Publications
- 2012
- van Empel, V. P. M., De Windt, L. J., & Martins, P. A. D. C. (2012). Circulating miRNAs: Reflecting or Affecting Cardiovascular Disease?Current Hypertension Reports, 14(6), 498-509. https://doi.org/10.1007/s11906-012-0310-7
- Scharf, C., Ng, G. A., Wieczorek, M., Deneke, T., Furniss, S. S., Murray, S., Debruyne, P., Hobson, N., Berntsen, R. F., Schneider, M. A., Hauer, H. A., Halimi, F., Boveda, S., Asbach, S., Boesche, L., Zimmermann, M., Brigadeau, F., Taieb, J., Merkel, M., ... Boersma, L. V. A. (2012). European survey on efficacy and safety of duty-cycled radiofrequency ablation for atrial fibrillation. EP Europace, 14(12), 1700-1707. https://doi.org/10.1093/europace/eus188
- Spruit, M. A., Maeder, M. T., Knackstedt, C., Ammann, P., Jeker, U., Uszko-Lencer, N., Kiencke, S., Pfisterer, M. E., Rickli, H., & Brunner La Rocca, H. P. (2012). Prognostic Value of Self-Reported Versus Objectively Measured Functional Capacity in Patients With Heart Failure Results From the TIME-CHF (Trial of Intensified Versus Standard Medical Therapy in Elderly Patients With Congestive Heart Failure). Journal of the American College of Cardiology, 60(20), 2125-2126. https://doi.org/10.1016/j.jacc.2012.08.968
- Lemkens, P., Nelissen, J., Meens, M. J. P. M. T., Fazzi, G. E., Janssen, G. J. M., Debets, J. J. M., Janssen, B. J. A., Schiffers, P. M. H., & De Mey, J. G. R. (2012). Impaired flow-induced arterial remodeling in DOCA-salt hypertensive rats. Hypertension Research, 35(11), 1093-1101. https://doi.org/10.1038/hr.2012.94
- Heggermont, W. A., & Heymans, S. (2012). MicroRNAs Are Involved in End-Organ Damage During Hypertension. Hypertension, 60(5), 1088-1093. https://doi.org/10.1161/HYPERTENSIONAHA.111.187104
- Bourgonje, V. J. A., Schoenmakers, M., Beekman, J. D. M., van der Nagel, R., Houtman, M. J. C., Miedema, L. F., Antoons, G., Sipido, K., de Windt, L. J., van Veen, T. A. B., & Vos, M. A. (2012). Relevance of calmodulin/CaMKII activation for arrhythmogenesis in the AV block dog. Heart Rhythm, 9(11), 1875-1883.e2. https://doi.org/10.1016/j.hrthm.2012.07.023
- Rickenbacher, P., Pfisterer, M., Burkard, T., Kiowski, W., Follath, F., Burckhardt, D., Schindler, R., & Rocca, H.-P. B.-L. (2012). Why and how do elderly patients with heart failure die? Insights from the TIME-CHF study. European journal of heart failure, 14(11), 1218-1229. https://doi.org/10.1093/eurjhf/hfs113
- Eurlings, L. W., van Wijk, S., van Kimmenade, R., Osinski, A., van Helmond, L., Vallinga, M., Crijns, H. J., van Dieijen-Visser, M. P., Brunner La Rocca, H. P., & Pinto, Y. M. (2012). Multimarker strategy for short-term risk assessment in patients with dyspnea in the emergency department: The marked (multi marker emergency dyspnea)-risk score. Journal of the American College of Cardiology, 60(17), 1668-1677. https://doi.org/10.1016/j.jacc.2012.06.040
- Nelissen, J., Lemkens, P., Sann, H., Bindl, M., Bassissi, F., Jasserand, D., De Mey, J. G. R., & Janssen, B. J. A. (2012). Pharmacokinetic and pharmacodynamic properties of SOL1: A novel dual inhibitor of neutral endopeptidase and endothelin converting enzyme. Life Sciences, 91(13-14), 587-592. https://doi.org/10.1016/j.lfs.2012.01.015
