• 2018
    • Huijbregts, S. C. J., Bosch, A. M., Simons, Q. A., Jahja, R., Brouwers, M. C. G. J., De Sonneville, L. M. J., De Vries, M. C., Hofstede, F. C., Hollak, C. E. M., Janssen, M. C. H., Langendonk, J. G., Rubio-Gozalbo, M. E., Van der Meere, J. J., Van der Ploeg, A. T., & Van Spronsen, F. J. (2018). The impact of metabolic control and tetrahydrobiopterin treatment on health related quality of life of patients with early-treated phenylketonuria: A PKU-COBESO study. Molecular Genetics and Metabolism, 125(1-2), 96-103. https://doi.org/10.1016/j.ymgme.2018.07.002
    • Geijselaers, S. L. C., Sep, S. J. S., Schram, M. T., van Boxtel, M. P. J., van Sloten, T. T., Roodt, J. O. H., Henry, R. M. A., Reesink, K. D., Schaper, N. C., Dagnelie, P. C., van der Kallen, C. J. H., Biessels, G. J., & Stehouwer, C. D. A. (2018). Carotid circumferential wall stress is not associated with cognitive performance among individuals in late middle age: The Maastricht Study. Atherosclerosis, 276, 15-22. https://doi.org/10.1016/j.atherosclerosis.2018.07.003
    • Hertroijs, D. F. L., Elissen, A. M. J., Brouwers, M. C. G. J., Schaper, N. C., & Ruwaard, D. (2018). Relevant patient characteristics for guiding tailored integrated diabetes primary care: a systematic review. Primary health care research & development, 19(5), 424-447. https://doi.org/10.1017/S146342361800004X
    • de Waard, E. A. C., Sarodnik, C., Pennings, A., de Jong, J. J. A., Savelberg, H. H. C. M., van Geel, T. A., van der Kallen, C. J., Stehouwer, C. D. A., Schram, M. T., Schaper, N., Dagnelie, P. C., Geusens, P. P. M. M., Koster, A., van Rietbergen, B., & van den Bergh, J. P. W. (2018). Reliability of HR-pQCT Derived Cortical Bone Structural Parameters When Using Uncorrected Instead of Corrected Automatically Generated Endocortical Contours in a Cross-Sectional Study: The Maastricht Study. Calcified Tissue International, 103(3), 252-265. https://doi.org/10.1007/s00223-018-0416-2
    • Vangrieken, P., Al-Nasiry, S., Janssen, G. M. J., Weseler, A. R., Spaanderman, M. E., Bast, A., & Schiffers, P. M. H. (2018). The direct and sustained consequences of severe placental hypoxia on vascular contractility. PLOS ONE, 13(8), Article e0202648. https://doi.org/10.1371/journal.pone.0202648
    • Luijk, R., Dekkers, K. F., van Iterson, M., Arindrarto, W., Claringbould, A., Hop, P., Boomsma, D., van Duijn, C. M., van Greevenbroek, M. M. J., Veldink, J. H., Wijmenga, C., Franke, L., 't Hoend, P. A. C., Jansen, R., van Meurs, J., Mei, H., Slagboomi, P. E., Heijmans, B. T., van Zwet, E. W., & BIOS Consortium (2018). Genome-wide identification of directed gene networks using large-scale population genomics data. Nature Communications, 9(1), Article 3097. https://doi.org/10.1038/s41467-018-05452-6
    • van Twist, D. J. L., de Heer, P. W. M., Houben, A. J. H. M., de Haan, M. W., de Leeuw, P. W., & Kroon, A. A. (2018). Differences in renal hemodynamics and renin secretion between patients with unifocal and multifocal fibromuscular dysplasia. Journal of Hypertension, 36(8), 1729-1735. https://doi.org/10.1097/HJH.0000000000001755
