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Knottnerus, I. L. H., Govers-Riemslag, J. W. P., Hamulyak, K., Rouhl, R. P. W., Staals, J., Spronk, H. M. H., van Oerle, R., van Raak, E. P. M., Lodder, J., ten Cate, H., & van Oostenbrugge, R. J. (2010). Endothelial Activation in Lacunar Stroke Subtypes. Stroke, 41(8), 1617-1622. https://doi.org/10.1161/STROKEAHA.109.576223

Cosemans, J. M. E. M., Van Kruchten, R., Olieslagers, S., Schurgers, L. J., Verheyen, F. K., Munnix, I. C. A., Waltenberger, J., Angelillo-Scherrer, A., Hoylaerts, M. F., Carmeliet, P., & Heemskerk, J. W. M. (2010). Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization. Journal of Thrombosis and Haemostasis, 8(8), 1797-1808. https://doi.org/10.1111/j.1538-7836.2010.03935.x

Beckers, H. J. M., Ruven, H. J. T., Haas, F. J. L. M., Doevendans, P. A., ten Cate, H., Prins, M. H., & Biesma, D. H. (2010). Single nucleotide polymorphisms in inflammation-related genes are associated with venous thromboembolism. European journal of internal medicine, 21(4), 289-292. https://doi.org/10.1016/j.ejim.2010.04.001

Gilio, K., van Kruchten, R., Braun, A., Berna-Erro, A., Feijge, M. A. H., Stegner, D., van der Meijden, P. E. J., Kuijpers, M. J. E., Varga-Szabo, D., Heemskerk, J. W. M., & Nieswandt, B. (2010). Roles of Platelet STIM1 and Orai1 in Glycoprotein VI- and Thrombin-dependent Procoagulant Activity and Thrombus Formation. Journal of Biological Chemistry, 285(31), 23629-23638. https://doi.org/10.1074/jbc.M110.108696

Gilio, K., Harper, M. T., Cosemans, J. M. E. M., Konopatskaya, O., Munnix, I. C. A., Prinzen, L., Leitges, M., Liu, Q., Molkentin, J. D., Heemskerk, J. W. M., & Poole, A. W. (2010). Functional Divergence of Platelet Protein Kinase C (PKC) Isoforms in Thrombus Formation on Collagen. Journal of Biological Chemistry, 285(30), 23408-23417. https://doi.org/10.1074/jbc.M110.136176

Nicolaes, G. A. F., Bock, P. E., Segers, K., Wildhagen, K. C. A. A., Dahlback, B., & Rosing, J. (2010). Inhibition of Thrombin Formation by Active Site Mutated (S360A) Activated Protein C. Journal of Biological Chemistry, 285(30), 22888-22898. https://doi.org/10.1074/jbc.M110.131029

Loubele, S. T. B. G., ten Cate, H., & Spronk, H. M. H. (2010). Anticoagulant therapy in critical organ ischaemia/reperfusion injury. Thrombosis and Haemostasis, 104(1), 136-142. https://doi.org/10.1160/TH09-08-0582

Oostendorp, M., Douma, K., Hackeng, T. M., Post, M. J., van Zandvoort, M. A. M. J., & Backes, W. H. (2010). Gadolinium-Labeled Quantum Dots for Molecular Magnetic Resonance Imaging: R-1 Versus R-2 Mapping. Magnetic Resonance in Medicine, 64(1), 291-298. https://doi.org/10.1002/mrm.22342

ten Cate-Hoek, A. J., ten Cate, H., Tordoir, J., Hamulyak, K., & Prins, M. H. (2010). Individually tailored duration of elastic compression therapy in relation to incidence of the postthrombotic syndrome. Journal of Vascular Surgery, 52(1), 132-138. https://doi.org/10.1016/j.jvs.2010.01.089