- Lemkens, P., Nelissen, J., Meens, M. J. P. M. T., Janssen, B. J. A., Schiffers, P. M. H., & De Mey, J. G. R. (2012). Dual neural peptidase/endothelin-converting enzyme inhibition improves endothelial function in mesenteric resistance arteries of young spontaneously hypertensive rats. Journal of Hypertension, 30(9), 1799-1808. https://doi.org/10.1097/HJH.0b013e3283569c7a
- Totzeck, M., Hendgen-Cotta, U. B., Rammos, C., Frommke, L.-M., Knackstedt, C., Predel, H.-G., Kelm, M., & Rassaf, T. (2012). Higher endogenous nitrite levels are associated with superior exercise capacity in highly trained athletes. Nitric Oxide-Biology and Chemistry, 27(2), 75-81. https://doi.org/10.1016/j.niox.2012.05.003
- Knackstedt, C., Becker, M., Mischke, K., Pauling, R., Rocca, H. P. B.-L., & Schauerte, P. (2012). A dedicated cardioversion unit for the treatment of atrial fibrillation. Reducing costs by optimizing processes. Herz, 37(5), 518-526. https://doi.org/10.1007/s00059-011-3546-0
- Dennert, R., van Paassen, P., Wolffs, P., Bruggeman, C., Velthuis, S., Felix, S., van Suylen, R.-J., Crijns, H. J., Tervaert, J. W. C., & Heymans, S. (2012). Differences in Virus Prevalence and Load in the Hearts of Patients with Idiopathic Dilated Cardiomyopathy with and without Immune-Mediated Inflammatory Diseases. Clinical and Vaccine Immunology, 19(8), 1182-1187. https://doi.org/10.1128/CVI.00281-12
- Hazebroek, M., Dennert, R., & Heymans, S. (2012). Idiopathic dilated cardiomyopathy: possible triggers and treatment strategies. Netherlands Heart Journal, 20(7-8), 332-335. https://doi.org/10.1007/s12471-012-0285-7
- Timmers, S., Nabben, M., Bosma, M., van Bree, B., Lenaers, E., Van Beurden, D., Schaart, G., Westerterp-Plantenga, M. S., Langhans, W., Hesselink, M. K. C., Schrauwen-Hinderling, V. B., & Schrauwen, P. (2012). Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America, 109(29), 11711-11716. https://doi.org/10.1073/pnas.1206868109
- Corsten, M. F., Schroen, B., & Heymans, S. (2012). Inflammation in viral myocarditis: friend or foe?Trends in Molecular Medicine, 18(7), 426-437. https://doi.org/10.1016/j.molmed.2012.05.005
- Boots, A. W., Gerloff, K., Bartholomé, R., van Berlo, D., Ledermann, K., Haenen, G. R. M. M., Bast, A., van Schooten, F. J., Albrecht, C., & Schins, R. P. (2012). Neutrophils augment LPS-mediated pro-inflammatory signaling in human lung epithelial cells. Biochimica et Biophysica Acta-Molecular Cell Research, 1823(7), 1151-1162. https://doi.org/10.1016/j.bbamcr.2012.04.012
- Altenhofer, S., Kleikers, P. W. M., Radermacher, K. A., Scheurer, P., Hermans, J. J. R., Schiffers, P., Ho, H., Wingler, K., & Schmidt, H. H. H. W. (2012). The NOX toolbox: validating the role of NADPH oxidases in physiology and disease. Cellular and Molecular Life Sciences, 69(14), 2327-2343. https://doi.org/10.1007/s00018-012-1010-9
- el Azzouzi, H., Leptidis, S., Bourajjaj, M., van Bilsen, M., Martins, P. A. D. C., & De Windt, L. J. (2012). MEK1 Inhibits Cardiac PPAR alpha Activity by Direct Interaction and Prevents Its Nuclear Localization. PLOS ONE, 7(6), Article e36799. https://doi.org/10.1371/journal.pone.0036799
