• 2012
    • Mitchell, G. F., Verwoert, G. C., Tarasov, K. V., Isaacs, A., Smith, A. V., Yasmin, Rietzschel, E. R., Tanaka, T., Liu, Y., Parsa, A., Najjar, S. S., O'Shaughnessy, K. M., Sigurdsson, S., De Buyzere, M. L., Larson, M. G., Sie, M. P. S., Andrews, J. S., Post, W. S., Mattace-Raso, F. U. S., ... Witteman, J. C. M. (2012). Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium. Circulation : Cardiovascular Genetics, 5(1), 81-90. https://doi.org/10.1161/CIRCGENETICS.111.959817
    • Janknegt, R., Ruiters, L., & ten Cate, H. (2012). InforMatrix: ADP antagonists in acute coronary syndromes. Expert Opinion on Pharmacotherapy, 13(3), 357-385. https://doi.org/10.1517/14656566.2012.651460
    • Knottnerus, I. L. H., Winckers, K., ten Cate, H., Hackeng, T. M., Lodder, J., Rouhl, R. P. W., Staals, J., Govers-Riemslag, J. W. P., Bekers, O., & van Oostenbrugge, R. J. (2012). Levels of heparin-releasable TFPI are increased in first-ever lacunar stroke patients. Neurology, 78(7), 493-498. https://doi.org/10.1212/WNL.0b013e318246d6b7
    • Vlassaks, E., Gavilanes, A. W. D., Bieghs, V., Reinartz, A., Gassler, N., van Gorp, P. J. J., Gijbels, M. J. J., Bekers, O., Zimmermann, L. J. I., Pillow, J. J., Polglase, G. R., Nitsos, I., Newnham, J. P., Kallapur, S. G., Jobe, A. H., Shiri-Sverdlov, R., & Kramer, B. W. (2012). Antenatal exposure to chorioamnionitis affects lipid metabolism in 7-week-old sheep. Journal of developmental origins of health and disease, 3(2), 103-110. https://doi.org/10.1017/S2040174412000049
    • Mingels, A. M., Gorgels, T. P., & van Dieijen-Visser, M. P. (2012). Cardiaal troponine. Nederlands Tijdschrift voor Geneeskunde, 156(42), A5044. http://www.ncbi.nlm.nih.gov/pubmed/23075777
    • Mingels, A. M. A., Gorgels, A. P. M., & van Dieijen-Visser, M. P. (2012). Eerdere diagnose van hartinfarct met hoogintensief troponineassay. Nederlands Tijdschrift voor Geneeskunde, 156(42: A5044), 1773-1774.
    • Mingels, A. M., Joosen, I. A., Versteylen, M. O., Laufer, E. M., Winkens, M. H., Wildberger, J. E., van Dieijen-Visser, M. P., & Hofstra, L. (2012). High-sensitivity cardiac troponin t: Risk stratification tool in patients with symptoms of chest discomfort. PLOS ONE, 7(4), Article e35059. https://doi.org/10.1371/journal.pone.0035059
    • van Bussel, B. C. T., Henry, R. M., Schalkwijk, C. G., Dekker, J. M., Nijpels, G., & Stehouwer, C. D. A. (2012). Low-grade inflammation, but not endothelial dysfunction, is associated with greater carotid stiffness in the elderly: the Hoorn Study. Journal of Hypertension, 30(4), 744-752. https://doi.org/10.1097/HJH.0b013e328350a487
    • van Dieijen-Visser, M. P., Mingels, A. M., Jacobs, L. H., Cardinaels, E. P., Wodzig, K. W. H., Bekers, O., Klinkenberg, L. J., & Meex, S. J. R. (2012). Troponin, the best there is!Nederlands tijdschrift voor klinische chemie en laboratoriumgeneeskunde, 37, 15-18.
