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MLDS grant Sabine Daemen

MLDS grant Sabine Daemen

15 November 2024

Dr Sabine Daemen (Dept of Internal Medicine) received a Career Development Grant (160k) from the Dutch Digestive Foundation (MLDS).

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Our new Division Leaders

Our new Division Leaders

3 October 2024

As of 1 October 2024, Casper Schalkwijk and Joost Lumens have been appointed as Division Leaders Vessels and Heart. Judith Sluimer will success Hugo ten Cate as Division Leader Blood in March 2025.

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Carim Maastricht
Carim Maastricht

Miranda Schram

Professor

Dr Miranda Schram holds a MSc in Biomedical Sciences (1999) and in Epidemiology (2002). She recieved her PhD entitled 'Patophysiology of diabetic complications, arterial stiffness, endothelial dysfunction and inflammation' at VU University Medical Center in Amsterdam in 2004, and is a registered Epidemiologist B. She has worked as post-doc epidemiologist at Erasmus MC in Rotterdam, at Leiden University Medical Center and as senior investigator at the National Institute for Public Health and the Environment in Bilthoven. From 2008 onwards, she has been working at Maastricht UMC+ as senior investigator at The Maastricht Study.

Miranda Schram is one of the founders of The Maastricht Study, a novel population-based cohort study on type 2 diabetes and its complications. Her scientific work focusses on the etiology and epidemiology of cognitive decline and depression in type 2 diabetes with a specific interest in the role of early vascular dysfunction. A second research line focusses on psychosocial aspects of diabetes, to understand how social networks, but also ethnicity and diabetes distress can affect diabetes treatment and the development of complications. Miranda is board member of The Maastricht Study, coordinator of the Dutch Diabetes Pearlstring Initiative, active member of the PSAD study group of the EASD and involved in the Netherlands Consortium of Demetia Cohorts.

Miranda-schram

Department of Internal Medicine
Randwycksingel 35, 6229 EG Maastricht
T: +31(0)6 122 64 289