- Daamen, M. A. M. J., Hamers, J. P. H., Gorgels, A. P. M., Brunner-La Rocca, H. P., Tan, F. E. S., van Dieijen-Visser, M. P., & Schols, J. M. G. A. (2012). The prevalence and management of heart failure in Dutch nursing homes: design of a multi-centre cross-sectional study. BMC Geriatrics, 12, Article 29. https://doi.org/10.1186/1471-2318-12-29
- Salic, K., & De Windt, L. J. (2012). MicroRNAs as Biomarkers for Myocardial Infarction. Current Atherosclerosis Reports, 14(3), 193-200. https://doi.org/10.1007/s11883-012-0238-z
- Fransen, G. A. J., Mesters, I., Muris, J. W. M., Van Marrewijk, C. J., Mujakovic, S., Laheij, R. J. F., Numans, M. E., De Wit, N. J., Samsom, M., Jansen, J. B. M. J., & Knottnerus, J. A. (2012). Patient adherence to prescribed medication instructions for dyspepsia: The DIAMOND-study. European Journal of General Practice, 18(2), 79-85. https://doi.org/10.3109/13814788.2012.665443
- Tivig, C., Dang, L., Brunner-La Rocca, H.-P., Oezcan, S., Duru, F., & Scharf, C. (2012). Duty-cycled unipolar/bipolar versus conventional radiofrequency ablation in paroxysmal and persistent atrial fibrillation. International Journal of Cardiology, 157(2), 185-191. https://doi.org/10.1016/j.ijcard.2010.12.010
- Hazewindus, M., Haenen, G. R. M. M., Weseler, A. R., & Bast, A. (2012). The anti-inflammatory effect of lycopene complements the antioxidant action of ascorbic acid and alpha-tocopherol. Food Chemistry, 132(2), 954-958. https://doi.org/10.1016/j.foodchem.2011.11.075
- Papageorgiou, A.-P., & Heymans, S. (2012). Interactions between the extracellular matrix and inflammation during viral myocarditis. Immunobiology, 217(5), 503-510. https://doi.org/10.1016/j.imbio.2011.07.011
- Seemann, I., Gabriels, K., Visser, N. L., Hoving, S., te Poele, J. A., Pol, J. F., Gijbels, M. J., Janssen, B. J., Van Leeuwen, F. W., Daemen, M. J., Heeneman, S., & Stewart, F. A. (2012). Irradiation induced modest changes in murine cardiac function despite progressive structural damage to the myocardium and microvasculature. Radiotherapy and Oncology, 103(2), 143-150. https://doi.org/10.1016/j.radonc.2011.10.011
- Donners, M. M. P. C., Wolfs, I. M. J., Stoger, L. J., van der Vorst, E. P. C., Pottgens, C. C. H., Heymans, S., Schroen, B., Gijbels, M. J. J., & de Winther, M. P. J. (2012). Hematopoietic miR155 Deficiency Enhances Atherosclerosis and Decreases Plaque Stability in Hyperlipidemic Mice. PLOS ONE, 7(4), Article e35877. https://doi.org/10.1371/journal.pone.0035877
- Papageorgiou, A.-P., Swinnen, M., Vanhoutte, D., VandenDriessche, T., Chuah, M., Lindner, D., Verhesen, W., de Vries, B., D'hooge, J., Lutgens, E., Westermann, D., Carmeliet, P., & Heymans, S. (2012). Thrombospondin-2 prevents cardiac injury and dysfunction in viral myocarditis through the activation of regulatory T-cells. Cardiovascular Research, 94(1), 115-124. https://doi.org/10.1093/cvr/cvs077
- Jin, Y., Kuznetsova, T., Thijs, L., Schmitz, B., Liu, Y., Asayama, K., Brand, S.-M., Heymans, S., Brand, E., Fagard, R., & Staessen, J. A. (2012). Association of Left Ventricular Mass With the AGTR1 A1166C Polymorphism. American Journal of Hypertension, 25(4), 472-478. https://doi.org/10.1038/ajh.2011.244