    • van Wijk, S., Jacobs, L., Eurlings, L. W., van Kimmenade, R., Lemmers, R., Broos, P., Bekers, O., Prins, M. H., Crijns, H. J., Pinto, Y. M., van Dieijen-Visser, M. P., & Brunner-La Rocca, H. P. (2012). Troponin T Measurements by High-Sensitivity vs Conventional Assays for Risk Stratification in Acute Dyspnea. Clinical Chemistry, 58(1), 284-292. https://doi.org/10.1373/clinchem.2011.175976
    • Kanzler, I., Liehn, E. A., Koenen, R. R., & Weber, C. (2012). Anti-Inflammatory Therapeutic Approaches to Reduce Acute Atherosclerotic Complications. Current Pharmaceutical Biotechnology, 13(1), 37-45. https://doi.org/10.2174/138920112798868557
    • Segers, O., Simioni, P., Tormene, D., Bulato, C., Gavasso, S., Rosing, J., & Castoldi, E. (2012). Genetic modulation of the FVLeiden/normal FV ratio and risk of venous thrombosis in factor V Leiden heterozygotes. Journal of Thrombosis and Haemostasis, 10(1), 73-80. https://doi.org/10.1111/j.1538-7836.2011.04546.x
    • van Es, J., Mos, I., Douma, R., Erkens, P., Durian, M., Nizet, T., van Houten, A., Hofstee, H., ten Cate, H., Ullmann, E., Buller, H., Huisman, M., & Kamphuisen, P. W. (2012). The combination of four different clinical decision rules and an age-adjusted D-dimer cut-off increases the number of patients in whom acute pulmonary embolism can safely be excluded. Thrombosis and Haemostasis, 107(1), 167-171. https://doi.org/10.1160/TH11-08-0587
    • Bouman, H. J., van Werkum, J. W., Rudez, G., Hackeng, C. M., Leebeek, F. W. G., ten Cate, H., Ten Berg, J. M., & de Maat, M. P. M. (2012). The relevance of P2Y(12)-receptor gene variation for the outcome of clopidogrel-treated patients undergoing elective coronary stent implantation: A clinical follow-up. Thrombosis and Haemostasis, 107(1), 189-191. https://doi.org/10.1160/TH11-05-0306
    • Van de Vijver, P., Scheer, L., van Beijnum, J., Griffioen, A., & Hackeng, T. M. (2012). Application of an omonasteine ligation strategy for the total chemical synthesis of the BRD7 bromodomain. Chemical Communications, 48(75), 9403-9405. https://doi.org/10.1039/c2cc34956f
    • Kleinegris, M.-C., Ten Cate-Hoek, A. J., & ten Cate, H. (2012). Coagulation and the vessel wall in thrombosis and atherosclerosis. Polskie Archiwum Medycyny Wewnetrznej-Polish Archives of Internal Medicine, 122(11), 557-565. https://doi.org/10.20452/pamw.1464
    • Pattaro, C., Köttgen, A., Teumer, A., Garnaas, M., Böger, C. A., Fuchsberger, C., Olden, M., Chen, M.-H., Tin, A., Taliun, D., Li, M., Gao, X., Gorski, M., Yang, Q., Hundertmark, C., Foster, M. C., O'Seaghdha, C. M., Glazer, N., Isaacs, A., ... CARDIoGRAM Consortium (2012). Genome-wide association and functional follow-up reveals new loci for kidney function. Plos Genetics, 8(3), e1002584. https://doi.org/10.1371/journal.pgen.1002584
    • Demirkan, A., van Duijn, C. M., Ugocsai, P., Isaacs, A., Pramstaller, P. P., Liebisch, G., Wilson, J. F., Johansson, Å., Rudan, I., Aulchenko, Y. S., Kirichenko, A. V., Janssens, A. C. J. W., Jansen, R. C., Gnewuch, C., Domingues, F. S., Pattaro, C., Wild, S. H., Jonasson, I., Polasek, O., ... DIAGRAM Consortium (2012). Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. Plos Genetics, 8(2), e1002490. https://doi.org/10.1371/journal.pgen.1002490