  • 2014
    • van Sloten, T. T., Henry, R. M. A., Dekker, J. M., Nijpels, G., Unger, T., Schram, M. T., & Stehouwer, C. D. A. (2014). Endothelial Dysfunction Plays a Key Role in Increasing Cardiovascular Risk in Type 2 Diabetes The Hoorn Study. Hypertension, 64(6), 1299-U293. https://doi.org/10.1161/HYPERTENSIONAHA.114.04221
    • Muris, D. M. J., Gronenschild, E. H. B. M., Schram, M. T., Karaca, U., Stehouwer, C. D. A., & Houben, A. J. H. M. (2014). Response to comment on: Semi-automatic assessment of skin capillary density: Proof of principle and validation. Microvascular Research, 94, 7-8. https://doi.org/10.1016/j.mvr.2014.04.006
    • van Sloten, T. T., Schram, M. T., van den Hurk, K., Dekker, J. M., Nijpels, G., Henry, R. M. A., & Stehouwer, C. D. A. (2014). Local Stiffness of the Carotid and Femoral Artery Is Associated With Incident Cardiovascular Events and All-Cause Mortality The Hoorn Study. Journal of the American College of Cardiology, 63(17), 1739-1747. https://doi.org/10.1016/j.jacc.2013.12.041
    • van Sloten, T. T., Schram, M. T., Adriaanse, M. C., Dekker, J. M., Nijpels, G., Teerlink, T., Scheffer, P. G., Pouwer, F., Schalkwijk, C. G., Stehouwer, C. D. A., & Henry, R. M. A. (2014). Endothelial dysfunction is associated with a greater depressive symptom score in a general elderly population: the Hoorn Study. Psychological Medicine, 44(7), 1403-1416. https://doi.org/10.1017/S0033291713002043
    • Schram, M. T., Sep, S. J. S., van der Kallen, C. J., Dagnelie, P. C., Koster, A., Schaper, N., Henry, R. M. A., & Stehouwer, C. D. A. (2014). The Maastricht Study: an extensive phenotyping study on determinants of type 2 diabetes, its complications and its comorbidities. European Journal of Epidemiology, 29(6), 439-451. https://doi.org/10.1007/s10654-014-9889-0
    • Karaca, U., Schram, M. T., Houben, A. J. H. M., Muris, D. M. J., & Stehouwer, C. D. A. (2014). Microvascular dysfunction as a link between obesity, insulin resistance and hypertension. Diabetes Research and Clinical Practice, 103(3), 382-387. https://doi.org/10.1016/j.diabres.2013.12.012
  • 2013
    • Gronenschild, E. H. B. M., Muris, D. M. J., Schram, M. T., Karaca, U., Stehouwer, C. D. A., & Houben, A. J. H. M. (2013). Semi-automatic assessment of skin capillary density: Proof of principle and validation. Microvascular Research, 90, 192-198. https://doi.org/10.1016/j.mvr.2013.08.003
    • van Eupen, M. G. A., Schram, M. T., Colhoun, H. M., Scheijen, J. L. J. M., Stehouwer, C. D. A., & Schalkwijk, C. G. (2013). Plasma levels of advanced glycation endproducts are associated with type 1 diabetes and coronary artery calcification. Cardiovascular Diabetology, 12(1), Article 149. https://doi.org/10.1186/1475-2840-12-149
    • van Eupen, M. G. A., Schram, M. T., Colhoun, H. M., Hanssen, N. M. J., Niessen, H. W. M., Tarnow, L., Parving, H. H., Rossing, P., Stehouwer, C. D. A., & Schalkwijk, C. G. (2013). The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1. Diabetologia, 56(8), 1845-1855. https://doi.org/10.1007/s00125-013-2919-8
    • van Dooren, F. E. P., Nefs, G., Schram, M. T., Verhey, F. R. J., Denollet, J., & Pouwer, F. (2013). Depression and Risk of Mortality in People with Diabetes Mellitus: A Systematic Review and Meta-Analysis. PLOS ONE, 8(3), Article e57058. https://doi.org/10.1371/journal.pone.0057058
    • Muris, D. M. J., Houben, A. J., Schram, M. T., & Stehouwer, C. D. A. (2013). Microvascular dysfunction: An emerging pathway in the pathogenesis of obesity-related insulin resistance.Reviews in Endocrine & Metabolic Disorders, 14(1), 29-38. https://doi.org/10.1007/s11154-012-9231-7
    • Pouwer, F., Wijnhoven, H. A. H., Ujcic-Voortman, J. K., de Wit, M., Schram, M. T., Baan, C. A., & Snoek, F. J. (2013). Ethnic aspects of emotional distress in patients with diabetes - the Amsterdam Health Monitor Study. Diabetic Medicine, 30(1), E25-E31. https://doi.org/10.1111/dme.12031
  • 2012
    • Muris, D. M. J., Houben, A. J. H. M., Schram, M. T., & Stehouwer, C. D. A. (2012). Microvascular Dysfunction Is Associated With a Higher Incidence of Type 2 Diabetes Mellitus A Systematic Review and Meta-Analysis. Arteriosclerosis Thrombosis and Vascular Biology, 32(12), 3082-3094. https://doi.org/10.1161/ATVBAHA.112.300291
    • Van't Riet, E., Schram, M. T., Abbink, E. J., Admiraal, W. M., Dijk-Schaap, M. W., Holleman, F., Nijpels, G., Ozcan, B., Pijl, H., Schaper, N. C., Sijbrands, E. J. G., Silvius, B., Tack, C. J., de Valk, H. W., Wolffenbuttel, B. H. R., Stehouwer, C. D. A., & Dekker, J. M. (2012). The Diabetes Pearl: Diabetes biobanking in The Netherlands. BMC Public Health, 12(1), 949. https://doi.org/10.1186/1471-2458-12-949
  • 2007
    • Schram, M. T., Euser, S. M., Craen, A. J., Witteman, J. C. M., Frolich, M., Hofman, A., Jolles, J., Breteler, M. M., & Westendorp, R. G. J. (2007). Systemic markers of inflammation and cognitive decline in old age. Journal of the American Geriatrics Society, 55 (5), 708-16. https://doi.org/10.1111/j.1532-5415.2007.01159.x
  • 2006
    • Schalkwijk, C. G., Chaturverdi, N., Schram, M. T., Fuller, J. H., & Stehouwer, C. D. A. (2006). Re: Adiponectin and renal function: pitfalls of renal function estimates and corrections for BSA. Journal of Clinical Endocrinology & Metabolism.
  • 2005
    • Schram, M. T., Schalkwijk, C. G., Bootsma, A. H., Fuller, J. H., Chaturvedi, N., & Stehouwer, C. D. (2005). Advanced glycation end products are associated with pulse pressure in type 1 diabetes: the EURODIAB Prospective Complications Study. Hypertension, 46(1), 232-237. https://doi.org/10.1161/01.HYP.0000164574.60279.ba
    • Schram, M. T., van Ittersum, F. J., Spoelstra-de Man, A. M., van Dijk, R. A. J. M., Schalkwijk, C. G., Ijzerman, R. G., Twisk, J. W. R., & Stehouwer, C. D. A. (2005). Aggressive antihypertensive therapy based on hydrochlorothiazide candesartan or lisinopril as initial choice in hypertensive type II diabetic individuals effects on albumin excretion endothelial function and inflammation in a double-blind randomized cl. Journal of Human Hypertension, 19, 429-437. https://doi.org/10.1038/sj.jhh.1001812
    • Schram, M. T., & Stehouwer, C. D. (2005). Endothelial dysfunction, cellular adhesion molecules and the metabolic syndrome. Hormone and Metabolic Research, 37 Suppl 1, 49-55. https://doi.org/10.1055/s-2005-861363
    • Schram, M. T., Chaturvedi, N., Schalkwijk, C. G., Fuller, J. H., Stehouwer, C. D. A., & EURODIAB ProspectivE Compl.St., G. (2005). Markers of inflammation are cross-sectionally associated with microvascular complications and cardiovascular disease in type 1 diabetes--the EURODIAB Prospective Complications Study. Diabetologia, 48(2), 370-378. https://doi.org/10.1007/s00125-004-1628-8
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