• 2019
    • Driessen, J. H. M., de Vries, F., van Onzenoort, H. A. W., Schram, M. T., van der Kallen, C., Reesink, K. D., Sep, S., Stehouwer, C. D. A., Schaper, N., Kroon, A. A., Schalkwijk, C., van den Bergh, J. P. W., & Henry, R. M. A. (2019). Metformin use in type 2 diabetic patients is not associated with lower arterial stiffness: the Maastricht Study. Journal of Hypertension, 37(2), 365-371. https://doi.org/10.1097/HJH.0000000000001892
    • Nokin, M.-J., Bellier, J., Durieux, F., Peulen, O., Rademaker, G., Gabriel, M., Monseur, C., Charloteaux, B., Verbeke, L., van Laere, S., Roncarati, P., Herfs, M., Lambert, C., Scheijen, J., Schalkwijk, C., Colige, A., Caers, J., Delvenne, P., Turtoi, A., ... Bellahcene, A. (2019). Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer. Breast Cancer Research, 21(1), Article 11. https://doi.org/10.1186/s13058-018-1095-7
    • Cobussen, M., Stassen, P. M., Posthouwer, D., van Tiel, F. H., Savelkoul, P. H. M., Havenith, T., & Haeseker, M. B. (2019). Improving peak concentrations of a single dose regime of gentamicin in patients with sepsis in the emergency department. PLOS ONE, 14(1), Article 0210012. https://doi.org/10.1371/journal.pone.0210012
    • Zelis, N., Mauritz, A. N., Kuijpers, L. I. J., Buijs, J., de Leeuw, P. W., & Stassen, P. M. (2019). Short-term mortality in older medical emergency patients can be predicted using clinical intuition: A prospective study. PLOS ONE, 14(1), Article 0208741. https://doi.org/10.1371/journal.pone.0208741
    • Nielen, J. T. H., de Vries, F., van der Velde, J. H. P. M., Savelberg, H. H. C. M., Schaper, N. C., Dagnelie, P. C., Henry, R. M. A., Schram, M., Stehouwer, C. D. A., Boonen, A., Koster, A., & van den Bemt, B. J. F. (2019). The Association Between β-Blocker Use and Cardiorespiratory Fitness: The Maastricht Study. Journal of Cardiovascular Pharmacology and Therapeutics, 24(1), 37-45. https://doi.org/10.1177/1074248418778551
    • Luijten, J., van Greevenbroek, M. M. J., Schaper, N. C., Meex, S. J. R., van der Steen, C., Meijer, L. J., de Boer, D., de Graaf, J., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2019). Incidence of cardiovascular disease in familial combined hyperlipidemia: A 15-year follow-up study. Atherosclerosis, 280, 1-6. https://doi.org/10.1016/j.atherosclerosis.2018.11.013
    • Denissen, K. F. M., Heil, S. G., Eussen, S. J. P. M., Heeskens, J. P. J., Thijs, C., Mommers, M., Smits, L. J. M., van Dongen, M. C. J. M., & Dagnelie, P. C. (2019). Intakes of Vitamin B-12 from Dairy Food, Meat, and Fish and Shellfish Are Independently and Positively Associated with Vitamin B-12 Biomarker Status in Pregnant Dutch Women. Journal of Nutrition, 149(1), 131-138. https://doi.org/10.1093/jn/nxy233
    • Hanssen, N. M. J., Stehouwer, C. D. A., & Schalkwijk, C. G. (2019). Methylglyoxal stress, the glyoxalase system, and diabetic chronic kidney disease. Current Opinion in Nephrology and Hypertension, 28(1), 26-33. https://doi.org/10.1097/MNH.0000000000000465
    • van Twist, D. J. L., de Leeuw, P. W., Spiering, W., Rossi, G. P., Dominiczak, A. F., Jennings, G. L. R., Barigou, M., Persu, A., & Kroon, A. A. (2019). Unifocal and Multifocal Fibromuscular Dysplasia: Two Different Disease Entities in a Single Patient?Hypertension, 73(1), 7-12. https://doi.org/10.1161/HYPERTENSIONAHA.118.12004
    • Schols, A. M. R., Willemsen, R. T. A., Bonten, T. N., Rutten, M. H., Stassen, P. M., Kietselaer, B. L. J. H., Dinant, G.-J., & Cals, J. W. L. (2019). A Nationwide Flash-Mob Study for Suspected Acute Coronary Syndrome. Annals of Family Medicine, 17(4), 296-303. https://doi.org/10.1370/afm.2401