Rennenberg, R. J. M. W., van Varik, B. J., Schurgers, L. J., Hamulyak, K., ten Cate, H., Leiner, T., Vermeer, C., de Leeuw, P. W., & Kroon, A. A. (2010). Chronic coumarin treatment is associated with increased extracoronary arterial calcification in humans. Blood, 115(24), 5121-5123. https://doi.org/10.1182/blood-2010-01-264598

Lind, J. S., Dingemans, A. M., Groen, H. J., Thunnissen, F. B., Bekers, O., Heideman, D. A., Honeywell, R. J., Giovannetti, E., Peters, G. J., Postmus, P. E., van Suylen, R. J., & Smit, E. F. (2010). A multicenter phase II study of erlotinib and sorafenib in chemotherapy-naive patients with advanced non-small cell lung cancer. Clinical Cancer Research, 16(11), 3078-3087. https://doi.org/10.1158/1078-0432.CCR-09-3033

Meens, M. J. P. M. T., Compeer, M. G., Hackeng, T. M., van Zandvoort, M. A., Janssen, B. J. A., & De Mey, J. G. R. (2010). Stimuli of Sensory-Motor Nerves Terminate Arterial Contractile Effects of Endothelin-1 by CGRP and Dissociation of ET-1/ETA-Receptor Complexes. PLOS ONE, 5(6), 11. https://doi.org/10.1371/journal.pone.0010917

Mingels, A. M. A., Jacobs, L. H. J., Kleijnen, V. W., Laufer, E. M., Winkens, B., Hofstra, L., Wodzig, W. K. W. H., & van Dieijen-Visser, M. P. (2010). Cardiac troponin T elevations, using highly sensitive assay, in recreational running depend on running distance. Clinical research in cardiology, 99(6), 385-391. https://doi.org/10.1007/s00392-010-0134-x

Elvers, M., Pozgaj, R., Pleines, I., May, F., Kuijpers, M. J. E., Heemskerk, J. M. W., Yu-Wai-Man, P., & Nieswandt, B. (2010). Platelet hyperreactivity and a prothrombotic phenotype in mice with a gain-of-function mutation in phospholipase C gamma 2. Journal of Thrombosis and Haemostasis, 8(6), 1353-1363. https://doi.org/10.1111/j.1538-7836.2010.03838.x

Laufer, E. M., Mingels, A. M. A., Winkens, M. H. M., Joosen, I. A. P. G., Schellings, M. W. M., Leiner, T., Wildberger, J. E., Narula, J., Van Dieijen-Visser, M. P., & Hofstra, L. (2010). The Extent of Coronary Atherosclerosis Is Associated With Increasing Circulating Levels of High Sensitive Cardiac Troponin T. Arteriosclerosis Thrombosis and Vascular Biology, 30(6), 1269-1275. https://doi.org/10.1161/ATVBAHA.109.200394

Berny, M. A., Munnix, I. C. A., Auger, J. M., Schols, S. E. M., Cosemans, J. M. E. M., Panizzi, P., Bock, P. E., Watson, S. P., McCarty, O. J. T., & Heemskerk, J. W. M. (2010). Spatial Distribution of Factor Xa, Thrombin, and Fibrin(ogen) on Thrombi at Venous Shear. PLOS ONE, 5(4), 8. https://doi.org/10.1371/journal.pone.0010415

Unal - Nergiz, R., Cosemans, J., Feijge, M., van der Meijden, P., Storey, R. F., van Giezen, J. J. J., Oude Egbrink, M., Heemskerk, J., & Kuijpers, M. (2010). Stabilizing Role of Platelet P2Y(12) Receptors in Shear-Dependent Thrombus Formation on Ruptured Plaques. PLOS ONE, 5(4), 1-13. Article e10130. https://doi.org/10.1371/journal.pone.0010130

Maurissen, L. F. A., Castoldi, E., Simioni, P., Rosing, J., & Hackeng, T. M. (2010). Thrombin generation-based assays to measure the activity of the TFPI-protein S pathway in plasma from normal and protein S-deficient individuals. Journal of Thrombosis and Haemostasis, 8(4), 750-758. https://doi.org/10.1111/j.1538-7836.2010.03743.x

