
    • Zhou, T. L., Rensma, S. P., van der Heide, F. C. T., Henry, R. M. A., Kroon, A. A., Houben, A. J. H. M., Jansen, J. F. A., Backes, W. H., Berendschot, T. T. J. M., Schouten, J. S. A. G., van Dongen, M. C. J. M., Eussen, S. J. P. M., Dagnelie, P. C., Webers, C. A. B., Schram, M. T., Schalkwijk, C. G., van Sloten, T. T., & Stehouwer, C. D. A. (2020). Blood pressure variability and microvascular dysfunction: the Maastricht Study. Journal of Hypertension, 38(8), 1541-1550. https://doi.org/10.1097/HJH.0000000000002444
    • van der Velde, J. H. P. M., Koster, A., Strotmeyer, E. S., Mess, W. H., Hilkman, D., Reulen, J. P. H., Stehouwer, C. D. A., Henry, R. M. A., Schram, M. T., van der Kallen, C. J. H., Schalkwijk, C. G., Savelberg, H. H. C. M., & Schaper, N. C. (2020). Cardiometabolic risk factors as determinants of peripheral nerve function: the Maastricht Study. Diabetologia, 63(8), 1648-1658. https://doi.org/10.1007/s00125-020-05194-5
    • Zwakenberg, S. R., de Jong, P. A., Hendriks, E. J., Westerink, J., Spiering, W., de Borst, G. J., Cramer, M. J., Bartstra, J. W., Doesburg, T., Rutters, F., van der Heijden, A. A., Schalkwijk, C., Schurgers, L. J., van der Schouw, Y. T., Beulens, J. W. J., & SMART Study Grp (2020). Intimal and medial calcification in relation to cardiovascular risk factors. PLOS ONE, 15(7), Article 0235228. https://doi.org/10.1371/journal.pone.0235228
    • Linssen, P. B. C., Brunner-La Rocca, H.-P., Schalkwijk, C. G., Beulens, J. W. J., Elders, P. J. M., Van der Heijden, A. A., Slieker, R. C., Stehouwer, C. D. A., & Henry, R. M. A. (2020). Serum Matrix Metalloproteinases and Left Atrial Remodeling-The Hoorn Study. International journal of molecular sciences, 21(14), Article 4944. https://doi.org/10.3390/ijms21144944
    • Rensma, S. P., Stehouwer, C. D. A., Van Boxtel, M. P. J., Houben, A. J. H. M., Berendschot, T. T. J. M., Jansen, J. F. A., Schalkwijk, C. G., Verhey, F. R. J., Kroon, A. A., Henry, R. M. A., Backes, W. H., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Bosma, H., Köhler, S., Reesink, K. D., Schram, M. T., & van Sloten, T. T. (2020). Associations of Arterial Stiffness With Cognitive Performance, and the Role of Microvascular Dysfunction: The Maastricht Study. Hypertension, 75(6), 1607-1614. https://doi.org/10.1161/hypertensionaha.119.14307
    • Simons, N., Debray, F.-G., Schaper, N. C., Feskens, E. J. M., Hollak, C. E. M., Bons, J. A. P., Bierau, J., Houben, A. J. H. M., Schalkwijk, C. G., Stehouwer, C. D. A., Cassiman, D., & Brouwers, M. C. G. J. (2020). Kidney and vascular function in adult patients with hereditary fructose intolerance. Molecular Genetics and Metabolism Reports, 23, Article 100600. https://doi.org/10.1016/j.ymgmr.2020.100600
    • Xin, Y., Hertle, E., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2020). Associations of dicarbonyl stress with complement activation: the CODAM study. Diabetologia, 63(5), 1032-1042. https://doi.org/10.1007/s00125-020-05098-4
    • Van den Eynde, M. D. G., Streese, L., Houben, A. J. H. M., Stehouwer, C. D. A., Scheijen, J. L. J. M., Schalkwijk, C. G., Hanssen, N. M. J., & Hanssen, H. (2020). Physical activity and markers of glycation in older individuals: data from a combined cross-sectional and randomized controlled trial (EXAMIN AGE). Clinical Science, 134(9), 1095-1105. https://doi.org/10.1042/CS20200255