    • Hanssen, N. M. J., Westerink, J., Scheijen, J. L. J. M., van der Graaf, Y., Stehouwer, C. D. A., Schalkwijk, C. G., & SMART Study Grp (2018). Higher Plasma Methylglyoxal Levels Are Associated With Incident Cardiovascular Disease and Mortality in Individuals With Type 2 Diabetes. Diabetes Care, 41(8), 1689-1695. https://doi.org/10.2337/dc18-0159
    • Out, M., Top, W. M. C., Lehert, P., Schalkwijk, C. A., Stehouwer, C. D. A., & Kooy, A. (2018). Long-term treatment with metformin in type 2 diabetes and vitamin D levels: A post-hoc analysis of a randomized placebo-controlled trial. Diabetes Obesity & Metabolism, 20(8), 1951-1956. https://doi.org/10.1111/dom.13327
    • Brinkhues, S., Dukers-Muijrers, N. H. T. M., Hoebe, C. J. P. A., van der Kallen, C. J. H., Koster, A., Henry, R. M. A., Stehouwer, C. D. A., Savelkoul, P. H. M., Schaper, N. C., & Schram, M. T. (2018). Social Network Characteristics Are Associated With Type 2 Diabetes Complications: The Maastricht Study. Diabetes Care, 41(8), 1654-1662. https://doi.org/10.2337/dc17-2144
    • Eussen, S. J. P. M., van Dongen, M. C. J. M., Wijckmans, N. E. G., Meijboom, S., Brants, H. A. M., de Vries, J. H. M., Bueno-de-Mesquita, H. B., Geelen, A., Sluik, D., Feskens, E. J. M., Ocke, M. C., & Dagnelie, P. C. (2018). A national FFQ for the Netherlands (the FFQ-NL1.0): development and compatibility with existing Dutch FFQs. Public Health Nutrition, 21(12), 2221-2229. https://doi.org/10.1017/S1368980018000885
    • Veugen, M. G. J., Henry, R. M. A., Brunner-La Rocca, H.-P., Dagnelie, P. C., Schram, M. T., van Agtmaal, M. J. M., van der Kallen, C. J. H., Sep, S. J. S., van Boxtel, M. P. J., Bekers, O., Meex, S. J. R., Jansen, J. F. A., Kroon, A. A., & Stehouwer, C. D. A. (2018). Cross-sectional associations between cardiac biomarkers, cognitive performance, and structural brain changes are modified by age: The Maastricht Study. Arteriosclerosis Thrombosis and Vascular Biology, 38(8), 1948-1958. https://doi.org/10.1161/ATVBAHA.118.311082
    • Brinkhues, S., Schram, M. T., Hoebe, C. J. P. A., Kretzschmar, M. E. E., Koster, A., Dagnelie, P. C., Sep, S. J. S., van Kuijk, S. M. J., Savelkoul, P. H. M., & Dukers-Muijrers, N. H. T. M. (2018). Social networks in relation to self-reported symptomatic infections in individuals aged 40-75-the Maastricht study -. BMC Infectious Diseases, 18(1), Article 300. https://doi.org/10.1186/s12879-018-3197-3
    • Rensma, S. P., van Sloten, T. T., Launer, L. J., & Stehouwer, C. D. A. (2018). Cerebral small vessel disease and risk of incident stroke, dementia and depression, and all-cause mortality: A systematic review and meta-analysis. Neuroscience and Biobehavioral Reviews, 90, 164-173. https://doi.org/10.1016/j.neubiorev.2018.04.003
    • Sedaghat, S., van Sloten, T. T., Laurent, S., London, G. M., Pannier, B., Kavousi, M., Mattace-Raso, F., Franco, O. H., Boutouyrie, P., Ikram, M. A., & Stehouwer, C. D. A. (2018). Common Carotid Artery Diameter and Risk of Cardiovascular Events and Mortality: Pooled Analyses of Four Cohort Studies. Hypertension, 72(1), 85-92. https://doi.org/10.1161/HYPERTENSIONAHA.118.11253
    • Bijnen, M., Josefs, T., Cuijpers, I., Maalsen, C. J., van de Gaar, J., Vroomen, M., Wijnands, E., Rensen, S. S., Greve, J. W. M., Hofker, M. H., Biessen, E. A. L., Stehouwer, C. D. A., Schalkwijk, C. G., & Wouters, K. (2018). Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice. Gut, 67(7), 1317-1327. https://doi.org/10.1136/gutjnl-2016-313654
