• 2014
    • Marsch, E., Theelen, T. L., Demandt, J. A., Jeurissen, M., van Gink, M., Verjans, R., Janssen, A., Cleutjens, J. P., Meex, S. J., Donners, M. M., Haenen, G., Schalkwijk, C. G., Dubois, L. J., Lambin, P., Mallat, Z., Gijbels, M. J., Heemskerk, J. W., Fisher, E. A., Biessen, E. A., ... Sluimer, J. C. (2014). Reversal of hypoxia in murine atherosclerosis prevents necrotic core expansion by enhancing efferocytosis. Arteriosclerosis Thrombosis and Vascular Biology, 34(12), 2545-2553. https://doi.org/10.1161/ATVBAHA.114.304023
    • Ruijters, E. J., Haenen, G. R., Weseler, A. R., & Bast, A. (2014). The cocoa flavanol (-)-epicatechin protects the cortisol response.Pharmacological Research, 79, 28-33. https://doi.org/10.1016/j.phrs.2013.11.004
    • Lemmens, K. J., Vrolijk, M. F., Bouwman, F. G., van der Vijgh, W. J., Bast, A., & Haenen, G. R. (2014). The Minor Structural Difference between the Antioxidants Quercetin and 4'O-Methylquercetin Has a Major Impact on Their Selective Thiol. International journal of molecular sciences, 15(5), 7475-7484. https://doi.org/10.3390/ijms15057475
    • Brouwers, O., Niessen, P. M. G., Miyata, T., Ostergaard, J. A., Flyvbjerg, A., Peutz-Kootstra, C. J., Sieber, J., Mundel, P. H., Brownlee, M., Janssen, B. J. A., De Mey, J. G. R., Stehouwer, C. D. A., & Schalkwijk, C. G. (2014). Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes. Diabetologia, 57(1), 224-235. https://doi.org/10.1007/s00125-013-3088-5
    • Sanders-van Wijk, S., Maeder, M. T., Nietlispach, F., Rickli, H., Estlinbaum, W., Erne, P., Rickenbacher, P., Peter, M., Pfisterer, M. P., & Brunner-La Rocca, H.-P. (2014). Long-Term Results of Intensified, N-Terminal-Pro-B-Type Natriuretic Peptide-Guided Versus Symptom-Guided Treatment in Elderly Patients With Heart Failure Five-Year Follow-Up From TIME-CHF. Circulation-Heart Failure, 7(1), 131-139. https://doi.org/10.1161/CIRCHEARTFAILURE.113.000527
    • Hohl, M., Ardehali, H., Azuaje, F. J., Breckenridge, R. A., Doehner, W., Eaton, P., Ehret, G. B., Fujita, T., Gaetani, R., Giacca, M., Hasenfuss, G., Heymans, S., Leite-Moreira, A. F., Linke, W. A., Linz, D., Lyon, A., Mamas, M. A., Oresic, M., Papp, Z., ... Maack, C. (2014). Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research. European journal of heart failure, 16(1), 6-14. https://doi.org/10.1002/ejhf.10
    • Mafi Rad, M., Blaauw, Y., Debie, L., Brunner-La Rocca, H., & Vernooy, K. (2014). Evaluation of Left Ventricular Endocardial Cardiac Resynchronization Therapy in a Non-responder with Ventricular Arrhythmias. Indian pacing and electrophysiology journal, 14(1), 32-6. https://doi.org/10.1016/S0972-6292(16)30713-6
    • van Dongen, M., van Kraaij, D., Schalla, S., Brunner-La Rocca, H., & Driessen, R. (2014). Severe mitral regurgitation caused by eosinophilic endocarditis. Journal of Cardiology Cases, 10(3). https://doi.org/10.1016/j.jccase.2014.05.012
    • van Buchem, M. A., Biessels, G. J., la Rocca, H. P. B., de Craen, A. J. M., van der Flier, W. M., Ikram, M. A., Kappelle, L. J., Koudstaal, P. J., Mooijaart, S. P., Niessen, W., van Oostenbrugge, R., de Roos, A., van Rossum, A. C., & Daemen, M. J. A. P. (2014). The Heart-Brain Connection: A Multidisciplinary Approach Targeting a Missing Link in the Pathophysiology of Vascular Cognitive Impairment. Journal of Alzheimer's Disease, 42, S443-S451. https://doi.org/10.3233/JAD-141542