    • Tsioufis, C., de Leeuw, P., Dimitriadis, K., Kasiakogias, A., Kroon, A., Lombardi, C., & Parati, G. (2019). European Society of Hypertension Scientific Newsletter: Update on Hypertension Management 2017; 18: Nr. 65 Update on Device Therapies for resistant hypertension Device-Therapie bei therapieresistenter Hypertonie - Update. Journal fur Hypertonie, 23(2), 49-52. https://www.kup.at/kup/pdf/14515.pdf
    • Bijnen, M., van Greevenbroek, M. M. J., van Der Kallen, C. J. H., Scheijen, J. L., van de Waarenburg, M. P. H., Stehouwer, C. D. A., Wouters, K., & Schallcwijk, C. G. (2019). Hepatic Fat Content and Liver Enzymes Are Associated with Circulating Free and Protein-Bound Advanced Glycation End Products, Which Are Associated with Low-Grade Inflammation: The CODAM Study. Journal of Diabetes Research, 2019, Article 6289831. https://doi.org/10.1155/2019/6289831
    • Wachelder, J., Stassen, P. M., Fourmanov, R. S., Nickel, C. H., & Haak, H. R. (2019). Higher In-Hospital Mortality in Patients with Nonspecific Complaints Presenting to the Emergency Department. Acute Medicine, 18(4), 232-238. https://doi.org/10.52964/amja.0782
    • Rensma, S., van Sloten, T. T., Houben, A. J. H. M., van Boxtel, M. P. J., Berendschot, T. T. J. M., Jansen, J. F. A., Kroon, A. A., Koster, A., Backes, W. H., Schaper, N., Dinant, G. J., Schalkwijk, C. G., Henry, R. M. A., Wolfs, E. M. L., van Heumen, M. J. A., Schram, M. T., & Stehouwer, C. D. A. (2019). Microvascular Dysfunction Is Associated with Worse Cognitive Performance: The Maastricht Study. Journal of Vascular Research, 56(S1), 94-94.
  • 2018
    • van Dongen, J., Bonder, M. J., Dekkers, K. F., Nivard, M. G., van Iterson, M., Willemsen, G., Beekman, M., van der Spek, A., van Meurs, J. B. J., Franke, L., Heijmans, B. T., van Duijn, C. M., Slagboom, P. E., Boomsma, D. I., ’t Hoen, P. A. C., Isaacs, A., Jansen, R., Pool, R., Hottenga, J. J., ... BIOS Consortium (2018). DNA methylation signatures of educational attainment. npj Science of Learning, 3(1), Article 7. https://doi.org/10.1038/s41539-018-0020-2
    • van Agtmaal, M. J. M., Houben, A. J. H. M., de Wit, V., Henry, R. M. A., Schaper, N. C., Dagnelie, P. C., van der Kallen, C. J., Koster, A., Sep, S. J., Kroon, A. A., Jansen, J. F. A., Hofman, P. A., Backes, W. H., Schram, M. T., & Stehouwer, C. D. A. (2018). Prediabetes Is Associated With Structural Brain Abnormalities: The Maastricht Study. Diabetes Care, 41(12), 2535-2543. https://doi.org/10.2337/dc18-1132
    • de Leeuw, P. W., & Kroon, A. A. (2018). A sluice to normotension?Journal of Hypertension, 36(12), 2314-2315. https://doi.org/10.1097/HJH.0000000000001926
    • Sharif, S., Bots, M. L., Schalkwijk, C., Stehouwer, C. D. A., Visseren, F. L. J., Westerink, J., & SMART Study Grp (2018). Association between bone metabolism regulators and arterial stiffness in type 2 diabetes patients. Nutrition Metabolism and Cardiovascular Diseases, 28(12), 1245-1252. https://doi.org/10.1016/j.numecd.2018.06.004
    • Parmar, P., Lowry, E., Cugliari, G., Suderman, M., Wilson, R., Karhunen, V., Andrew, T., Wiklund, P., Wielscher, M., Guarrera, S., Teumer, A., Lehne, B., Milani, L., de Klein, N., Mishra, P. P., Melton, P. E., Mandaviya, P. R., Kasela, S., Nano, J., ... Sebert, S. (2018). Association of maternal prenatal smoking GFI1-locus and cardiometabolic phenotypes in 18,212 adults. EBioMedicine, 38, 206-216. https://doi.org/10.1016/j.ebiom.2018.10.066
    • 't Hart, L. M., Vogelzangs, N., Mook-Kanamori, D. O., Brahimaj, A., Nano, J., van der Heijden, A. A. W. A., van Dijk, K. W., Slieker, R. C., Steyerberg, E. W., Ikram, M. A., Beekman, M., Boomsma, D. I., van Duijn, C. M., Slagboom, P. E., Stehouwer, C. D. A., Schalkwijk, C. G., Arts, I. C. W., Dekker, J. M., Dehghan, A., ... van Greevenbroek, M. M. J. (2018). Blood Metabolomic Measures Associate With Present and Future Glycemic Control in Type 2 Diabetes. Journal of Clinical Endocrinology & Metabolism, 103(12), 4569-4579. https://doi.org/10.1210/jc.2018-01165