Liu, Z., Lin, L., Yuan, C., Nicolaes, G. A. F., Chen, L., Meehan, E. J., Furie, B., Furie, B. C., & Huang, M. (2010). Trp(2313)-His(2315) of Factor VIII C2 Domain Is Involved in Membrane Binding STRUCTURE OF A COMPLEX BETWEEN THE C2 DOMAIN AND AN INHIBITOR OF MEMBRANE BINDING. Journal of Biological Chemistry, 285(12), 8824-8829. https://doi.org/10.1074/jbc.M109.080168

Castoldi, E., & Rosing, J. (2010). APC resistance: biological basis and acquired influences. Journal of Thrombosis and Haemostasis, 8(3), 445-453. https://doi.org/10.1111/j.1538-7836.2009.03711.x

Koenen, R. R., & Weber, C. (2010). Manipulating the chemokine system: Therapeutic perspectives for atherosclerosis. Current Opinion in Investigational Drugs, 11(3), 265-272.

Koenen, R. R., & Weber, C. (2010). Platelet-Derived Chemokines in Vascular Remodeling and Atherosclerosis. Seminars in Thrombosis and Hemostasis, 36(2), 163-169. https://doi.org/10.1055/s-0030-1251500

Wijnen, P. A., Nelemans, P. J., Verschakelen, J. A., Bekers, O., Voorter, C. E., & Drent, M. (2010). The role of tumor necrosis factor alpha G-308A polymorphisms in the course of pulmonary sarcoidosis.Tissue Antigens, 75(3), 262-268. https://doi.org/10.1111/j.1399-0039.2009.01437.x

Bouman, H. J., Parlak, E., van Werkum, J. W., Breet, N. J., ten Cate, H., Hackeng, C. M., Ten Berg, J. M., & Taubert, D. (2010). Which platelet function test is suitable to monitor clopidogrel responsiveness? A pharmacokinetic analysis on the active metabolite of clopidogrel. Journal of Thrombosis and Haemostasis, 8(3), 482-488. https://doi.org/10.1111/j.1538-7836.2009.03733.x

Oostendorp, M., Douma, K., Wagenaar, A., Slenter, J. M. G. M., Hackeng, T. M., van Zandvoort, M. A. M. J., Post, M. J., & Backes, W. H. (2010). Molecular Magnetic Resonance Imaging of Myocardial Angiogenesis After Acute Myocardial Infarction. Circulation, 121(6), 775-U85. https://doi.org/10.1161/CIRCULATIONAHA.109.889451

de Kruif, M. D., Limper, M., Gerritsen, H., Spek, C. A., Brandjes, D. P. M., ten Cate, H., Bossuyt, P. M., Reitsma, P. H., & van Gorp, E. C. M. (2010). Additional value of procalcitonin for diagnosis of infection in patients with fever at the emergency department. Critical Care Medicine, 38(2), 457-463. https://doi.org/10.1097/CCM.0b013e3181b9ec33

Castoldi, E., Simioni, P., Tormene, D., Rosing, J., & Hackeng, T. M. (2010). Hereditary and acquired protein S deficiencies are associated with low TFPI levels in plasma. Journal of Thrombosis and Haemostasis, 8(2), 294-300. https://doi.org/10.1111/j.1538-7836.2009.03712.x

Schols, S. E. M., Lance, M. D., Feijge, M. A. H., Damoiseaux, J., Marcus, M. A., Hamulyak, K., ten Cate, H., Heemskerk, J. W. M., & van Pampus, E. C. M. (2010). Impaired thrombin generation and fibrin clot formation in patients with dilutional coagulopathy during major surgery. Thrombosis and Haemostasis, 103(2), 318-328. https://doi.org/10.1160/TH09-06-0396

de Kruif, M. D., Limper, M., Sierhuis, K., Wagenaar, J. F. P., Spek, C. A., Garlanda, C., Cotena, A., Mantovani, A., ten Cate, H., Reitsma, P. H., & van Gorp, E. C. M. (2010). PTX3 predicts severe disease in febrile patients at the emergency department. Journal of Infection, 60(2), 122-127. https://doi.org/10.1016/j.jinf.2009.11.010