  • 2013
    • Arends, S. J., Damoiseaux, J. G., Duijvestijn, A. M., Debrus-Palmans, L., Vroomen, M., Boomars, K. A., Brunner-La Rocca, H. P., Reutelingsperger, C. P., Tervaert, J. W., & van Paassen, P. (2013). Immunoglobulin G anti-endothelial cell antibodies: inducers of endothelial cell apoptosis in pulmonary arterial hypertension?Clinical and Experimental Immunology, 174(3), 433-440. https://doi.org/10.1111/cei.12166
    • Kuster, D. W. D., Mulders, J., ten Cate, F. J., Michels, M., dos Remedios, C. G., Martins, P. A. D. C., van der Velden, J., & Oudejans, C. B. M. (2013). MicroRNA transcriptome profiling in cardiac tissue of hypertrophic cardiomyopathy patients with MYBPC3 mutations. Journal of Molecular and Cellular Cardiology, 65, 59-66. https://doi.org/10.1016/j.yjmcc.2013.09.012
    • Dirkx, E., da Costa Martins, P. A., & De Windt, L. J. (2013). Regulation of fetal gene expression in heart failure. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1832(12), 2414-2424. https://doi.org/10.1016/j.bbadis.2013.07.023
    • Dirkx, E., Gladka, M. M., Philippen, L. E., Armand, A.-S., Kinet, V., Leptidis, S., el Azzouzi, H., Salic, K., Bourajjaj, M., da Silva, G. J. J., Olieslagers, S., van der Nagel, R., de Weger, R., Bitsch, N., Kisters, N., Seyen, S., Morikawa, Y., Chanoine, C., Heymans, S., ... De Windt, L. J. (2013). Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure. Nature Cell Biology, 15(11), 1282-1293. https://doi.org/10.1038/ncb2866
    • Maeder, M. T., Rickenbacher, P., Rickli, H., Abbuehl, H., Gutmann, M., Erne, P., Vuilliomenet, A., Peter, M., Pfisterer, M., & Brunner-La Rocca, H.-P. (2013). N-terminal pro brain natriuretic peptide-guided management in patients with heart failure and preserved ejection fraction: findings from the Trial of Intensified versus standard Medical therapy in Elderly patients with Congestive Heart Failure (TIME-CHF). European journal of heart failure, 15(10), 1148-1156. https://doi.org/10.1093/eurjhf/hft076
    • Ruijters, E. J. B., Weseler, A. R., Kicken, C., Haenen, G. R. M. M., & Bast, A. (2013). The flavanol (-)-epicatechin and its metabolites protect against oxidative stress in primary endothelial cells via a direct antioxidant effect.European Journal of Pharmacology, 715(1-3), 147-153. https://doi.org/10.1016/j.ejphar.2013.05.029
    • El Azzouzi, H., Leptidis, S., Dirkx, E., Hoeks, J., van Bree, B., van de Brand, K., McClellan, E. A., Poels, E., Sluimer, J. C., van den Hoogenhof, M. M., Armand, A. S., Yin, X., Langley, S., Bourajjaj, M., Olieslagers, S., Krishnan, J., Vooijs, M., Kurihara, H., Stubbs, A., ... De Windt, L. J. (2013). The Hypoxia-Inducible MicroRNA Cluster miR-199a similar to 214 Targets Myocardial PPAR delta and Impairs Mitochondrial Fatty Acid Oxidation. Cell Metabolism, 18(3), 341-354. https://doi.org/10.1016/j.cmet.2013.08.009
    • Caforio, A. L. P., Pankuweit, S., Arbustini, E., Basso, C., Gimeno-Blanes, J., Felix, S. B., Fu, M., Helio, T., Heymans, S., Jahns, R., Klingel, K., Linhart, A., Maisch, B., McKenna, W., Mogensen, J., Pinto, Y. M., Ristic, A., Schultheiss, H.-P., Seggewiss, H., ... Elliott, P. M. (2013). Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. European Heart Journal, 34(33), 2636-2648. https://doi.org/10.1093/eurheartj/eht210