    • Talbot, C. P. J., Plat, J., Joris, P. J., Konings, M., Kusters, Y. H. A. M., Schalkwijk, C. G., Ritsch, A., & Mensink, R. P. (2018). HDL cholesterol efflux capacity and cholesteryl ester transfer are associated with body mass, but are not changed by diet-induced weight loss: A randomized trial in abdominally obese men. Atherosclerosis, 274, 23-28. https://doi.org/10.1016/j.atherosclerosis.2018.04.029
    • Duvivier, B. M. F. M., Bolijn, J. E., Koster, A., Schalkwijk, C. G., Savelberg, H. H. C. M., & Schaper, N. C. (2018). Reducing sitting time versus adding exercise: differential effects on biomarkers of endothelial dysfunction and metabolic risk. Scientific Reports, 8(1), Article 8657. https://doi.org/10.1038/s41598-018-26616-w
    • Nielen, J. T. H., Emans, P. J., van den Bemt, B., Dagnelie, P. C., Schram, M. T., Stehouwer, C. D. A., Schaper, N. C., Denissen, K. F. M., de Vries, F., & Boonen, A. (2018). Association of type 2 diabetes mellitus with self-reported knee pain and clinical knee osteoarthritis: The Maastricht Study. Diabetes & Metabolism, 44(3), 296-299. https://doi.org/10.1016/j.diabet.2018.01.013
    • Scheijen, J. L. J. M., Hanssen, N. M. J., van Greevenbroek, M. M., van der Kallen, C. J., Feskens, E. J. M., Stehouwer, C. D. A., & Schalkwijk, C. G. (2018). Dietary intake of advanced glycation endproducts is associated with higher levels of advanced glycation endproducts in plasma and urine: The CODAM study. Clinical Nutrition, 37(3), 919-925. https://doi.org/10.1016/j.clnu.2017.03.019
    • Smelt, A. F. H., Gussekloo, J., Bermingham, L. W., Allen, E., Dangour, A. D., Eussen, S. J. P. M., Favrat, B., De Groot, L. C. P. G. M., Kok, F. J., Kwok, T., Mangoni, A. A., Ntaios, G., Van de Rest, O., Seal, E., Vaucher, P., Verhoef, P., Stijnen, T., & Den Elzen, W. P. J. (2018). The effect of vitamin B12 and folic acid supplementation on routine haematological parameters in older people: an individual participant data meta-analysis. European Journal of Clinical Nutrition, 72(6), 785-795. https://doi.org/10.1038/s41430-018-0118-x
    • van Bussel, B. C. T., Henry, R. M. A., Schalkwijk, C. G., Dekker, J. M., Nijpels, G., Feskens, E. J. M., & Stehouwer, C. D. A. (2018). Alcohol and red wine consumption, but not fruit, vegetables, fish or dairy products, are associated with less endothelial dysfunction and less low-grade inflammation: the Hoorn Study. European Journal of Nutrition, 57(4), 1409-1419. https://doi.org/10.1007/s00394-017-1420-4
    • Meesters, A., Den Bosch-Meevissen, Y. M. C. I., Weijzen, C. A. H., Buurman, W. A., Losen, M., Schepers, J., Thissen, M. R. T. M., Alberts, H. J. E. M., Schalkwijk, C. G., & Peters, M. L. (2018). The effect of Mindfulness-Based Stress Reduction on wound healing: a preliminary study. Journal of Behavioral Medicine, 41(3), 385-397. https://doi.org/10.1007/s10865-017-9901-8
    • Wetzels, S., Wouters, K., Miyata, T., Scheijen, J. L. J. M., Hendriks, J. J. A., Schalkwijk, C. G., & Vanmierlo, T. (2018). Advanced Glycation Endproducts Are Increased in the Animal Model of Multiple Sclerosis but Cannot Be Reduced by Pyridoxamine Treatment or Glyoxalase 1 Overexpression. International journal of molecular sciences, 19(5), Article 1311. https://doi.org/10.3390/ijms19051311