Engelen, L., Ferreira, I., Gaens, K. H. J., Henry, R. M. A., Dekker, J. M., Nijpels, G., Heine, R. J., 't Hart, L. M., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Blaak, E. E., Feskens, E. J. M., ten Cate, H., Stehouwer, C. D. A., & Schalkwijk, C. G. (2010). The association between the-374T/A polymorphism of the receptor for advanced glycation endproducts gene and blood pressure and arterial stiffness is modified by glucose metabolism status: the Hoorn and CoDAM studies. Journal of Hypertension, 28(2), 285-293. https://doi.org/10.1097/HJH.0b013e3283330931

Koenen, R. R., & Weber, C. (2010). Therapeutic targeting of chemokine interactions in atherosclerosis. Nature Reviews Drug Discovery, 9(2), 141-153. https://doi.org/10.1038/nrd3048

Duckers, C., Simioni, P., Spiezia, L., Radu, C. M., Dabrilli, P., Gavasso, S., Rosing, J., & Castoldi, E. (2010). Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptoms. Blood, 115(4), 879-886. https://doi.org/10.1182/blood-2009-08-237719

Wijnen, P. A. H. M., Bekers, O., & Drent, M. (2010). 'Drug'-induced pneumonitis associated with CYP and VKORC1 variants.The Bulletin of contemporary clinical medicine, 3, 15-17. https://doi.org/10.20969/VSKM.2010.3(4).15-17

Jacobs, L. H., van de Kerkhof, J. J., Mingels, A. M., Lima Passos, V., Kleijnen, V. W., Mazairac, A. H., van der Sande, F. M., Wodzig, W. K., Konings, C. J., Leunissen, K. M., van Dieijen-Visser, M. P., & Kooman, J. P. (2010). Inflammation, overhydration and cardiac biomarkers in haemodialysis patients: a longitudinal study.Nephrology Dialysis Transplantation, 25(1), 243-248. https://doi.org/10.1093/ndt/gfp417

Lobbes, M. B., Kooi, M. E., Lutgens, E., Lima Passos, V., Braat, S. H. J. G., Rousch, M. J. M., ten Cate, H., van Engelshoven, J. M., Daemen, M. J., & Heeneman, S. (2010). Leukocyte counts, myeloperoxidase, and pregnancy-associated plasma protein a as biomarkers for cardiovascular disease: towards a multi-biomarker approach.International Journal of Vascular Medicine, 2010(726207). https://doi.org/10.1155/2010/726207

Wijnen, P. A., Bekers, O., van Dieijen-Visser, M. P., & Drent, M. (2010). Pharmacogenetic testing after a simple DNA isolation method.The Bulletin of contemporary clinical medicine, 3, 9-14. https://doi.org/10.20969/VSKM.2010.3(4).9-14

Wisse, W., Rookhuizen, M. B., de Kruif, M. D., van Rossum, J., Jordans, I., ten Cate, H., van Loon, L. J. C., & Meesters, E. W. (2010). Prescription of physical activity is not sufficient to change sedentary behavior and improve glycemic control in type 2 diabetes patients.Diabetes Research and Clinical Practice, 88(2), E10-13. https://doi.org/10.1016/j.diabres.2010.01.015

Wijnen, P. A., Linssen, C. F., Haenen, G. R., Bekers, O., & Drent, M. (2010). Variant VKORC1 and CYP2C9 Alleles in Patients with Diffuse Alveolar Hemorrhage Caused by Oral Anticoagulants. Molecular Diagnosis & Therapy, 14(1), 23-30. https://doi.org/10.1007/BF03256350