    • Xin, Y., Hertle, E., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2018). Complement C3 and C4, but not their regulators or activated products, are associated with incident metabolic syndrome: the CODAM study. Endocrine, 62(3), 617-627. https://doi.org/10.1007/s12020-018-1712-3
    • Van den Eynde, M. D. G., Geleijnse, J. M., Scheijen, J. L. J. M., Hanssen, N. M. J., Dower, J. I., Afman, L. A., Stehouwer, C. D. A., Hollman, P. C. H., & Schalkwijk, C. G. (2018). Quercetin, but Not Epicatechin, Decreases Plasma Concentrations of Methylglyoxal in Adults in a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial with Pure Flavonoids. Journal of Nutrition, 148(12), 1911-1916. https://doi.org/10.1093/jn/nxy236
    • de Waard, E. A. C., de Jong, J. J. A., Koster, A., Savelberg, H. H. C. M., van Geel, T. A., Houben, A. J. H. M., Schram, M. T., Dagnelie, P. C., van der Kallen, C. J., Sep, S. J. S., Stehouwer, C. D. A., Schaper, N. C., Berendschot, T. T. J. M., Schouten, J. S. A. G., Geusens, P. P. M. M., & van den Bergh, J. P. W. (2018). The association between diabetes status, HbA1c, diabetes duration, microvascular disease, and bone quality of the distal radius and tibia as measured with high-resolution peripheral quantitative computed tomography: The Maastricht Study. Osteoporosis International, 29(12), 2725-2738. https://doi.org/10.1007/s00198-018-4678-3
    • van der Velde, J. H. P. M., Schaper, N. C., Stehouwer, C. D. A., van der Kallen, C. J. H., Sep, S. J. S., Schram, M. T., Henry, R. M. A., Dagnelie, P. C., Eussen, S. J. P. M., van Dongen, M. C. J. M., Savelberg, H. H. C. M., & Koster, A. (2018). Which is more important for cardiometabolic health: sedentary time, higher intensity physical activity or cardiorespiratory fitness? The Maastricht Study. Diabetologia, 61(12), 2561-2569. https://doi.org/10.1007/s00125-018-4719-7
    • van Twist, D. J. L., Dinh, T., Bouwmans, E. M. E., & Kroon, A. A. (2018). Initial orthostatic hypotension among patients with unexplained syncope: An overlooked diagnosis?International Journal of Cardiology, 271, 269-273. https://doi.org/10.1016/j.ijcard.2018.05.043
    • van Sloten, T. T., Tafflet, M., Perier, M.-C., Dugravot, A., Climie, R. E. D., Singh-Manoux, A., & Empana, J.-P. (2018). Association of Change in Cardiovascular Risk Factors With Incident Cardiovascular Events. JAMA-Journal of the American Medical Association, 320(17), 1793-1804. https://doi.org/10.1001/jama.2018.16975
    • van Sloten, T. T., Boutouyrie, P., Lisan, Q., Tafflet, M., Thomas, F., Guibout, C., Climie, R. E., Pannier, B., Sharman, J. E., Laurent, S., Jouven, X., & Empana, J.-P. (2018). Body Silhouette Trajectories Across the Lifespan and Vascular Aging: The Paris Prospective Study 3. Hypertension, 72(5), 1095-1102. https://doi.org/10.1161/HYPERTENSIONAHA.118.11442
    • Gala, T. D. L. H., Herder, C., Rutters, F., Carstensen-Kirberg, M., Huth, C., Stehouwer, C. D. A., Nijpels, G., Schalkwijk, C., Flyvbjerg, A., Franks, P. W., Dekker, J., Meisinger, C., Koenig, W., Roden, M., Rathmann, W., Peters, A., Thorand, B., & IMI DIRECT Consortium (2018). Association of changes in inflammation with variation in glycaemia, insulin resistance and secretion based on the KORA study. Diabetes-metabolism Research and Reviews, 34(8), Article 3063. https://doi.org/10.1002/dmrr.3063
    • Bosma, H., Qi, Y., van Boxtel, M., Kohler, S., Schaper, N., Schram, M., Stehouwer, C., & Koster, A. (2018). Disentangling the higher risks of type 2 diabetes in lower educated people.European Journal of Public Health, 28, 50-51. https://doi.org/10.1093/eurpub/cky213.139