    • Hertle, E., Arts, I. C. W., van der Kallen, C. J. H., Feskens, E. J. M., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2018). Classical Pathway of Complement Activation: Longitudinal Associations of C1q and C1-INH With Cardiovascular Outcomes: The CODAM Study (Cohort on Diabetes and Atherosclerosis Maastricht)Brief Report. Arteriosclerosis Thrombosis and Vascular Biology, 38(5), 1242-1244. https://doi.org/10.1161/ATVBAHA.118.310806
    • Xin, Y., Hertle, E., van der Kallen, C. J. H., Schalkwijk, C. G., Stehouwer, C. D. A., & van Greevenbroek, M. M. J. (2018). Longitudinal associations of the alternative and terminal pathways of complement activation with adiposity: The CODAM study. Obesity Research & Clinical Practice, 12(3), 286-292. https://doi.org/10.1016/j.orcp.2017.11.002
    • Martens, R. J. H., Houben, A. J. H. M., Kooman, J. P., Berendschot, T. T. J. M., Dagnelie, P. C., van der Kallen, C. J. H., Kroon, A. A., Leunissen, K. M. L., van der Sande, F. M., Schaper, N. C., Schouten, J. S. A. G., Schram, M. T., Sep, S. J. S., Sörensen, B. M., Henry, R. M. A., & Stehouwer, C. D. A. (2018). Microvascular endothelial dysfunction is associated with albuminuria: the Maastricht Study. Journal of Hypertension, 36(5), 1178-1187. https://doi.org/10.1097/HJH.0000000000001674
    • Martens, R. J. H., van der Berg, J. D., Stehouwer, C. D. A., Henry, R. M. A., Bosma, H., Dagnelie, P. C., van Dongen, M. C. J. M., Eussen, S. J. P. M., Schram, M. T., Sep, S. J. S., van der Kellen, C. J. H., Schaper, N. C., Savelberg, H. H. C. M., van der Sande, F. M., Kroon, A. A., Kooman, J. P., & Koster, A. (2018). Amount and pattern of physical activity and sedentary behavior are associated with kidney function and kidney damage: The Maastricht Study. PLOS ONE, 13(4), Article 0195306. https://doi.org/10.1371/journal.pone.0195306
    • de Leeuw, P. W., Postma, C. T., Spiering, W., & Kroon, A. A. (2018). Atherosclerotic Renal Artery Stenosis: Should we Intervene Earlier?Current Hypertension Reports, 20(4), Article 35. https://doi.org/10.1007/s11906-018-0829-3
    • Bellahcene, A., Nokin, M.-J., Castronovo, V., & Schalkwijk, C. (2018). Methylglyoxal-derived stress: An emerging biological factor involved in the onset and progression of cancer. Seminars in Cancer Biology, 49, 64-74. https://doi.org/10.1016/j.semcancer.2017.05.010
    • Pulakka, A., Stenholm, S., Bosma, H., Schaper, N. C., Savelberg, H. H. C. M., Stehouwer, C. D. A., van der Kallen, C. J. H., Dagnelie, P. C., Sep, S. J. S., & Koster, A. (2018). Association Between Employment Status and Objectively Measured Physical Activity and Sedentary BehaviorThe Maastricht Study. Journal of Occupational and Environmental Medicine, 60(4), 309-315. https://doi.org/10.1097/JOM.0000000000001254
    • Brinkhues, S., van Kuijk, S., Hoebe, C., Savelkoul, P., Kretzschmar, M. E. E., Jansen, M., de Vries, N., Sep, S., Dagnelie, P., Schaper, N., Verhey, F., Bosma, H., Maes, J., Schram, M., & Dukers-Muijrers, N. (2018). Development of prediction models for upper and lower respiratory and gastrointestinal tract infections using social network parameters in middle-aged and older persons: The Maastricht Study. Epidemiology and Infection, 146(5), 533-543. https://doi.org/10.1017/S0950268817002187