    • Lance, M. D., Sloep, M., Henskens, Y. M. C., & Marcus, M. A. E. (2012). Mean Platelet Volume as a Diagnostic Marker for Cardiovascular Disease: Drawbacks of Preanalytical Conditions and Measuring Techniques. Clinical and Applied Thrombosis-Hemostasis, 18(6), 561-568. https://doi.org/10.1177/1076029612458147
    • Van Kruchten, R., Cosemans, J. M. E. M., & Heemskerk, J. W. M. (2012). Measurement of whole blood thrombus formation using parallel-plate flow chambers - a practical guide. Platelets, 23(3), 229-242. https://doi.org/10.3109/09537104.2011.630848
    • Westein, E., de Witt, S., Lamers, M., Cosemans, J. M. E. M., & Heemskerk, J. W. M. (2012). Monitoring in vitro thrombus formation with novel microfluidic devices. Platelets, 23(7), 501-509. https://doi.org/10.3109/09537104.2012.709653
    • Dastani, Z., Hivert, M.-F., Timpson, N., Perry, J. R. B., Yuan, X., Scott, R. A., Henneman, P., Heid, I. M., Kizer, J. R., Lyytikäinen, L.-P., Fuchsberger, C., Tanaka, T., Morris, A. P., Small, K., Isaacs, A., Beekman, M., Coassin, S., Lohman, K., Qi, L., ... DIAGRAM+ Consortium (2012). Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. Plos Genetics, 8(3), e1002607. https://doi.org/10.1371/journal.pgen.1002607
    • van Ballegooijen, A. J., Snijder, M. B., Visser, M., van den Hurk, K., Kamp, O., Dekker, J. M., Nijpels, G., Stehouwer, C. D. A., Henry, R. M. A., Paulus, W. J., & Brouwer, I. A. (2012). Vitamin D in Relation to Myocardial Structure and Function after Eight Years of Follow-Up: The Hoorn Study. Annals of Nutrition and Metabolism, 60(1), 69-77. https://doi.org/10.1159/000336173
  • 2011
    • Koenen, R. R., & Weber, C. (2011). Chemokines: established and novel targets in atherosclerosis. EMBO Molecular Medicine, 3(12), 713-725. https://doi.org/10.1002/emmm.201100183
    • Butoi, E. D., Gan, A. M., Manduteanu, I., Stan, D., Calin, M., Pirvulescu, M., Koenen, R. R., Weber, C., & Simionescu, M. (2011). Cross talk between smooth muscle cells and monocytes/activated monocytes via CX3CL1/CX3CR1 axis augments expression of pro-atherogenic molecules. Biochimica et Biophysica Acta-Molecular Cell Research, 1813(12), 2026-2035. https://doi.org/10.1016/j.bbamcr.2011.08.009
    • Kuijpers, M. J. E., Megens, R. T. A., Nikookhesal, E., Feijge, M. A. H., De Mey, J. G. R., Egbrink, M. G. A. O., van Giezen, J. J. J., & Heemskerk, J. W. M. (2011). Role of newly formed platelets in thrombus formation in rat after clopidogrel treatment: comparison to the reversible binding P2Y(12) antagonist ticagrelor. Thrombosis and Haemostasis, 106(6), 1179-1188. https://doi.org/10.1160/TH11-04-0252
    • Mahmoodi, B. K., Mulder, A. B., Waanders, F., Spronk, H. M. H., Mulder, E. R., Slagman, M. C. J., Vogt, L., Navis, G., Ten Cate, H., Kluin-Nelemans, H. C., & Laverman, G. D. (2011). The impact of antiproteinuric therapy on the prothrombotic state in patients with overt proteinuria. Journal of Thrombosis and Haemostasis, 9(12), 2416-2423. https://doi.org/10.1111/j.1538-7836.2011.04525.x
    • Wildhagen, K. C. A. A., Lutgens, E., Loubele, S. T. G. B., ten Cate, H., & Nicolaes, G. A. F. (2011). The structure-function relationship of activated protein C Lessons from natural and engineered mutations. Thrombosis and Haemostasis, 106(6), 1034-1045. https://doi.org/10.1160/TH11-08-0522