    • van de Wier, B., Balk, J. M., Haenen, G. R. M. M., Giamouridis, D., Bakker, J. A., Bast, B. C., den Hartog, G. J. M., Koek, G. H., & Bast, A. (2013). Elevated citrate levels in non-alcoholic fatty liver disease: The potential of citrate to promote radical production. Febs Letters, 587(15), 2461-2466. https://doi.org/10.1016/j.febslet.2013.06.019
    • Witjas-Paalberends, E. R., Piroddi, N., Stam, K., van Dijk, S. J., Oliviera, V. S., Ferrara, C., Scellini, B., Hazebroek, M., ten Cate, F. J., van Slegtenhorst, M., dos Remedios, C., Niessen, H. W. M., Tesi, C., Stienen, G. J. M., Heymans, S., Michels, M., Poggesi, C., & van der Velden, J. (2013). Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy. Cardiovascular Research, 99(3), 432-441. https://doi.org/10.1093/cvr/cvt119
    • Van Aelst, L. N. L., & Heymans, S. (2013). MicroRNAs as Biomarkers for Ischemic Heart Disease. Journal of Cardiovascular Translational Research, 6(4), 458-470. https://doi.org/10.1007/s12265-013-9466-z
    • Brouwers, O., de Vos-Houben, J. M., Niessen, P. M., Miyata, T., van Nieuwenhoven, F., Janssen, B. J., Hageman, G., Stehouwer, C. D., & Schalkwijk, C. G. (2013). Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression. International Journal of Molecular Sciences, 14(8), 15724-15739. https://doi.org/10.3390/ijms140815724
    • Sanders-van Wijk, S., Muzzarelli, S., Neuhaus, M., Kiencke, S., Maeder, M., Estlinbaum, W., Tobler, D., Mayer, K., Erne, P., Pfisterer, M. E., & Brunner-La Rocca, H.-P. (2013). Safety and tolerability of intensified, N-terminal pro brain natriuretic peptide-guided compared with standard medical therapy in elderly patients with congestive heart failure: results from TIME-CHF. European journal of heart failure, 15(8), 910-918. https://doi.org/10.1093/eurjhf/hft079
    • Vanhoutte, D., van Almen, G. C., Van Aelst, L. N. L., Van Cleemput, J., Droogne, W., Jin, Y., Van de Werf, F., Carmeliet, P., Vanhaecke, J., Papageorgiou, A.-P., & Heymans, S. (2013). Matricellular proteins and matrix metalloproteinases mark the inflammatory and fibrotic response in human cardiac allograft rejection. European Heart Journal, 34(25), 1930-1941. https://doi.org/10.1093/eurheartj/ehs375
    • Lok, S. I., van Mil, A., Bovenschen, N., van der Weide, P., van Kuik, J., van Wichen, D., Peeters, T., Siera, E., Winkens, B., Sluijter, J. P. G., Doevendans, P. A., Martins, P. A. D. C., de Jonge, N., & de Weger, R. A. (2013). Post-transcriptional Regulation of a-1-Antichymotrypsin by MicroRNA-137 in Chronic Heart Failure and Mechanical Support. Circulation-Heart Failure, 6(4), 853-861. https://doi.org/10.1161/CIRCHEARTFAILURE.112.000255
    • Tritsch, E., Mallat, Y., Lefebvre, F., Diguet, N., Escoubet, B., Blanc, J., De Windt, L. J., Catalucci, D., Vandecasteele, G., Li, Z., & Mericskay, M. (2013). An SRF/miR-1 axis regulates NCX1 and Annexin A5 protein levels in the normal and failing heart. Cardiovascular Research, 98(3), 372-380. https://doi.org/10.1093/cvr/cvt042
    • Res, P. T., Cermak, N. M., Stinkens, R. E., Tollakson, T. J., Haenen, G. R. M. M., Bast, A., & van Loon, L. J. C. (2013). Astaxanthin supplementation does not augment fat use or improve endurance performance.Medicine and Science in Sports and Exercise, 45(6), 1158-1165. https://doi.org/10.1249/MSS.0b013e31827fddc4