Pilz, S., Henry, R. M., Snijder, M. B., van Dam, R. M., Nijpels, G., Stehouwer, C. D. A., Kamp, O., Tomaschitz, A., Pieber, T. R., & Dekker, J. M. (2010). Vitamin D deficiency and myocardial structure and function in older men and women: The Hoorn Study.Journal of Endocrinological Investigation, 33(9), 612-617. https://doi.org/10.1007/BF03346658

Segers, O., van Oerle, R., ten Cate, H., Rosing, J., & Castoldi, E. (2010). Thrombin generation as an intermediate phenotype for venous thrombosis A proof-of-concept study. Thrombosis and Haemostasis, 103(1), 114-122. https://doi.org/10.1160/TH09-06-0356

Megens, R. T. A., Reitsma, S., Prinzen, L., Egbrink, M. G. A. O., Engels, W., Leenders, P. J. A., Brunenberg, E. J. L., Reesink, K. D., Janssen, B. J. A., Romeny, B. M. T. H., Slaaf, D. W., & van Zandvoort, M. A. M. J. (2010). In vivo high-resolution structural imaging of large arteries in small rodents using two-photon laser scanning microscopy. Journal of Biomedical Optics, 15(1), 10. Article 011108. https://doi.org/10.1117/1.3281672

Van de Vijver, P., Suylen, D. P., Dirksen, A., Dawson, P. E., & Hackeng, T. M. (2010). N-epsilon-(Thiaprolyl)-lysine as a Handle for Site-Specific Protein Conjugation. Biopolymers, 94(4), 465-474. https://doi.org/10.1002/bip.21485

Oostendorp, M., Douma, K., Hackeng, T. M., van Zandvoort, M. A. M. J., Post, M. J., & Backes, W. H. (2010). Pharmacokinetics of contrast agents targeted to the tumor vasculature in molecular magnetic resonance imaging. Contrast Media & Molecular Imaging, 5(1), 9-17. https://doi.org/10.1002/cmmi.361

Senen, K., Topal, E., Kilinc, E., ten Cate, H., Tek, I., Karakoc, Y., & Yetkin, E. (2010). Plasma viscosity and mean platelet volume in patients undergoing coronary angiography. Clinical Hemorheology and Microcirculation, 44(1), 35-41. https://doi.org/10.3233/CH-2010-1249

Pilz, S., Henry, R. M., Snijder, M. B., van Dam, R. M., Nijpels, G., Stehouwer, C. D., Tomaschitz, A., Pieber, T. R., & Dekker, J. M. (2009). 25-Hydroxyvitamin D is not Associated with Carotid Intima-Media Thickness in Older Men and Women. Calcified Tissue International, 84(5), 423-424. https://doi.org/10.1007/s00223-009-9238-6

Klomp, C. M., ten Cate, H., Stehouwer, C. D., & Schaper, N. C. (2009). Acetylsalicylzuur bij patienten met diabetes mellitus: niet voor primaire, wel voor secundaire preventie van hart-vaatziekten. Nederlands Tijdschrift voor Geneeskunde, 153, A109. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19785798

Wijnen, P. A., Limantoro, I., Drent, M., Bekers, O., Kuijpers, P. M., & Koek, G. H. (2009). Depressive effect of an antidepressant: therapeutic failure of venlafaxine in a case lacking CYP2D6 activity. Annals of Clinical Biochemistry, 46(Pt 6), 527-30. https://doi.org/10.1258/acb.2009.009003

Wolfs, J. L., Comfurius, P., Bekers, O., Zwaal, R. F., Balasubramanian, K., Schroit, A. J., Lindhout, T., & Bevers, E. M. (2009). Direct inhibition of phospholipid scrambling activity in erythrocytes by potassium ions. Cellular and Molecular Life Sciences, 66(2), 314-23. https://doi.org/10.1007/s00018-008-8566-4