    • van Dalem, J., Brouwers, M. C. G. J., Stehouwer, C. D. A., Krings, A., Klungel, O. H., Driessen, J. H. M., de Vries, F., & Burden, A. M. (2018). Risk of a first-ever acute myocardial infarction and all-cause mortality with sulphonylurea treatment: A population-based cohort study. Diabetes Obesity & Metabolism, 20(4), 1056-1060. https://doi.org/10.1111/dom.13168
    • Fazelzadeh, P., Hangelbroek, R. W. J., Joris, P. J., Schalkwijk, C. G., Esser, D., Afman, L., Hankemeier, T., Jacobs, D. M., Mihaleva, V. V., Kersten, S., Van Duynhoven, J., & Boekschoten, M. V. (2018). Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects. Metabolomics, 14(4), Article 46. https://doi.org/10.1007/s11306-018-1328-x
    • Zwakenberg, S. R., van der Schouw, Y. T., Schalkwijk, C. G., Spijkerman, A. M. W., & Beulens, J. W. J. (2018). Bone markers and cardiovascular risk in type 2 diabetes patients. Cardiovascular Diabetology, 17(1), Article 45. https://doi.org/10.1186/s12933-018-0691-2
    • Verboven, K., Wouters, K., Gaens, K., Hansen, D., Bijnen, M., Wetzels, S., Stehouwer, C. D., Goossens, G. H., Schalkwijk, C. G., Blaak, E. E., & Jocken, J. W. (2018). Abdominal subcutaneous and visceral adipocyte size, lipolysis and inflammation relate to insulin resistance in male obese humans. Scientific Reports, 8(1), Article 4677. https://doi.org/10.1038/s41598-018-22962-x
    • Onete, V., Henry, R. M., Sep, S. J. S., Koster, A., van der Kallen, C. J., Dagnelie, P. C., Schaper, N., Kohler, S., Reesink, K., Stehouwer, C. D. A., & Schram, M. T. (2018). Arterial stiffness is associated with depression in middle-aged men - the Maastricht Study. Journal of Psychiatry & Neuroscience, 43(2), 111-119. https://doi.org/10.1503/jpn.160246
    • Peeters, S. A., Engelen, L., Buijs, J., Theilade, S., Rossing, P., Schalkwijk, C. G., & Stehouwer, C. D. A. (2018). Associations between advanced glycation endproducts and matrix metalloproteinases and its inhibitor in individuals with type 1 diabetes. Journal of Diabetes and Its Complications, 32(3), 325-329. https://doi.org/10.1016/j.jdiacomp.2017.12.011
    • Wetzels, S., Bijnen, M., Wijnands, E., Biessen, E. A. L., Schalkwijk, C. G., & Wouters, K. (2018). Characterization of Immune Cells in Human Adipose Tissue by Using Flow Cytometry. Journal of visualized experiment, (133), Article e57319 . https://doi.org/10.3791/57319
    • Gemmink, A., Daemen, S., Brouwers, B., Huntjens, P. R., Schaart, G., Moonen-Kornips, E., Jorgensen, J., Hoeks, J., Schrauwen, P., & Hesselink, M. K. C. (2018). Dissociation of intramyocellular lipid storage and insulin resistance in trained athletes and type 2 diabetes patients; involvement of perilipin 5?Journal of Physiology, 596(5), 857-868. https://doi.org/10.1113/JP275182
    • Hertroijs, D. FL., Elissen, A. MJ., Brouwers, M. CGJ., Schaper, N. C., Köhler, S., Popa, M. C., Asteriadis, S., Hendriks, S. H., Bilo, H. J., & Ruwaard, D. (2018). A risk score including body mass index, glycated haemoglobin and triglycerides predicts future glycaemic control in people with type 2 diabetes. Diabetes, Obesity and Metabolism, 20(3), 681-688. https://doi.org/10.1111/dom.13148