- Martins, P. A. D. C., & De Windt, L. J. (2012). MicroRNAs in control of cardiac hypertrophy. Cardiovascular Research, 93(4), 563-572. https://doi.org/10.1093/cvr/cvs013
- Schroen, B., & Heymans, S. (2012). Small but smart-microRNAs in the centre of inflammatory processes during cardiovascular diseases, the metabolic syndrome, and ageing. Cardiovascular Research, 93(4), 605-613. https://doi.org/10.1093/cvr/cvr268
- Muzzarelli, S., Maeder, M. T., Toggweiler, S., Rickli, H., Nietlispach, F., Julius, B., Burkard, T., Pfisterer, M. E., & Brunner-La Rocca, H.-P. (2012). Frequency and Predictors of Hyperkalemia in Patients >= 60 Years of Age With Heart Failure Undergoing Intense Medical Therapy. American Journal of Cardiology, 109(5), 693-698. https://doi.org/10.1016/j.amjcard.2011.10.027
- Burkard, T., Kaiser, C. A., Brunner-La Rocca, H., Osswald, S., Pfisterer, M. E., & Jeger, R. V. (2012). Combined clopidogrel and proton pump inhibitor therapy is associated with higher cardiovascular event rates after percutaneous coronary intervention: a report from the BASKET trial. Journal of Internal Medicine, 271(3), 257-263. https://doi.org/10.1111/j.1365-2796.2011.02423.x
- Maeder, M. T., Rickli, H., Pfisterer, M. E., Muzzarelli, S., Ammann, P., Fehr, T., Hack, D., Weilenmann, D., Dieterle, T., Kiencke, S., Estlinbaum, W., & Brunner-La Rocca, H.-P. (2012). Incidence, clinical predictors, and prognostic impact of worsening renal function in elderly patients with chronic heart failure on intensive medical therapy. American Heart Journal, 163(3), 407-U353. https://doi.org/10.1016/j.ahj.2011.12.003
- Devaux, Y., Vausort, M., Goretti, E., Nazarov, P. V., Azuaje, F., Gilson, G., Corsten, M. F., Schroen, B., Lair, M.-L., Heymans, S., & Wagner, D. R. (2012). Use of Circulating MicroRNAs to Diagnose Acute Myocardial Infarction. Clinical Chemistry, 58(3), 559-567. https://doi.org/10.1373/clinchem.2011.173823
- Zellweger, M. J., Kaiser, C. A., Jeger, R. V., Brunner-La Rocca, H.-P., Buser, P. T., Bader, F., Mueller-Brand, J., & Pfisterer, M. E. (2012). Coronary Artery Disease Progression Late After Successful Stent Implantation. Journal of the American College of Cardiology, 59(9), 793-799. https://doi.org/10.1016/j.jacc.2011.11.024
- Daskalopoulos, E. P., Janssen, B. J. A., & Blankesteijn, W. M. (2012). Myofibroblasts in the Infarct Area: Concepts and Challenges. Microscopy and Microanalysis, 18(1), 35-49. https://doi.org/10.1017/S143192761101227X
- Heijman, J., Spätjens, R. L. H., Seyen, S. R. M., Lentink, V., Kuijpers, H. J. H., Boulet, I. R., de Windt, L. J., David, M., & Volders, P. G. A. (2012). Dominant-Negative Control of cAMP-Dependent I-Ks Upregulation in Human Long-QT Syndrome Type 1. Circulation Research, 110(2), 211–219. https://doi.org/10.1161/CIRCRESAHA.111.249482
- Octavia, Y., Rocca, H. P. B.-L., & Moens, A. L. (2012). NADPH oxidase-dependent oxidative stress in the failing heart: From pathogenic roles to therapeutic approach. Free Radical Biology and Medicine, 52(2), 291-297. https://doi.org/10.1016/j.freeradbiomed.2011.10.482