    • Buziau, A. M., Schalkwijk, C. G., Stehouwer, C. D. A., Tolan, D. R., & Brouwers, M. C. G. J. (2020). Recent advances in the pathogenesis of hereditary fructose intolerance: implications for its treatment and the understanding of fructose-induced non-alcoholic fatty liver disease. Cellular and Molecular Life Sciences, 77(9), 1709-1719. https://doi.org/10.1007/s00018-019-03348-2
    • Simons, N., Bijnen, M., Wouters, K. A. M., Rensen, S. S., Beulens, J. W. J., van Greevenbroek, M. M. J., 't Hart, L. M., Greve, J. W. M., van der Kallen, C. J. H., Schaper, N. C., Schalkwijk, C. G., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2020). The endothelial function biomarker soluble E-selectin is associated with nonalcoholic fatty liver disease. Liver International, 40(5), 1079-1088. https://doi.org/10.1111/liv.14384
    • Zhang, C., Couppe, C., Scheijen, J. L. J. M., Schalkwijk, C. G., Kjaer, M., Magnusson, S. P., & Svensson, R. B. (2020). Regional collagen turnover and composition of the human patellar tendon. Journal of Applied Physiology, 128(4), 884-891. https://doi.org/10.1152/japplphysiol.00030.2020
    • Schutten, M. T. J., Kusters, Y. H. A. M., Houben, A. J. H. M., Niessen, H. E., Roodt, J. O., Scheijen, J. L. J. M., van de Waardenburg, M. P., Schalkwijk, C. G., de Leeuw, P. W., & Stehouwer, C. D. A. (2020). Glucocorticoids affect metabolic but not muscle microvascular insulin sensitivity following high versus low salt intake. JCI INSIGHT, 5(6), Article 127530. https://doi.org/10.1172/jci.insight.127530
    • Bellier, J., Nokin, M. J., Caprasse, M., Tiamiou, A., Blomme, A., Scheijen, J. L., Koopmansch, B., MacKay, G. M., Chiavarina, B., Costanza, B., Rademaker, G., Durieux, F., Agirman, F., Maloujahmoum, N., Cusumano, P. G., Lovinfosse, P., Leung, H. Y., Lambert, F., Bours, V., ... Bellahcene, A. (2020). Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab. Cell Reports, 30(5), 1400-1416.e6. https://doi.org/10.1016/j.celrep.2020.01.012
    • Ouwens, K. G., Jansen, R., Nivard, M. G., van Dongen, J., Frieser, M. J., Hottenga, J.-J., Arindrarto, W., Claringbould, A., van Iterson, M., Mei, H., Franke, L., Heijmans, B. T., 't Hoen, P. A. C., van Meurs, J., Brooks, A., Penninx, B. W. J. H., Boomsma, D., Isaacs, A., Pool, R., ... BIOS Consortium (2020). A characterization of cis- and trans-heritability of RNA-Seq-based gene expression. European Journal of Human Genetics, 28(2), 253-263. https://doi.org/10.1038/s41431-019-0511-5
    • Schalkwijk, C. G., & Stehouwer, C. D. A. (2020). METHYLGLYOXAL, A HIGHLY REACTIVE DICARBONYL COMPOUND, IN DIABETES, ITS VASCULAR COMPLICATIONS, AND OTHER AGE-RELATED DISEASES. Physiological Reviews, 100(1), 407-461. https://doi.org/10.1152/physrev.00001.2019
    • Rensma, S. P., van Sloten, T. T., Houben, A. J. H. M., Koehler, S., van Boxtel, M. P. J., Berendschot, T. T. J. M., Jansen, J. F. A., Verhey, F. R. J., Kroon, A. A., Koster, A., Backes, W. H., Schaper, N., Dinant, G.-J., Schalkwijk, C. G., Henry, R. M. A., Wolfs, E. M. L., van Heumen, M. J. A., Schram, M. T., & Stehouwer, C. D. A. (2020). Microvascular Dysfunction Is Associated With Worse Cognitive Performance The Maastricht Study. Hypertension, 75(1), 237-245. https://doi.org/10.1161/hypertensionaha.119.13023
    • Wetzels - van Hooijdonk, S., Bijnen, M., Wijnands, E., van de Gaar, M. J., Tan, A., Coort, S., Biessen, E., Schalkwijk, C., & Wouters, K. (2020). CD11c−MHC2low Macrophages Are a New Inflammatory and Dynamic Subset in Murine Adipose Tissue. Immunometabolism, 2(2), Article e200015. https://doi.org/10.20900/immunometab20200015