    • Huijts, M., van Oostenbrugge, R. J., Duits, A., Burkard, T., Muzzarelli, S., Maeder, M. T., Schindler, R., Pfisterer, M. E., & Brunner-La Rocca, H.-P. (2013). Cognitive impairment in heart failure: results from the Trial of Intensified versus standard Medical therapy in Elderly patients with Congestive Heart Failure (TIME-CHF) randomized trial. European journal of heart failure, 15(6), 699-707. https://doi.org/10.1093/eurjhf/hft020
    • VanTeeffelen, J. W. G. E., Brands, J., Janssen, B. J. A., & Vink, H. (2013). Effect of acute hyaluronidase treatment of the glycocalyx on tracer-based whole body vascular volume estimates in mice. Journal of Applied Physiology, 114(9), 1132-1140. https://doi.org/10.1152/japplphysiol.00842.2012
    • Daskalopoulos, E. P., Hermans, K. C. M., Janssen, B. J. A., & Blankesteijn, W. M. (2013). Targeting the Wnt/frizzled signaling pathway after myocardial infarction: A new tool in the therapeutic toolbox?Trends in Cardiovascular Medicine, 23(4), 121-127. https://doi.org/10.1016/j.tcm.2012.09.010
    • Stapf, D., Franke, A., Schreckenberg, M., Schummers, G., Mischke, K., Marx, N., Schauerte, P., & Knackstedt, C. (2013). Beat to beat 3-dimensional intracardiac echocardiography: theoretical approach and practical experiences. International Journal of Cardiovascular Imaging, 29(4), 753-764. https://doi.org/10.1007/s10554-012-0136-z
    • Mischke, K., Knackstedt, C., Marx, N., & Vollmann, D. (2013). Insights into atrial fibrillation. Minerva Medica, 104(2), 119-130.
    • Vanhees, K., van Schooten, F. J., van Waalwijk van Doorn-Khosrovani, S. B., van Helden, S. H., Munnia, A., Peluso, M., Briedé, J. J., Haenen, G. R. M. M., & Godschalk, R. W. L. (2013). Intrauterine exposure to flavonoids modifies antioxidant status at adulthood and decreases oxidative stress-induced DNA damage. Free Radical Biology and Medicine, 57, 154-161. https://doi.org/10.1016/j.freeradbiomed.2012.12.021
    • Camporeale, A., Marino, F., Papageorgiou, A., Carai, P., Fornero, S., Fletcher, S., Page, B. D. G., Gunning, P., Forni, M., Chiarle, R., Morello, M., Jensen, O., Levi, R., Heymans, S., & Poli, V. (2013). STAT3 activity is necessary and sufficient for the development of immune-mediated myocarditis in mice and promotes progression to dilated cardiomyopathy. EMBO Molecular Medicine, 5(4), 572-590. https://doi.org/10.1002/emmm.201201876
    • Aleksinskaya, M. A., van Faassen, E. E. H., Nelissen, J., Janssen, B. J. A., De Mey, J. G. R., Hanemaaijer, R., Rabelink, T., & van Zonneveld, A. J. (2013). Identification of Free Nitric Oxide Radicals in Rat Bone Marrow: Implications for Progenitor Cell Mobilization in Hypertension. PLOS ONE, 8(3), Article e57761. https://doi.org/10.1371/journal.pone.0057761
    • Kaufmann, B. A., Min, S. Y., Goetschalckx, K., Bernheim, A. M., Buser, P. T., Pfisterer, M. E., & Brunner-La Rocca, H.-P. (2013). How reliable are left ventricular ejection fraction cut offs assessed by echocardiography for clinical decision making in patients with heart failure?International Journal of Cardiovascular Imaging, 29(3), 581-588. https://doi.org/10.1007/s10554-012-0122-5