    • De Clerck, E. E. B., Schouten, J. S. A. G., Berendschot, T. T. J. M., Goezinne, F., Dagnelie, P. C., Schaper, N. C., Schram, M. T., Stehouwer, C. D. A., & Webers, C. A. B. (2018). Macular thinning in prediabetes or type 2 diabetes without diabetic retinopathy: the Maastricht Study. Acta Ophthalmologica, 96(2), 174-182. https://doi.org/10.1111/aos.13570
    • Daemen, S., van Polanen, N., & Hesselink, M. K. C. (2018). The effect of diet and exercise on lipid droplet dynamics in human muscle tissue. Journal of Experimental Biology, 221, Article 167015. https://doi.org/10.1242/jeb.167015
    • De Clerck, E. E. B., Schouten, J. S. A. G., Berendschot, T. T. J. M., Goezinne, F., Liesenborghs, I., Dagnelie, P. C., Schaper, N. C., Kroon, A. A., Henry, R. M. A., Reesink, K. D., Schram, M. T., Stehouwer, C. D. A., & Webers, C. A. B. (2018). Vascular risk factors for optical coherence tomography-detected cystoid macular edema: the Maastricht study. Acta Ophthalmologica, 96, 25-25.
    • Nielen, J. T. H., Boonen, A., Dagnelie, P. C., van den Bemt, B. J. F., Emans, P. J., Lafeber, F. P. J. G., van Spil, W. E., de Vries, F., & Welsing, P. M. J. (2018). Disease burden of knee osteoarthritis patients with a joint replacement compared to matched controls: a population-based analysis of a Dutch medical claims database. Osteoarthritis and Cartilage, 26(2), 202-210. https://doi.org/10.1016/j.joca.2017.11.012
    • Uiterwijk, R., Staals, J., Huijts, M., de Leeuw, P. W., Kroon, A. A., & van Oostenbrugge, R. J. (2018). Framingham Stroke Risk Profile is related to cerebral small vessel disease progression and lower cognitive performance in patients with hypertension. Journal of Clinical Hypertension, 20(2), 240-245. https://doi.org/10.1111/jch.13175
    • Out, M., Kooy, A., Lehert, P., Schalkwijk, C. A., & Stehouwer, C. D. A. (2018). Long-term treatment with metformin in type 2 diabetes and methylmalonic acid: Post hoc analysis of a randomized controlled 4.3 year trial. Journal of Diabetes and Its Complications, 32(2), 171-178. https://doi.org/10.1016/j.jdiacomp.2017.11.001
    • Zhang, M., Schiffers, P., Janssen, G., Vrolijk, M., Vangrieken, P., & Haenen, G. R. M. M. (2018). The cardiovascular side effects of Ma Huang due to its use in isolation in the Western world. European Journal of Integrative Medicine, 18, 18-22. https://doi.org/10.1016/j.eujim.2018.01.007
    • Schutten, M. T. J., Kusters, Y. H. A. M., Houben, A. J. H. M., Scheijen, J. L. J. M., van de Waarenburg, M. P. H., Schalkwijk, C. G., Joris, P. J., Plat, J., Mensink, R. P., de Leeuw, P. W., & Stehouwer, C. D. A. (2018). Aldosterone Is Not Associated With Metabolic and Microvascular Insulin Sensitivity in Abdominally Obese Men. Journal of Clinical Endocrinology & Metabolism, 103(2), 759-767. https://doi.org/10.1210/jc.2017-01541
    • Zhou, T. L., Reesink, K., Schram, M., Koster, A., Schaper, N., Dagnelie, P., van der Kallen, C., Sep, S., Stehouwer, C., & Henry, R. (2018). Blood pressure variability in individuals with and without (pre)diabetes: the Maastricht Study. Journal of Hypertension, 36(2), 259-267. https://doi.org/10.1097/HJH.0000000000001543