    • Josefs, T., Wouters, K., Tietge, U. J. F., Annema, W., Dullaart, R. P. F., Vaisar, T., Arts, I. C. W., van der Kallen, C. J. H., Stehouwer, C. D. A., Schalkwijk, C. G., Goldberg, I. J., Fisher, E. A., & van Greevenbroek, M. M. J. (2020). High-density lipoprotein cholesterol efflux capacity is not associated with atherosclerosis and prevalence of cardiovascular outcome: The CODAM study. Journal of Clinical Lipidology, 14(1), 122-132.e4. https://doi.org/10.1016/j.jacl.2019.10.012
  • 2019
    • van der Kolk, B. W., Kalafati, M., Adriaens, M., van Greevenbroek, M. M. J., Vogelzangs, N., Saris, W. H. M., Astrup, A., Valsesia, A., Langin, D., van der Kallen, C. J. H., Eussen, S. J. P. M., Schalkwijk, C. G., Stehouwer, C. D. A., Goossens, G. H., Arts, I. C. W., Jocken, J. W. E., Evelo, C. T., & Blaak, E. E. (2019). Subcutaneous Adipose Tissue and Systemic Inflammation Are Associated With Peripheral but Not Hepatic Insulin Resistance in Humans. Diabetes, 68(12), 2247-2258. https://doi.org/10.2337/db19-0560
    • Simons, N., Debray, F.-G., Schaper, N. C., Kooi, M. E., Feskens, E. J. M., Hollak, C. E. M., Lindeboom, L., Koek, G. H., Bons, J. A. P., Lefeber, D. J., Hodson, L., Schalkwijk, C. G., Stehouwer, C. D. A., Cassiman, D., & Brouwers, M. C. G. J. (2019). Patients With Aldolase B Deficiency Are Characterized by Increased Intrahepatic Triglyceride Content. Journal of Clinical Endocrinology & Metabolism, 104(11), 5056-5064. https://doi.org/10.1210/jc.2018-02795
    • van Dongen, J., Zilhao, N. R., Sugden, K., Hannon, E. J., Mill, J., Caspi, A., Agnew-Blais, J., Arseneault, L., Corcoran, D. L., Moffitt, T. E., Poulton, R., Franke, B., Boomsma, D., Heijmans, B. T., t'Hoen, P. A. G., van Meurs, J., Isaacs, A., Jansen, R., Franke, L., ... BIOS Consortium (2019). Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults. Biological Psychiatry, 86(8), 599-607. https://doi.org/10.1016/j.biopsych.2019.02.016
    • Sotomayor, C. G., Gomes-Neto, A. W., van Londen, M., Gans, R. O. B., Nolte, I. M., Berger, S. P., Navis, G. J., Rodrigo, R., Leuvenink, H. G. D., Schalkwijk, C. G., & Bakker, S. J. L. (2019). Circulating Advanced Glycation Endproducts and Long-Term Risk of Cardiovascular Mortality in Kidney Transplant Recipients. Clinical journal of the American Society of Nephrology, 14(10), 1512-1520. https://doi.org/10.2215/CJN.00540119
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    • van Der Plaat, D., Vonk, J. M., Terzikhan, N., de Jong, K., de Vries, M., La Bastide-van Gemert, S., van Diemen, C. C., Lahousse, L., Brusselle, G., Nedeljkovic, I., Amin, N., Kromhout, H., Vermeulen, R. C. H., Postma, D. S., van Duijn, C. M., Boezen, H. M., Heijmans, B. T., Hoen, P. A. C. T., van Meurs, J., ... BIOS Consortium (2019). Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression. Human Molecular Genetics, 28(15), 2477-2485. https://doi.org/10.1093/hmg/ddz067
    • Mandaviya, P. R., Joehanes, R., Brody, J., Castillo-Fernandez, J. E., Dekkers, K. F., Do, A. N., Graff, M., Hänninen, I. K., Tanaka, T., de Jonge, E. A. L., Kiefte-de Jong, J. C., Absher, D. M., Aslibekyan, S., de Rijke, Y. B., Fornage, M., Hernandez, D. G., Hurme, M. A., Ikram, M. A., Jacques, P. F., ... BIOS Consortium, CHARGE Consortium Epigenetics Working Group, CHARGE Consortium Nutrition Working Group (2019). Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals. American Journal of Clinical Nutrition, 110(2), 437-450. Article 15. https://doi.org/10.1093/ajcn/nqz031
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