    • Heijnen, B. F. J., Nelissen, J., van Essen, H., Fazzi, G. E., Tervaert, J. W. C., Peutz-Kootstra, C. J., Mullins, J. J., Schalkwijk, C. G., Janssen, B. J. A., & Struijker-Boudier, H. A. J. (2013). Irreversible Renal Damage after Transient Renin-Angiotensin System Stimulation: Involvement of an AT(1)-Receptor Mediated Immune Response. PLOS ONE, 8(2), Article e57815. https://doi.org/10.1371/journal.pone.0057815
    • Leptidis, S., el Azzouzi, H., Lok, S. I., de Weger, R., Olieslagers, S., Kisters, N., Silva, G. J., Heymans, S., Cuppen, E., Berezikov, E., De Windt, L. J., & Martins, P. D. C. (2013). A Deep Sequencing Approach to Uncover the miRNOME in the Human Heart. PLOS ONE, 8(2), Article e57800. https://doi.org/10.1371/journal.pone.0057800
    • Borissoff, J. I., Otten, J. J. T., Heeneman, S., Leenders, P., van Oerle, R., Soehnlein, O., Loubele, S. T. B. G., Hamulyak, K., Hackeng, T. M., Daemen, M. J. A. P., Degen, J. L., Weiler, H., Esmon, C. T., van Ryn, J., Biessen, E. A. L., Spronk, H. M. H., & ten Cate, H. (2013). Genetic and Pharmacological Modifications of Thrombin Formation in Apolipoprotein E-deficient Mice Determine Atherosclerosis Severity and Atherothrombosis Onset in a Neutrophil-Dependent Manner. PLOS ONE, 8(2), Article e55784. https://doi.org/10.1371/journal.pone.0055784
    • Nergiz-Unal, R., Kuijpers, M. J. E., de Witt, S. M., Heeneman, S., Feijge, M. A. H., Garcia Caraballo, S., Biessen, E. A., Haenen, G. R. M. M., Cosemans, J. M., & Heemskerk, J. W. (2013). Atheroprotective effect of dietary walnut intake in ApoE-deficient mice: Involvement of lipids and coagulation factors.Thrombosis Research, 131(5), 411-417. https://doi.org/10.1016/j.thromres.2013.01.003
    • Klinkenberg, L. J., Res, P. T., Haenen, G. R., Bast, A., van Loon, L. J., van Dieijen-Visser, M. P., & Meex, S. J. (2013). Effect of antioxidant supplementation on exercise-induced cardiac troponin release in cyclists: a randomized trial. PLOS ONE, 8(11), Article e79280. https://doi.org/10.1371/journal.pone.0079280
    • Arends, S. J., Damoiseaux, J. G., Duijvestijn, A. M., Debrus-Palmans, L., Boomars, K. A., Brunner-La Rocca, H. P., Tervaert, J. W., & van Paassen, P. (2013). Functional implications of IgG anti-endothelial cell antibodies in pulmonary arterial hypertension. Autoimmunity, 46(7), 463-470. https://doi.org/10.3109/08916934.2013.812080
    • Bast, A., & Haenen, G. R. M. M. (2013). Ten misconceptions about antioxidants. Trends in Pharmacological Sciences, 34(8), 430-436. https://doi.org/10.1016/j.tips.2013.05.010
    • Smulders, M. W., Kietselaer, B. L. J. H., Das, M., Wildberger, J. E., Crijns, H. J. G. M., Veenstra, L., Brunner La Rocca, H. P., van Dieijen-Visser, M. P., Mingels, A. M. A., Dagnelie, P. C., Post, M. J., Gorgels, A. P. M., van Asselt, A. D. I., Vogel, G., Schalla, S., Kim, R. J., & Bekkers, S. C. A. M. (2013). The role of cardiovascular magnetic resonance imaging and computed tomography angiography in suspected non-ST-elevation myocardial infarction patients: Design and rationale of the CARdiovascular Magnetic rEsoNance imaging and computed Tomography Angiography (CARMENTA) trial. American Heart Journal, 166(6), 968-975. https://doi.org/10.1016/j.ahj.2013.09.012
    • Jeger, R. V., Rocca, H. P. B.-L., Bertel, O., Kiowski, W., Pfisterer, M. E., & Kaiser, C. A. (2013). Stent Thrombosis after Coronary Stent Implantation: A Protective Effect of High-Dose Statin Therapy?Cardiology, 126(2), 115-121. https://doi.org/10.1159/000350822