- Moalin, M., van Strijdonck, G. P., Bast, A., & Haenen, G. R. M. M. (2012). Competition between Ascorbate and Glutathione for the Oxidized Form of Methylated Quercetin Metabolites and Analogues: Tamarixetin, 4'O-Methylquercetin, Has the Lowest Thiol Reactivity. Journal of Agricultural and Food Chemistry, 60(36), 9292-9297. https://doi.org/10.1021/jf302068v
- Mateo Anson, N., Hemery, Y. M., Bast, A., & Haenen, G. R. M. M. (2012). Optimizing the bioactive potential of wheat bran by processing. Food & Function, 3(4), 362-375. https://doi.org/10.1039/c2fo10241b
- van den Heuvel, M. G. W., Bast, A., Haenen, G. R. M. M., Ambergen, A. W., Mermans, J. F., & van der Hulst, R. R. W. J. (2012). The role of antioxidants in ischaemia-reperfusion in a human DIEP flap model. Journal of Plastic Reconstructive and Aesthetic Surgery, 65(12), 1706-1711. https://doi.org/10.1016/j.bjps.2012.06.010
- van Wijk, S., Jacobs, L., Eurlings, L. W., van Kimmenade, R., Lemmers, R., Broos, P., Bekers, O., Prins, M. H., Crijns, H. J., Pinto, Y. M., van Dieijen-Visser, M. P., & Brunner-La Rocca, H. P. (2012). Troponin T Measurements by High-Sensitivity vs Conventional Assays for Risk Stratification in Acute Dyspnea. Clinical Chemistry, 58(1), 284-292. https://doi.org/10.1373/clinchem.2011.175976
- Gladka, M. M., Martins, P. A. D. C., & de Windt, L. J. (2012). Small changes can make a big difference - MicroRNA regulation of cardiac hypertrophy. Journal of Molecular and Cellular Cardiology, 52(1), 74-82. https://doi.org/10.1016/j.yjmcc.2011.09.015
- ter Horst, P., Smits, J. F. M., & Blankesteijn, W. M. (2012). The Wnt/Frizzled pathway as a therapeutic target for cardiac hypertrophy: where do we stand. Acta Physiologica, 204(1), 110-117. https://doi.org/10.1111/j.1748-1716.2011.02309.x
- Halbach, N. S. J., Smeets, E. E. J., Bierau, J., Keularts, I. M. L. W., Plasqui, G., Julu, P. O. O., Engerström, I. W., Bakker, J. A., & Curfs, L. M. G. (2012). Altered carbon dioxide metabolism and creatine abnormalities in rett syndrome. JIMD reports, 3, 117-24. https://doi.org/10.1007/8904_2011_76
- 2011
- Spijkers, L. J. A., Janssen, B. J. A., Nelissen, J., Meens, M. J. P. M. T., Wijesinghe, D. S., Chalfant, C. E., De Mey, J. G. R., Alewijnse, A. E., & Peters, S. L. M. (2011). Antihypertensive Treatment Differentially Affects Vascular Sphingolipid Biology in Spontaneously Hypertensive Rats. PLOS ONE, 6(12), Article e29222. https://doi.org/10.1371/journal.pone.0029222
- Nabben, M., Hoeks, J., Kornips, C. F. P., Van Beurden, D., Briedé, J. J., Hesselink, M. K. C., Glatz, J. F., & Schrauwen, P. (2011). Significance of uncoupling protein 3 in mitochondrial function upon mid- and long-term dietary high-fat exposure. Febs Letters, 585(24), 4010-4017. https://doi.org/10.1016/j.febslet.2011.11.012
- Weseler, A. R., Ruijters, E. J. B., Reesink, K. D., Haenen, G. R. M. M., & Bast, A. (2011). Pleiotropic benefit of monomeric and oligomeric flavanols on vascular health - a randomized controlled clinical pilot study. PLOS ONE, 6(12), Article 28460. https://doi.org/10.1371/journal.pone.0028460