    • Daemen, S., Gemmink, A., Brouwers, B., Meex, R. C. R., Huntjens, P. R., Schaart, G., Moonen-Komips, E., Jorgensen, J., Hoeks, J., Schrauwen, P., & Hesselink, M. K. C. (2018). Distinct lipid droplet characteristics and distribution unmask the apparent contradiction of the athlete's paradox. Molecular Metabolism, 17, 71-81. https://doi.org/10.1016/j.molmet.2018.08.004
    • Mbakwa, C. A., Hermes, G. D. A., Penders, J., Savelkoul, P. H. M., Thijs, C., Dagnelie, P. C., Mommers, M., Zoetendal, E. G., Smidt, H., & Arts, I. C. W. (2018). Gut Microbiota and Body Weight in School-Aged Children: The KOALA Birth Cohort Study. Obesity, 26(11), 1767-1776. https://doi.org/10.1002/oby.22320
    • Liesenborghs, I., De Clerck, E. E. B., Berendschot, T. T. J. M., Goezinne, F., Schram, M. T., Henry, R. M. A., Stehouwer, C. D. A., Webers, C. A. B., & Schouten, J. S. A. G. (2018). Prevalence of optical coherence tomography detected vitreomacular interface disorders: The Maastricht Study. Acta Ophthalmologica, 96(7), 729-736. https://doi.org/10.1111/aos.13671
    • Gemmink, A., Daemen, S., Kuijpers, H. J. H., Schaart, G., Duimel, H., Lopez-Iglesias, C., van Zandvoort, M. A. M. J., Knoops, K., & Hesselink, M. K. C. (2018). Super-resolution microscopy localizes perilipin 5 at lipid droplet-mitochondria interaction sites and at lipid droplets juxtaposing to perilipin 2. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1863(11), 1423-1432. https://doi.org/10.1016/j.bbalip.2018.08.016
    • Alfarano, M., Pastore, D., Fogliano, V., Schalkwijk, C. G., & Oliviero, T. (2018). The Effect of Sulforaphane on Glyoxalase I Expression and Activity in Peripheral Blood Mononuclear Cells. Nutrients, 10(11), Article 1773. https://doi.org/10.3390/nu10111773
    • Simons, P. I. H. G., Simons, N., Stehouwer, C. D. A., Schalkwijk, C. G., Schaper, N. C., & Brouwers, M. C. G. J. (2018). Association of common gene variants in glucokinase regulatory protein with cardiorenal disease: A systematic review and meta-analysis. PLOS ONE, 13(10), Article 0206174. https://doi.org/10.1371/journal.pone.0206174
    • Bijnen, M., Beelen, N., Wetzels, S., van De Gaar, J., Vroomen, M., Wijnands, E., Scheijen, J. L., van de Waarenburg, M. P. H., Gijbels, M. J., Cleutjens, J. P., Biessen, E. A. L., Stehouwer, C. D. A., Schalkwijk, C. G., & Wouters, K. (2018). RAGE deficiency does not affect non-alcoholic steatohepatitis and atherosclerosis in Western type diet-fed Ldlr(-/-) mice. Scientific Reports, 8(1), Article 15256. https://doi.org/10.1038/s41598-018-33661-y
    • Tully, P. J., Turnbull, D. A., Anstey, K. J., Beckett, N., Beiser, A. S., Birns, J., Brickman, A. M., Burns, N. R., Cosh, S., de Leeuw, P. W., Dorstyn, D., Elias, M. F., Jukema, J. W., Kario, K., Kikuya, M., Kroon, A. A., Launer, L. J., Mahajan, R., McGrath, E. R., ... VARIABLE BRAIN Consortium (2018). The association between blood pressure variability (BPV) with dementia and cognitive function: a systematic review and meta-analysis protocol. Systematic Reviews, 7(1), Article 163. https://doi.org/10.1186/s13643-018-0811-9
    • Zhou, T. L., Henry, R. M. A., Stehouwer, C. D. A., van Sloten, T. T., Reesink, K. D., & Kroon, A. A. (2018). Blood Pressure Variability, Arterial Stiffness, and Arterial Remodeling: The Maastricht Study. Hypertension, 72(4), 1002-1010. https://doi.org/10.1161/HYPERTENSIONAHA.118.11325
    • CODAM study, & Maastricht Study (2018). Abdominal subcutaneous adipose tissue gene expression in relation to tissue-specific insulin resistance in human obesity. Diabetologia, 61, S110-S110.