    • Liehn, E. A., Tuchscheerer, N., Kanzler, I., Drechsler, M., Fraemohs, L., Schuh, A., Koenen, R. R., Zander, S., Soehnlein, O., Hristov, M., Grigorescu, G., Urs, A. O., Leabu, M., Bucur, I., Merx, M. W., Zernecke, A., Ehling, J., Gremse, F., Lammers, T., ... Weber, C. (2011). Double-Edged Role of the CXCL12/CXCR4 Axis in Experimental Myocardial Infarction. Journal of the American College of Cardiology, 58(23), 2415-2423. https://doi.org/10.1016/j.jacc.2011.08.033
    • Winckers, K., Siegerink, B., Duckers, C., Maurissen, L. F., Tans, G., Castoldi, E., Spronk, H. M. H., Ten Cate, H., Algra, A., Hackeng, T. M., & Rosendaal, F. R. (2011). Increased tissue factor pathway inhibitor activity is associated with myocardial infarction in young women: results from the RATIO study. Journal of Thrombosis and Haemostasis, 9(11), 2243-2250. https://doi.org/10.1111/j.1538-7836.2011.04497.x
    • Tchaikovski, S. N., Thomassen, M. C. L. G. D., Costa, S.-D., Peeters, L. L. H., & Rosing, J. (2011). Role of protein S and tissue factor pathway inhibitor in the development of activated protein C resistance early in pregnancy in women with a history of preeclampsia. Thrombosis and Haemostasis, 106(5), 914-921. https://doi.org/10.1160/TH11-04-0244
    • Strijkers, R. H. W., Ten Cate-Hoek, A. J., Bukkems, S. F. F. W., & Wittens, C. H. A. (2011). Management of deep vein thrombosis and prevention of post-thrombotic syndrome. BMJ, 343(7830), 8. https://doi.org/10.1136/bmj.d5916
    • Laeremans, H., Hackeng, T. M., van Zandvoort, M. A. M. J., Thijssen, V. L. J. L., Janssen, B. J. A., Ottenheijm, H. C. J., Smits, J. F. M., & Blankesteijn, W. M. (2011). Blocking of Frizzled Signaling With a Homologous Peptide Fragment of Wnt3a/Wnt5a Reduces Infarct Expansion and Prevents the Development of Heart Failure After Myocardial Infarction. Circulation, 124(15), 1626-U107. https://doi.org/10.1161/CIRCULATIONAHA.110.976969
    • Konings, J., Govers-Riemslag, J. W. P., Philippou, H., Mutch, N. J., Borissoff, J. I., Allan, P., Mohan, S., Tans, G., ten Cate, H., & Ariens, R. A. S. (2011). Factor XIIa regulates the structure of the fibrin clot independently of thrombin generation through direct interaction with fibrin. Blood, 118(14), 3942-3951. https://doi.org/10.1182/blood-2011-03-339572
    • International Consortium for Blood Pressure Genome-Wide Association Studies (2011). Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature, 478(7367), 103-109. https://doi.org/10.1038/nature10405
    • Soehnlein, O., Wantha, S., Simsekyilmaz, S., Doering, Y., Megens, R. T. A., Mause, S. F., Drechsler, M., Smeets, R., Weinandy, S., Schreiber, F., Gries, T., Jockenhoevel, S., Moeller, M., Vijayan, S., van Zandvoort, M. A. M. J., Agerberth, B., Pham, C. C. T. N., Gallo, R. L., Hackeng, T. M., ... Weber, C. (2011). Neutrophil-Derived Cathelicidin Protects from Neointimal Hyperplasia. Science Translational Medicine, 3(103), 10. https://doi.org/10.1126/scitranslmed.3002531
    • Surakka, I., Isaacs, A., Karssen, L. C., Laurila, P.-P. P., Middelberg, R. P. S., Tikkanen, E., Ried, J. S., Lamina, C., Mangino, M., Igl, W., Hottenga, J.-J., Lagou, V., van der Harst, P., Mateo Leach, I., Esko, T., Kutalik, Z., Wainwright, N. W., Struchalin, M. V., Sarin, A.-P., ... ENGAGE Consortium (2011). A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. Plos Genetics, 7(10), e1002333. https://doi.org/10.1371/journal.pgen.1002333