    • Schmieder, R. E., Mahfoud, F., Azizi, M., Pathak, A., Dimitriadis, K., Kroon, A. A., Ott, C., Scalise, F., Mancia, G., Tsioufis, C., & ESH Working Group on Interventional Treatment of Hypertension (2018). European Society of Hypertension position paper on renal denervation 2018. Journal of Hypertension, 36(10), 2042-2048. https://doi.org/10.1097/HJH.0000000000001858
    • Uiterwijk, R., Staals, J., Huijts, M., van Kuijk, S. M. J., de Leeuw, P. W., Kroon, A. A., & van Oostenbrugge, R. J. (2018). Hypertensive organ damage predicts future cognitive performance: A 9-year follow-up study in patients with hypertension. Journal of Clinical Hypertension, 20(10), 1458-1463. https://doi.org/10.1111/jch.13372
    • Luijk, R., Wu, H., Ward-Caviness, C. K., Hannon, E., Carnero-Montoro, E., Min, J. L., Mandaviya, P., Muller-Nurasyid, M., Mei, H., van der Maarel, S. M., Relton, C., Mill, J., Waldenberger, M., Bell, J. T., Jansen, R., Zhernakova, A., Franke, L., 't Hoen, P. A. C., Boomsma, D. I., ... BIOS Consortium (2018). Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation. Nature Communications, 9(1), Article 3738. https://doi.org/10.1038/s41467-018-05714-3
    • Wyers, C. E., Reijven, P. L. M., Breedveld-Peters, J. J. L., Denissen, K. F. M., Schotanus, M. G. M., van Dongen, M. C. J. M., Eussen, S. J. P. M., Heyligers, I. C., van den Brandt, P. A., Willems, P. C., van Helden, S., & Dagnelie, P. C. (2018). Efficacy of Nutritional Intervention in Elderly After Hip Fracture: A Multicenter Randomized Controlled Trial. Journals of Gerontology Series A-Biological Sciences and Medical Sciences, 73(10), 1429-1437. https://doi.org/10.1093/gerona/gly030
    • Smulders, M. W., Bekkers, S. C. A. M., van Cauteren, Y. J. M., Liefhebber, A., Vermeer, J. R., Vervuurt, J., van Dieijen-Visser, M. P., Mingels, A. M. A., Rocca, H.-P. B.-L., Dagnelie, P. C., Wildberger, J. E., Crijns, H. J. G. M., & Kietselaer, B. L. J. H. (2018). Risk stratification and role for additional diagnostic testing in patients with acute chest pain and normal high-sensitivity cardiac troponin levels. PLOS ONE, 13(9), Article e0203506. https://doi.org/10.1371/journal.pone.0203506
    • Ozcan, B., Rutters, F., Snoek, F. J., Roosendaal, M., Sijbrands, E. J., Elders, P. J. M., Holleman, F., Pijl, H., Tack, C. J., Abbink, E. J., de Valk, H. W., Wolffenbuttel, B. H. R., Stehouwer, C. D. A., Schaper, N. C., Dekker, J. M., Schram, M. T., & Diabet Peart Parelsnoer Initiative (2018). High Diabetes Distress Among Ethnic Minorities Is Not Explained by Metabolic, Cardiovascular, or Lifestyle Factors: Findings From the Dutch Diabetes Pearl Cohort. Diabetes Care, 41(9), 1854-1861. https://doi.org/10.2337/dc17-2181
    • Hodson, L., & Brouwers, M. C. G. J. (2018). Non-alcoholic fatty liver disease concerns with glucokinase activators. The Lancet Diabetes & Endocrinology, 6(9), 684-685. https://doi.org/10.1016/S2213-8587(18)30196-7
    • Wesselius, H. M., van den Ende, E. S., Alsma, J., ter Maaten, J. C., Schuit, S. C. E., Stassen, P. M., de Vries, O. J., Kaasjager, K. H. A. H., Haak, H. R., van Doormaal, F. F., Hoogerwerf, J. J., Terwee, C. B., van de Ven, P. M., Bosch, F. H., van Someren, E. J. W., Nanayakkara, P. W. B., & Onderzoeks Consortium Acute Genees (2018). Quality and Quantity of Sleep and Factors Associated With Sleep Disturbance in Hospitalized Patients. JAMA Internal Medicine, 178(9), 1201-1208. https://doi.org/10.1001/jamainternmed.2018.2669
    • van Twist, D. J. L., de Leeuw, P. W., & Kroon, A. A. (2018). Renal artery fibromuscular dysplasia and its effect on the kidney. Hypertension Research, 41(9), 639-648. https://doi.org/10.1038/s41440-018-0063-z