    • Honickel, M., Rieg, A. D., Rossaint, R., Braunschweig, T., Spronk, H. M. H., ten Cate, H., van Oerle, R., Tolba, R., & Grottke, O. (2011). Prothrombin complex concentrate reduces blood loss and enhances thrombin generation in a pig model with blunt liver injury under severe hypothermia. Thrombosis and Haemostasis, 106(4), 724-733. https://doi.org/10.1160/TH11-02-0101
    • Bis, J. C., Kavousi, M., Franceschini, N., Isaacs, A., Abecasis, G. R., Schminke, U., Post, W. S., Smith, A. V., Cupples, L. A., Markus, H. S., Schmidt, R., Huffman, J. E., Lehtimäki, T., Baumert, J., Münzel, T., Heckbert, S. R., Dehghan, A., North, K., Oostra, B., ... CARDIoGRAM Consortium (2011). Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. Nature Genetics, 43(10), 940-7. https://doi.org/10.1038/ng.920
    • Panova-Noeva, M., Marchetti, M., Buoro, S., Russo, L., Leuzzi, A., Finazzi, G., Rambaldi, A., Ottomano, C., ten Cate, H., & Falanga, A. (2011). JAK2V617F mutation and hydroxyurea treatment as determinants of immature platelet parameters in essential thrombocythemia and polycythemia vera patients. Blood, 118(9), 2599-2601. https://doi.org/10.1182/blood-2011-02-339655
    • Schuur, M., Ikram, M. A., van Swieten, J. C., Isaacs, A., Vergeer-Drop, J. M., Hofman, A., Oostra, B. A., Breteler, M. M. B., & van Duijn, C. M. (2011). Cathepsin D gene and the risk of Alzheimer's disease: a population-based study and meta-analysis. Neurobiology of Aging, 32(9), 1607-14. https://doi.org/10.1016/j.neurobiolaging.2009.10.011
    • Panizzi, P., Nahrendorf, M., Figueiredo, J.-L., Panizzi, J., Marinelli, B., Iwamoto, Y., Keliher, E., Maddur, A. A., Waterman, P., Kroh, H. K., Leuschner, F., Aikawa, E., Swirski, F. K., Pittet, M. J., Hackeng, T. M., Fuentes-Prior, P., Schneewind, O., Bock, P. E., & Weissleder, R. (2011). In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation. Nature Medicine, 17(9), 1142-U153. https://doi.org/10.1038/nm.2423
    • Vasina, E. M., Cauwenberghs, S., Feijge, M. A. H., Heemskerk, J. W. M., Weber, C., & Koenen, R. R. (2011). Microparticles from apoptotic platelets promote resident macrophage differentiation. Cell Death & Disease, 2(9), 10. Article e211. https://doi.org/10.1038/cddis.2011.94
    • Nergiz-Unal, R., Lamers, M. M. E., Van Kruchten, R., Luiken, J. J., Cosemans, J. M. E. M., Glatz, J. F. C., Kuijpers, M. J. E., & Heemskerk, J. W. M. (2011). Signaling role of CD36 in platelet activation and thrombus formation on immobilized thrombospondin or oxidized low-density lipoprotein. Journal of Thrombosis and Haemostasis, 9(9), 1835-1846. https://doi.org/10.1111/j.1538-7836.2011.04416.x
    • Kornfeld, J.-W., Isaacs, A., Vitart, V., Pospisilik, J. A., Meitinger, T., Gyllensten, U., Wilson, J. F., Rudan, I., Campbell, H., Penninger, J. M., Sexl, V., Moriggl, R., van Duijn, C., Pramstaller, P. P., & Hicks, A. A. (2011). Variants in STAT5B associate with serum TC and LDL-C levels. Journal of Clinical Endocrinology & Metabolism, 96(9), E1496-501. https://doi.org/10.1210/jc.2011-0322
    • Grottke, O., Braunschweig, T., Spronk, H. M. H., Esch, S., Rieg, A. D., van Oerle, R., ten Cate, H., Fitzner, C., Tolba, R., & Rossaint, R. (2011). Increasing concentrations of prothrombin complex concentrate induce disseminated intravascular coagulation in a pig model of coagulopathy with blunt liver injury. Blood, 118(7), 1943-1951. https://doi.org/10.1182/blood-2011-03-343046